H. van der Gulden

发表

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer

J. Peterse, A. Berns, L. Wessels, 2007, Proceedings of the National Academy of Sciences.

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.

A. Berns, J. Jonkers, M. Vooijs, 2000, Genes & development.

Characterization and Functional Analysis of the Murine Frat2 Gene*

A. Berns, J. Jonkers, R. van Amerongen, 2004, Journal of Biological Chemistry.

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

Peter Bouwman, Christiaan Klijn, Jos Jonkers, 2011, Cancer cell.

Effect of macromolecular composition of microorganisms on the thermodynamic description of their growth.

M. M. Mulder, P. Postma, K. van Dam, 1988, Biochimica et biophysica acta.

Continued growth of Escherichia coli after stopping medium addition to a K+-limited chemostat culture.

M. M. Mulder, P. Postma, K. van Dam, 1988, Journal of general microbiology.

Live attenuated pseudorabies virus expressing envelope glycoprotein E1 of hog cholera virus protects swine against both pseudorabies and hog cholera

A. Berns, A. Gielkens, M. Hulst, 1991, Journal of virology.

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

Jos Jonkers, Robert D Cardiff, Bastiaan Evers, 2006, Cancer cell.

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.

R. Elkon, Jeroen A. A. Demmers, R. Agami, 2016, The Journal of clinical investigation.

The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.

Y. Wang, B. Karlan, J. Benítez, 2016, Cancer research.

A high-throughput functional complementation assay for classification of BRCA1 missense variants.

Peter Bouwman, Jos Jonkers, I. van der Heijden, 2013, Cancer discovery.

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

D. Adams, S. Hiddingh, H. Nevanlinna, 2010, Nature Structural &Molecular Biology.

Functional Categorization of BRCA1 Variants of Uncertain Clinical Significance in Homologous Recombination Repair Complementation Assays

S. Seneca, L. Wessels, M. Blok, 2020, Clinical Cancer Research.

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

I. Huijbers, H. van Attikum, J. Jonkers, 2021, Cancer Research.

Somatic structural rearrangements in genetically engineered mouse mammary tumors

M. Stratton, P. Futreal, P. Campbell, 2010, Genome Biology.

Identification of two genes in the unique short region of pseudorabies virus; comparison with herpes simplex virus and varicella-zoster virus.

N. de Wind, A. Berns, A. Gielkens, 1990, The Journal of general virology.

Prophylactic window therapy with the clinical poly(ADP‐ribose) polymerase inhibitor olaparib delays BRCA1‐deficient mammary tumour formation in mice

J. Jonkers, M. van de Ven, H. van der Gulden, 2016, The Journal of pathology.

Frat is dispensable for canonical Wnt signaling in mammals.

A. Berns, M. Nawijn, Jonathan Franca-Koh, 2005, Genes & development.

Thermodynamic efficiency of bacterial growth calculated from growth yield of Pseudomonas oxalaticus OX1 in the chemostat.

K. van Dam, M. Rutgers, H. van der Gulden, 1989, Biochimica et biophysica acta.

A high-throughput functional complementation assay for classification of BRCA1 missense variants.

J. Jonkers, F. Hogervorst, C. Klijn, 2013, Cancer discovery.

Edinburgh Research Explorer The BRCA1-11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.

B. Karlan, J. Benítez, P. Pharoah, 2018 .