A. K. Carmona

A. K. Carmona, N. Bissoli, G. Abreu, 2013, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

ACE activity is modulated by the enzyme α-galactosidase A

C. Nakaie, R. Santos, D. Casarini, 2010, Journal of Molecular Medicine.

High aminopeptidase A activity contributes to blood pressure control in ob/ob mice by AT2 receptor-dependent mechanism.

M. Mori, N. Alenina, C. Nakaie, 2017, American journal of physiology. Heart and circulatory physiology.

Substrate specificity studies of the cysteine peptidases falcipain-2 and falcipain-3 from Plasmodium falciparum and demonstration of their kininogenase activity.

P. Rosenthal, L. Juliano, M. Juliano, 2013, Molecular and biochemical parasitology.

The effect of post-translational modifications on the hemorrhagic activity of snake venom metalloproteinases.

A. K. Carmona, H. Selistre‐de‐Araujo, O. Ramos, 2004, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

The critical interaction of the metallopeptidase PHEX with heparan sulfate proteoglycans.

L. Juliano, M. Juliano, F. D. Nascimento, 2008, The international journal of biochemistry & cell biology.

Sugarcane cystatins: From discovery to biotechnological applications.

A. Schiermeyer, A. Soares-Costa, F. Henrique-Silva, 2020, International journal of biological macromolecules.

Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes

Lionel Urán Landaburu, Fernán Agüero, J. Cazzulo, 2019, PLoS neglected tropical diseases.

Immunochemical and biological characterization of monoclonal antibodies against BaP1, a metalloproteinase from Bothrops asper snake venom.

J. Gutiérrez, A. Rucavado, A. Moura-da-Silva, 2010, Toxicon : official journal of the International Society on Toxinology.

Purification and characterization of angiotensin I‐converting enzymes from mesangial cells in culture

D. Casarini, A. K. Carmona, B. M. Quinto, 1998, Journal of hypertension.

Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides to define substrate specificity of carboxydipeptidases: assays with human cathepsin B.

L. Juliano, M. Juliano, A. K. Carmona, 2004, Analytical biochemistry.

High sucrose intake in rats is associated with increased ACE2 and angiotensin-(1–7) levels in the adipose tissue

M. S. Araujo, M. Dolnikoff, D. Casarini, 2010, Regulatory Peptides.

Carboxydipeptidase activities of recombinant cysteine peptidases. Cruzain of Trypanosoma cruzi and CPB of Leishmania mexicana.

G. H. Coombs, L. Juliano, M. Juliano, 2004, European journal of biochemistry.

Heparin modulation of human plasma kallikrein on different substrates and inhibitors

M. S. Araujo, H. Nader, A. K. Carmona, 2006, Biological chemistry.

Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth

L. Juliano, M. Juliano, T. Paschoalin, 2007, Molecular Cancer.

Cathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblasts

S. Stevanović, M. Bogyo, N. D. Staudt, 2010, Haematologica.

Substrate specificity profiling of M32 metallocarboxypeptidases from Trypanosoma cruzi and Trypanosoma brucei.

L. Juliano, M. Juliano, J. Cazzulo, 2018, Molecular and biochemical parasitology.

Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses

G. Amarante-Mendes, L. Ferreira, A. K. Carmona, 2013, Proceedings of the National Academy of Sciences.

The effect of structural motifs on the ectodomain shedding of human angiotensin-converting enzyme.

E. Sturrock, A. K. Carmona, S. Schwager, 2016, Biochemical and biophysical research communications.

Human tissue kallikreins 3 and 5 can act as plasminogen activator releasing active plasmin.

M. Blaber, L. Juliano, M. Juliano, 2013, Biochemical and Biophysical Research Communications - BBRC.

NPCdc, a synthetic natriuretic peptide, is a substrate to neprilysin and enhances blood pressure-lowering induced by enalapril in 5/6 nephrectomized rats.

A. K. Carmona, R. S. Aires, L. D. Vieira, 2021, Toxicon : official journal of the International Society on Toxinology.

PnPP‐19, a spider toxin peptide, induces peripheral antinociception through opioid and cannabinoid receptors and inhibition of neutral endopeptidase

A. K. Carmona, M. E. Lima, I. Duarte, 2016, British journal of pharmacology.

Human recombinant endopeptidase PHEX has a strict S1' specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein.

L. Juliano, M. Juliano, P. Crine, 2003, The Biochemical journal.

Carbamazepine inhibits angiotensin I-converting enzyme, linking it to the pathogenesis of temporal lobe epilepsy

E. Cavalheiro, G. Gallo, M. Würtele, 2012, Translational Psychiatry.

Tissue-specific renin-angiotensin system in pulmonary lymphangioleiomyomatosis.

V. Ferrans, J. Moss, P. Bruneval, 2006, American journal of respiratory cell and molecular biology.

Peptide inhibitors of angiotensin-I converting enzyme based on angiotensin (1-7) with selectivity for the C-terminal domain.

E. Sturrock, C. Nakaie, G. Spyroulias, 2022, Bioorganic chemistry.

Involvement of heparan sulfate proteoglycans in cellular uptake of high molecular weight kininogen

M. S. Araujo, F. D. Nascimento, Y. M. Coulson-Thomas, 2009, Biological chemistry.

N-domain angiotensin-converting enzyme isoform expression in tissues of Wistar and spontaneously hypertensive rats

J. Krieger, F. A. Ronchi, D. Casarini, 2005, Journal of hypertension.

Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme.

L. Juliano, M. Juliano, A. K. Carmona, 2000, Biochemistry.

Purification and characterization of a neutral endopeptidase‐like enzyme from human urine

M. Juliano, D. Casarini, A. K. Carmona, 1998, Journal of hypertension.

Exposure of luminal membranes of LLC-PK1 cells to ANG II induces dimerization of AT1/AT2 receptors to activate SERCA and to promote Ca2+ mobilization.

C. Costa-Neto, A. K. Carmona, A. Vieyra, 2012, American journal of physiology. Renal physiology.

Expression of the selectable marker gene bsrm in BALB/MK cells induces apoptosis by overproduction of hydrogen peroxide.

J. Belizário, R. Chammas, A. K. Carmona, 2007, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Expression and localization of N-domain ANG I-converting enzymes in mesangial cells in culture from spontaneously hypertensive rats.

R. Mortara, D. Casarini, J. Pesquero, 2006, American journal of physiology. Renal physiology.

spontaneously hypertensive rats from I-converting enzymes in mesangial cells in culture Expression and localization of N-domain ANG

R. Mortara, D. Casarini, A. K. Carmona, 2006 .

Expression and localization of N-domain angiotensin I-converting enzymes (ACE) in mesangial cells in culture from spontaneously hypertensive rats (SHR).

R. Mortara, J. Pesquero, A. K. Carmona, 2005 .

Angiotensin I-converting enzyme isoforms (high and low molecular weight) in urine of premature and full-term infants.

D. Casarini, A. K. Carmona, G. Del Ben, 2000, Hypertension.

Premature and Full-Term Infants Converting Enzyme Isoforms ( High and Low Molecular Weight ) in Urine of −

D. Casarini, A. K. Carmona, Print, 2000 .

Plasma prekallikrein/kallikrein processing by lysosomal cysteine proteases

C. Sampaio, A. K. Carmona, I. Tersariol, 2004, Biological chemistry.

Angiotensin-converting enzyme in pericardial fluid: comparative study with serum activity.

A. K. Carmona, P. A. Bersanetti, R. A. Gomes, 2008, Arquivos brasileiros de cardiologia.

A continuous fluorescent assay for the determination of plasma and tissue angiotensin I-converting enzyme activity.

J. Krieger, L. Juliano, M. Juliano, 2005, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Neprilysin carboxydipeptidase specificity studies and improvement in its detection with fluorescence energy transfer peptides

L. Juliano, M. Juliano, A. K. Carmona, 2007, Biological chemistry.

A possible alternative mechanism of kinin generation in vivo by cathepsin L

L. Juliano, M. S. Araujo, A. K. Carmona, 2005, Biological chemistry.

Inhibitory selectivity of canecystatin: a recombinant cysteine peptidase inhibitor from sugarcane.

A. Soares-Costa, F. Henrique-Silva, A. K. Carmona, 2004, Biochemical and biophysical research communications.

Cathepsin X binds to cell surface heparan sulfate proteoglycans.

L. Juliano, F. D. Nascimento, I. Štefe, 2005, Archives of biochemistry and biophysics.

ANG-(3-4) inhibits renal Na+-ATPase in hypertensive rats through a mechanism that involves dissociation of ANG II receptors, heterodimers, and PKA.

A. K. Carmona, A. Vieyra, L. Lara, 2014, American journal of physiology. Renal physiology.

Role of the kallikrein–kinin system in Ang-(1-7)-induced vasodilation in mesenteric arterioles of Wistar rats studied in vivo–in situ

Z. Fortes, A. K. Carmona, D. Nigro, 2006, Peptides.

Heparin affects the interaction of kininogen on endothelial cells.

K. Shimamoto, M. S. Araujo, H. Nader, 2011, Biochimie.

Corneal angiogenesis modulation by cysteine cathepsins: In vitro and in vivo studies.

J. Chagas, M. Farah, A. K. Carmona, 2015, Experimental eye research.

Characterization of arazyme, an exocellular metalloprotease isolated from Serratia proteamaculans culture medium

L. Juliano, M. Juliano, K. Son, 2005 .

Characterization of arazyme, an exocellular metalloprotease isolated from culture medium

L. Juliano, M. Juliano, K. Son, 2005 .

Cathepsin K inhibitors based on 2-amino-1,3,4-oxadiazole derivatives.

A. A. de Castro, T. Ramalho, A. K. Carmona, 2021, Bioorganic chemistry.

Conformational Properties of Seven Toac-Labeled Angiotensin I Analogues Correlate with Their Muscle Contraction Activity and Their Ability to Act as ACE Substrates

C. Nakaie, S. Schreier, L. Malavolta, 2015, PloS one.

Characterization of a Recombinant Cathepsin B-Like Cysteine Peptidase from Diaphorina citri Kuwayama (Hemiptera: Liviidae): A Putative Target for Control of Citrus Huanglongbing

L. T. Kishi, J. Rosa, W. Hunter, 2015, PloS one.

Recombinant expression, characterization and phylogenetic studies of novels cystatins-like proteins of sweet orange (Citrus sinensis) and clementine (Citrus clementina).

V. Schneider, A. Soares-Costa, F. Henrique-Silva, 2020, International journal of biological macromolecules.

Fungal morphogenesis and virulence.

A. Casadevall, N. Gow, L. Travassos, 2000, Medical mycology.

Exocellular proteolytic activity of Paracoccidioides brasiliensis: cleavage of components associated with the basement membrane.

L. Juliano, L. Travassos, R. Puccia, 2008, Medical mycology.

Characterization of an exocellular serine-thiol proteinase activity in Paracoccidioides brasiliensis.

L. Juliano, L. Travassos, R. Puccia, 1995, The Biochemical journal.

Paracoccidioides brasiliensis induces cytokine secretion in epithelial cells in a protease-activated receptor-dependent (PAR) manner

E. Suzuki, M. Juliano, A. Tanaka, 2016, Medical Microbiology and Immunology.

Leishmanicidal and Immunomodulatory Activities of the Palladacycle Complex DPPE 1.1, a Potential Candidate for Treatment of Cutaneous Leishmaniasis

C. Barbiéri, A. K. Carmona, D. M. Garcia, 2018, Front. Microbiol..

An unexpected inhibitory activity of Kunitz-type serine proteinase inhibitor derived from Boophilus microplus trypsin inhibitor on cathepsin L.

S. D. Sasaki, A. Tanaka, A. K. Carmona, 2006, Biochemical and biophysical research communications.

Biochemical characterization of a cysteine proteinase from Bauhinia forficata leaves and its kininogenase activity

M. Juliano, M. S. Araujo, R. A. Silva-Lucca, 2011 .

Structure of Cruzipain/Cruzain Inhibitors Isolated from Bauhinia bauhinioides Seeds

C. Sampaio, A. K. Carmona, M. H. Cezari, 2001, Biological chemistry.

S3 to S3' subsite specificity of recombinant human cathepsin K and development of selective internally quenched fluorescent substrates.

L. Juliano, M. Juliano, D. Brömme, 2003, The Biochemical journal.

Cathepsin B carboxydipeptidase specificity analysis using internally quenched fluorescent peptides.

L. Juliano, M. Juliano, A. K. Carmona, 2002, The Biochemical journal.

The Candida albicans AAA ATPase homologue of Saccharomyces cerevisiae Rix7p (YLL034c) is essential for proper morphology, biofilm formation and activity of secreted aspartyl proteinases.

M. Briones, A. K. Carmona, A. C. Padovan, 2006, Genetics and molecular research : GMR.

Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X‐linked hypophosphatemia

M. McKee, A. K. Carmona, D. Assis, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A proteinase inhibitor from Caesalpinia echinata (pau-brasil) seeds for plasma kallikrein, plasmin and factor XIIa

C. Sampaio, A. K. Carmona, A. Faljoni-Alário, 2004, Biological chemistry.

Plasmodium falciparum histidine triad protein and calmodulin modulates calcium homeostasis and intracellular proteolysis.

A. K. Carmona, G. Montagna, A. Budu, 2018, Biochemical and biophysical research communications.

Characterization of angiotensin I-converting enzyme from anterior gills of the mangrove crab Ucides cordatus.

L. Juliano, M. Juliano, A. K. Carmona, 2015, International journal of biological macromolecules.

Characterization of two cysteine proteinases secreted by Fasciola hepatica and demonstration of their kininogenase activity.

L. Juliano, M. Juliano, E. Del Nery, 2001, Molecular and biochemical parasitology.

Specific calpain activity evaluation in Plasmodium parasites.

L. Juliano, R. Cunha, A. K. Carmona, 2015, Analytical biochemistry.

Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors.

H. Nader, C. Sampaio, A. K. Carmona, 2003, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Plasmodium falciparum proteases hydrolyze plasminogen, generating angiostatin-like fragments.

T. Paschoalin, A. K. Carmona, I. Hirata, 2014, Molecular and biochemical parasitology.

Calcium channel blockers as inhibitors of angiotensin I-converting enzyme.

L. Juliano, D. Casarini, A. K. Carmona, 1995, Hypertension.

KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.

A. K. Carmona, I. Florent, Daniel G. Rivera, 2017, Bioorganic & medicinal chemistry.

Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L.

L. Juliano, M. Juliano, D. Brömme, 2004, Archives of biochemistry and biophysics.

Angiotensin Converting Enzyme Regulates Cell Proliferation and Migration

V. Freire, M. Leite, A. M. de Paula, 2016, PloS one.

Thimet oligopeptidase EC 3.4.24.15 is a major liver kininase.

A. K. Carmona, H. M. Molina, D. Borges, 2000, Life sciences.

A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay

L. Juliano, M. Juliano, E. Sturrock, 2006, Nature Protocols.

Characterization of a prolyl endopeptidase (kininase) from human urine using fluorogenic quenched substrates.

L. Juliano, M. Juliano, D. Casarini, 2000, The international journal of biochemistry & cell biology.

Recombinant expression and characterization of a cysteine peptidase from Xanthomonas citri subsp citri.

A. Soares-Costa, F. Henrique-Silva, M. T. Novo, 2012, Genetics and molecular research : GMR.

Characterization of a kinin inactivating serine endopeptidase H2 (kininase) from human urine using fluorogenic substrates.

L. Juliano, M. Juliano, D. Casarini, 1999, Immunopharmacology.

Liver bradykinin-inactivating-endopeptidase is similar to the metalloendopeptidase (EC 3.4.24.15).

L. Juliano, A. K. Carmona, H. M. Molina, 1996, Immunopharmacology.

Determination of angiotensin I-converting enzyme activity in equine blood: lack of agreement between methods of analysis

H. Davies, G. Anderson, T. Ryan, 2011, Journal of veterinary science.

Inhibition of malaria parasite Plasmodium falciparum development by crotamine, a cell penetrating peptide from the snake venom

M. Hayashi, E. Oliveira, A. K. Carmona, 2016, Peptides.

Association between circulating angiotensin-converting enzyme and exercise-induced pulmonary haemorrhage in Thoroughbred racehorses.

F. A. Ronchi, A. K. Carmona, R. Slocombe, 2012, Research in veterinary science.

Involvement of sex hormones, oxidative stress, ACE and ACE2 activity in the impairment of renal function and remodelling in SHR.

A. K. Carmona, Á. Gava, R. Aires, 2020, Life sciences.

Phenolic compounds in raw and cooked rice (Oryza sativa L.) and their inhibitory effect on the activity of angiotensin I-converting enzyme

A. K. Carmona, U. M. Marquez, N. V. Mira, 2011 .

Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates.

L. Juliano, M. Juliano, W. Simmons, 2005, The Biochemical journal.

Biochemical characterization of human cathepsin X revealed that the enzyme is an exopeptidase, acting as carboxymonopeptidase or carboxydipeptidase.

D. Turk, L. Juliano, M. Juliano, 2000, European journal of biochemistry.

Improvement of cathepsin S detection using a designed FRET peptide based on putative natural substrates

M. Juliano, D. Brömme, A. K. Carmona, 2010, Peptides.

Correction: Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats

E. L. Dalpiaz, A. K. Carmona, S. Gouvea, 2015, PloS one.

South American rattlesnake cationic polypeptide crotamine trafficking dynamic in Plasmodium falciparum-infected erythrocytes: Pharmacological inhibitors, parasite cycle and incubation time influences in uptake.

M. Hayashi, A. K. Carmona, J. D. Campeiro, 2022, Toxicon : official journal of the International Society on Toxinology.

Overexpression of Plasmodium falciparum M1 Aminopeptidase Promotes an Increase in Intracellular Proteolysis and Modifies the Asexual Erythrocytic Cycle Development

A. K. Carmona, Jorge González-Bacerio, A. Budu, 2021, Pathogens.

Kinetic characterization of recombinant PfAM 1 , a M 1-aminopeptidase from Plasmodium falciparum ( Aconoidasida : Plasmodiidae ) , using fluorogenic peptide substrates

A. K. Carmona, María, M. Gazarini, 2015 .

Improvement of antimalarial activity of a 3-alkylpiridine alkaloid analog by replacing the pyridine ring to a thiazole-containing heterocycle: Mode of action, mutagenicity profile, and Caco-2 cell-based permeability.

G. R. da Silva, A. K. Carmona, R. Ribeiro-Viana, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity.

E. Sturrock, A. K. Carmona, S. Schwager, 2005, The Biochemical journal.

Inhibition of angiotensin converting enzyme and potentiation of bradykinin by retro-inverso analogues of short peptides and sequences related to angiotensin I and bradykinin.

L. Juliano, A. K. Carmona, 1996, Biochemical pharmacology.

Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins

P. Rosenthal, L. Juliano, M. Juliano, 2012, Malaria Journal.

Malaria infection promotes a selective expression of kinin receptors in murine liver

J. Pesquero, A. K. Carmona, N. Barros, 2019, Malaria Journal.

Kinetic characterization of the Escherichia coli oligopeptidase A (OpdA) and the role of the Tyr(607) residue.

M. Juliano, T. Paschoalin, L. Travassos, 2010, Archives of biochemistry and biophysics.

Paramagnetic bradykinin analogues as substrates for angiotensin I-converting enzyme: Pharmacological and conformation studies.

C. Nakaie, S. Schreier, L. Malavolta, 2016, Bioorganic chemistry.

Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells

C. Nakaie, J. Pesquero, J. Chagas, 2019, Inflammation Research.

Angiotensin I-converting enzyme (ACE) activity and expression in rat central nervous system after sleep deprivation

S. Tufik, J. Chagas, V. D’Almeida, 2011, Biological chemistry.

Human plasma plasminogen internalization route in Plasmodium falciparum-infected erythrocytes

A. K. Carmona, Rita Coimbra, A. Budu, 2020, Malaria Journal.

Proteolysis assessment in isolated Plasmodium falciparum living cells at the asexual blood stages

A. K. Carmona, Laritza Rojas, A. Budu, 2018 .

Hypervalent organotellurium compounds as inhibitors of P. falciparum calcium-dependent cysteine proteases.

F. Varotti, R. Cunha, A. K. Carmona, 2016, Parasitology international.

Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L

D. Turk, L. Juliano, M. Juliano, 2005, Biological chemistry.

D. Casarini, T. Fernandes, N. Y. Hashimoto, 2011, Hypertension.

Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X‐linked hypophosphatemia

M. McKee, A. K. Carmona, D. Assis, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

PnPP‐19, a spider toxin peptide, induces peripheral antinociception through opioid and cannabinoid receptors and inhibition of neutral endopeptidase

A. K. Carmona, M. E. Lima, I. Duarte, 2016, British journal of pharmacology.

Defining the substrate specificity of mouse cathepsin P.

L. Juliano, M. Juliano, A. K. Carmona, 2005, Archives of biochemistry and biophysics.

Specificity comparison of a serine endopeptidase (SH1) and a serine thiol endopeptidase (STH2) purified from human urine.

L. Juliano, M. Juliano, D. Casarini, 2004, The international journal of biochemistry & cell biology.

Hypervalent organotellurium compounds as inhibitors of P. falciparum calcium-dependent cysteine proteases.

F. Varotti, R. Cunha, A. K. Carmona, 2016, Parasitology international.

KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.

A. K. Carmona, I. Florent, Daniel G. Rivera, 2017, Bioorganic & medicinal chemistry.