C. Punchihewa

发表

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2013, Nature Genetics.

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.

Gary D Bader, David T. W. Jones, V. P. Collins, 2015, Cancer cell.

Identification of Small Molecule Proliferating Cell Nuclear Antigen (PCNA) Inhibitor That Disrupts Interactions with PIP-box Proteins and Inhibits DNA Replication*

R. Heath, H. Hashimoto, A. Inoue, 2012, The Journal of Biological Chemistry.

Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis.

A. Inoue, C. Punchihewa, Benny J. Evison, 2013, Bioorganic & medicinal chemistry.

Nature Genetics Advance Online Publication

Heather L. Mulder, Erin K. Hedlund, R. Wilson, 2022 .

Erratum: C11orf95-RELA fusions drive oncogenic NF-Î° B signalling in ependymoma (Nature (2014) 506 (451-455 ) DOI:10.1038/nature13109)

Erin K. Hedlund, Michael C. Rusch, R. Wilson, 2014 .

Therapeutic Targets and Drugs II: G-Quadruplex and G-Quadruplex Inhibitors

Danzhou Yang, C. Punchihewa, 2009 .

Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.

N. Mahindroo, H. Kimura, M. Connelly, 2009, Journal of medicinal chemistry.

Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents

N. Mahindroo, C. Punchihewa, N. Fujii, 2009 .

Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway.

N. Mahindroo, B. Yan, M. Connelly, 2010, Bioorganic & medicinal chemistry.

Sequence requirement and subtype specificity in the high‐affinity interaction between human frizzled and dishevelled proteins

C. Punchihewa, R. Cassell, Patrick Rodrigues, 2009, Protein science : a publication of the Protein Society.

Hedgehog-Gli signaling pathway inhibitors as anticancer agents.

N. Mahindroo, C. Punchihewa, N. Fujii, 2009, Journal of medicinal chemistry.

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation

Roger A. Jones, Danzhou Yang, C. Punchihewa, 2007, Nucleic acids research.

Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence

Roger A. Jones, Danzhou Yang, C. Punchihewa, 2007, Nucleic acids research.

C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma

Li Ding, Elaine R. Mardis, Timothy N. Phoenix, 2014, Nature.

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

Heather L. Mulder, Michael C. Rusch, R. Wilson, 2016, Acta Neuropathologica.

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas

David T. W. Jones, M. Roussel, M. Kool, 2018, Acta Neuropathologica.

DNA and DNA -interacting proteins as anticancer drug targets

C. Punchihewa, 2006 .

A structure-activity relationship study of small-molecule inhibitors of GLI1-mediated transcription.

M. Connelly, C. Punchihewa, N. Fujii, 2011, Biopolymers.

Posterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups

D. Ellison, R. Tatevossian, J. Dalton, 2014, Acta Neuropathologica Communications.

DNA sequence selectivity of human topoisomerase I‐mediated DNA cleavage induced by camptothecin

Danzhou Yang, C. Punchihewa, M. Carver, 2009, Protein science : a publication of the Protein Society.

Functional regulation of cystic fibrosis transmembrane conductance regulator-containing macromolecular complexes: a small-molecule inhibitor approach.

B. Yan, C. Punchihewa, A. Lemoff, 2011, The Biochemical journal.

Human topoisomerase I C-terminal domain fragment containing the active site tyrosine is a molten globule: implication for the formation of competent productive complex.

Danzhou Yang, C. Punchihewa, J. Dai, 2007, Journal of structural biology.

XR5944: A potent inhibitor of estrogen receptors

Danzhou Yang, C. Punchihewa, N. Sidell, 2007, Molecular Cancer Therapeutics.

Novel DNA Bis-intercalation by MLN944, a Potent Clinical Bisphenazine Anticancer Drug*

Danzhou Yang, A. Ooi, C. Punchihewa, 2004, Journal of Biological Chemistry.

Corrigendum: C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma

Heather L. Mulder, Erin K. Hedlund, R. Wilson, 2014, Nature.

Posterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups

D. Ellison, R. Tatevossian, J. Dalton, 2014, Acta neuropathologica communications.

Nature GeNetics ADVANCE ONLINE PUBLICATION

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2013 .

Indole-2-amide based biochemical antagonist of Dishevelled PDZ domain interaction down-regulates Dishevelled-driven Tcf transcriptional activity.

C. Punchihewa, N. Fujii, Neeraj Mahindroo, 2008, Bioorganic & medicinal chemistry letters.

Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor–mediated transcription

L. You, D. Jablons, C. Punchihewa, 2008, Molecular Cancer Therapeutics.

Sequence requirement and subtype specificity in the high‐affinity interaction between human frizzled and dishevelled proteins

C. Punchihewa, R. Cassell, Patrick Rodrigues, 2009, Protein science : a publication of the Protein Society.

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Erin K. Hedlund, Michael C. Rusch, L. Fulton, 2013 .

DNA sequence selectivity of human topoisomerase I‐mediated DNA cleavage induced by camptothecin

Danzhou Yang, C. Punchihewa, M. Carver, 2009, Protein science : a publication of the Protein Society.