M. Lerche

发表

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

J. Ardenkjær-Larsen, B. Fridlund, Andreas Gram, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

Pernille R. Jensen, Mathilde H. Lerche, Ferdia A. Gallagher, 2008, Nature.

Generating highly polarized nuclear spins in solution using dynamic nuclear polarization

Mathilde H. Lerche, Jan Wolber, Jan Henrik Ardenkjær-Larsen, 2004 .

Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis.

Jan Henrik Ardenkjaer-Larsen, J. Ardenkjaer-Larsen, R. Pehrson, 2006, Cancer research.

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy

Jan Wolber, Ferdia A Gallagher, Kevin M Brindle, 2007, Nature Medicine.

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors

Sarah E Bohndiek, Ferdia A Gallagher, Kevin M Brindle, 2009, Proceedings of the National Academy of Sciences.

Non-invasive In-cell Determination of Free Cytosolic [NAD+]/[NADH] Ratios Using Hyperpolarized Glucose Show Large Variations in Metabolic Phenotypes*

J. Winther, P. Jensen, M. Lerche, 2013, The Journal of Biological Chemistry.

Study of molecular interactions with 13C DNP-NMR.

J. Ardenkjaer-Larsen, S. Meier, J. Duus, 2010, Journal of magnetic resonance.

NMR insights into the inner workings of living cells.

S. Meier, P. Jensen, M. Lerche, 2015, Analytical chemistry.

Deuteration of a molecular probe for DNP hyperpolarization--a new approach and validation for choline chloride.

R. Lenkinski, R. Katz‐Brull, M. Lerche, 2011, Contrast media & molecular imaging.

Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization

J. Ardenkjær-Larsen, F. Vibert, M. Lerche, 2021, Communications Chemistry.

Efficient Hyperpolarization of U-13 C-Glucose Using Narrow-Line UV-Generated Labile Free Radicals.

J. Ardenkjaer-Larsen, M. Lerche, O. Ouari, 2018, Angewandte Chemie.

Liquid-State 13C Polarization of 30% through Photoinduced Nonpersistent Radicals

J. R. Petersen, J. Ardenkjær-Larsen, M. Lerche, 2018 .

Pulse sequences for measurement of one-bond (15)N-(1)H coupling constants in the protein backbone.

F. Poulsen, O. W. Sørensen, M. Lerche, 1999, Journal of magnetic resonance.

Detection of myocardial medium‐chain fatty acid oxidation and tricarboxylic acid cycle activity with hyperpolarized [1–13C]octanoate

J. Schwitter, H. Yoshihara, M. Lerche, 2020, NMR in biomedicine.

Development of Dissolution DNP-MR Substrates for Metabolic Research

S. Meier, J. Duus, P. Jensen, 2012 .

Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized 13C magnetic resonance

R. Gruetter, A. Sherry, Z. Kovács, 2017, Scientific Reports.

spectroscopy C-nuclear magnetic resonance 13 analysis by Oxidation of lactate and acetate in rat skeletal muscle:

Chi-An W. Emhoff, G. Brooks, H. Degani, 2015 .

UV-Irradiated 2-Keto-(1-13C)Isocaproic Acid for High-Performance 13C Hyperpolarized MR

J. Ardenkjær-Larsen, M. Lerche, M. Karlsson, 2020, The Journal of Physical Chemistry C.

CMR2009: 7.02: Hyperpolarized 1,4-13C2 fumarate – a new diagnostic agent for oncology

P. Jensen, G. Hansson, M. Lerche, 2009 .

High-field dissolution dynamic nuclear polarization of [1-(13)C]pyruvic acid.

J. Schwitter, H. Yoshihara, M. Lerche, 2016, Physical chemistry chemical physics : PCCP.

Dissolution Dynamic Nuclear Polarization capability study with fluid path.

J. Ardenkjær-Larsen, M. Lerche, K. Lipsø, 2016, Journal of magnetic resonance.

A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis.

J. Gomori, R. Katz‐Brull, M. Lerche, 2011, Contrast media & molecular imaging.

Quantitative Evaluation of the Cellular Uptake of Nanodiamonds by Monocytes and Macrophages

K. Berg-Sørensen, M. Dufva, M. Lerche, 2022, bioRxiv.

Hyperpolarized 133Cs is a sensitive probe for real-time monitoring of biophysical environments.

J. Ardenkjær-Larsen, M. Lerche, M. Karlsson, 2017, Chemical communications.

Increase of signal-to-noise of more than 10,000 times in liquid state NMR.

J. Wolber, J. Ardenkjær-Larsen, Andreas Gram, 2003, Discovery medicine.

Gadolinium Effect at High-Magnetic-Field DNP: 70% 13C Polarization of [U-13C] Glucose Using Trityl.

J. Ardenkjær-Larsen, M. Lerche, M. Karlsson, 2019, The journal of physical chemistry letters.

Preparation of Radical-Free Hyperpolarized Water using Photo-induced non-persistent Radicals on a “SpinLab-like” dissolution-DNP Polarizer

J. Ardenkjær-Larsen, M. Lerche, M. Karlsson, 2017 .

Difference between Extra- and Intracellular T1 Values of Carboxylic Acids Affects the Quantitative Analysis of Cellular Kinetics by Hyperpolarized NMR.

J. Ardenkjaer-Larsen, P. Jensen, M. Lerche, 2016, Angewandte Chemie.

Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate

S. Meier, J. Duus, P. Jensen, 2010, International journal of cancer.

Barley Lipid Transfer Protein, LTP1, Contains a New Type of Lipid-like Post-translational Modification*

K. Lindorff-Larsen, P. Roepstorff, J. Winther, 2001, The Journal of Biological Chemistry.

Metabolic pathway visualization in living yeast by DNP-NMR.

S. Meier, J. Duus, P. Jensen, 2011, Molecular bioSystems.

Barley lipid-transfer protein complexed with palmitoyl CoA: the structure reveals a hydrophobic binding site that can expand to fit both large and small lipid-like ligands.

F M Poulsen, B. Kragelund, F. Poulsen, 1997, Structure.

Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5‐13C]glutamine

E. Terreno, P. Jensen, M. Lerche, 2015, Magnetic resonance in medicine.

Solution structure of barley lipid transfer protein complexed with palmitate. Two different binding modes of palmitate in the homologous maize and barley nonspecific lipid transfer proteins

F. Poulsen, M. Lerche, 1998, Protein science : a publication of the Protein Society.

In vivo and in vitro liver cancer metabolism observed with hyperpolarized [5-(13)C]glutamine.

L. Venturi, P. Jensen, M. Lerche, 2013, Journal of magnetic resonance.

Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides

Mathilde H. Lerche, Søren Østergaard, Flemming M. Poulsen, 1999, Nature Biotechnology.

Measuring Glycolytic Activity with Hyperpolarized [2H7, U-13C6] D-Glucose in the Naive Mouse Brain under Different Anesthetic Conditions

R. Gruetter, M. Lerche, M. Mishkovsky, 2021, Metabolites.

Hyperpolarized [1,3‐13C2]ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer

L. Venturi, P. Jensen, M. Lerche, 2013, International journal of cancer.

13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C‐labeled glutamine

F. Gallagher, K. Brindle, M. Lerche, 2008, Magnetic resonance in medicine.

Pancreatic β-cells respond to fuel pressure with an early metabolic switch

S. Meier, J. Ardenkjær-Larsen, T. Mandrup-Poulsen, 2020, Scientific Reports.

Hyperpolarized NMR Probes for Biological Assays

Sebastian Meier, Pernille R. Jensen, Magnus Karlsson, 2014, Sensors.

Quantitative dynamic nuclear polarization‐NMR on blood plasma for assays of drug metabolism

S. Meier, J. Ardenkjær-Larsen, J. Duus, 2011, NMR in biomedicine.

Tissue-specific Short Chain Fatty Acid Metabolism and Slow Metabolic Recovery after Ischemia from Hyperpolarized NMR in Vivo*

S. Meier, P. Jensen, G. Hansson, 2009, The Journal of Biological Chemistry.

Hyperpolarized amino acids for in vivo assays of transaminase activity.

S. Meier, J. Duus, P. Jensen, 2009, Chemistry.

Detection of low-populated reaction intermediates with hyperpolarized NMR.

J. Ardenkjaer-Larsen, S. Meier, J. Duus, 2009, Chemical communications.

Erratum to 'Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides”

V. Berezin, E. Bock, V. Kiselyov, 2000, Nature Biotechnology.

Stable isotope resolved metabolomics classification of prostate cancer cells using hyperpolarized NMR data.

J. Ardenkjær-Larsen, P. Jensen, M. Lerche, 2020, Journal of magnetic resonance.

Detection of tumor glutamate metabolism in vivo using 13C magnetic resonance spectroscopy and hyperpolarized [1‐13C]glutamate

F. Gallagher, K. Brindle, M. Lerche, 2011, Magnetic resonance in medicine.

Formate Metabolism in Shigella flexneri and Its Effect on HeLa Cells at Different Stages during the Infectious Process

J. Ardenkjær-Larsen, P. Jensen, M. Lerche, 2023, Microbiology spectrum.

Rapid zero-trans kinetics of Cs+ exchange in human erythrocytes quantified by dissolution hyperpolarized 133Cs+ NMR spectroscopy

P. Kuchel, J. Ardenkjaer-Larsen, M. Lerche, 2019, Scientific Reports.

Identification of Intracellular and Extracellular Metabolites in Cancer Cells Using 13C Hyperpolarized Ultrafast Laplace NMR

Guannan Zhang, C. Hilty, S. Ahola, 2018, Analytical chemistry.

Real-time DNP NMR observations of acetic acid uptake, intracellular acidification, and of consequences for glycolysis and alcoholic fermentation in yeast.

S. Meier, P. Jensen, M. Lerche, 2013, Chemistry.

Erratum: Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy

Jan Wolber, Ferdia A Gallagher, Kevin M Brindle, 2007, Nature Medicine.

Classification and biomarker identification of prostate tissue from TRAMP mice with hyperpolarized 13C-SIRA.

T. Andreassen, T. Bathen, J. Ardenkjær-Larsen, 2021, Talanta.

Stable Isotope-Resolved Analysis with Quantitative Dissolution Dynamic Nuclear Polarization.

J. Ardenkjær-Larsen, P. Jensen, M. Lerche, 2018, Analytical chemistry.

Mutations in a single signaling pathway allow cell growth in heavy water.

R. Hartmann-Petersen, J. Winther, B. Kragelund, 2020, ACS synthetic biology.

Mutations in a single signaling pathway allow growth on a different solvent than water

R. Hartmann-Petersen, J. Winther, B. Kragelund, 2019, bioRxiv.

Dissolution Dynamic Nuclear Polarization capability study with fluid path.

J. Ardenkjær-Larsen, M. Lerche, K. Lipsø, 2016, Journal of magnetic resonance.

Targeted Metabolomics with Quantitative Dissolution Dynamic Nuclear Polarization.

J. Ardenkjær-Larsen, P. Jensen, M. Lerche, 2019, Methods in molecular biology.

Improvement of hydrogen bond geometry in protein NMR structures by residual dipolar couplings – an assessment of the interrelation of NMR restraints

J. Axelsen, F. Poulsen, P. Jensen, 2004, Journal of biomolecular NMR.