T. Druck

C. Croce, K. Huebner, Z. Siprashvili, 1998, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Structure of the human receptor tyrosine phosphatase gamma gene (PTPRG) and relation to the familial RCC t(3;8) chromosome translocation.

K. Huebner, D. Moir, J. Lasota, 1996, Genomics.

Detailed genetic and physical map of the 3p chromosome region surrounding the familial renal cell carcinoma chromosome translocation, t(3;8)(p14.2;q24.1).

F. Latif, G. Barnea, K. Tory, 1993, Cancer research.

Wwox Suppresses Prostate Cancer Cell Growth through Modulation of ErbB2-Mediated Androgen Receptor Signaling

D. Iliopoulos, S. Volinia, S. Costinean, 2007, Molecular Cancer Research.

The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32.

C. Croce, K. Huebner, M. Kraus, 1994, Oncogene.

Chromosome locations of the MYB related genes, AMYB and BMYB.

C. Croce, K. Huebner, B. Calabretta, 1991, Cancer research.

Biological Functions of Mammalian Nit1, the Counterpart of the Invertebrate NitFhit Rosetta Stone Protein, a Possible Tumor Suppressor*

D. Iliopoulos, Y. Pekarsky, C. Croce, 2006, Journal of Biological Chemistry.

Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.

J. Sun, C. Croce, K. Huebner, 2011, Carcinogenesis.

Effect of zinc supplementation on N -nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deﬁcient mouse strains

J. Sun, C. Croce, K. Huebner, 2011 .

Cloning and chromosomal localization of a human endothelin ETA receptor.

K. Huebner, T. Druck, R. Kris, 1991, Biochemical and biophysical research communications.

Positions of chromosome 3p14.2 fragile sites (FRA3B) within the FHIT gene.

C. Croce, K. Huebner, D. Zimonjic, 1997, Cancer research.

Characterization of human bone marrow‐derived closed circular DNA clones

C. Croce, K. Huebner, J. Lasota, 1993, Genes, chromosomes & cancer.

The leukemia inhibitory factor receptor (LIFR) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13.

K. Huebner, N. Copeland, D. Gilbert, 1993, Genomics.

Molecular cloning of the interleukin-1 beta converting enzyme.

C. March, D. Cerretti, C. Kozlosky, 1992, Science.

Characterization of the Mammalian YAP (Yes-associated Protein) Gene and Its Role in Defining a Novel Protein Module, the WW Domain (*)

P. Bork, M. Negrini, K. Huebner, 1995, The Journal of Biological Chemistry.

Evolutionary conservation of the EPS8 gene and its mapping to human chromosome 12q23-q24.

C. Croce, K. Huebner, M. Kraus, 1994, Oncogene.

Assignment of the gene (EPLG2) encoding a high-affinity binding protein for the receptor tyrosine kinase elk to a 200-kilobasepair region in human chromosome Xq12.

L. Shaffer, A. Monaco, J. Belmont, 1995, Genomics.

Chromosome locations of genes encoding human signal transduction adapter proteins, Nck (NCK), Shc (SHC1), and Grb2 (GRB2).

K. Huebner, L. Lanfrancone, S. Park, 1994, Genomics.

The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system.

O. Silvennoinen, A. Honegger, G. Barnea, 1993, The Journal of biological chemistry.

Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells

C. Croce, R. Aqeilan, T. Palumbo, 2019, Cell Death & Disease.

Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.

Y. Pekarsky, C. Croce, M. Campiglio, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Wwox–Brca1 interaction: role in DNA repair pathway choice

N. Heerema, K. Huebner, J. Parvin, 2016, Oncogene.

Common regions of deletion in chromosome regions 3p12 and 3p14.2 in primary clear cell renal carcinomas.

K. Huebner, J. Lubiński, P. McCue, 1994, Cancer research.

Retroposition in a family of carcinoma-associated antigen genes

K. Huebner, B. A. Seng, A. Linnenbach, 1993, Molecular and cellular biology.

Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion.

C. Croce, H. Ishii, K. Huebner, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer.

C. Croce, N. Chiorazzi, F. Bullrich, 1995, Cancer research.

Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax

C. Croce, K. Huebner, H. Alder, 1997, Oncogene.

Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.

C. Croce, K. Mimori, K. Huebner, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Muir-Torre-like syndrome in Fhit-deficient mice.

C. Croce, R. Mancini, K. Huebner, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Hits, Fhits and Nits: beyond enzymatic function.

Jin Sun, Hidetaka Shibata, K. Huebner, 2011, Advances in enzyme regulation.

The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B.

C. Croce, K. Huebner, Z. Siprashvili, 1997, Biochimica et biophysica acta.

Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.

K. Huebner, F. Bullrich, K. Gripp, 1995, Cytogenetics and cell genetics.

Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit

W. Miller, C. Croce, K. Mimori, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Structure and expression of the human FHIT gene in normal and tumor cells.

C. Croce, M. Negrini, R. Baffa, 1997, Cancer research.

Cloning of cDNAs encoding the human BAG1 protein and localization of the human BAG1 gene to chromosome 9p12.

J. Inazawa, K. Huebner, John Calvin Reed, 1996, Genomics.

A role for the WWOX gene in prostate cancer.

D. Iliopoulos, C. Morrison, C. Croce, 2006, Cancer research.

Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer

Dimitrios Iliopoulos, D. Iliopoulos, J. Palazzo, 2005, Oncogene.

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.

Y. Pekarsky, C. Croce, A. Palamarchuk, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.

C. Croce, H. Ishii, K. Huebner, 2003, Molecular cancer research : MCR.

The FHIT gene at 3p14.2 is abnormal in breast carcinomas.

C. Croce, M. Negrini, R. Baffa, 1996, Cancer research.

Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.

M. Rugge, C. Croce, M. Negrini, 1996, Cancer research.

The BAX gene maps to the glioma candidate region at 19q13.3, but is not altered in human gliomas.

D. Louis, H. Mohrenweiser, K. Huebner, 1996, Cancer genetics and cytogenetics.

Roles of FHIT and WWOX fragile genes in cancer.

D. Iliopoulos, K. Huebner, Shuang-yin Han, 2006, Cancer letters.

Influence of a nonfragile FHIT transgene on murine tumor susceptibility

C. Croce, R. Mancini, K. Huebner, 2007, Cytogenetic and Genome Research.

The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells.

Y. Pekarsky, C. Croce, K. Huebner, 1998, Cancer research.

Identification of Fhit as a post-transcriptional effector of Thymidine Kinase 1 expression.

K. Huebner, R. Bundschuh, T. Druck, 2017, Biochimica et biophysica acta. Gene regulatory mechanisms.

Fhit Deficiency-Induced Global Genome Instability Promotes Mutation and Clonal Expansion

J. Sun, K. Huebner, V. Jin, 2013, PloS one.

Fhit modulates the DNA damage checkpoint response.

C. Croce, K. Mimori, H. Ishii, 2006, Cancer research.

Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer.

E. Rosato, C. Croce, H. Ishii, 2001, Cancer research.

Cloning, Characterization, and Chromosomal Localization of a Human 5‐HT6 Serotonin Receptor

D. Sibley, B. Roth, K. Huebner, 1996, Journal of neurochemistry.

Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation

K. Huebner, N. Zanesi, X. Pan, 2016, Cancer medicine.

Fhit and Wwox loss-associated genome instability: A genome caretaker one-two punch.

K. Huebner, B. Batar, T. Druck, 2017, Advances in biological regulation.

The human homologue of the retroviral oncogene qin maps to chromosome 14q13.

C. Croce, K. Huebner, P. Vogt, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Cloning and characterization of two members of the vertebrate Dlx gene family.

M. D'Esposito, M. Gulisano, A. Simeone, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a conserved family of Meis1-related homeobox genes.

K. Huebner, J. Moskow, I. Daar, 1997, Genome research.

Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.

C. Croce, K. Huebner, H. Thiesen, 1991, American journal of human genetics.

Fhit-deficient hematopoietic stem cells survive hydroquinone exposure carrying precancerous changes.

K. Mimori, H. Ishii, K. Huebner, 2008, Cancer research.

Interaction of Wwox with Brca1 and associated complex proteins prevents premature resection at double-strand breaks and aberrant homologous recombination.

K. Huebner, T. Druck, Dongju Park, 2021, DNA repair.

Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family.

K. Huebner, B. Calabretta, D. Perrotti, 1997, Cancer research.

Candidate tumor suppressor genes at FRA7G are coamplified with MET and do not suppress malignancy in a gastric cancer.

K. Huebner, Shuang-yin Han, T. Druck, 2003, Genomics.

Absence or reduction of Fhit expression in most clear cell renal carcinomas.

Y. Pekarsky, K. Huebner, J. Lubiński, 1998, Cancer research.

Inhibition of Breast Cancer Cell Growth In vitro and In vivo: Effect of Restoration of Wwox Expression

D. Iliopoulos, M. Fabbri, K. Huebner, 2007, Clinical Cancer Research.

Inhibitionof Breast Cancer Cell Growth In vitro and In vivo : Effect of Restoration ofWwox Expression

D. Iliopoulos, M. Fabbri, K. Huebner, 2006 .

Complementary DNA cloning of the alternatively expressed endothelial cell glycoprotein Ib beta (GPIb beta) and localization of the GPIb beta gene to chromosome 22.

K. Huebner, S. Shapiro, D. Essex, 1994, The Journal of clinical investigation.

Exome‐wide single‐base substitutions in tissues and derived cell lines of the constitutive Fhit knockout mouse

K. Huebner, Carolyn Paisie, T. Druck, 2016, Cancer science.

FHITness and cancer.

K. Huebner, L. Berk, T. Druck, 1998, Oncology research.

Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential

D. Iliopoulos, Y. Pekarsky, C. Croce, 2006, Oncogene.

Chromosome locations of human EMX and OTX genes.

A. Simeone, D. Acampora, K. Huebner, 1994, Genomics.

Phospholipase C gamma-2 (Plcg2) and phospholipase C gamma-1 (Plcg1) map to distinct regions in the human and mouse genomes.

K. Huebner, L. Siracusa, J. Knopf, 1995, Genomics.

Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells

C. Croce, R. Aqeilan, T. Palumbo, 2019, Cell Death & Disease.

Nit1 and Fhit tumor suppressor activities are additive

J. Sun, W. Frankel, K. Huebner, 2009, Journal of cellular biochemistry.

PTPN13, a fas-associated protein tyrosine phosphatase, is located on the long arm of chromosome 4 at band q21.3.

J. Inazawa, K. Huebner, John Calvin Reed, 1996, Genomics.

Fhit loss‐associated initiation and progression of neoplasia in vitro

K. Huebner, K. L. La Perle, B. Batar, 2016, Cancer science.

The DIRC1 gene at chromosome 2q33 spans a familial RCC-associated t(2;3)(q33;q21) chromosome translocation

K. Huebner, J. Lubiński, L. Wyrwicz, 2001, Journal of Human Genetics.

Characterization of a familial RCC-associated t(2;3)(q33;q21) chromosome translocation

K. Huebner, J. Lubiński, D. Zimonjic, 2001, Journal of Human Genetics.

Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP.

K. Huebner, J. Keen, S. Park, 1995, Genomics.

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.

Y. Pekarsky, C. Croce, R. Aqeilan, 2004, Proceedings of the National Academy of Sciences of the United States of America.

The ubiquitous ‘cancer mutational signature’ 5 occurs specifically in cancers with deleted FHIT alleles

S. Volinia, K. Huebner, Carolyn Paisie, 2017, Oncotarget.