R. Šink

发表

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.

C. Contreras-Martel, D. Patin, D. Blanot, 2011, ACS medicinal chemistry letters.

Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F.

S. Gobec, M. Hrast, R. Šink, 2014, Bioorganic chemistry.

Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.

S. Turk, D. Patin, D. Blanot, 2010, Journal of medicinal chemistry.

Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).

C. Contreras-Martel, D. Blanot, A. Dessen, 2011, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of N‐Acylhydrazones as Inhibitors of MurC and MurD Ligases

I. Chopra, J. Bostock, D. Blanot, 2008, ChemMedChem.

Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid.

B. Joris, S. Grdadolnik, C. Contreras-Martel, 2011, European journal of medicinal chemistry.

MurD enzymes: some recent developments

D. Mengin-Lecreulx, D. Patin, D. Blanot, 2013, Biomolecular concepts.

New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold.

David Barros, L. Ballell-Pages, C. Chung, 2016, European journal of medicinal chemistry.

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

J. Kos, B. Malawska, M. Perše, 2016, Scientific Reports.

Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited

C. Contreras-Martel, D. Blanot, A. Dessen, 2016, PloS one.

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.

J. Kos, N. Coquelle, J. Colletier, 2018, Journal of medicinal chemistry.

Photosensitized transformations involving electronic energy transfer in natural waters: role of humic substances

R. Zepp, P. F. Schlotzhauer, R. Šink, 1985 .

Synthesis and characterization of a series of macrocyclic chelates containing O and N donors: Prospects for use as NMR shift agents for alkali-metal cations

A. Sherry, R. Šink, D. Buster, 1990 .

Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis.

S. Turk, David Barros, L. Ballell-Pages, 2015, Journal of medicinal chemistry.

New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation.

C. Contreras-Martel, D. Patin, D. Blanot, 2011, European journal of medicinal chemistry.

False positives in the early stages of drug discovery.

Stanislav Gobec, S. Gobec, A. Zega, 2010, Current medicinal chemistry.

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents.

N. Coquelle, J. Colletier, Janez Mravljak, 2015, Bioorganic & medicinal chemistry.

Simple and effective preparation of amino sulfonylureas from amino acids: application to the synthesis of amino sulfonylurea-containing peptidomimetics

A. Zega, R. Šink, 2008 .