A. Tups

发表

Leptin indirectly regulates gonadotropin-releasing hormone neuronal function.

C. Kemp, Xinhuai Liu, A. Herbison, 2009, Endocrinology.

Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance

C. Culmsee, L. M. Williams, C. Koch, 2015, Diabetes.

Hyperleptinemia as a contributing factor for the impairment of glucose intolerance in obesity

A. Tups, T. Lutz, D. Pretz, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Photoperiodic and Diurnal Regulation of WNT Signaling in the Arcuate Nucleus of the Female Djungarian Hamster, Phodopus sungorus.

G. Helfer, A. Tups, J. Benzler, 2016, Endocrinology.

Hypothalamic glycogen synthase kinase 3β has a central role in the regulation of food intake and glucose metabolism.

M. Schwartz, P. Shepherd, D. Grattan, 2012, The Biochemical journal.

Leptin regulates glucose homeostasis via the canonical WNT pathway

P. Shepherd, J. Horsfield, D. Grattan, 2021, bioRxiv.

“Insulin-like” effects of palmitate compromise insulin signalling in hypothalamic neurons

A. Tups, P. Heyward, J. Benzler, 2019, Journal of Comparative Physiology B.

“Insulin-Like” Effects of Palmitate Might Contribute to the Development of Insulin Resistance in Hypothalamic Neurons

A. Tups, P. Heyward, J. Benzler, 2018 .

Central adiponectin acutely improves glucose tolerance in male mice.

D. Grattan, L. M. Williams, C. Koch, 2014, Endocrinology.

The dietary flavonoids naringenin and quercetin acutely impair glucose metabolism in rodents possibly via inhibition of hypothalamic insulin signalling

G. Heldmaier, N. Hoggard, C. Koch, 2012, British Journal of Nutrition.

Acute Inhibition of Central c‐Jun N‐terminal Kinase Restores Hypothalamic Insulin Signalling and Alleviates Glucose Intolerance in Diabetic Mice

A. Tups, K. Legler, M. Krüger, 2013, Journal of neuroendocrinology.

Temporal and regional onset of leptin resistance in diet‐induced obese mice

D. Grattan, A. Tups, M. Rizwan, 2017, Journal of neuroendocrinology.

High‐Fat Diet Induces Leptin Resistance in Leptin‐Deficient Mice

L. M. Williams, C. Koch, A. Tups, 2014, Journal of neuroendocrinology.

Effect of central and peripheral leucine on energy metabolism in the Djungarian hamster (Phodopus sungorus)

C. Koch, A. Tups, Manon Krüger, 2012, Journal of Comparative Physiology B.

Photoperiodic regulation of insulin receptor mRNA and intracellular insulin signaling in the arcuate nucleus of the Siberian hamster, Phodopus sungorus.

P. Barrett, M. Klingenspor, A. Tups, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Photoperiodic regulation of satiety mediating neuropeptides in the brainstem of the seasonal Siberian hamster (Phodopus sungorus)

G. Heldmaier, M. Klingenspor, A. Tups, 2009, Journal of Comparative Physiology A.

Seasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein

P. Barrett, M. Klingenspor, J. Schachtner, 2012, Journal of Comparative Physiology B.

Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodopus sungorus, is reflected in arcuate nucleus SOCS-3 (suppressor of cytokine signaling) gene expression.

M. Klingenspor, K. Moar, A. Tups, 2004, Endocrinology.

Circulating Ghrelin Levels and Central Ghrelin Receptor Expression are Elevated in Response to Food Deprivation in a Seasonal Mammal (Phodopus sungorus)

M. Klingenspor, R. Khorooshi, A. Tups, 2004, Journal of neuroendocrinology.

Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice.

H. Coleman, H. Parkington, Z. Andrews, 2014, Endocrinology.

Proteomics reveals that a high-fat diet induces rapid changes in hypothalamic proteins related to neuronal damage and inflammation

F. Nicol, N. Hoggard, L. M. Williams, 2011, Proceedings of the Nutrition Society.

Overexpression of suppressor of cytokine signaling 3 in the arcuate nucleus of juvenile Phodopus sungorus alters seasonal body weight changes

C. Culmsee, P. Barrett, A. Tups, 2013, Journal of Comparative Physiology B.

“Insulin-like” effects of palmitate compromise insulin signalling in hypothalamic neurons

A. Tups, P. Heyward, J. Benzler, 2019, Journal of Comparative Physiology B.

Physiological Models of Leptin Resistance

A. Tups, 2009, Journal of neuroendocrinology.

The Suppressor of Cytokine Signalling 3, SOCS3, may be One Critical Modulator of Seasonal Body Weight Changes in the Siberian Hamster, Phodopus sungorus

P. Barrett, M. Klingenspor, A. Tups, 2006, Journal of neuroendocrinology.

Neuropeptides and anticipatory changes in behaviour and physiology: seasonal body weight regulation in the Siberian hamster.

A. Tups, J. Mercer, 2003, European journal of pharmacology.

Altered Expression of SOCS3 in the Hypothalamic Arcuate Nucleus during Seasonal Body Mass Changes in the Field Vole, Microtus agrestis

J. Speakman, P. Morgan, A. Ross, 2007, Journal of neuroendocrinology.

SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice

C. Mayer, H. Roche, C. Diéguez, 2018, Genes & Nutrition.

Hypothalamic leptin sensitivity and health benefits of time‐restricted feeding are dependent on the time of day in male mice

A. Tups, M. Rizwan, Alisa Boucsein, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity

M. Schwartz, P. Shepherd, D. Grattan, 2010, The Journal of Neuroscience.

Loss of Hypothalamic Response to Leptin During Pregnancy Associated with Development of Melanocortin Resistance

D. Grattan, R. A. Augustine, A. Tups, 2009, Journal of neuroendocrinology.

Central signalling cross‐talk between insulin and leptin in glucose and energy homeostasis

A. Tups, Alisa Boucsein, Kaj Kamstra, 2021, Journal of neuroendocrinology.

Central Regulation of Glucose Homeostasis.

L. M. Williams, A. Tups, D. Sergi, 2017, Comprehensive Physiology.

Phenotypic Characterization of miR-92a−/− Mice Reveals an Important Function of miR-92a in Skeletal Development

R. Brandes, A. Zeiher, S. Dimmeler, 2014, PloS one.

Hypothalamic Wnt Signalling and its Role in Energy Balance Regulation

G. Helfer, A. Tups, 2016, Journal of neuroendocrinology.

Both p110α and p110β Isoforms of Phosphatidylinositol 3‐OH‐Kinase are Required for Insulin Signalling in the Hypothalamus

P. Shepherd, D. Grattan, R. A. Augustine, 2010, Journal of neuroendocrinology.

Feeding and glucagon‐like peptide‐1 receptor activation stabilise β‐catenin in specific hypothalamic nuclei in male rats

P. Shepherd, D. Grattan, A. Tups, 2018, Journal of neuroendocrinology.

The Development of Diet-Induced Obesity and Glucose Intolerance in C57Bl/6 Mice on a High-Fat Diet Consists of Distinct Phases

W. Rees, S. Gray, N. Hoggard, 2014, PloS one.

A New Zealand green-lipped mussel oil-enriched high-fat diet exhibits beneficial effects on body weight and metabolism in mice

A. Tups, M. Rizwan, Aline Loehfelm, 2020, British Journal of Nutrition.

Molecular and Neuroendocrine Determinants of Seasonal Body Weight Regulation

A. Tups, 2005 .

Discovery of Leptin and its Catabolic and Glucose-Lowering Action In 1994

L. M. Williams, A. Tups, D. Sergi, 2017 .

Obesity pharmacotherapy: incretin action in the central nervous system.

D. Hay, A. Tups, G. Boer, 2022, Trends in pharmacological sciences.

Effect of central and peripheral leucine on energy metabolism in the Djungarian hamster (Phodopus sungorus)

C. Koch, A. Tups, Manon Krüger, 2013, Journal of Comparative Physiology B.

Seasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein

P. Barrett, M. Klingenspor, J. Schachtner, 2012, Journal of Comparative Physiology B.

Chronic light cycle-disruption alters central insulin and leptin signalling as well as metabolic markers in male mice.

D. Grattan, A. Tups, M. Rizwan, 2019, Endocrinology.

Hypothalamic WNT signalling is impaired during obesity and reinstated by leptin treatment in male mice.

P. Shepherd, Z. Andrews, D. Grattan, 2013, Endocrinology.

Timing Matters: Circadian Effects on Energy Homeostasis and Alzheimer’s Disease

A. Tups, D. Pretz, Alisa Boucsein, 2019, Trends in Endocrinology & Metabolism.

Acyl ghrelin acts in the brain to control liver function and peripheral glucose homeostasis in male mice.

Z. Andrews, S. Lockie, Qunli Wu, 2015, Endocrinology.

Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish

J. Horsfield, D. Grattan, A. Tups, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Docosahexaenoic acid prevents palmitate‐induced insulin‐dependent impairments of neuronal health

Joanna M. Williams, A. Tups, Alisa Boucsein, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

PC1/3 and PC2 Gene Expression and Post‐Translational Endoproteolytic Pro‐Opiomelanocortin Processing is Regulated by Photoperiod in the Seasonal Siberian Hamster (Phodopus sungorus)

P. Barrett, M. Klingenspor, J. Rozman, 2006, Journal of neuroendocrinology.

Dietary wheat gluten induces astro‐ and microgliosis in the hypothalamus of male mice

A. Tups, M. Rizwan, Kaj Kamstra, 2023, Journal of neuroendocrinology.

Acute Inhibition of Central c‐Jun N‐terminal Kinase Restores Hypothalamic Insulin Signalling and Alleviates Glucose Intolerance in Diabetic Mice

A. Tups, G. Ganjam, S. Stöhr, 2013, Journal of neuroendocrinology.

Both p110α and p110β Isoforms of Phosphatidylinositol 3‐OH‐Kinase are Required for Insulin Signalling in the Hypothalamus

P. Shepherd, D. Grattan, R. A. Augustine, 2010, Journal of neuroendocrinology.