Cynthia A. Reinhart-King

发表

Single cell-mediated collagen reorganization in 3D matrices

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Faculty Opinions recommendation of Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration.

Cynthia A. Reinhart-King, 2017 .

The 2015 Young Innovators of Cellular and Molecular Bioengineering

Cynthia A. Reinhart-King, Nicholas A. Peppas, Christine E. Schmidt, 2015, Cellular and molecular bioengineering.

TRACTION FORCES EXERTED BY ADHERENT CELLS

Daniel A. Hammer, Cynthia A. Reinhart-King, C. Reinhart-King, 2006 .

Approaches to Manipulating the Dimensionality and Physicochemical Properties of Common Cellular Scaffolds

Na Young Kim, Cynthia A. Reinhart-King, Saumendra Bajpai, 2011, International journal of molecular sciences.

Mechanical Cell-Matrix Feedback Explains Pairwise and Collective Endothelial Cell Behavior In Vitro

Roeland M. H. Merks, Roeland Merks, Cynthia A. Reinhart-King, 2013, PLoS Comput. Biol..

Author Correction: Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making

David Erickson, Cynthia A. Reinhart-King, Matthew R. Zanotelli, 2019, Nature Communications.

Engineered models to parse apart the metastatic cascade

Cynthia A. Reinhart-King, Lauren A. Hapach, Jenna A. Mosier, 2019, npj Precision Oncology.

Faculty Opinions recommendation of Time series modeling of live-cell shape dynamics for image-based phenotypic profiling.

Cynthia A. Reinhart-King, 2016 .

Endothelial Cell Traction Forces on RGD-Derivatized Polyacrylamide Substrata †

Daniel A. Hammer, Cynthia A. Reinhart-King, C. Reinhart-King, 2003 .

3D Bioprinting of Spatially Heterogeneous Collagen Constructs for Cartilage Tissue Engineering.

Cynthia A. Reinhart-King, Lawrence J. Bonassar, L. Bonassar, 2016, ACS biomaterials science & engineering.

Control of cell migration using a conducting polymer device

George G. Malliaras, Cynthia A. Reinhart-King, Alwin M. D. Wan, 2010 .

Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model

Shawn P. Carey, Cynthia A. Reinhart-King, Alina Starchenko, 2013, Clinical & Experimental Metastasis.

Vinculin regulates directionality and cell polarity in two- and three-dimensional matrix and three-dimensional microtrack migration

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2016, Molecular biology of the cell.

Clinical doses of radiation reduce collagen matrix stiffness

Cynthia A. Reinhart-King, Francois Bordeleau, Lawrence J. Bonassar, 2018, APL bioengineering.

A Balance of Substrate Mechanics and Matrix Chemistry Regulates Endothelial Cell Network Assembly

Cynthia A. Reinhart-King, C. Reinhart-King, Joseph P. Califano, 2008 .

Matrix Stiffness: A Regulator of Cellular Behavior and Tissue Formation

Cynthia A. Reinhart-King, C. Reinhart-King, Brooke N. Mason, 2012 .

Substrate Stiffness and Cell Area Predict Cellular Traction Stresses in Single Cells and Cells in Contact

Cynthia A. Reinhart-King, C. Reinhart-King, Joseph P. Califano, 2010, Cellular and molecular bioengineering.

Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials

Cynthia A. Reinhart-King, C. Reinhart-King, Marsha C Lampi, 2018, Science Translational Medicine.

Microfabricated Physical Spatial Gradients for Investigating Cell Migration and Invasion Dynamics

David Erickson, Cynthia A. Reinhart-King, Michael Mak, 2011, PloS one.

The effects of substrate elasticity on endothelial cell network formation and traction force generation

Cynthia A. Reinhart-King, C. Reinhart-King, Joseph P. Califano, 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Cellular Traction Stresses Increase with Increasing Metastatic Potential

Casey M. Kraning-Rush, Cynthia A. Reinhart-King, C. Reinhart-King, 2012, PloS one.

Manipulation of in vitro collagen matrix architecture for scaffolds of improved physiological relevance

Cynthia A. Reinhart-King, Jacob A. VanderBurgh, Lauren A. Hapach, 2015, Physical biology.

Tensional homeostasis and the malignant phenotype.

Cynthia A. Reinhart-King, C. Reinhart-King, A. Gefen, 2005, Cancer cell.

Matrix Stiffness Enhances VEGFR-2 Internalization, Signaling, and Proliferation in Endothelial Cells.

Cynthia A. Reinhart-King, Danielle J. LaValley, Matthew R. Zanotelli, 2017, Convergent science physical oncology.

Mechanobiology of microvesicle release, uptake, and microvesicle-mediated activation.

Cynthia A. Reinhart-King, C. Reinhart-King, S. C. Schwager, 2020, Current topics in membranes.

Forces During Cell Adhesion and Spreading: Implications for Cellular Homeostasis

Shawn P. Carey, Cynthia A. Reinhart-King, C. Reinhart-King, 2010 .

Fluid shear stress enhances T cell activation through Piezo1

Cynthia A. Reinhart-King, Jacob M. Hope, C. Reinhart-King, 2022, BMC Biology.

Matrix stiffness regulates vascular integrity through focal adhesion kinase activity

Cynthia A. Reinhart-King, C. Reinhart-King, François Bordeleau, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cell Migration in Microfabricated 3D Collagen Microtracks is Mediated Through the Prometastatic Protein Girdin

Cynthia A. Reinhart-King, C. Reinhart-King, Shuo Shan, 2017, Cellular and Molecular Bioengineering.

Topographical guidance of 3D tumor cell migration at an interface of collagen densities

Cynthia A. Reinhart-King, C. Reinhart-King, François Bordeleau, 2013, Physical biology.

Microfabricated collagen tracks facilitate single cell metastatic invasion in 3D.

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2013, Integrative biology : quantitative biosciences from nano to macro.

Traction Force Microscopy for Noninvasive Imaging of Cell Forces.

Cynthia A. Reinhart-King, Jeffrey A Mulligan, François Bordeleau, 2018, Advances in experimental medicine and biology.

The dynamics and mechanics of endothelial cell spreading.

Micah Dembo, Cynthia A. Reinhart-King, Cynthia A Reinhart-King, 2005, Biophysical journal.

Forces exerted and transduced by cancer‐associated fibroblasts during cancer progression

Cynthia A. Reinhart-King, C. Reinhart-King, Sarah Libring, 2023, Biology of the cell.

Mechanical Forces in Tumor Angiogenesis.

Cynthia A. Reinhart-King, Matthew R. Zanotelli, C. Reinhart-King, 2018, Advances in experimental medicine and biology.

Cancer cell metabolic plasticity in migration and metastasis

Cynthia A. Reinhart-King, C. Reinhart-King, Jenna A. Mosier, 2021, Clinical & Experimental Metastasis.

Mechanoresponsive metabolism in cancer cell migration and metastasis.

Cynthia A. Reinhart-King, Matthew R. Zanotelli, C. Reinhart-King, 2021, Cell metabolism.

Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype

Shawn P. Carey, Cynthia A. Reinhart-King, C. Reinhart-King, 2017, Scientific Reports.

The Mechanics of Single Cell and Collective Migration of Tumor Cells.

Cynthia A. Reinhart-King, C. Reinhart-King, Marianne Lintz, 2017, Journal of biomechanical engineering.

Local extracellular matrix alignment directs cellular protrusion dynamics and migration through Rac1 and FAK.

Shawn P. Carey, Cynthia A. Reinhart-King, Cynthia A Reinhart-King, 2016, Integrative biology : quantitative biosciences from nano to macro.

Microvesicles released from tumor cells disrupt epithelial cell morphology and contractility.

Cynthia A. Reinhart-King, C. Reinhart-King, R. Cerione, 2016, Journal of biomechanics.

Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks.

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2015, American journal of physiology. Cell physiology.

Physical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topography.

Cynthia A. Reinhart-King, C. Reinhart-King, Turi A. Alcoser, 2014, American journal of physiology. Cell physiology.

Mechanobiology of tumor invasion: engineering meets oncology.

Shawn P. Carey, Cynthia A. Reinhart-King, Timothy D’alfonso, 2012, Critical reviews in oncology/hematology.

Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture.

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2012, Biomaterials.

Controlling matrix stiffness and topography for the study of tumor cell migration

Casey M. Kraning-Rush, Cynthia A. Reinhart-King, C. Reinhart-King, 2012, Cell adhesion & migration.

Physical Biology of Cancer Comparative mechanisms of cancer cell migration through 3 D matrix and physiological microtracks

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2015 .

The rocky road of metastasis : the role of cytoskeletal mechanics in cell migratory response to 3 D matrix topography

Cynthia A. Reinhart-King, C. Reinhart-King, Turi A. Alcoser, 2013 .

Quantifying traction stresses in adherent cells.

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2012, Methods in cell biology.

Matrix stiffness induces epithelial-to-mesenchymal transition via Piezo1-regulated calcium flux in prostate cancer cells

Cynthia A. Reinhart-King, Jacob A. VanderBurgh, Jacob M. Hope, 2023, iScience.

Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption

Cynthia A. Reinhart-King, Matthew R. Zanotelli, C. Reinhart-King, 2016, PloS one.

Cynthia A. Reinhart-King, C. Reinhart-King, Marsha C Lampi, 2015, Front. Genet..

Cooperative effects of matrix stiffness and fluid shear stress on endothelial cell behavior.

Cynthia A. Reinhart-King, C. Reinhart-King, M. King, 2015, Biophysical journal.

Cynthia A. Reinhart-King, C. Reinhart-King, N. Nishimura, 2011, Science Translational Medicine.

Indentation measurements of the subendothelial matrix in bovine carotid arteries.

Cynthia A. Reinhart-King, C. Reinhart-King, Rebecca M. Williams, 2011, Journal of biomechanics.

Mitochondrial transfer from cancer-associated fibroblasts increases migration in aggressive breast cancer

Cynthia A. Reinhart-King, C. Reinhart-King, T. Gaborski, 2023, Journal of cell science.

Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment.

Cynthia A. Reinhart-King, Paul V. Taufalele, Austin N. Southard-Smith, 2022, Acta biomaterialia.

Microscale Interrogation of 3D Tissue Mechanics

Cynthia A. Reinhart-King, C. Reinhart-King, Neil C Chada, 2019, Front. Bioeng. Biotechnol..

Extent of Cell Confinement in Microtracks Affects Speed and Results in Differential Matrix Strains.

Cynthia A. Reinhart-King, Matthew R. Zanotelli, Jacob A. VanderBurgh, 2019, Biophysical journal.

The role of the cytoskeleton in cellular force generation in 2D and 3D environments

Shawn P. Carey, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2011, Physical biology.

Cell-cell mechanical communication through compliant substrates.

Micah Dembo, Cynthia A. Reinhart-King, Cynthia A Reinhart-King, 2008, Biophysical journal.

Phenotypic Heterogeneity and Metastasis of Breast Cancer Cells

Shawn P. Carey, Cynthia A. Reinhart-King, Paul V. Taufalele, 2021, Cancer Research.

Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making

Cynthia A. Reinhart-King, Matthew R. Zanotelli, Jacob A. VanderBurgh, 2019, Nature Communications.

Dynamic heterodimer-functionalized surfaces for endothelial cell adhesion.

Cynthia A. Reinhart-King, Cynthia A Reinhart-King, Daniel A Hammer, 2005, Biomaterials.

Implanted adipose progenitor cells as physicochemical regulators of breast cancer

Cynthia A. Reinhart-King, Mark R. Buckley, C. Reinhart-King, 2012, Proceedings of the National Academy of Sciences.

Cell–Cell Mechanical Communication in Cancer

Cynthia A. Reinhart-King, Paul V. Taufalele, C. Reinhart-King, 2018, Cellular and Molecular Bioengineering.

Matrix stiffening promotes a tumor vasculature phenotype

Cynthia A. Reinhart-King, Robert S Weiss, Francois Bordeleau, 2016, Proceedings of the National Academy of Sciences.

Fiber alignment drives changes in architectural and mechanical features in collagen matrices

Cynthia A. Reinhart-King, Matthew R. Zanotelli, Jacob A. VanderBurgh, 2019, PloS one.

Highly motile cells are metabolically responsive to collagen density

Cynthia A. Reinhart-King, Matthew R. Zanotelli, C. Reinhart-King, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Matrix-driven changes in metabolism support cytoskeletal activity to promote cell migration.

Cynthia A. Reinhart-King, Matthew R. Zanotelli, C. Reinhart-King, 2021, Biophysical journal.

The Physical Microenvironment of Tumors: Characterization and Clinical Impact

Cynthia A. Reinhart-King, Matthew R. Zanotelli, C. Reinhart-King, 2020, The Physics of Cancer.

Regulation of ATP utilization during metastatic cell migration by collagen architecture

Cynthia A. Reinhart-King, Matthew R. Zanotelli, Jacob A. VanderBurgh, 2018, Molecular biology of the cell.

Activation of Piezo1 sensitizes cells to TRAIL-mediated apoptosis through mitochondrial outer membrane permeability

Cynthia A. Reinhart-King, Jacob M. Hope, C. Reinhart-King, 2019, Cell Death & Disease.

Self-Assembled Cationic Biodegradable Nanoparticles from pH-Responsive Amino-Acid-Based Poly(Ester Urea Urethane)s and Their Application As a Drug Delivery Vehicle.

Cynthia A. Reinhart-King, C. Reinhart-King, Alicia Potuck, 2016, Biomacromolecules.

Synthesis and characterization of biodegradable poly(ester amide)s with pendant amine functional groups and in vitro cellular response.

Cynthia A. Reinhart-King, C. Reinhart-King, C. Chu, 2009, Biomacromolecules.

Tuning cell migration: contractility as an integrator of intracellular signals from multiple cues

Cynthia A. Reinhart-King, C. Reinhart-King, François Bordeleau, 2016, F1000Research.

Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA

Cynthia A. Reinhart-King, Paul V. Taufalele, C. Reinhart-King, 2023, Cell reports.

Energetic regulation of coordinated leader–follower dynamics during collective invasion of breast cancer cells

Cynthia A. Reinhart-King, Paul V. Taufalele, C. Reinhart-King, 2019, Proceedings of the National Academy of Sciences.

Exogenous and endogenous force regulation of endothelial cell behavior.

Cynthia A. Reinhart-King, Cynthia A Reinhart-King, C. Reinhart-King, 2010, Journal of biomechanics.

Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation

Cynthia A. Reinhart-King, C. Reinhart-King, R. Cerione, 2016, Nature Communications.

High type I collagen density fails to increase breast cancer stem cell phenotype

Cynthia A. Reinhart-King, C. Reinhart-King, François Bordeleau, 2020, PeerJ.

Substrate Stiffness Regulates PDGF-Induced Circular Dorsal Ruffle Formation Through MLCK

Casey M. Kraning-Rush, Cynthia A. Reinhart-King, C. Reinhart-King, 2013, Cellular and molecular bioengineering.

Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis

Cynthia A. Reinhart-King, Lauren A. Hapach, C. Reinhart-King, 2021, bioRxiv.

Matrix stiffness regulates microvesicle-induced fibroblast activation.

Cynthia A. Reinhart-King, C. Reinhart-King, R. Cerione, 2019, American journal of physiology. Cell physiology.

The Nucleus Bypasses Obstacles by Deforming Like a Drop with Surface Tension Mediated by Lamin A/C

Cynthia A. Reinhart-King, C. Reinhart-King, R. Dickinson, 2022, bioRxiv.

Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model

Shawn P. Carey, Cynthia A. Reinhart-King, C. Reinhart-King, 2013, Clinical & Experimental Metastasis.

Tissue transglutaminase 2 regulates tumor cell tensional homeostasis by increasing contractility

Cynthia A. Reinhart-King, C. Reinhart-King, R. Cerione, 2019, Journal of Cell Science.

Arterial Stiffening Precedes Systolic Hypertension in Diet-Induced Obesity

Cynthia A. Reinhart-King, C. Reinhart-King, G. Mitchell, 2013, Hypertension.

Biophysical Induction of Vascular Smooth Muscle Cell Podosomes

Shawn P. Carey, Cynthia A. Reinhart-King, C. Reinhart-King, 2015, PloS one.

A discrete interface in matrix stiffness creates an oscillatory pattern of endothelial monolayer disruption

Cynthia A. Reinhart-King, Jacob A. VanderBurgh, C. Reinhart-King, 2020, Journal of Cell Science.

Substrate stiffness heterogeneities disrupt endothelial barrier integrity in a micropillar model of heterogeneous vascular stiffening.

Cynthia A. Reinhart-King, Jacob A. VanderBurgh, Paul V. Taufalele, 2018, Integrative biology : quantitative biosciences from nano to macro.

Determining mechanical features of modulated epithelial monolayers using subnuclear particle tracking

Cynthia A. Reinhart-King, C. Reinhart-King, K. Dahl, 2018, Journal of Cell Science.

The Role of Age-Related Intimal Remodeling and Stiffening in Atherosclerosis.

Cynthia A. Reinhart-King, Jacob A. VanderBurgh, C. Reinhart-King, 2018, Advances in pharmacology.

Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors

Cynthia A. Reinhart-King, Danielle J. LaValley, C. Reinhart-King, 2015, Proceedings of the National Academy of Sciences.

Subcellular regulation of cancer cell mechanics

Cynthia A. Reinhart-King, Matthew R. Zanotelli, C. Reinhart-King, 2017 .

Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening

Cynthia A. Reinhart-King, Andrew C Johnson, Paul V. Taufalele, 2022, Science advances.

Inducing Apoptosis in Rolling Cancer Cells: A Combined Therapy with Aspirin and Immobilized TRAIL and E-Selectin

Cynthia A. Reinhart-King, C. Reinhart-King, M. King, 2012, Molecular pharmaceutics.

Controlling the mechanical properties of three-dimensional matrices via non-enzymatic collagen glycation

Cynthia A. Reinhart-King, C. Reinhart-King, Brooke N. Mason, 2013, Organogenesis.

Tuning three-dimensional collagen matrix stiffness independently of collagen concentration modulates endothelial cell behavior.

Cynthia A. Reinhart-King, Cynthia A Reinhart-King, Lawrence J Bonassar, 2013, Acta biomaterialia.

Tuning 3D Collagen Matrix Stiffness Independently of Collagen Concentration Modulates Endothelial Cell Behavior

Cynthia A. Reinhart-King, L. Bonassar, C. Reinhart-King, 2012 .

Cellular mechanosignaling for sensing and transducing matrix rigidity.

Cynthia A. Reinhart-King, C. Reinhart-King, Katherine M. Young, 2023, Current opinion in cell biology.

Recent advances in understanding the role of metabolic heterogeneities in cell migration

Cynthia A. Reinhart-King, C. Reinhart-King, Jenna A. Mosier, 2021, Faculty reviews.

Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device.

David Erickson, Cynthia A. Reinhart-King, Michael Mak, 2013, Lab on a chip.

Link between glucose metabolism and epithelial-to-mesenchymal transition drives triple-negative breast cancer migratory heterogeneity

Cynthia A. Reinhart-King, Paul V. Taufalele, Lauren A. Hapach, 2022, iScience.

Photopatterned Hydrogels to Investigate the Endothelial Cell Response to Matrix Stiffness Heterogeneity.

Cynthia A. Reinhart-King, J. Burdick, M. Guvendiren, 2017, ACS biomaterials science & engineering.

Cancer-associated fibroblasts in early-stage lung adenocarcinoma correlate with tumor aggressiveness

Cynthia A. Reinhart-King, P. Massion, S. Antic, 2023, Scientific reports.

Targeting Tissue Stiffness in Metastasis: Mechanomedicine Improves Cancer Therapy.

Cynthia A. Reinhart-King, C. Reinhart-King, Jian Zhang, 2020, Cancer cell.

Physiologic stress-mediated signaling in the endothelium.

Cynthia A. Reinhart-King, C. Reinhart-King, K. Fujiwara, 2008, Methods in enzymology.

Lysyl oxidase-like 1 deficiency alters ultrastructural and biomechanical properties of the peripapillary sclera in mice

Cynthia A. Reinhart-King, C. Reinhart-King, J. Kuchtey, 2022, Matrix biology plus.

A physical sciences network characterization of non-tumorigenic and metastatic cells

Christopher S. Poultney, Casey M. Kraning-Rush, Cynthia A. Reinhart-King, 2013, Scientific Reports.

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression

Cynthia A. Reinhart-King, Jacob M. Hope, C. Reinhart-King, 2020, Oncotarget.