Ting-jian Zhang

发表

A Metabonomic Analysis of Serum from Rats Treated with Ricinine Using Ultra Performance Liquid Chromatography Coupled with Mass Spectrometry

Fan-hao Meng, Jing Peng, Shuang Cai, 2014, PloS one.

Design, synthesis and biological evaluation of erythrina derivatives bearing a 1,2,3-triazole moiety as PARP-1 inhibitors.

X. Qian, Xin-yang Li, Fan-hao Meng, 2020, Bioorganic chemistry.

Identification of Novel Src Inhibitors: Pharmacophore-Based Virtual Screening, Molecular Docking and Molecular Dynamics Simulations

Fan-hao Meng, Ting-jian Zhang, Yi Zhang, 2020, Molecules.

Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity

Xin-yang Li, Fan-hao Meng, Ting-jian Zhang, 2019, Cell Death & Disease.

Bivalent Organophosphorus Compounds—Synthesis and Acetylcholinesterase Inhibitory Activity

Ting-jian Zhang, X. Mei, J. Ning, 2013 .

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5-ASA-PABA-MAC and 5-ASA-PABA-Diamine for the Treatment of Ulcerative Colitis.

Qiushi Li, Yan-hua Mou, Ting-jian Zhang, 2022, Journal of medicinal chemistry.

Design, synthesis, and molecular docking studies of N‐(9,10‐anthraquinone‐2‐carbonyl)amino acid derivatives as xanthine oxidase inhibitors

Fan-hao Meng, Wei Yuan, Ting-jian Zhang, 2018, Chemical biology & drug design.

Design, synthesis and biological evaluation of 1-hydroxy-2-phenyl-4-pyridyl-1H-imidazole derivatives as xanthine oxidase inhibitors.

Fan-hao Meng, Ting-jian Zhang, Shaojie Wang, 2018, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of N-(4-alkoxy-3-cyanophenyl)isonicotinamide/nicotinamide derivatives as novel xanthine oxidase inhibitors.

Lin Wang, Fan-hao Meng, Ting-jian Zhang, 2017, European journal of medicinal chemistry.

Synthesis and evaluation of 1-phenyl-1H-1,2,3-triazole-4-carboxylic acid derivatives as xanthine oxidase inhibitors.

Lin Wang, Fan-hao Meng, Ting-jian Zhang, 2017, Bioorganic & medicinal chemistry letters.

Discovery and biological evaluation of some (1H-1,2,3-triazol-4-yl)methoxybenzaldehyde derivatives containing an anthraquinone moiety as potent xanthine oxidase inhibitors.

Lin Wang, Fan-hao Meng, Wei Yuan, 2017, Bioorganic & medicinal chemistry letters.

(E)-2-styrylanthracene-9,10-dione derivatives as novel fluorescent probes: synthesis, photophysical properties and application in mitochondria imaging.

Lin Wang, Fan-hao Meng, Ting-jian Zhang, 2022, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Design, synthesis and biological evaluation of N-(4-alkoxy-3-(1H-tetrazol-1-yl)phenyl) heterocyclic aromatic amide derivatives as xanthine oxidase inhibitors.

Fan-hao Meng, Ting-jian Zhang, Xu Zhang, 2022, Bioorganic chemistry.

Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.

Jing-wei Liang, Xin-yang Li, Fan-hao Meng, 2019, Bioorganic chemistry.

2-((1-Phenyl-1H-1,2,3-triazol-4-yl)methyl)-2-azabicyclo[3.2.1]octan-3-one derivatives: Simplification and modification of aconitine scaffold for the discovery of novel anticancer agents.

X. Qian, Jing-wei Liang, Xin-yang Li, 2020, European journal of medicinal chemistry.

Metabolic Epoxidation Is a Critical Step for the Development of Benzbromarone-Induced Hepatotoxicity

Ting-jian Zhang, Jiang Zheng, Ying Peng, 2017, Drug Metabolism and Disposition.

Predicting potential antitumor targets of Aconitum alkaloids by molecular docking and protein–ligand interaction fingerprint

Jing-wei Liang, Fan-hao Meng, Ting-jian Zhang, 2016, Medicinal Chemistry Research.

Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.

Jing-wei Liang, Xin-yang Li, Fan-hao Meng, 2018, European journal of medicinal chemistry.

Novel 4,5-dihydrospiro[benzo[c]azepine-1,1'-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation.

Xin-yang Li, Fan-hao Meng, Ting-jian Zhang, 2021, Bioorganic chemistry.

Design, synthesis and anticancer activities evaluation of novel 5H-dibenzo[b,e]azepine-6,11-dione derivatives containing 1,3,4-oxadiazole units.

Jing-wei Liang, Xin-yang Li, Fan-hao Meng, 2018, Bioorganic & medicinal chemistry letters.

Intramolecular hydrogen bond interruption and scaffold hopping of TMC-5 led to 2-(4-alkoxy-3-cyanophenyl)pyrimidine-4/5-carboxylic acids and 6-(4-alkoxy-3-cyanophenyl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-ones as potent pyrimidine-based xanthine oxidase inhibitors.

Ting-jian Zhang, M. Sun, Bing Zhang, 2021, European journal of medicinal chemistry.

Synthesis and evaluation of 1-hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid derivatives as non-purine xanthine oxidase inhibitors.

Chunfu Wu, Jian Wang, Ting-jian Zhang, 2015, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of N-(3-(1H-tetrazol-1-yl)phenyl)isonicotinamide derivatives as novel xanthine oxidase inhibitors.

Fan-hao Meng, Ting-jian Zhang, Yi Zhang, 2019, European journal of medicinal chemistry.

Synthesis and evaluation of the alpha-glucosidase inhibitory activity of 3-[4-(phenylsulfonamido)benzoyl]-2H-1-benzopyran-2-one derivatives.

Ting-jian Zhang, Shaojie Wang, Ju-fang Yan, 2010, European journal of medicinal chemistry.

Synthesis of some 5-phenylisoxazole-3-carboxylic acid derivatives as potent xanthine oxidase inhibitors.

Ting-jian Zhang, Jian Wang, Mingxing Xue, 2010, European journal of medicinal chemistry.

A possible covalent xanthine oxidase inhibitor TS10: Inhibition mechanism, metabolites identification and PDPK assessment.

Lin Wang, Fan-hao Meng, Ting-jian Zhang, 2022, Bioorganic chemistry.

Design, synthesis and structure-activity relationship of N-phenyl aromatic amide derivatives as novel xanthine oxidase inhibitors.

Fan-hao Meng, Ting-jian Zhang, Xu Zhang, 2023, Bioorganic chemistry.

Design, synthesis, and biological evaluation of 5‐(4‐(pyridin‐4‐yl)‐1H‐1,2,3‐triazol‐1‐yl)benzonitrile derivatives as xanthine oxidase inhibitors

Fan-hao Meng, Ting-jian Zhang, Yi Zhang, 2018, Chemical biology & drug design.

(E)-2-Styrylanthracene-9,10-dione: A new type of fluorescent probe core and its application in specific mitochondria imaging

Fan-hao Meng, Lin Wang, Ting-jian Zhang, 2021, Dyes and Pigments.

Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity

Xin-yang Li, Fan-hao Meng, Ting-jian Zhang, 2019, Cell Death & Disease.

Predicting potential antitumor targets of Aconitum alkaloids by molecular docking and protein–ligand interaction fingerprint

Jing-wei Liang, Fan-hao Meng, Ting-jian Zhang, 2016, Medicinal Chemistry Research.

Synthesis and evaluation of the alpha-glucosidase inhibitory activity of 3-[4-(phenylsulfonamido)benzoyl]-2H-1-benzopyran-2-one derivatives.

Ting-jian Zhang, Shaojie Wang, Ju-fang Yan, 2010, European journal of medicinal chemistry.

Discovery of 4-(phenoxymethyl)-1H-1,2,3-triazole derivatives as novel xanthine oxidase inhibitors.

Fan-hao Meng, Ting-jian Zhang, P. Lu, 2022, Bioorganic & medicinal chemistry letters.

Development of a novel UHPLC-MS/MS method for the quantification of corynoxeine: Application to pharmacokinetics and tissue distribution studies in normal and chronic unpredictable mild stress-induced depression rats.

Lin Wang, Fan-hao Meng, Nan Zhao, 2023, Journal of pharmaceutical and biomedical analysis.

Small molecular CD73 inhibitors: Recent progress and future perspectives.

Ting-jian Zhang, Xu Zhang, Qiu-yin Wang, 2023, European journal of medicinal chemistry.

Comparative pharmacokinetics study of orientin in rat plasma by UHPLC-MS/MS after intravenous administration of single orientin and Trollius chinensis Bunge extract.

Lin Wang, Fan-hao Meng, Nan Zhao, 2018, Biomedical chromatography : BMC.