B. Knuckley

发表

Post-Training Lesions of the Medial Prefrontal Cortex Interfere with Subsequent Performance of Trace Eyeblink Conditioning

J. Churchwell, B. Simon, D. Powell, 2005, The Journal of Neuroscience.

Probing adenylation: using a fluorescently labelled ATP probe to directly label and immunoprecipitate VopS substrates.

M. J. Chalmers, P. Thompson, Daniel M. Lewallen, 2012, Molecular bioSystems.

The development and characterization of a chemical probe targeting PRMT1 over PRMT5.

B. Knuckley, Corey P. Causey, Sarah A. Mann, 2019, Bioorganic & medicinal chemistry.

Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe.

Yuan Luo, P. Thompson, B. Knuckley, 2006, Journal of the American Chemical Society.

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor.

Deepak Poudyal, T. Davis, A. Chumanevich, 2011, American journal of physiology. Gastrointestinal and liver physiology.

A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation.

Yuan Luo, M. Stallcup, P. Thompson, 2006, Journal of the American Chemical Society.

A peptoid-based inhibitor of protein arginine methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells

B. Knuckley, Corey P. Causey, F. Rehman, 2022, The Journal of biological chemistry.

Histone H4-based peptoids are inhibitors of Protein Arginine Methyltransferase 1 (PRMT1).

B. Knuckley, Corey P. Causey, B. May, 2020, The Biochemical journal.

Purification of enzymatically inactive peptidylarginine deiminase type 6 from mouse ovary that reveals hexameric structure different from other dimeric isoforms

P. Thompson, K. Tobe, I. Usui, 2011 .

Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

P. Thompson, B. Knuckley, Justin E. Jones, 2010, Biochemistry.

Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors.

Yuan Luo, P. Thompson, B. Knuckley, 2008, Bioorganic & medicinal chemistry.

Protein arginine deiminase 4: evidence for a reverse protonation mechanism.

P. Thompson, B. Knuckley, M. Bhatia, 2007, Biochemistry.

Mechanistic Studies of Protein Arginine Deiminase 2: Evidence for a Substrate-Assisted Mechanism

P. Thompson, Daniel M. Lewallen, B. Knuckley, 2014, Biochemistry.

N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-l-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

W. Robinson, Yuan Luo, V. M. Holers, 2011, The Journal of Immunology.

Haloacetamidine‐Based Inactivators of Protein Arginine Deiminase 4 (PAD4): Evidence that General Acid Catalysis Promotes Efficient Inactivation

P. Thompson, P. Cook, B. Knuckley, 2010, Chembiochem : a European journal of chemical biology.

Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential.

P. Thompson, B. Knuckley, Justin E. Jones, 2009, Current opinion in drug discovery & development.

Two Distinct Cyclodipeptide Synthases from a Marine Actinomycete Catalyze Biosynthesis of the Same Diketopiperazine Natural Product.

Amy L. Lane, J. Karty, B. Knuckley, 2016, ACS synthetic biology.

Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps.

M. Radic, P. Thompson, T. Mikuls, 2012, Arthritis and rheumatism.

The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors.

Yuan Luo, A. Chumanevich, L. Hofseth, 2011, Journal of medicinal chemistry.

Collagen-Induced Arthritis Inhibitor , Reduces the Severity of Murine hine Amide , a Protein Arginine Deiminase-Benzoyl-N 5-( 2-Chloro-1-Iminoethyl )-l-Ornit α

W. Robinson, Yuan Luo, M. Glogowska, 2011 .

Arthritis Reduces the Severity of Murine Collagen-Induced Amide , a Protein Arginine Deiminase Inhibitor ,-Benzoyl-N 5-( 2-Chloro-1-Iminoethyl )-l-Ornithine

W. Robinson, Yuan Luo, M. Glogowska, 2011 .

Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

Yuan Luo, M. Stallcup, P. Thompson, 2006, Biochemistry.

Characterization and inactivation of an agmatine deiminase from Helicobacter pylori.

L. Lebioda, P. Thompson, B. Knuckley, 2010, Bioorganic chemistry.

Prefrontal control of trace versus delay eyeblink conditioning: role of the unconditioned stimulus in rabbits (Oryctolagus cuniculus).

B. Oswald, D. Powell, B. Knuckley, 2006, Behavioral neuroscience.

Ibotenic acid lesions to ventrolateral thalamic nuclei disrupts trace and delay eyeblink conditioning in rabbits

B. Oswald, S. Maddox, D. Powell, 2007, Behavioural Brain Research.

Prefrontal control of trace eyeblink conditioning in rabbits (Oryctolagus cuniculus) II: Effects of type of unconditioned stimulus (airpuff vs. periorbital shock) and unconditioned stimulus intensity

B. Oswald, D. Powell, B. Knuckley, 2009, Physiology & Behavior.

Galantamine facilitates acquisition of a trace-conditioned eyeblink response in healthy, young rabbits.

B. Simon, D. Powell, B. Knuckley, 2004, Learning & memory.

Development of a Plate-Based Screening Assay to Investigate the Substrate Specificity of the PRMT Family of Enzymes.

B. Knuckley, Min Wang, Andrew Salsburg, 2015, ACS Combinatorial Science.

Mechanistic studies of the agmatine deiminase from Listeria monocytogenes

C. A. Soares, B. Knuckley, 2016, Biochemical Journal.

Development of a clickable activity-based protein profiling (ABPP) probe for agmatine deiminases.

B. Knuckley, Corey P. Causey, T. Ellis, 2015, Bioorganic & medicinal chemistry.

Design, synthesis, and in vitro evaluation of an activity-based protein profiling (ABPP) probe targeting agmatine deiminases.

B. Knuckley, Corey P. Causey, S. O'Connor, 2014, Bioorganic & medicinal chemistry.

A fluopol-ABPP HTS assay to identify PAD inhibitors.

Steven J Brown, B. Cravatt, P. Thompson, 2010, Chemical communications.

A fluopol-ABPP HTS assay to identify PAD inhibitors.

Steven J Brown, B. Cravatt, P. Thompson, 2010, Chemical communications.