S. Ferguson

发表

C9orf72: At the intersection of lysosome cell biology and neurodegenerative disease

Joseph Amick, S. Ferguson, 2017, Traffic.

Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission

Pietro De Camilli, Andrea Raimondi, Hongying Shen, 2011, Neuron.

Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB

R. Botelho, S. Ferguson, M. Gray, 2016, Current Biology.

Role of dynamin, synaptojanin, and endophilin in podocyte foot processes.

P. De Camilli, S. Ishibe, L. Holzman, 2012, The Journal of clinical investigation.

Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment

S. Ferguson, B. Angarola, 2019, bioRxiv.

Weak Membrane Interactions Allow Rheb to Activate mTORC1 Signaling Without Major Lysosome Enrichment

S. Ferguson, B. Angarola, 2019, bioRxiv.

Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment

S. Ferguson, B. Angarola, 2019, bioRxiv.

WDR41 supports lysosomal response to changes in amino acid availability

A. Tharkeshwar, Joseph Amick, S. Ferguson, 2018, Molecular biology of the cell.

GATOR1-dependent recruitment of FLCN–FNIP to lysosomes coordinates Rag GTPase heterodimer nucleotide status in response to amino acids

S. Ferguson, Jin-Gui Meng, 2018, The Journal of cell biology.

Neuronal lysosomes

S. Ferguson, 2019, Neuroscience Letters.

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane

Hongying Shen, I. Lax, J. Schlessinger, 2012, Proceedings of the National Academy of Sciences.

Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits.

P. De Camilli, Hongying Shen, O. Destaing, 2009, Developmental cell.

Localization of cholinergic innervation in guinea pig heart by immunohistochemistry for high-affinity choline transporters.

R. Blakely, S. Ferguson, C. Ganote, 2004, Cardiovascular research.

Receptor-like role for PQLC2 amino acid transporter in the lysosomal sensing of cationic amino acids

Joseph Amick, S. Ferguson, Gabriel Talaia, 2020, Proceedings of the National Academy of Sciences.

Essential Function of Dynamin in the Invasive Properties and Actin Architecture of v-Src Induced Podosomes/Invadosomes

P. De Camilli, R. Baron, A. Grichine, 2013, PloS one.

Axonal transport and maturation of lysosomes

S. Ferguson, 2018, Current Opinion in Neurobiology.

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes

P. De Camilli, R. Flavell, Matthew M. Staron, 2015, Proceedings of the National Academy of Sciences.

Lysosomes relax in the cellular suburbs

S. Ferguson, S. Gowrishankar, 2016, The Journal of cell biology.

Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death during Mammary Gland Involution Cell death during involution

Dann, J. Wysolmerski, Diana Athonvarangkul, 2022 .

Molecular cloning and characterization of a murine hemicholinium-3-sensitive choline transporter.

R. Blakely, S. Ferguson, S. Apparsundaram, 2001, Biochemical Society transactions.

Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses

L. Looger, P. De Camilli, X. Lou, 2012, Proceedings of the National Academy of Sciences.

Recessive Mutations in AP1B1 Cause Ichthyosis, Deafness, and Photophobia.

R. Lifton, K. Choate, L. Boyden, 2019, American journal of human genetics.

Beyond indigestion: emerging roles for lysosome-based signaling in human disease.

S. Ferguson, 2015, Current opinion in cell biology.

Vesicular Localization and Activity-Dependent Trafficking of Presynaptic Choline Transporters

A. Levey, R. Blakely, C. Heilman, 2003, The Journal of Neuroscience.

Molecular cloning of a human, hemicholinium-3-sensitive choline transporter.

R. Blakely, S. Apparsundaram, A. George, 2000, Biochemical and biophysical research communications.

New Roles for Synaptic Vesicles ? The Choline Transporter Resurfaces :

R. Blakely, S. Ferguson, 2004 .

Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.

Randy D Blakely, A. Levey, R. Blakely, 2003, Molecular pharmacology.

Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system

A. Levey, R. Blakely, E. Mufson, 2003, The Journal of comparative neurology.

The choline transporter resurfaces: new roles for synaptic vesicles?

Randy D Blakely, R. Blakely, S. Ferguson, 2004, Molecular interventions.

Lethal impairment of cholinergic neurotransmission in hemicholinium-3-sensitive choline transporter knockout mice.

J. Tapia, R. Blakely, M. Bazalakova, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Nonoisotopic assay for the presynaptic choline transporter reveals capacity for allosteric modulation of choline uptake.

R. Blakely, Ericka C. Holmstrand, S. Ferguson, 2012, ACS chemical neuroscience.

Regulation of Choline Transporter Surface Expression and Phosphorylation by Protein Kinase C and Protein Phosphatase 1/2A

R. Blakely, S. Apparsundaram, S. Ferguson, 2004, Journal of Pharmacology and Experimental Therapeutics.

Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology

S. Ferguson, Yumei Wu, S. Gowrishankar, 2017, The Journal of cell biology.

The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

A. Ballabio, J. Brugarolas, R. Puertollano, 2018, The EMBO journal.

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

T. Walther, S. Ferguson, Constance S. Petit, 2012, Science Signaling.

A Selective Activity-Dependent Requirement for Dynamin 1 in Synaptic Vesicle Endocytosis

P. De Camilli, G. Miesenböck, M. Wölfel, 2007, Science.

Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning

S. Devireddy, S. Lichtenthaler, S. Ferguson, 2022, Traffic.

Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo

S. Devireddy, S. Ferguson, 2021, The Journal of cell biology.

Surf4 Promotes Endoplasmic Reticulum Exit of the Lysosomal Prosaposin-Progranulin Complex

S. Devireddy, S. Ferguson, 2021, bioRxiv.

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

P. De Camilli, J. Grutzendler, M. Schrag, 2015, Proceedings of the National Academy of Sciences.

Dynamin, a membrane-remodelling GTPase

Pietro De Camilli, P. Camilli, S. Ferguson, 2012, Nature Reviews Molecular Cell Biology.

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors

P. De Camilli, Xinran Liu, Hongying Shen, 2013, Journal of Cell Science.

Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases

S. Ferguson, Constance S. Petit, Agnes Roczniak-Ferguson, 2013, The Journal of cell biology.

Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts

P. De Camilli, R. Baron, H. Saito, 2014, The Journal of cell biology.

Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin

Steven Gygi, Noah Dephoure, Joseph Schlessinger, 2011, Molecular biology of the cell.

Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasis.

L. Philipson, X. Lou, S. Ferguson, 2015, The Journal of clinical investigation.

PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer’s disease

Timothy J. Hohman, D. Bennett, T. Hohman, 2019, bioRxiv.

Prosaposin is a regulator of progranulin levels and oligomerization

Tanya M. Teslovich, G. Abecasis, T. Frayling, 2016, Nature Communications.

Motor neuron-specific overexpression of the presynaptic choline transporter: impact on motor endurance and evoked muscle activity

R. Blakely, A. Peltier, S. Ferguson, 2010, Neuroscience.

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

P. De Camilli, A. Tharkeshwar, G. Shadel, 2021, bioRxiv.

Dynamin 2–dependent endocytosis is required for sustained S1PR1 signaling

P. De Camilli, R. Flavell, S. Ferguson, 2014, The Journal of experimental medicine.

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

P. De Camilli, Xinran Liu, E. O'Toole, 2014, eLife.

Overlapping Role of Dynamin Isoforms in Synaptic Vesicle Endocytosis

E. O'Toole, P. Camilli, V. Cappello, 2011, Neuron.

Cell- and stimulus-dependent heterogeneity of synaptic vesicle endocytic recycling mechanisms revealed by studies of dynamin 1-null neurons

P. De Camilli, E. O'Toole, C. Collesi, 2008, Proceedings of the National Academy of Sciences.

TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism

E. Henske, S. Viswanathan, S. Ferguson, 2021, Nature Communications.

LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia via Transcription Factor E3 Inhibition

S. Ferguson, Narayana Yadavalli, 2022 .

Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.

Paul Beckett, Jonathan Rothberg, J. Rothberg, 2017, Blood.

Nutrient signaling pathways regulate amyloid clearance and synaptic loss in Alzheimer’s disease

R. Nitsch, T. Spires-Jones, P. Schulz, 2020, bioRxiv.

Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay

Robert V Farese, E. Huang, A. Karydas, 2018, Proceedings of the National Academy of Sciences.

Coordination of Rheb lysosomal membrane interactions with mTORC1 activation

S. Ferguson, B. Angarola, 2020, F1000Research.

Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation

S. Schmid, S. Ferguson, R. Ramachandran, 2011, Proceedings of the National Academy of Sciences.

Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis

S. Ferguson, Agnes Roczniak-Ferguson, 2019, Life Science Alliance.

JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton

P. De Camilli, S. Ferguson, N. M. Rafiq, 2020, bioRxiv.

PQLC2 recruits the C9orf72 complex to lysosomes in response to cationic amino acid starvation

A. Tharkeshwar, Joseph Amick, S. Ferguson, 2019, The Journal of cell biology.

PQLC2 signals lysosomal cationic amino acid abundance to the C9orf72 complex

A. Tharkeshwar, Joseph Amick, S. Ferguson, 2019, bioRxiv.

C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling

Joseph Amick, S. Ferguson, Agnes Roczniak-Ferguson, 2016, Molecular biology of the cell.

1 C 9 orf 72 binds SMCR 8 , localizes to lysosomes and regulates mTORC 1 signaling

Joseph Amick, S. Ferguson, Agnes Roczniak-Ferguson, 2016 .

Identi fi cation of apilimod as a fi rst-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma

J. Rothberg, Tian Xu, Meiling Zheng, 2017 .

Selective saturation of slow endocytosis at a giant glutamatergic central synapse lacking dynamin 1

P. De Camilli, X. Lou, S. Ferguson, 2008, Proceedings of the National Academy of Sciences.

LyTS: A Lysosome Localized Complex of TMEM192 and STK11IP

S. Ferguson, B. Angarola, F. Frölich, 2021, bioRxiv.

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons

P. De Camilli, S. Ferguson, N. M. Rafiq, 2020, bioRxiv.

Coordinated Actions of Actin and BAR Proteins Upstream of Dynamin at Endocytic Clathrin-Coated Pits (DOI: 10.1016/j.devcel.2009.11.005)

Hongying Shen, P. Camilli, O. Destaing, 2010 .

Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts

P. De Camilli, T. A. Ryan, S. Ferguson, 2013, eLife.

LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition

S. Ferguson, Narayana Yadavalli, 2023, bioRxiv.

Lysosomes Dare Cells to be Different(iated).

S. Ferguson, Agnes Roczniak-Ferguson, 2019, Cell stem cell.

A lentiviral system for efficient knockdown of proteins in neuronal cultures [version 1; referees: 2 approved]

P. De Camilli, P. McPherson, S. Ferguson, 2017, MNI open research.

Scaled-expansion of the membrane associated cytoskeleton requires conserved kinesin adaptors

S. Yogev, Marc Hammarlund, S. Ferguson, 2022, bioRxiv.

Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death by Activating a TGFβ3/TFEB/STAT3 Pathway Early during Mammary Gland Involution

J. Wysolmerski, Diana Athonvarangkul, S. Ferguson, 2023, bioRxiv.

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

P. De Camilli, W. Sessa, Yunzhou Dong, 2014, Development.

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

P. De Camilli, W. Sessa, Yunzhou Dong, 2014, Journal of Cell Science.

Membrane traffic en route to cancer

S. Ferguson, 2015, Science.

Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses

L. Looger, P. De Camilli, X. Lou, 2012, Proceedings of the National Academy of Sciences.

Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasis.

L. Philipson, X. Lou, S. Ferguson, 2015, The Journal of clinical investigation.

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

P. De Camilli, W. Sessa, Yunzhou Dong, 2014, Development.