J. Tjørnelund

发表

Toxicity of Tetracyclines and Tetracycline Degradation Products to Environmentally Relevant Bacteria, Including Selected Tetracycline-Resistant Bacteria

B. Halling‐Sørensen, G. Sengeløv, J. Tjørnelund, 2002, Archives of environmental contamination and toxicology.

Pharmacokinetic and pharmacodynamic properties of an oral formulation of the histone deacetylase inhibitor Belinostat (PXD101)

J. Plumb, J. D. de Bono, J. Tjørnelund, 2011, Cancer Chemotherapy and Pharmacology.

Synthesis, isolation and identification of glucuronides and mercapturic acids of a novel antiparasitic agent, licochalcone A.

S. Christensen, S. Hansen, U. Braumann, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

Selectivity enhancement in capillary electrophoresis using non-aqueous media

S. Hansen, I. Bjørnsdottir, J. Tjørnelund, 1996 .

Nonaqueous capillary electrophoresis — its applicability in the analysis of food, pharmaceuticals and biological fluids

S. Hansen, I. Bjørnsdottir, J. Tjørnelund, 1998, Electrophoresis.

Non-aqueous capillary electrophoresis of drugs: properties and application of selected solvents.

S. Hansen, J. Tjørnelund, 1999, Journal of biochemical and biophysical methods.

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies.

P. Greaney, C. Ireson, J. Tjørnelund, 2009, Blood.

The effect of water on separations in non-aqueous capillary electrophoresis systems

S. Hansen, J. Tjørnelund, 1997 .

Characterisation of the abiotic degradation pathways of oxytetracyclines in soil interstitial water using LC-MS-MS.

B. Halling‐Sørensen, F. Ingerslev, J. Tjørnelund, 2003, Chemosphere.

Use of metal complexation in non-aqueous capillary electrophoresis systems for the separation and improved detection of tetracyclines.

S. Hansen, J. Tjørnelund, 1997, Journal of chromatography. A.

Purification and 1H NMR spectroscopic characterization of phase II metabolites of tolfenamic acid.

S. Hansen, C. Cornett, J. Tjørnelund, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Pharmacokinetics, metabolism, and excretion of 14C-labeled belinostat in patients with recurrent or progressive malignancies

L. F. Allen, V. Boni, E. Calvo, 2016, Investigational New Drugs.

Separation of the enantiomers of ibuprofen and its major phase I metabolites in urine using capillary electrophoresis

S. Hansen, I. Bjørnsdottir, J. Tjørnelund, 1998, Electrophoresis.

Simultaneous quantitative determination of the major phase I and II metabolites of ibuprofen in biological fluids by high-performance liquid chromatography on dynamically modified silica.

S. Hansen, J. Tjørnelund, U. Sidelmann, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Stereospecific pH-dependent degradation kinetics of R- and S-naproxen-beta-l-O-acyl-glucuronide.

S. Hansen, J. Tjørnelund, U. Sidelmann, 2002, Chirality.

New metabolites of the drug 5-aminosalicylic acid. II. N-formyl-5-aminosalicylic acid.

S. Hansen, C. Cornett, J. Tjørnelund, 1991, Xenobiotica; the fate of foreign compounds in biological systems.

New metabolites of the drug 5-aminosalicylic acid. I: N-beta-D-glucopyranosyl-5-aminosalicylic acid.

S. Hansen, C. Cornett, J. Tjørnelund, 1989, Xenobiotica; the fate of foreign compounds in biological systems.

Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.

M. Sehested, S. Nielsen, W. Kiess, 2013, Journal of medicinal chemistry.

Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure.

B. Halling‐Sørensen, J. Tjørnelund, M. Loke, 2002, Chemosphere.

Determination of impurities in tetracycline hydrochloride by non-aqueous capillary electrophoresis

S. Hansen, J. Tjørnelund, 1996 .

Determination of oxytetracycline and its degradation products by high-performance liquid chromatography-tandem mass spectrometry in manure-containing anaerobic test systems.

R. Vreeken, B. Halling‐Sørensen, J. Tjørnelund, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Validation of a simple method for the determination of oxytetracycline in ointment by non-aqueous capillary electrophoresis.

S. Hansen, J. Tjørnelund, 1997, Journal of pharmaceutical and biomedical analysis.

Quantitative analysis of oxytetracycline and its impurities by LC-MS-MS.

B. Halling‐Sørensen, C. Cornett, J. Tjørnelund, 2004, Journal of pharmaceutical and biomedical analysis.

Separation of metronidazole, its major metabolites and their conjugates using dynamically modified silica

S. Hansen, C. Cornett, J. Tjørnelund, 1995 .

Separation of neutral substances by non-aqueous capillary electrophoresis through interactions with cationic additives

S. Hansen, J. Tjørnelund, 1997 .

Identification of major degradation products of 5-aminosalicylic acid formed in aqueous solutions and in pharmaceuticals

S. Hansen, C. Olsen, C. Cornett, 1992 .

Characterization of mixtures of recombinant human cytochrome P450s as a screening model for metabolic stability in drug discovery

S. Hansen, J. Tjørnelund, J. V. Andersen, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Gas chromatographic assay for N,N-dimethylglycine in urine.

S. Hansen, J. Tjørnelund, 1990, Journal of chromatography.

Identification of the amino acids of human serum albumin involved in the reaction with the naproxen acyl coenzyme A thioester using liquid chromatography combined with fluorescence and mass spectrometric detection.

I. Bjørnsdottir, J. Tjørnelund, S. Honoré Hansen, 2003, Analytical biochemistry.

A Phase 1 Pharmacokinetic and Pharmacodynamic Study of the Histone Deacetylase Inhibitor Belinostat in Patients with Advanced Solid Tumors

Robert Brown, J. Plumb, T. Evans, 2008, Clinical Cancer Research.

A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours

J. Bono, J. D. de Bono, S. Engelholm, 2010, British Journal of Cancer.

Final results of a phase I study of oral belinostat (PXD101) in patients with solid tumors.

J. Fagerberg, D. Petrylak, O. O’Connor, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Separation of cationic cis-trans (Z-E) isomers and diastereoisomers using non-aqueous capillary electrophoresis

S. Hansen, I. Bjørnsdottir, J. Tjørnelund, 1997 .

Synthesis and structural elucidation of glutathione and N-aceyl-cysteine conjugates of 5-aminosalicylic acid

S. Hansen, C. Olsen, C. Cornett, 1993 .

Identification of oxidation products of 5-aminosalicylic acid in faeces and the study of their formation in vitro.

S. Hansen, L. A. Christensen, C. Olsen, 1993, Biochemical pharmacology.

Stability of Tylosin A in manure containing test systems determined by high performance liquid chromatography.

B. Halling‐Sørensen, F. Ingerslev, J. Tjørnelund, 2000, Chemosphere.

High-performance liquid chromatographic assay of 5-aminosalicylic acid (5-ASA) and its metabolites N-beta-D-glucopyranosyl-5-ASA, N-acetyl-5-ASA, N-formyl-5-ASA and N-butyryl-5-ASA in biological fluids.

S. Hansen, J. Tjørnelund, 1991, Journal of chromatography.

Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy.

M. Sehested, L. Jensen, F. Bjorkling, 2009, Toxicology.

Worst-Case Estimations of Predicted Environmental Soil Concentrations (PEC) of Selected Veterinary Antibiotics and Residues Used in Danish Agriculture

B. Halling‐Sørensen, J. Jensen, J. Tjørnelund, 2001 .

Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines.

I. Christensen, M. Sehested, J. Tjørnelund, 2008, Cancer biomarkers : section A of Disease markers.

Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.

M. Sehested, S. Nielsen, P. B. Jensen, 2010, Journal of medicinal chemistry.

Chemical reactivity of the naproxen acyl glucuronide and the naproxen coenzyme A thioester towards bionucleophiles.

I. Bjørnsdottir, J. Tjørnelund, S. Honoré Hansen, 2002, Journal of pharmaceutical and biomedical analysis.

LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma.

H. Tawbi, E. Chu, S. Kummar, 2013, Journal of pharmaceutical and biomedical analysis.

Isolation, structural elucidation and in vitro activity of 2-acetyl-2-decarboxamido-oxytetracycline against environmental relevant bacteria, including tetracycline-resistant bacteria.

S. Hansen, B. Halling‐Sørensen, C. Cornett, 2004, Journal of pharmaceutical and biomedical analysis.

Separation of basic drug substances of very similar structure using micellar electrokinetic chromatography.

S. Hansen, I. Bjørnsdottir, J. Tjørnelund, 1995, Journal of pharmaceutical and biomedical analysis.

A comparative study of precision cut liver slices, hepatocytes, and liver microsomes from the Wistar rat using metronidazole as a model substance.

S. Hansen, C. Cornett, J. Tjørnelund, 1996, Xenobiotica; the fate of foreign compounds in biological systems.

High-performance liquid chromatographic determination of licochalcone A and its metabolites in biological fluids.

S. Hansen, J. Tjørnelund, L. Nadelmann, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Identification of major degradation products of 5-aminosalicylic acid formed in aqueous solutions and in pharmaceuticals

S. Hansen, C. Olsen, C. Cornett, 1992 .

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies.

P. Greaney, C. Ireson, J. Tjørnelund, 2009, Blood.

420 POSTER A phase I clinical trial of belinostat (PXD101) in combination with doxorubicin (BelDox) in advanced solid tumours, including soft tissue sarcomas (STS)

O. S. Nielsen, A. Norman, I. Judson, 2008 .

419 POSTER A phase I safety and pharmacokinetic (PK) study of 3 and 6 hours (h) intravenously administered belinostat (PXD101) plus carboplatin (C) and paclitaxel (P) in patients (pts) with advanced solid tumours

P. B. Jensen, J. Tjørnelund, M. Sorensen, 2008 .

A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours

J. Bono, S. Engelholm, R. Penson, 2010, British Journal of Cancer.

Toxicity of Tetracyclines and Tetracycline Degradation Products to Environmentally Relevant Bacteria, Including Selected Tetracycline-Resistant Bacteria

G. Sengeløv, J. Tjørnelund, Bent Halling-Sørensen, 2002, Archives of Environmental Contamination and Toxicology.

Coelectroosmotic separations of anions in non-aqueous capillary electrophoresis

K. Bächmann, J. Tjørnelund, A. Bazzanella, 1998 .