P. Kristian

发表

Computational study to assign structure, tautomerism, E/Z and s-cis/s-trans isomerism, π-delocalization, partial aromaticity, and the ring size of 1,3-thiazolidin-4-ones and 1,3-thiazin-4-ones formed from thiosemicarbazides

S. Böhm, Jana Tomaščiková, J. Imrich, 2009 .

Multifunctional properties of novel tacrine congeners: cholinesterase inhibition and cytotoxic activity

P. Kristian, D. Sabolova, M. Kožurková, 2018, Journal of applied toxicology : JAT.

Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules.

K. Kuča, D. Jun, M. Valko, 2016, Journal of inorganic biochemistry.

Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers.

S. Böhm, K. Kuča, M. Pohanka, 2014, International journal of biological macromolecules.

Determination of the binding affinities of plasmid DNA using fluorescent intercalators possessing an acridine skeleton.

J. Imrich, I. Danihel, P. Kristian, 2006, International journal of biological macromolecules.

Stereochemistry, tautomerism, and reactions of acridinyl thiosemicarbazides in the synthesis of 1,3-thiazolidines †

K. Pihlaja, J. Imrich, P. Kristian, 2006 .

Studies of the vibrational frequencies ν asym.NCS of m - and p -substituted phenylisothiocyanates in various solvents

P. Kristian, K. Antos, Š. Kováč, 1965 .

Synthesis and properties of novel biologically interesting polycyclic 1,3,4-oxadiazoles containing acridine/acridone moieties

S. Böhm, Jana Tomaščiková, J. Imrich, 2009 .

Regioselectivity and Tautomerism of Novel Five-Membered Ring Nitrogen Heterocycles Formed via Cyclocondensation of Acylthiosemicarbazides

S. Böhm, Jana Tomaščiková, J. Imrich, 2008, Molecules.

Heterocyclization of (Acridin-9-yl)thiosemicarbazides with Dimethyl Acetylenedicarboxylate

S. Böhm, Jana Tomaščiková, J. Imrich, 2007 .

Novel trisubstituted acridines as human telomeric quadruplex binding ligands.

V. Brabec, J. Kašpárková, P. Fedoročko, 2014, Bioorganic chemistry.

A new look at 9‐substituted acridines with various biological activities

P. Kristian, D. Sabolova, M. Kožurková, 2020, Journal of applied toxicology : JAT.

Antifungal activity of isothiocyanates and related compounds. II. Mononuclear aromatic isothiocyanates.

P. Kristian, M. Zemanová, K. Antos, 1967, Applied microbiology.

Acridine derivatives inhibit lysozyme aggregation

M. Antalík, D. Fedunova, Jana Tomaščiková, 2008, European Biophysics Journal.

Synthesis of 2-substituted 5-arylidenethiazolin-4-ones from α,β-unsaturated acyl isothiocyanates

P. Kristian, P. Kutschy, M. Dzurilla, 1981 .

3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents.

V. Brabec, J. Kašpárková, P. Fedoročko, 2012, European journal of medicinal chemistry.

Neuroactive Multifunctional Tacrine Congeners with Cholinesterase, Anti-Amyloid Aggregation and Neuroprotective Properties

P. Kristian, Z. Gazova, M. Kožurková, 2011, Pharmaceuticals.

Synthesis and biological evaluation of novel tacrine derivatives and tacrine-coumarin hybrids as cholinesterase inhibitors.

K. Kuča, J. Imrich, P. Kristian, 2014, Journal of medicinal chemistry.

Regiospecific synthesis, structure and electron ionization mass spectra of 1,3-thiazolidin -4-ones containing the acridine skeleton

K. Pihlaja, J. Imrich, P. Kristian, 2005 .

Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease.

Martina Hrabinova, Kamil Kuca, Ladislav Janovec, 2012, European journal of medicinal chemistry.

Selective formation of 5- or 6-membered rings, 1,3-thiazolidin-4-one vs. 1,3-thiazin-4-one, from acridine thiosemicarbazides by the use of ethyne acid esters

S. Böhm, Jana Tomaščiková, J. Imrich, 2010 .

Regioselective syntheses, structural characterization, and electron ionization mass spectrometric behavior of regioisomeric 2,3-disubstituted 2-imino-1,3-thiazolidin-4-ones.

K. Pihlaja, J. Imrich, P. Kristian, 2004, Rapid communications in mass spectrometry : RCM.

Regioselective Synthesis of 2‐Imino‐1,3‐thiazolidin‐4‐ones by Treatment of N‐(Anthracen‐9‐yl)‐N′‐ethylthiourea with Bromoacetic Acid Derivatives

K. Pihlaja, J. Imrich, P. Kristian, 2002 .

A review on acridinylthioureas and its derivatives: biological and cytotoxic activity

P. Kristian, D. Sabolova, M. Kožurková, 2017, Journal of applied toxicology : JAT.

Bromine oxidation of N-(3 or 4-substituted phenyl)-N'-3-phenylpropenoylthioureas

J. Imrich, P. Kristian, M. Dzurilla, 1983 .

2-Isothiocyanatobenzylpyridinium bromide: an intermediate for the synthesis of 2-arylamino-4H-benzo[d][1,3]thiazines

P. Kristian, J. Gonda, 1986 .

Photocyclization of N-(3-chloro-2-benzo[ b ]thienocarbonyl)-N'-monosubstituted thioureas

J. Imrich, P. Kristian, P. Kutschy, 1986 .

Boron trifluoride-catalyzed cyclization of N-substituted-N-(3-substituted propenoyl)-thioureas: a new synthesis of 1,3-thiazines

P. Kristian, P. Kutschy, M. Dzurilla, 1985 .

Synthesis and investigation of enamine-imine tautomerism of 2,6-disubstituted 4 H -1,3-thiazin-4-ones

J. Imrich, P. Kristian, 1982 .

Synthesis, chemical properties and reactions of heterodienes. I. Spectral properties of phenyl isoselenocyanates and the polar character of the NCSe group

P. Kristian, G. Suchár, 1972 .

Cycloadditions of vinyl isocyanate and isothiocyanate with oxovinylidene- and phenyliminovinylidenetriphenylphosphoranes

J. Imrich, P. Kristian, G. D. Andreetti, 1988 .

Novel Carbohydrazide and Hydrazone Biomarkers Based on 9-Substituted Acridine and Anthracene Fluorogens

S. Böhm, Z. Bedlovičová, J. Imrich, 2010 .

Configuration and E/Z interconversion mechanism of O(S)‐allyl‐S(O)‐methyl‐N‐(acridin‐9‐yl) iminothiocarbonate

S. Böhm, K. Pihlaja, J. Imrich, 2005, Magnetic resonance in chemistry : MRC.

Synthesis, structure, and cholinergic effect of novel neuroprotective compounds bearing the tacrine pharmacophore

S. Böhm, K. Kuča, D. Jun, 2008 .

Antifungal activity of isothiocyanates and related compounds. I. Naturally occurring isothiocyanates and their analogues.

P. Kristian, M. Zemanová, K. Antos, 1967, Applied microbiology.

The antiworm activity of some natural and synthetic compounds. 3. The effect of aromatic isothiocyanates of the R-C6H4-X-C6H5NCS type on Tubatrix aceti.

P. Kristian, K. Antos, M. Uher, 1968, The Journal of antibiotics.

Antifungal activity of isothiocyanates and related compounds. 3. Derivatives of biphenyl, stilbene, azobenzene, and several polycondensed aromatic hydrocarbons.

P. Kristian, M. Zemanová, K. Antos, 1968, Applied microbiology.

Antifungal Activity of Isothiocyanates and Related Compounds

P. Kristian, M. Zemanová, K. Antos, 1967 .

Heterocycles with a pyrido[3,2- e ]-1,3-selenazine and pyrido[3,4- e ]-1,3-selenazine ring systems

P. Kristian, J. Gonda, D. Koščík, 1983 .

Reaction of α,β-unsaturated acyl isothiocyanates with alkali metal hydrosulphides

P. Kristian, M. Dzurilla, 1976 .

DNA binding acridine-thiazolidinone agents affecting intracellular glutathione.

J. Imrich, P. Kristian, M. Kožurková, 2012, Bioorganic & medicinal chemistry.

HETEROCYCLES WITH PYRIDO(3,2-E)-1,3-SELENAZINE AND PYRIDO(3,4-E)-1,3-SELENAZINE RING SYSTEMS

P. Kristian, J. Gonda, D. Koščík, 1984 .

Reaction of 4-substituted benzoyl isothiocyanates with N,N'-dicyclohexylcarbodiimide and N,N'-diphenylcarbodiimide

P. Kristian, O. Hritzová, 1978 .

Some nucleophilic reactions of 2-isothiocyanatobenzyl bromide: a new simple synthesis of 2-substituted 4H-benzo[d][1,3]-thiazines

P. Kristian, J. Gonda, 1986 .

Proflavine/acriflavine derivatives with versatile biological activities

P. Kristian, M. Kožurková, D. Sabolová, 2020, Journal of applied toxicology : JAT.

DNA binding properties and evaluation of cytotoxic activity of 9,10-bis-N-substituted (aminomethyl)anthracenes.

J. Imrich, P. Kristian, J. Busa, 2007, International journal of biological macromolecules.

Infrared spectroscopy, dipole moment, and structure study of benzoyl isothiocyanates

P. Kristian, O. Hritzová, P. Talán, 1977 .

Synthesis and geometric isomerism of 4-substituted 2-phenylethenyl isothiocyanates

P. Kristian, L. Kniežo, S. Velebný, 1978 .

Preparation and infrared spectra of substituted phenyl isothiocyanates

P. Kristian, K. Antos, Š. Kováč, 1964 .

Reactions of cysteine, its derivatives, glutathione, coenzyme A, and dihydrolipoic acid with isothiocyanates

P. Kristian, D. Podhradský, L. Drobnica, 1979, Experientia.

Phenylhydrazonopropanedinitrile derivatives of cellulose: New type of sorbent for thiol compounds

E. Šturdı́k, M. Antalík, P. Gemeiner, 1983 .

Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1',1''-(acridin-3,6-diyl)-3',3''-dialkyldiureas.

P. Fedoročko, J. Mikes, J. Imrich, 2008, Bioorganic & medicinal chemistry.

Cytotoxic activity of acridin-3,6-diyl dithiourea hydrochlorides in human leukemia line HL-60 and resistant subline HL-60/ADR.

J. Imrich, P. Kristian, M. Suchanová, 2009, International journal of biological macromolecules.

Synthesis, DNA interaction, and cytotoxic activity of a novel proflavine-dithiazolidinone pharmacophore.

J. Imrich, P. Kristian, E. Moravčíková, 2007, Bioconjugate chemistry.

Methylation of Acridin-9-ylthioureas. Structure, Fluorescence and Biological Properties of Products

S. Böhm, K. Pihlaja, N. Prónayová, 2004 .

Structure-activity relationship of acridine derivatives to amyloid aggregation of lysozyme.

F. Biscarini, E. Bystrenova, B. Chelli, 2011, Biochimica et biophysica acta.

Molecular and solid-state structure of methyl [2-(acridin-9-ylimino)-3-(tert-butylamino)-4-oxothiazolidin-5-ylidene]acetate

S. Böhm, Jana Tomaščiková, J. Imrich, 2008 .

A Convenient Synthesis of Polyfunctionally Substituted 2',2'-Bis(ethoxycarbonyl)methylene-5'-methoxycarbonyl(cyano)spiro[dihydroacridine-9(10H),4'-thiazolidines]

K. Pihlaja, J. Imrich, P. Kristian, 1999 .

Synthesis of Acetylcholinesterase Inhibitors on the Basis of 9-Isothiocyanato-1,2,3,4-tetrahydroacridine: 2-[(1,2,3,4-Tetrahydroacridin-9-yl)imino]-3-substituted 1,3-Thiazolidin-4-ones

J. Imrich, P. Kristian, G. Voss, 1998 .

9-Isothiocyanatoacridines: Convenient Synthons for New Functionalized 9-Acridinyl Derivatives

A. Linden, J. Imrich, I. Danihel, 1997 .

New Type of Spiro Heterocycles. A Convenient Synthesis of Spiro[dihydroacridine 9(10H), 4′-Thiazolines]

J. Imrich, P. Kristian, J. Berná, 1995 .

Spectroscopic, structural and theoretical studies of novel, potentially cytotoxic 4-acridonecarboxamide imines.

S. Böhm, J. Imrich, I. Danihel, 2009, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

New Approach to Synthesis of N-Substituted 9-Amino/Iminoacridines with Important Fluorescence Properties

E. Sedlák, J. Imrich, P. Kristian, 2001 .

Fluorescence Reagents for Labelling of Biomolecules. Part I. Synthesis and Spectral Characterization of 2- and 4-Substituted 9-Isothiocyanatoacridines

M. Antalík, J. Imrich, P. Kristian, 1994 .

A Simple Synthesis of 2′,5′-Disubstituted-Spiro [Dihydroacridine 9(10H), 4′-Thiazolines] by the Reaction of Corresponding 3-(Acridin-9-Yl)-Thioureas with Methyl Bromoacetate and Bromoacetonitrile

P. Kristian, G. Voss, J. Bernát, 1998 .

New Type of Spiro Heterocycles. A Convenient Synthesis of Spiro( dihydroacridine 9(10H),4′‐thiazolines).

J. Imrich, P. Kristian, J. Černák, 1996 .

Fluorescence Reagents for Labelling of Biomolecules. Part II. Reactions of 9-Isothiocyanatoacridine with Amino Acids

M. Antalík, P. Kristian, P. Oravec, 1994 .

9-Isothiocyanatoanthracene as a Versatile Starting Compound in the Chemistry of Anthracen-9-yl Derivatives

V. Sasinková, E. Sedlák, J. Imrich, 2002 .

Novel Synthesis of 3-(9′-Acridinyl)-5-substituted Tetrahydro-1,3,5-thiadiazine-2-thiones from Isothiocyanates and 1-Azonium-4-azabicyclo[2.2.2]-octane Hydrogen Sulfide

J. Imrich, P. Kristian, J. Bernát, 1996 .

Reaction of O-Alkyl-N-substituted Iminothiocarbonates with Bromoacetyl Bromide. A General Method for the Synthesis of 3-Substituted 1,3-Thiazolidine-2,4-diones

J. Imrich, P. Kristian, J. Bernát, 1996 .

An Analysis of Substituent Effects on the Proton and Carbon-13 Chemical Shifts of 2-Substituted 9-Isothiocyanatoacridines

T. Liptaj, J. Imrich, I. Danihel, 1994 .

Fluorescence Reagents for Labelling of Biomolecules. Part III. Study of the Reactions of 2- and 4-Substituted 9-Isothiocyanatoacridines with Glycine

M. Antalík, J. Imrich, P. Kristian, 1994 .

Kinetics of reactions of acyl isothiocyanates with amines

J. Imrich, P. Kristian, D. Podhradský, 1980 .

Dipole moments and structure of isothiocyanates

P. Kristian, K. Antos, A. Martvoň, 1966 .

Electronic nature of the isothiocyanato group and its effect on the basicity of acridines

R. Zahradník, P. Kristian, K. Antos, 1963 .

Synthesis of Acetylcholinesterase Inhibitors on the Basis of 9-Isothiocyanato-1,2,3,4-tetrahydroacridine: 2-[(1,2,3,4-Tetrahydroacridin-9-yl)imino] -3-substituted-1,3-thiazolidin-4-ones (VI).

J. Imrich, P. Kristian, G. Voss, 1999 .

A Convenient Synthesis of Polyfunctionally Substituted 2′,2′‐Bis(ethoxycarbonyl)methylene‐5′‐methoxycarbonyl(cyano)spiro [dihydroacridine‐9(10H),4′‐thiazolidines].

K. Pihlaja, J. Imrich, P. Kristian, 1999 .

The chemistry of the — NCS group

P. Kristian, L. Drobnica, J. Augustin, 2010 .

Adsorption of SH-containing amino acids, peptides and proteins on the 2-nitrophenylhydrazonopropanedinitrile derivative of spheron ara

M. Antalík, P. Kristian, D. Podhradský, 1985 .