I. Vorberg

发表

DNA Aptamers That Bind to PrPC and Not PrpSc Show Sequence and Structure Specificity

Ping Wang, S. Sreevatsan, Shu G. Chen, 2006, Experimental biology and medicine.

Endogenous retroviruses promote prion-like spreading of proteopathic seeds

S. Müller, S. Lichtenthaler, I. Vorberg, 2022, bioRxiv.

Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions

F. Rousseau, Manuela Neumann, S. Müller, 2021, Nature communications.

Identification of possible animal origins of prion disease in human beings

I. Vorberg, S. Priola, 2004, The Lancet.

Entropic Bristles Tune the Seeding Efficiency of Prion-Nucleating Fragments

Nikolaos N. Louros, F. Rousseau, R. Gallardo, 2020, Cell reports.

All the Same? The Secret Life of Prion Strains within Their Target Cells

I. Vorberg, 2019, Viruses.

Endocytosis of Prion Protein Is Required for ERK1/2 Signaling Induced by Stress-Inducible Protein 1

Fabiana A. Caetano, R. Linden, G. Hajj, 2008, The Journal of Neuroscience.

The yeast Sup35NM domain propagates as a prion in mammalian cells

E. Kremmer, R. Wickner, A. Hofmann, 2009, Proceedings of the National Academy of Sciences.

Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance

M. Schölling, S. Lichtenthaler, I. Vorberg, 2018, Molecular and Cellular Biology.

Viruses in neurodegenerative diseases: More than just suspects in crimes

P. Leblanc, I. Vorberg, 2022, PLoS pathogens.

Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions

F. Rousseau, Manuela Neumann, S. Müller, 2020, Nature Communications.

Prions on the run: How extracellular vesicles serve as delivery vehicles for self-templating protein aggregates

I. Vorberg, Shu Liu, André Hossinger, 2017, Prion.

Deletion of (cid:2) -Strand and (cid:3) -Helix Secondary Structure in Normal Prion Protein Inhibits Formation of Its Protease-Resistant Isoform

I. Vorberg, S. Priola, Kaman Chan, 2001 .

Editorial overview: Prion disease: From drug discovery tools to clinical trials.

R. Chiesa, I. Vorberg, 2019, Current opinion in pharmacology.

Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease.

C. Dieterich, E. Wanker, G. Dittmar, 2019, Journal of molecular biology.

Deregulated Spl Mechanism of R in Huntington ' s

C. Dieterich, E. Wanker, G. Dittmar, 2019 .

Endoplasmic Reticulum Stress Induces Myostatin High Molecular Weight Aggregates and Impairs Mature Myostatin Secretion

I. Vorberg, J. Reimann, Philip Denner, 2018, Molecular Neurobiology.

Inhibition of cholesterol recycling impairs cellular PrPSc propagation

H. Schätzl, I. Vorberg, G. Lutzny, 2009, Cellular and Molecular Life Sciences.

Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils

L. Andreas, M. Zweckstetter, I. Vorberg, 2021, Nature Communications.

Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents.

I. Vorberg, S. Priola, B. Story, 2004, The Journal of infectious diseases.

Prion infection influences murine endogenous retrovirus expression in neuronal cells.

A. Stengel, H. Schätzl, A. Greenwood, 2006, Biochemical and biophysical research communications.

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias

I. Ferrer, I. Zerr, R. Sánchez-Valle, 2017, Molecular Neurodegeneration.

Prion-like propagation of cytosolic protein aggregates

H. Schätzl, I. Vorberg, C. Krammer, 2009, Prion.

Prion protein/protein interactions: fusion with yeast Sup35p‐NM modulates cytosolic PrP aggregation in mammalian cells

E. Kremmer, T. Scheibel, H. Schätzl, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo

P. Veranič, L. Gaedtke, Iva Hafner-Bratkovič, 2011, PloS one.

Globular Domain of the Prion Protein Needs to Be Unlocked by Domain Swapping to Support Prion Protein Conversion*

A. Aguzzi, C. Julius, P. Pristovsek, 2011, The Journal of Biological Chemistry.

Tetracysteine‐tagged prion protein allows discrimination between the native and converted forms

P. Veranič, Iva Hafner-Bratkovič, R. Jerala, 2010, The FEBS journal.

Acute cellular uptake of abnormal prion protein is cell type and scrapie-strain independent.

D. Harris, I. Vorberg, S. Priola, 2008, Virology.

Scrapie Infection of Prion Protein-deficient Cell Line upon Ectopic Expression of Mutant Prion Proteins*

T. Onodera, M. Groschup, H. Schätzl, 2007, Journal of Biological Chemistry.

Multiple Amino Acid Residues within the Rabbit Prion Protein Inhibit Formation of Its Abnormal Isoform

M. Groschup, E. Pfaff, I. Vorberg, 2003, Journal of Virology.

Extracellular Vesicle Separation Techniques Impact Results from Human Blood Samples: Considerations for Diagnostic Applications

C. Coch, U. Völker, G. Hartmann, 2021, International journal of molecular sciences.

Species barriers in prion diseases--brief review.

I. Vorberg, S. Priola, R. Moore, 2005, Archives of virology. Supplementum.

Prion-induced Activation of Cholesterogenic Gene Expression by Srebp2 in Neuronal Cells*

J. Beckers, G. Hajj, S. Brodesser, 2009, The Journal of Biological Chemistry.

Life cycle of cytosolic prions

I. Vorberg, J. Hofmann, 2013, Prion.

Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells

G. Tartaglia, V. Arndt, S. Müller, 2019, Life Science Alliance.

Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones

H. Blum, E. Kremmer, B. Audit, 2021, eLife.

Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis

E. Wanker, G. Dittmar, Alexander Buntru, 2018, Cell Death Discovery.

A novel epitope for the specific detection of exogenous prion proteins in transgenic mice and transfected murine cell lines.

A. Buschmann, M. Groschup, A. Saalmüller, 1999, Virology.

Experimental models to study prion disease pathogenesis and identify potential therapeutic compounds.

R. Chiesa, I. Vorberg, 2019, Current opinion in pharmacology.

Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR

G. Hajj, V. Martins, B. A. Castilho, 2010, Proceedings of the National Academy of Sciences.

Propagation and Dissemination Strategies of Transmissible Spongiform Encephalopathy Agents in Mammalian Cells

I. Vorberg, S. Heumüller, André Hossinger, 2022, International journal of molecular sciences.

Cellular Aspects of Prion Replication In Vitro

I. Vorberg, J. Hofmann, A. Grassmann, 2013, Viruses.

Mammalian amyloidogenic proteins promote prion nucleation in yeast

Y. Chernoff, I. Vorberg, Pavithra Chandramowlishwaran, 2018, The Journal of Biological Chemistry.

Proteasomal Dysfunction and Endoplasmic Reticulum Stress Enhance Trafficking of Prion Protein Aggregates through the Secretory Pathway and Increase Accumulation of Pathologic Prion Protein*

M. Groschup, H. Schätzl, I. Vorberg, 2011, The Journal of Biological Chemistry.

The Novel Sorting Nexin SNX33 Interferes with Cellular PrPSc Formation by Modulation of PrPc Shedding

H. Kretzschmar, M. Groschup, H. Schätzl, 2008, Traffic.

Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells.

Johannes Beckers, Marion Horsch, A. Stengel, 2005, Journal of molecular biology.

Acute Formation of Protease-resistant Prion Protein Does Not Always Lead to Persistent Scrapie Infection in Vitro*

I. Vorberg, S. Priola, A. Raines, 2004, Journal of Biological Chemistry.

The use of monoclonal antibody epitopes for tagging PrP in conversion experiments.

M. Groschup, E. Pfaff, I. Vorberg, 2000, Archives of virology. Supplementum.

Molecular aspects of disease pathogenesis in the transmissible spongiform encephalopathies.

I. Vorberg, S. Priola, 2004, Methods in molecular biology.

Molecular aspects of disease pathogenesis in the transmissible spongiform encephalopathies

I. Vorberg, S. Priola, 2006, Molecular biotechnology.

Deletion of β-Strand and α-Helix Secondary Structure in Normal Prion Protein Inhibits Formation of Its Protease-Resistant Isoform

I. Vorberg, S. Priola, Kaman Chan, 2001, Journal of Virology.

Prion strains depend on different endocytic routes for productive infection

M. Groschup, H. Schätzl, I. Vorberg, 2017, Scientific Reports.

Prion-induced and spontaneous formation of transmissible toxicity in PrP transgenic Drosophila.

O. Andréoletti, I. Vorberg, R. Bujdoso, 2014, The Biochemical journal.

Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins

I. Vorberg, S. Krauß, 2013, International journal of cell biology.

Creutzfeldt-Jakob disease and mad cows: lessons learnt from yeast cells.

V. Arndt, I. Vorberg, J. Hofmann, 2012, Swiss medical weekly.

Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles

I. Vorberg, J. Hofmann, Philip Denner, 2016, mBio.

Dynamic interactions of Sup35p and PrP prion protein domains modulate aggregate nucleation and seeding

E. Kremmer, H. Schätzl, I. Vorberg, 2008, Prion.

Reverse engineering synthetic antiviral amyloids

Nikolaos N. Louros, G. Bormans, H. Wilkinson, 2020, Nature Communications.

Reverse engineering synthetic antiviral amyloids

Frederic Rousseau, Rodrigo Gallardo, Guy Bormans, 2020, Nature Communications.

Intercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells

I. Vorberg, María Moreno-del Álamo, R. Giraldo, 2020, mBio.

Genetic human prion disease modelled in PrP transgenic Drosophila

W. Jackson, I. Vorberg, R. Bujdoso, 2017, The Biochemical journal.

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie

I. Vorberg, V. Sim, Valerie L. Sim, 2015, Front. Neurosci..

Molecular Basis of Scrapie Strain Glycoform Variation*

I. Vorberg, S. Priola, 2002, The Journal of Biological Chemistry.

Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis

E. Wanker, G. Dittmar, Alexander Buntru, 2018, Cell Death Discovery.

Cell-to-cell propagation of infectious cytosolic protein aggregates

T. Scheibel, H. Schätzl, S. Lichtenthaler, 2013, Proceedings of the National Academy of Sciences.

Intercellular transmission of a bacterial cytotoxic prion-like protein in mammalian cells

I. Vorberg, R. Giraldo, V. de los Ríos, 2019, bioRxiv.

Reactivated endogenous retroviruses promote protein aggregate spreading

S. Müller, S. Lichtenthaler, I. Vorberg, 2023, Nature communications.

Defining the Cellular Interactome of Disease-Linked Proteins in Neurodegeneration

V. Arndt, I. Vorberg, 2012 .

Modulation of Glycosaminoglycans Affects PrPSc Metabolism but Does Not Block PrPSc Uptake

M. Groschup, H. Schätzl, I. Vorberg, 2015, Journal of Virology.

Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease.

C. Dieterich, E. Wanker, G. Dittmar, 2019, Journal of molecular biology.