G. Gibbons

S. Coppack, K. Frayn, R. Fisher, 1993, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

The formation of cholest-5-ene-3 ,26-diol as an intermediate in the conversion of cholesterol into bile acids by liver mitochondria.

G. Gibbons, K. Mitropoulos, N. Myant, 1972, The Biochemical journal.

Effect of trans-1,4-bis(2-chlorobenzylaminomethyl) cyclohexane dihydrochloride and carbon monoxide on hepatic cholesterol biosynthesis from 4,4,-dimethyl sterols in vitro.

G. Gibbons, K. Mitropoulos, 1975, Biochimica et biophysica acta.

Metabolism of hydroxy sterols by rat liver.

T. Baillie, C. Pullinger, G. Gibbons, 1980, Biochimica et biophysica acta.

Effect of nutritional state on the utilization of fatty acids for hepatitic triacylglycerol synthesis and secretion as very-low-density lipoprotein.

G. Gibbons, F. J. Burnham, 1991, The Biochemical journal.

Biochemistry of Cholesterol

G. Gibbons, N. Myant, K. Mitropoulos, 1982 .

Microsomal triglyceride transfer protein activity remains unchanged in rat livers under conditions of altered very-low-density lipoprotein secretion.

J. Scott, R. Pease, G. Gibbons, 1995, The Biochemical journal.

Separation of lipoprotein fractions by ultracentrifugation: investigation of analytical recovery with sequential flotation and density gradient procedures.

K. Frayn, R. Fisher, G. Gibbons, 1994, Clinica chimica acta; international journal of clinical chemistry.

The role of pancreatic hormones in the regulation of lipid storage, oxidation and secretion in primary cultures of rat hepatocytes. Short- and long-term effects.

J. Sparks, C. Sparks, G. Gibbons, 1992, The Biochemical journal.

Cholesterol precursor pools for the synthesis of cholic and chemodeoxycholic acids in rats.

G. Gibbons, S. Balasubramaniam, N. Myant, 1974, The Journal of biological chemistry.

Insulin Inhibits the Maturation Phase of VLDL Assembly via a Phosphoinositide 3-Kinase—Mediated Event

G. Gibbons, A. Brown, 2001, Arteriosclerosis, thrombosis, and vascular biology.

Effect of dietary fish oil on the sensitivity of hepatic lipid metabolism to regulation by insulin.

G. Gibbons, P. Baker, Paul Wayne Baker, 2000, Journal of lipid research.

Long-term maintenance of high rates of very-low-density-lipoprotein secretion in hepatocyte cultures. A model for studying the direct effects of insulin and insulin deficiency in vitro.

G. Gibbons, S. Bartlett, J. Duerden, 1989, The Biochemical journal.

Storage, mobilization and secretion of cytosolic triacylglycerol in hepatocyte cultures. The role of insulin.

G. Gibbons, J. Duerden, 1990, The Biochemical journal.

Insulin, diabetes and hepatic very-low-density lipoprotein metabolism.

G. Gibbons, 1989, Biochemical Society transactions.

Microsomal membrane-associated apoB is the direct precursor of secreted VLDL in primary cultures of rat hepatocytes.

G. Gibbons, A. Hebbachi, Geoffrey F. Gibbons, 2001, Journal of lipid research.

Increased rates of hepatic cholesterogenesis and fatty acid synthesis in septic rats in vivo: evidence for the possible involvement of insulin.

D. Williamson, G. Gibbons, P. R. D. de Vasconcelos, 1989, Clinical science.

Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin.

K. Bulmer, M. Holness, M. Sugden, 2002, The Biochemical journal.

Regulation of VLDL secretion in primary culture of rat hepatocytes: involvement of cAMP and cAMP‐dependent protein kinases

J. Sparks, C. Sparks, G. Gibbons, 1994, European journal of clinical investigation.

The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.

A. Soutar, G. Gibbons, D. Wade, 2000, The Biochemical journal.

The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.

A. Soutar, G. Gibbons, D. Wade, 2000, The Biochemical journal.

Diurnal variation in the activity of cholesterol 7α‐hydroxylase in the livers of fed and fasted rats

G. Gibbons, K. Mitropoulos, S. Balasubramaniam, 1972, FEBS letters.

Changes in the sensitivity of lipogenesis in rat hepatocytes to hormones and precursors over the diurnal cycle and during longer-term starvation of donor animals.

C. Pullinger, G. Gibbons, Ó. Björnsson, 1984, Journal of lipid research.

Secretion and storage of newly synthesized hepatic triacylglycerol fatty acids in vivo in different nutritional states and in diabetes.

G. Gibbons, J. Duerden, 1988, The Biochemical journal.

Metabolic characteristics of a human hepatoma cell line stably transfected with hormone-sensitive lipase.

R. Pease, J. Tree, G. Gibbons, 1999, The Biochemical journal.

Results in Different Effects on Hepatocellular ApoB Metabolism and Secretion Administration of n-3 Fatty Acids in the Diets of Rats or Directly to Hepatocyte Cultures

G. Gibbons, A. Hebbachi, A. Brown, 1998 .

The sterols of some marine red algae

G. Gibbons, 1967 .

A method for the rapid qualitative and quantitative analysis of 4,4-dimethyl sterols.

G. Gibbons, K. Mitropoulos, K. Ramananda, 1973, Journal of lipid research.

Lanosterol 14α-demethylase. Similarity of the enzyme system from yeast and rat liver

G. Gibbons, K. Mitropoulos, B. Reeves, 1976, Steroids.

Effect of triarimol on cholesterol biosynthesis in rat-liver subcellular.

G. Gibbons, K. Mitropoulos, 1976, Biochemical and biophysical research communications.

A possible role for cytochrome P-450 during the biosynthesis of zymosterol from lanosterol by Saccharomyces cerevisiae.

G. Gibbons, K. Mitropoulos, K. Alexander, 1974, Biochemical and biophysical research communications.

A relationship between the activities of hepatic lanosterol 14 alpha-demethylase and 3-hydroxy-3-methylglutaryl-CoA reductase.

C. Pullinger, G. Gibbons, C. Marco de la Calle, 1988, The Biochemical journal.

The rôle of cytochrome P-450 in cholesterol biosynthesis.

G. Gibbons, K. Mitropoulos, 1973, European journal of biochemistry.

The metabolic sequence by which some 4,4-dimethyl sterols are converted into cholesterol.

G. Gibbons, 1974, The Biochemical journal.

The effect of carbon monoxide on the nature of the accumulated 4,4-dimethyl sterol precursors of cholesterol during its biosynthesis from (2-14C)mevalonic acid in vitro.

G. Gibbons, K. Mitropoulos, 1973, The Biochemical journal.

Inhibition of cholesterol biosynthesis by carbon monoxide: accumulation of lanosterol and 24,25-dihydrolanosterol.

G. Gibbons, K. Mitropoulos, 1972, The Biochemical journal.

Lanosterol 14alpha-demethylase. The metabolism of some potential intermediates by cell-free systems from rat liver.

C. Pullinger, G. Gibbons, K. Mitropoulos, 1976, Biochemical and biophysical research communications.

Effects of various oxygenated sterols on cellular sterol biosynthesis in Chinese hamster lung cells resistant to 25-hydroxycholesterol.

W. Cavenee, G. Gibbons, A. Kandutsch, 1979, Biochimica et biophysica acta.

Existence of metabolic reservoirs in the later stages of the cholesterol biosynthetic pathway.

G. Gibbons, 1977, Biochemical and biophysical research communications.

Oxidative metabolism of cholesterol precursors: Sensitivity to ketoconazole, an inhibitor of cytochrome P-450

J. Iglesias, G. Gibbons, 1989, Steroids.

The evolution of plasma cholesterol: direct utility or a "spandrel" of hepatic lipid metabolism?

G. Gibbons, P. J. Babin, 2009, Progress in lipid research.

Characterization of the Rodent Genes for Arylacetamide Deacetylase, a Putative Microsomal Lipase, and Evidence for Transcriptional Regulation* 210

R. Pease, G. Gibbons, E. Saggerson, 2001, The Journal of Biological Chemistry.

The phylogenetic distribution of sterols in tracheophytes

G. Patterson, G. Gibbons, W. Nes, 1977, Lipids.

Effects of oleate and compactin on the metabolism and secretion of cholesterol and cholesteryl ester by rat hepatocytes.

C. Pullinger, G. Gibbons, Geoffrey F. Gibbons, 1982, Biochimica et biophysica acta.

Evidence that changes in hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity are required partly to maintain a constant rate of sterol synthesis.

C. Pullinger, G. Gibbons, Ó. Björnsson, 1984, The Journal of biological chemistry.

Regulation of cholesterol synthesis in the liver and mammary gland of the lactating rat.

C. Pullinger, D. Williamson, M. Munday, 1983, The Biochemical journal.

The role of substrate supply in the regulation of cholesterol biosynthesis in rat hepatocytes.

C. Pullinger, G. Gibbons, 1983, The Biochemical journal.

Regulation of cholesterol biosynthesis in cultured cells by probable natural precursor sterols.

W. Cavenee, C. Pullinger, G. Gibbons, 1980, The Journal of biological chemistry.

A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms.

V K K Chatterjee, S. O’Rahilly, A. Meirhaeghe, 2005, Endocrinology.

Lipid balance in HepG2 cells: active synthesis and impaired mobilization.

G. Gibbons, M. Seelaender, R. Khurana, 1994, Journal of lipid research.

The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas.

G. Gibbons, D. Wiggins, D Wiggins, 1992, The Biochemical journal.

Mobilisation of triacylglycerol stores.

R. Pease, G. Gibbons, G F Gibbons, 2000, Biochimica et biophysica acta.

Selective recruitment of ApoB-48 for the assembly of VLDL in rat triacylglycerol-enriched hepatocytes.

G. Gibbons, D. Wiggins, P. Coussons, 1996, Arteriosclerosis, thrombosis, and vascular biology.

Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes.

J. Sparks, C. Sparks, G. Gibbons, 1992, The Biochemical journal.

A role for PPARalpha in the control of SREBP activity and lipid synthesis in the liver.

G. Gibbons, D. Hauton, B. Knight, 2005, The Biochemical journal.

Synthesis and function of hepatic very-low-density lipoprotein.

G. Gibbons, D. Wiggins, A. Brown, 2004, Biochemical Society transactions.

Regulation of hepatic cholesterol biosynthesis. Effects of a cytochrome P-450 inhibitor on the formation and metabolism of oxygenated sterol products of lanosterol.

J. Iglesias, G. Gibbons, 1989, The Biochemical journal.

Intracellular triacylglycerol lipase: its role in the assembly of hepatic very-low-density lipoprotein (VLDL).

G. Gibbons, D. Wiggins, 1995, Advances in enzyme regulation.

Concerning the role of lanosterol and cycloartenol in steroid biosynthesis.

T. Goodwin, L. Goad, G. Gibbons, 1971, The Journal of biological chemistry.

Co-ordination of hepatic and adipose tissue lipid metabolism after oral glucose.

J. Bülow, K. Frayn, L. Simonsen, 1999, Journal of lipid research.

Peripheral triacylglycerol extraction in the fasting and post-prandial states.

S. Coppack, K. Frayn, K. Frayn, 1991, Clinical science.

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver.

Jeremy K Nicholson, Julian L Griffin, J. Griffin, 2004, Physiological genomics.

Chylomicrons are the preferred substrate for lipoprotein lipase in vivo.

S. Coppack, K. Frayn, R. Fisher, 1991, Biochemical Society transactions.

Disturbances in the normal regulation of SREBP-sensitive genes in PPARα-deficient mice

G. Gibbons, S. Humphreys, B. Knight, 2001 .

From gallstones to genes: Two hundred years of sterol research. A tribute to George J. Schroepfer Jr.

G. Gibbons, 2002, Lipids.

The functional efficiency of lipogenic and cholesterogenic gene expression in normal mice and in mice lacking the peroxisomal proliferator-activated receptor-alpha (PPAR-alpha).

G. Gibbons, B. Knight, D. Wiggins, 2002, Advances in enzyme regulation.

Decreased hepatic expression of the low-density lipoprotein (LDL) receptor and LDL receptor-related protein in aging rats is associated with delayed clearance of chylomicrons from the circulation.

G. Gibbons, P. A. Field, 2000, Metabolism: clinical and experimental.

Inactivation of microsomal triglyceride transfer protein impairs the normal redistribution but not the turnover of newly synthesized glycerolipid in the cytosol, endoplasmic reticulum and Golgi of primary rat hepatocytes.

G. Gibbons, A. Hebbachi, Geoffrey F. Gibbons, 1999, Biochimica et biophysica acta.

The metabolic route by which oleate is converted into cholesterol in rat hepatocytes.

C. Pullinger, G. Gibbons, C. P. Attwell Thomas, 1986, The Biochemical journal.

The sterochemistry of hydrogen elimination at C-7 during cholesterol biosynthesis in rat liver

T. Goodwin, L. Goad, G. Gibbons, 1968 .

The stereochemistry of hydrogen elimination from C-15 during cholesterol biosynthesis

T. Goodwin, L. Goad, G. Gibbons, 1968 .

Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice.

G. Gibbons, S. Humphreys, B. Knight, 2001, Journal of lipid research.

Incorporation of (2-14C, (5r)-5-3H1) mevalonic acid into cholesterol by a rat liver homogenate and into beta-sitosterol and 28-isofucosterol by larix decidua leaves.

T. Goodwin, H. Rees, L. Goad, 1969, The Biochemical journal.

Prostaglandins suppress VLDL secretion in primary rat hepatocyte cultures: relationships to hepatic calcium metabolism.

J. Sparks, C. Sparks, G. Gibbons, 1992, Journal of lipid research.

Regulation of hepatic very-low-density lipoprotein secretion in rats fed on a diet high in unsaturated fat.

C. Pullinger, G. Gibbons, 1987, The Biochemical journal.

VLDL output by hepatocytes from obese Zucker rats is resistant to the inhibitory effect of insulin.

G. Gibbons, R. Hems, D. Wiggins, 1995, The American journal of physiology.

Decreased sensitivity to the inhibitory effect of insulin on the secretion of very-low-density lipoprotein in cultured hepatocytes from fructose-fed rats.

G. Gibbons, R. Hems, D. Wiggins, 1995, Metabolism: clinical and experimental.

Arginine auxotrophs of Candida albicans deficient in argininosuccinate lyase.

G. Gibbons, D. Howard, 1986, Journal of general microbiology.

Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis

C. Lelliott, S. O’Rahilly, M. Jimenez-Linan, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of Hepatocyte Lipogenesis by Nitric Oxide Donor: Could Nitric Oxide Regulate Lipid Synthesis?

G. Gibbons, R. Hems, W. Roediger, 2004, IUBMB life.

The intracellular triacylglycerol/fatty acid cycle: a comparison of its activity in hepatocytes which secrete exclusively apolipoprotein (apo) B100 very-low-density lipoprotein (VLDL) and in those which secrete predominantly apoB48 VLDL.

A. Salter, G. Gibbons, D. Wiggins, 1998, The Biochemical journal.

Glucose phosphorylation is essential for the turnover of neutral lipid and the second stage assembly of triacylglycerol-rich ApoB-containing lipoproteins in primary hepatocyte cultures.

G. Gibbons, D. Wiggins, A. Brown, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Hepatocyte Cultures Stage Assembly of Triacylglycerol-Rich ApoB-Containing Lipoproteins in Primary Glucose Phosphorylation Is Essential for the Turnover of Neutral Lipid and the Second Print

G. Gibbons, D. Wiggins, 1999 .

The relationship between the rate of hepatic sterol synthesis and the incorporation of [3H]water.

C. Pullinger, G. Gibbons, 1983, Journal of Lipid Research.

Deficiency of PPARα disturbs the response of lipogenic flux and of lipogenic and cholesterogenic gene expression to dietary cholesterol in mouse white adipose tissue

K. Frayn, G. Gibbons, B. Knight, 2005 .