P. Grellier

发表

Thiazolidinone-Related Heterocyclic Compounds as Potential Antitrypanosomal Agents

D. Kaminskyy, A. Kryshchyshyn, R. Lesyk, 2020, Azoles - Synthesis, Properties, Applications and Perspectives [Working Title].

Thiazolidinone/thiazole based hybrids - New class of antitrypanosomal agents.

D. Kaminskyy, A. Kryshchyshyn, R. Lesyk, 2019, European journal of medicinal chemistry.

Isothiochromenothiazoles-A Class of Fused Thiazolidinone Derivatives with Established Anticancer Activity That Inhibits Growth of Trypanosoma brucei brucei.

D. Kaminskyy, A. Kryshchyshyn, R. Lesyk, 2018, Scientia pharmaceutica.

Synthesis of pyrazoline-thiazolidinone hybrids with trypanocidal activity.

R. Lesyk, P. Grellier, B. Zimenkovsky, 2014, European journal of medicinal chemistry.

Detection, characterization, and screening of heme-binding molecules by mass spectrometry for malaria drug discovery.

A. Maciuk, P. Grellier, Katalina Muñoz-Durango, 2012, Analytical chemistry.

Exploring the environmental diversity of kinetoplastid flagellates in the high-throughput DNA sequencing era

J. Lukeš, J. Votýpka, V. Yurchenko, 2015, Memorias do Instituto Oswaldo Cruz.

Plasmepsin II, an Acidic Hemoglobinase from thePlasmodium falciparum Food Vacuole, Is Active at Neutral pH on the Host Erythrocyte Membrane Skeleton*

D. Goldberg, P. Grellier, D E Goldberg, 1999, The Journal of Biological Chemistry.

One-pot microwave-assisted synthesis and antimalarial activity of ferrocenyl benzodiazepines

Till Bousquet, P. Grellier, E. Mouray, 2011 .

The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum

A. Maciuk, N. Cech, A. Fournet, 2011 .

Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea

M. Litaudon, J. Gatto, M. Beniddir, 2013 .

Robust inactivation of Plasmodium falciparum in red blood cell concentrates using amustaline and glutathione pathogen reduction

Marion C Lanteri, P. Bringmann, P. Grellier, 2022, Transfusion.

Inactivation of Plasmodium falciparum in whole blood using the amustaline and glutathione pathogen reduction technology

Marion C Lanteri, A. Stassinopoulos, P. Grellier, 2020, Transfusion.

In vitro investigation of Brazilian Cerrado plant extract activity against Plasmodium falciparum, Trypanosoma cruzi and T. brucei gambiense

Sébastien Charneau, L. Espindola, P. Grellier, 2016, Natural product research.

Targeted Isolation of Hemitheion from Mostuea brunonis, a Proposed Biosynthetic Intermediate of Theionbrunonines.

M. Beniddir, P. Grellier, E. Mouray, 2021, Journal of natural products.

Streamlined targeting of Amaryllidaceae alkaloids from the bulbs of Crinum scillifolium using spectrometric and taxonomically-informed scoring metabolite annotations.

J. Gallard, M. Beniddir, P. Grellier, 2020, Phytochemistry.

Vital role for Plasmodium berghei Kinesin8B in axoneme assembly during male gamete formation and mosquito transmission

R. Sinden, S. Marques, S. Chaouch, 2019, bioRxiv.

Screening extracts of Madagascan plants in search of antiplasmodial compounds

P. Rasoanaivo, P. Grellier, D. Ramanitrahasimbola, 2004, Phytotherapy research : PTR.

Interactions between docetaxel (Taxotere) and Plasmodium falciparum-infected erythrocytes.

V. Sinou, P. Grellier, D. Guénard, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Specific human antibodies do not inhibit Trypanosoma cruzi oligopeptidase B and cathepsin B, and immunoglobulin G enhances the activity of trypomastigote-secreted oligopeptidase B.

A. Teixeira, P. Grellier, L. C. Fernandes, 2005, Microbes and infection.

Peptide derivatives specific for a Plasmodium falciparum proteinase inhibit the human erythrocyte invasion by merozoites.

M. Monsigny, R. Mayer, P. Grellier, 1991, Journal of medicinal chemistry.

Antiplasmodial Biodereplication Based on Highly Efficient Methods

A. Maciuk, J. Gallard, P. Grellier, 2020 .

Aminocyclopropanes as precursors of endoperoxides with antimalarial activity.

P. Retailleau, P. Grellier, I. Florent, 2010, Organic & biomolecular chemistry.

Dibenzocyclooctynes: Effect of Aryl Substitution on Their Reactivity toward Strain-Promoted Alkyne-Azide Cycloaddition.

R. Méallet-Renault, P. Grellier, J. Dubois, 2019, The Journal of organic chemistry.

Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).

C. Moretti, Soizic Prado, M. Litaudon, 2010, Phytochemistry.

Yeast-mediated xanthone synthesis through oxidative intramolecular cyclization.

J. Wansi, Marie-Christine Lallemand, P. Grellier, 2012, Organic letters.

Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity.

P. Grellier, E. Mouray, C. André-Barrès, 2020, ACS medicinal chemistry letters.

Antiplasmodial activity and cytotoxicity of bis-, tris-, and tetraquinolines with linear or cyclic amino linkers.

E. Davioud‐Charvet, C. Sergheraert, L. Maes, 2001, Journal of medicinal chemistry.

Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.

Sébastien Charneau, P. Grellier, B. Crousse, 2004, Journal of medicinal chemistry.

Photochemical inactivation with amotosalen and long‐wavelength ultraviolet light of Plasmodium and Babesia in platelet and plasma components

M. Steiert, Sébastien Charneau, H. Gil, 2008, Transfusion.

Dendropsophin 1, a novel antimicrobial peptide from the skin secretion of the endemic Colombian frog Dendropsophus columbianus

S. M. de Freitas, Sébastien Charneau, P. Grellier, 2018, Natural product research.

Characterization of PfDYN2, a dynamin-like protein of Plasmodium falciparum expressed in schizonts.

Sébastien Charneau, P. Grellier, I. Florent, 2007, Microbes and infection.

Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors.

P. Grellier, S. Cojean, P. Loiseau, 2016, European journal of medicinal chemistry.

Synthesis of polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.

P. Grellier, J. Dubois, S. Thoret, 2013, Bioorganic & medicinal chemistry.

Introduction of methionine mimics on 3-arylthiophene: influence on protein farnesyltransferase inhibition and on antiparasitic activity

P. Grellier, S. Cojean, P. Loiseau, 2013 .

Improvement of the trypanocidal activity of 3-arylthiophene farnesyltransferase inhibitors by modulation of their 3-aryl group

P. Grellier, E. Mouray, J. Dubois, 2012 .

Diversity of apostome ciliates, Chromidina spp. (Oligohymenophorea, Opalinopsidae), parasites of cephalopods of the Mediterranean Sea

J. Justine, M. Romdhane, H. Furuya, 2016, Parasite.

Involvement of calyculin A-sensitive phosphatase(s) in the differentiation of Trypanosoma cruzi trypomastigotes to amastigotes.

J. Blum, V. Sinou, A. Teixeira, 1999, Molecular and biochemical parasitology.

A Trypanosoma cruzi-secreted 80 kDa proteinase with specificity for human collagen types I and IV.

A. Teixeira, P. Grellier, J. Santana, 1997, The Biochemical journal.

Biodereplication of Antiplasmodial Extracts: Application of the Amazonian Medicinal Plant Piper coruscans Kunth

A. Maciuk, J. Gallard, M. Beniddir, 2022, Molecules.

New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis

P. Grellier, E. Mouray, J. Dubois, 2013, Journal of enzyme inhibition and medicinal chemistry.

Isolation and characterization of a soluble antigen complex of Plasmodium falciparum with pyrogenic properties

E. M. Riley, T. Theander, L. Hviid, 1991, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues

R. Müller, Soizic Prado, P. Grellier, 2013, Beilstein journal of organic chemistry.

Prolyl oligopeptidase of Trypanosoma brucei hydrolyzes native collagen, peptide hormones and is active in the plasma of infected mice.

Sébastien Charneau, L. Dubost, P. Grellier, 2010, Microbes and infection.

Structure and total synthesis of (-)-myrionidine and (-)-schoberine, antimalarial alkaloids from Myrioneuron nutans.

B. Bodo, P. Grellier, V. Pham, 2008, The Journal of organic chemistry.

Brazilian Cerrado Qualea grandiflora Mart. Leaves Exhibit Antiplasmodial and Trypanocidal Activities In vitro

Sébastien Charneau, P. Grellier, Thuany de Moura Cordeiro, 2017, Pharmacognosy magazine.

New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity--Part II.

G. Déléris, J. Leger, C. Jarry, 2011, European journal of medicinal chemistry.

Eumitrins C-E: Structurally diverse xanthone dimers from the vietnamese lichen Usnea baileyi.

G. Genta‐Jouve, J. Gallard, M. Beniddir, 2019, Fitoterapia.

New wedelolides, (9R)-eudesman-9,12-olide δ-lactones, from Wedelia trilobata

P. Grellier, G. Jaureguiberry, A. Jossang, 2016 .

Synthesis and antimalarial evaluation of new N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives.

C. Sergheraert, P. Melnyk, P. Grellier, 2005, Bioorganic & medicinal chemistry letters.

Trypanosoma cruzi Prolyl Oligopeptidase Tc80 Is Involved in Nonphagocytic Mammalian Cell Invasion by Trypomastigotes*

E. Davioud‐Charvet, C. Sergheraert, H. Drobecq, 2001, The Journal of Biological Chemistry.

Purification and characterization of a new 120 kDa alkaline proteinase of Trypanosoma cruzi.

M. Rodier, A. Teixeira, P. Grellier, 1992, Biochemical and biophysical research communications.

Synthesis and activity of pyrrolidinyl- and thiazolidinyl-dipeptide derivatives as inhibitors of the Tc80 prolyl oligopeptidase from Trypanosoma cruzi.

A. Teixeira, P. Grellier, J. Santana, 2000, European journal of medicinal chemistry.

Heme-binding activity of methoxyflavones from Pentzia monodiana Maire (Asteraceae).

A. Maciuk, S. Boutefnouchet, P. Grellier, 2017, Fitoterapia.

Antiplasmodial benzophenones from the trunk latex of Moronobea coccinea (Clusiaceae).

C. Moretti, Soizic Prado, P. Retailleau, 2009, Phytochemistry.

Role of Single-Electron Oxidation Potential and Lipophilicity in the Antiplasmodial in vitro Activity of Polyphenols: Comparison to Mammalian Cells

A. Nemeikaitė-Čėnienė, N. Čėnas, P. Grellier, 2008, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Clerodane and labdane diterpenoids from Nuxia sphaerocephala.

P. Rasoanaivo, P. Grellier, D. Ramanitrahasimbola, 2006, Phytochemistry.

Isolation, characterization and antiplasmodial activity of steroidal alkaloids from Funtumia elastica (Preuss) Stapf.

B. Bodo, P. Grellier, G. Zirihi, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro and in vivo antimalarial activity of N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives.

C. Sergheraert, L. Maes, P. Grellier, 2003, Journal of medicinal chemistry.

Evaluation of Nucleoside Hydrolase Inhibitors for Treatment of African Trypanosomiasis

H. D. de Koning, J. Steyaert, M. Degano, 2010, Antimicrobial Agents and Chemotherapy.

New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity.

V. Sinou, D. Parzy, C. Jarry, 2008, Bioorganic & medicinal chemistry.

"One-pot" synthesis and antimalarial activity of formamidine derivatives of 4-anilinoquinoline.

C. Sergheraert, L. Maes, P. Grellier, 2001, Chemical & pharmaceutical bulletin.

Isothiocoumarin-3-carboxylic acid derivatives: synthesis, anticancer and antitrypanosomal activity evaluation.

D. Kaminskyy, A. Kryshchyshyn, R. Lesyk, 2014, European journal of medicinal chemistry.

Design, synthesis and in vitro antimalarial activity of an acylhydrazone library.

C. Sergheraert, P. Melnyk, P. Grellier, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and antitrypanosomal activity of new 6,6,7-trisubstituted thiopyrano[2,3-d][1,3]thiazoles.

R. Lesyk, P. Grellier, D. Atamanyuk, 2012, Bioorganic & medicinal chemistry letters.

trans-Aconitic acid-based hetero-Diels-Alder reaction in the synthesis of thiopyrano[2,3-d][1,3]thiazole derivatives

R. Lesyk, A. Gzella, P. Grellier, 2017 .

Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker.

E. Davioud‐Charvet, C. Sergheraert, L. Maes, 2000, Journal of medicinal chemistry.

New Synthesis of Benzo-δ-carbolines, Cryptolepines, and Their Salts: In Vitro Cytotoxic, Antiplasmodial, and Antitrypanosomal Activities of δ-Carbolines, Benzo-δ-carbolines, and Cryptolepines

P. Grellier, F. Marsais, E. Arzel, 2001 .

Synthesis, antimalarial activity, and molecular modeling of new pyrrolo[1,2-a]quinoxalines, bispyrrolo[1,2-a]quinoxalines, bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and bispyrrolo[1,2-a]thieno[3,2-e]pyrazines.

C. Sergheraert, J. Leger, C. Jarry, 2004, Journal of medicinal chemistry.

Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii.

Olivier Duval, Pascal Richomme, Philippe Grellier, 2004, Life sciences.

Design, synthesis and antimalarial activity of novel, quinoline-based, zinc metallo-aminopeptidase inhibitors.

C. Sergheraert, P. Grellier, R. Deprez-Poulain, 2003, Bioorganic & medicinal chemistry letters.

Synthesis and antimalarial activity of new analogues of amodiaquine.

Philippe Grellier, C. Sergheraert, L. Maes, 2008, European journal of medicinal chemistry.

Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents.

G. Gosmann, S. Gnoatto, P. Grellier, 2008, Bioorganic & medicinal chemistry.

Design, synthesis and antimalarial activity of a glyoxylylhydrazone library.

C. Sergheraert, O. Melnyk, P. Melnyk, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and antimalarial evaluation of new 1,4-bis(3-aminopropyl)piperazine derivatives.

C. Sergheraert, P. Grellier, R. Deprez-Poulain, 2003, Bioorganic & medicinal chemistry letters.

Antimalarial and cytotoxic activities of ethnopharmacologically selected medicinal plants from South Vietnam.

J. Farrar, C. Dolecek, P. Caron, 2007, Journal of ethnopharmacology.

Synthesis and in vitro and in vivo antimalarial activity of new 4-anilinoquinolines.

C. Sergheraert, L. Maes, P. Grellier, 2001, Journal of medicinal chemistry.

Goniomedines A and B: unprecedented bisindole alkaloids formed through fusion of two indole moieties via a dihydropyran unit.

M. Litaudon, P. Rasoanaivo, M. Beniddir, 2012, Organic letters.

Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation, and Preliminary SAR Studies.

P. Grellier, E. Mouray, J. Dubois, 2016, Organic letters.

Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase

E. Davioud‐Charvet, N. Čėnas, P. Grellier, 2019, Molecules.

The ferroquine antimalarial conundrum: redox activation and reinvasion inhibition.

C. Biot, D. Dive, C. Slomianny, 2013, Angewandte Chemie.

In vitro antiplasmodial activity and cytotoxicity of 33 West African plants used for treatment of malaria.

B. Bodo, P. Grellier, G. Zirihi, 2005, Journal of ethnopharmacology.

Antiparasitic Ovalicin Derivatives from Pseudallescheria boydii, a Mutualistic Fungus of French Guiana Termites

D. Touboul, D. Stien, P. Grellier, 2022, Molecules.

In vitro antiparasitic activity of microbial pigments and their combination with phytosynthesized metal nanoparticles.

P. Grellier, E. Mouray, P. Satish, 2015, Parasitology international.

Pleiokomenines A and B: Dimeric Aspidofractinine Alkaloids Tethered with a Methylene Group.

G. Genta‐Jouve, J. Gallard, M. Beniddir, 2017, Organic letters.

Trends in research of antitrypanosomal agents among synthetic heterocycles.

D. Kaminskyy, A. Kryshchyshyn, R. Lesyk, 2014, European journal of medicinal chemistry.

Bioactive properties of plant species ingested by chimpanzees (Pan troglodytes schweinfurthii) in the Kibale National Park, Uganda

R. Wrangham, M. Huffman, P. Grellier, 2006, American journal of primatology.

Antiplasmodial, antitrypanosomal, and cytotoxic activities of prenylated flavonoids isolated from the stem bark of Artocarpus styracifolius.

M. Litaudon, C. Apel, P. Grellier, 2010, Planta medica.

Antiparasitic activities of medicinal plants used in Ivory Coast.

A. Laurens, R. Hocquemiller, P. Grellier, 2004, Journal of ethnopharmacology.

Synthesis of novel guttiferone A derivatives: in-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani.

J. Wansi, Marie-Christine Lallemand, N. Gaboriaud-Kolar, 2013, European journal of medicinal chemistry.

Novel Antimalarial Compounds Isolated in a Survey of Self-Medicative Behavior of Wild Chimpanzees in Uganda

P. Grellier, J. Kasenene, Marie-Thérèse Martin, 2004, Antimicrobial Agents and Chemotherapy.

Protist Collections: Essential for Future Research.

J. Votýpka, V. Yurchenko, P. Grellier, 2016, Trends in parasitology.

Bisbenzylisoquinolines as modulators of chloroquine resistance in Plasmodium falciparum and multidrug resistance in tumor cells

F. Calvo, P. Rasoanaivo, P. Grellier, 1996, Antimicrobial agents and chemotherapy.

Antileishmanial and trypanocidal activity of Brazilian Cerrado plants.

L. Espindola, J. Desrivot, A. Fournet, 2005, Memorias do Instituto Oswaldo Cruz.

Chimpanzees in Uganda Survey of Self-Medicative Behavior of Wild Novel Antimalarial Compounds Isolated in a

P. Grellier, Marie-Thérèse Martin, S. Krief, 2014 .

In vitro antiplasmodial activity of Brazilian Cerrado plants used as traditional remedies.

L. Espindola, P. Grellier, M. D. de Mesquita, 2007, Journal of ethnopharmacology.

Antivascular and anti-parasite activities of natural and hemisynthetic flavonoids from New Caledonian Gardenia species (Rubiaceae).

Sylvie Michel, Philippe Grellier, Linh H Mai, 2015, European journal of medicinal chemistry.

Dilobenol A–G, Diprenylated Dihydroflavonols from the Leaves of Dilobeia thouarsii

T. Petit, P. Grellier, A. Deville, 2013 .

Activity of Ocimum basilicum, Ocimum canum, and Cymbopogon citratus essential oils against Plasmodium falciparum and mature-stage larvae of Anopheles funestus s.s.

P. Grellier, E. Mouray, Philippe Belong, 2014, Parasite.

Sesquiterpenoids from Teucrium ramosissimum.

L. Dubost, B. Bodo, P. Grellier, 2009, Phytochemistry.

Replacement of the 4′‐Hydroxy Group of Amodiaquine and Amopyroquine by Aromatic and Aliphatic Substituents: Synthesis and Antimalarial Activity

E. Pǎunescu, P. Melnyk, P. Grellier, 2009, ChemMedChem.

In vitro and in vivo antimalarial properties of isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis.

L. Angenot, Geneviève Philippe, M. Tits, 2004, Planta Medica.

Theionbrunonines A and B: Dimeric Vobasine Alkaloids Tethered by a Thioether Bridge from Mostuea brunonis.

Pierre Champy, Erwan Poupon, Mehdi A Beniddir, 2018, Organic letters.

The Traditional Medicine Spilanthes acmella, and the Alkylamides Spilanthol and Undeca‐2E‐ene‐8,10‐diynoic Acid Isobutylamide, Demonstrate In Vitro and In Vivo Antimalarial Activity

P. Grellier, Kevin Spelman, E. Mouray, 2011, Phytotherapy research : PTR.

ANTIMALARIALS AND ANTIOXIDANTS COMPOUNDS FROM PIPER TRICUSPE (PIPERACEAE)

P. Grellier, B. Figadère, C. Segura, 2008 .

Preparative isolation, fast centrifugal partition chromatography purification and biological activity of cajaflavanone from Derris ferruginea stems.

M. Litaudon, P. Grellier, P. Richomme, 2012, Phytochemical analysis : PCA.

Probiotics for the Control of Parasites: An Overview

P. Grellier, I. Florent, M. Travers, 2011, Journal of parasitology research.

Triterpenes from the exudate of Gardenia urvillei.

V. Dumontet, P. Grellier, E. Prost, 2016, Phytochemistry.

Molecular, functional and structural properties of the prolyl oligopeptidase of Trypanosoma cruzi (POP Tc80), which is required for parasite entry into mammalian cells.

B. Maigret, J. F. da Silveira, N. Martins, 2005, The Biochemical journal.

Analysing ambiguities in trypanosomatids taxonomy by barcoding

R. Helaers, M. Vikkula, P. Grellier, 2020, Memorias do Instituto Oswaldo Cruz.

Bile-Salt-Hydrolases from the Probiotic Strain Lactobacillus johnsonii La1 Mediate Anti-giardial Activity in Vitro and in Vivo

A. Buret, S. Chaouch, P. Langella, 2018, Front. Microbiol..

Biochemical properties and cellular localization of Plasmodium falciparum protein disulfide isomerase.

C. Sergheraert, P. Grellier, M. Moutiez, 2007, Biochimie.

Characterization of a new 60 kDa apical protein of Plasmodium falciparum merozoite expressed in late schizogony

P. Grellier, B. Carcy, E. Précigout, 1994, Biology of the cell.

Bile Salt Hydrolase Activities: A Novel Target to Screen Anti-Giardia Lactobacilli?

S. Chaouch, P. Langella, B. Polack, 2018, Front. Microbiol..

Redescription of Dicyemennea eledones (Wagener, 1857) (Phylum Dicyemida) from Eledone cirrhosa (Lamarck, 1798) (Mollusca: Cephalopoda: Octopoda)

M. Romdhane, H. Furuya, M. Dellinger, 2016, Systematic Parasitology.

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin.

B. Pradines, Sébastien Charneau, W. Charman, 2004, Journal of medicinal chemistry.

Antimalarial Compounds from Traditionally Used Medicinal Plants

P. Grellier, L. Mambu, 2007 .

Calcium in the Backstage of Malaria Parasite Biology

Sébastien Charneau, M. R. Alborghetti, R. Amino, 2021, Frontiers in Cellular and Infection Microbiology.

New ether diglycosides from Matayba guianensis with antiplasmodial activity.

L. Espindola, A. Blond, P. Grellier, 2005, Bioorganic & medicinal chemistry.

evaluation. Characterization of a monoclonal antibody to human proacrosin and its use in acrosomal status

J. Gallo, D. Escalier, P. Grellier, 2011 .

Characterization of a monoclonal antibody to human proacrosin and its use in acrosomal status evaluation.

J. Gallo, D. Escalier, P. Grellier, 1991, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Antiplasmodial activity of quinones: roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase.

H. Nivinskas, N. Čėnas, P. Grellier, 2010, Archives of biochemistry and biophysics.

Antiplasmodial activity of nitroaromatic and quinoidal compounds: redox potential vs. inhibition of erythrocyte glutathione reductase.

N. Čėnas, P. Grellier, Ž. Anusevičius, 2001, Archives of biochemistry and biophysics.

Synthesis of 5-enamine-4-thiazolidinone derivatives with trypanocidal and anticancer activity.

R. Lesyk, A. Gzella, P. Grellier, 2019, Bioorganic chemistry.

Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues.

Philippe Grellier, P. Grellier, E. Mouray, 2010, Bioorganic & medicinal chemistry.

Antimalarial Activity of Axidjiferosides, New β-Galactosylceramides from the African Sponge Axinyssa djiferi

M. Clément, G. Wielgosz-Collin, P. Grellier, 2013, Marine drugs.

Corynanthean-Epicatechin Flavoalkaloids from Corynanthe pachyceras

J. Gallard, M. Beniddir, P. Grellier, 2020, Molecules.

First Draft Genome of the Trypanosomatid Herpetomonas muscarum ingenoplastis through MinION Oxford Nanopore Technology and Illumina Sequencing

B. Bearzatto, R. Helaers, M. Vikkula, 2019, Tropical medicine and infectious disease.

A Plasmodium falciparum FcB1-schizont-EST collection providing clues to schizont specific gene structure and polymorphism

Olivier Gascuel, Laurent Bréhélin, Patrick Wincker, 2009, BMC Genomics.

Synthesis and antimalarial evaluation of a series of piperazinyl flavones.

P. Rasoanaivo, G. Lewin, P. Grellier, 2007, Bioorganic & medicinal chemistry letters.

Comparison of the inhibition of human and Trypanosoma cruzi prolyl endopeptidases.

E. Davioud‐Charvet, C. Sergheraert, P. Grellier, 2002, Bioorganic & medicinal chemistry.

Automated parallel synthesis of a tetrahydroisoquinolin-based library: potential prolyl endopeptidase inhibitors.

E. Davioud‐Charvet, C. Sergheraert, B. Déprez, 1999, Bioorganic & medicinal chemistry letters.

Role of human group IIA secreted phospholipase A2 in malaria pathophysiology: Insights from a transgenic mouse model.

L. Touqui, F. Bihl, G. Lambeau, 2021, Biochimie.

New Approaches to Systematics of Trypanosomatidae: Criteria for Taxonomic (Re)description.

J. Lukeš, D. Maslov, J. Votýpka, 2015, Trends in parasitology.

Selective and reversible effects of vinca alkaloids on Trypanosoma cruzi epimastigote forms: blockage of cytokinesis without inhibition of the organelle duplication.

V. Sinou, P. Grellier, Y. Boulard, 1999, Cell motility and the cytoskeleton.

Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones

D. Smee, R. Lesyk, P. Grellier, 2013, European Journal of Medicinal Chemistry.

Photosensitized Inactivation of Plasmodium falciparum‐ and Babesia divergens‐Infected Erythrocytes in Whole Blood by Lipophilic Pheophorbide Derivatives

V. Agmon, R. Santus, S. Gatt, 1997, Vox sanguinis.

A large multigene family expressed during the erythrocytic schizogony of Plasmodium falciparum.

O. Mercereau‐Puijalon, P. Grellier, T. Fandeur, 1994, Molecular and biochemical parasitology.

New trends in chemotherapy on human and animal blood parasites

R. Santus, V. Sinou, P. Grellier, 1996, Parasitology Research.

Deconjugated Bile Salts Produced by Extracellular Bile-Salt Hydrolase-Like Activities from the Probiotic Lactobacillus johnsonii La1 Inhibit Giardia duodenalis In vitro Growth

Sébastien Charneau, S. Zirah, S. Chaouch, 2016, Front. Microbiol..

Haplomyxa saranae gen. nov. et sp. nov., a new naked freshwater foraminifer.

M. Dellinger, P. Grellier, L. Perrouault, 2014, Protist.

Investigation of anticancer and anti-parasitic activity of thiopyrano[2,3-d]thiazoles bearing norbornane moiety

D. Kaminskyy, R. Lesyk, P. Grellier, 2017 .

Plasmodium Telomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds

Patrizia Alberti, Philippe Grellier, J. Mergny, 2008, Chembiochem : a European journal of chemical biology.

Antimalarial Activity of Human Group IIA Secreted Phospholipase A2 in Relation to Enzymatic Hydrolysis of Oxidized Lipoproteins

G. Lambeau, V. Sinou, D. Parzy, 2019, Infection and Immunity.

In Vitro Anti-Plasmodium falciparum Properties of the Full Set of Human Secreted Phospholipases A2

M. Gelb, G. Lambeau, S. Bezzine, 2015, Infection and Immunity.

Purification and identification of a neutral endopeptidase inPlasmodium falciparum schizonts and merozoites

M. Monsigny, R. Mayer, P. Grellier, 2004, Parasitology Research.

Cloning of Plasmodium falciparum protein disulfide isomerase homologue by affinity purification using the antiplasmodial inhibitor 1,4‐bis{3‐[N‐(cyclohexyl methyl)amino]propyl}piperazine 1

C. Sergheraert, H. Drobecq, P. Grellier, 2000, FEBS letters.

Diarylheptanoid glucosides from Pyrostria major and their antiprotozoal activities

Marc Litaudon, Mehdi A. Beniddir, Françoise Guéritte, 2012 .

Development of Predictive QSAR Models of 4‐Thiazolidinones Antitrypanosomal Activity Using Modern Machine Learning Algorithms

Anna Kryshchyshyn, Oleg Devinyak, Danylo Kaminskyy, 2018, Molecular informatics.

In vitro and in vivo inhibition of erythrocytic development of malarial parasites by docetaxel

V. Sinou, P. Grellier, J. Schrével, 1996, Antimicrobial agents and chemotherapy.

Kinesin 9 family members perform separate functions in the trypanosome flagellum

W. Marande, P. Bastin, P. Grellier, 2009, The Journal of cell biology.

Synthesis and biological activity evaluation of new thiazolidinone-diclofenac hybrid molecules

R. Lesyk, P. Grellier, A. Lozynskyi, 2020 .

Identification and localization of a soluble antigen, Ag2, of 136 kDa from Plasmodium falciparum in vitro cultures

T. Theander, N. Behrendt, M. Torii, 1991, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

RESEARCH ARTICLE Bioactive Properties of Plant Species Ingested by Chimpanzees (Pan troglodytes schweinfurthii) in the Kibale National Park, Uganda

R. Wrangham, M. Huffman, P. Grellier, 2006 .

Synthesis and Antiplasmodial Activity of Novel Fosmidomycin Derivatives and Conjugates with Artemisinin and Aminochloroquinoline

P. Grellier, E. Mouray, M. Baltas, 2020, Molecules.

Prolyl Oligopeptidase From Leishmania infantum: Biochemical Characterization and Involvement in Macrophage Infection

Sébastien Charneau, P. Grellier, C. S. Azevedo, 2020, Frontiers in Microbiology.

Lipid traffic between high density lipoproteins and Plasmodium falciparum-infected red blood cells

V. Clavey, P. Grellier, J. Fruchart, 1991, The Journal of cell biology.

A Protein Phosphatase 1 involved in correct nucleus positioning in trypanosomes.

P. Grellier, L. Kohl, R. Demonchy, 2013, Molecular and biochemical parasitology.

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit in vitro development of Plasmodium falciparum and Babesia divergens in human erythrocytes

P. Grellier, A. Valentin, J. Schrével, 1994, Antimicrobial Agents and Chemotherapy.

Flavonoids from Dalbergia louvelii and their antiplasmodial activity.

P. Rasoanaivo, P. Grellier, D. Ramanitrahasimbola, 2003, Journal of natural products.

Revisiting Previously Investigated Plants: A Molecular Networking-Based Study of Geissospermum laeve.

Marc Litaudon, Pierre Champy, Alexander E Fox Ramos, 2017, Journal of natural products.

Molecular Networking Reveals Serpentinine-Related Bisindole Alkaloids from Picralima nitida, a Previously Well-Investigated Species.

J. Gallard, M. Beniddir, P. Grellier, 2020, Journal of natural products.

Oligopeptidase B, a missing enzyme in mammals and a potential drug target for trypanosomatid diseases.

P. Grellier, C. S. Azevedo, F. N. Motta, 2019, Biochimie.

Discovery of new targets for antimalarial chemotherapy.

P. Grellier, I. Florent, J. Schrével, 2008, Parasite.

Novel N-(4-Piperidinyl)benzamide antimalarials with mammalian protein farnesyltransferase inhibitory activity.

C. Sergheraert, A. Lemoine, N. Pommery, 2005, Chemical & pharmaceutical bulletin.

Parasite Prolyl Oligopeptidases and the Challenge of Designing Chemotherapeuticals for Chagas Disease, Leishmaniasis and African Trypanosomiasis

P. Grellier, J. Santana, I. Bastos, 2013, Current medicinal chemistry.

Dynamic molecular events associated to Plasmodium berghei gametogenesis through proteomic approach.

Marlon D. M. Santos, Sébastien Charneau, P. Carvalho, 2017, Journal of proteomics.

Identification of novel Trypanosoma cruzi prolyl oligopeptidase inhibitors by structure-based virtual screening

Vincent Leroux, Bernard Maigret, Philippe Grellier, 2016, Journal of Computer-Aided Molecular Design.

Design, Synthesis and Antimalarial Activity of Trifluoromethylartemisinin–Mefloquine Dual Molecules

P. Grellier, D. Bonnet-Delpon, J. Bégué, 2005, Chembiochem : a European journal of chemical biology.

Identification of novel Zika virus NS3 protease inhibitors with different inhibition modes by integrative experimental and computational approaches.

J. Barbosa, P. Grellier, B. Sousa, 2023, Biochimie.

Neutral proteases involved in the reinvasion of erythrocytes by Plasmodium merozoites

M. Monsigny, R. Mayer, P. Grellier, 1988, Biology of the cell.

From the Spectroscopic Reassessment of Authentic Alkaloid Samples to the Molecular Networking-Guided Discovery of Criophylline-Related Analogues from Callichilia inaequalis.

S. Agnandji, P. Retailleau, J. Gallard, 2023, Journal of natural products.

Biochemical characterization, localization and immunostimulating properties of a soluble glycoprotein, Ag1, isolated from in vitro cultures ofPlasmodium falciparum

T. Theander, L. Hviid, P. Grellier, 2004, Parasitology Research.

A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline.

R. Schirmer, K. Becker, C. Biot, 2001, Journal of medicinal chemistry.

Synthesis and in vitro antiplasmodial activity of ferrocenyl aminoquinoline derivatives.

Till Bousquet, P. Grellier, E. Mouray, 2015, European journal of medicinal chemistry.

Synthesis of 11-aza-artemisinin derivatives using the Ugi reaction and an evaluation of their antimalarial activity

W. Dehaen, P. Grellier, V. Pham, 2014 .

The Beckmann Rearrangement Applied to Ursolic Acid with Antimalarial Activity in Medicinal Chemistry Studies

G. Gosmann, S. Gnoatto, P. Grellier, 2012 .

Anti-Plasmodium activity of ceramide analogs

Arie Dagan, Shimon Gatt, Philippe Grellier, 2004, Malaria Journal.

Antiplasmodial Phenolic compounds from Piptadenia pervillei

P. Rasoanaivo, P. Grellier, D. Ramanitrahasimbola, 2008, Planta medica.

A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds

M. Litaudon, G. Marti, P. Grellier, 2010, Molecules.

New approaches in in vitro cultures of Plasmodium falciparum and Babesia divergens by using serum-free medium based on human high density lipoproteins.

P. Grellier, J. Schrével, D. Rigomier, 1992, Memorias do Instituto Oswaldo Cruz.

Malaria and obesity: obese mice are resistant to cerebral malaria

C. Bourgouin, V. Robert, P. Grellier, 2008, Malaria Journal.

Synthesis and Antimalarial Activity of Some New 1,2-Dioxolane Derivatives

P. Grellier, P. Richomme, D. Séraphin, 2002, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and antimalarial activity of carbamate and amide derivatives of 4-anilinoquinoline.

C. Sergheraert, L. Maes, P. Melnyk, 2008, European journal of medicinal chemistry.

Synthesis and antimalarial activity of new amino analogues of amodiaquine.

E. Pǎunescu, P. Melnyk, P. Grellier, 2008, Medicinal chemistry (Shariqah (United Arab Emirates)).

Host Cell and Malarial Targets for Docetaxel (Taxotere™) during the Erythrocytic Development of Plasmodium falciparum

V. Sinou, P. Grellier, Y. Boulard, 1998, The Journal of eukaryotic microbiology.

Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity.

S. Croft, A. Lambeir, P. Van der Veken, 2003, Bioorganic & medicinal chemistry letters.

Plasmodium falciparum genes differentially expressed during merozoite morphogenesis.

Philippe Grellier, Sébastien Charneau, P. Grellier, 2004, Molecular and biochemical parasitology.

Antiplasmodial alkaloids from Desmos rostrata.

M. Litaudon, P. Grellier, V. Pham, 2008, Journal of natural products.

Antiplasmodial activity of Uvaria klaineana.

B. Akendengué, E. Ngou-Milama, A. Laurens, 2002, Planta Medica.

Photodecontamination of blood components: advantages and drawbacks.

R. Santus, J. Stoltz, J. Mazière, 1998, Clinical hemorheology and microcirculation.

Ethnopharmacological study of plants used to treat malaria, in traditional medicine, by Bete Populations of Issia (Côte d’Ivoire)

P. Grellier, K. N'guessan, N. Z. Guédé, 2010 .

Anti-Protozoan Activities of Polar Fish-Derived Polyalanine Synthetic Peptides

O. Franco, Sébastien Charneau, M. H. Cardoso, 2023, Marine drugs.

[Effect of serum on the outcome of in vitro testing of the chemosensitivity of Plasmodium falciparum].

A. Djaman, P. Grellier, F. Guede-guina, 2010, Medecine tropicale : revue du Corps de sante colonial.

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

J Mottram, L Meijer, P Grellier, 2000, Chemistry & biology.

Insights into the microRNA landscape of Rhodnius prolixus, a vector of Chagas disease

Sébastien Charneau, S. Chaouch, P. Grellier, 2023, Scientific reports.

Actin in the acrosome of the spermatozoa of the crab, Cancer pagurus L. (decapoda, crustacea)

J. Justine, P. Grellier, C. Tudge, 1994, Molecular reproduction and development.

[In vitro induction of Plasmodium falciparum schizogony by human high density lipoproteins (HDL)].

P. Grellier, J. Schrével, D. Rigomier, 1990, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

Synthesis and antimalarial evaluation of new 1,4-bis(3-aminopropyl)piperazine derivatives.

C. Sergheraert, P. Grellier, R. Deprez-Poulain, 2003, Bioorganic & medicinal chemistry letters.

Aminocyclopropanes as precursors of endoperoxides with antimalarial activity.

P. Retailleau, P. Grellier, I. Florent, 2010, Organic & biomolecular chemistry.

A Photoalkylative Fluorogenic Probe of Guttiferone A for Live Cell Imaging and Proteome Labeling in Plasmodium falciparum

Magali Blaud, Marie-Christine Lallemand, P. Grellier, 2020, Molecules.

Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues

Soizic Prado, P. Grellier, J. Herrmann, 2013, Beilstein journal of organic chemistry.

New synthesis of benzo-delta-carbolines, cryptolepines, and their salts: in vitro cytotoxic, antiplasmodial, and antitrypanosomal activities of delta-carbolines, benzo-delta-carbolines, and cryptolepines.

P. Grellier, F. Marsais, E. Arzel, 2001, Journal of medicinal chemistry.

New Approaches to Systematics of Trypanosomatidae: Criteria for Taxonomic (Re)description.

J. Lukeš, D. Maslov, J. Votýpka, 2015, Trends in parasitology.

Photochemical inactivation with amotosalen and long‐wavelength ultraviolet light of Plasmodium and Babesia in platelet and plasma components

M. Steiert, Sébastien Charneau, H. Gil, 2008, Transfusion.

Evaluation of Nucleoside Hydrolase Inhibitors for Treatment of African Trypanosomiasis

H. D. de Koning, J. Steyaert, M. Degano, 2010, Antimicrobial Agents and Chemotherapy.

In Vitro Anti-Plasmodium falciparum Properties of the Full Set of Human Secreted Phospholipases A2

M. Gelb, G. Lambeau, S. Bezzine, 2015, Infection and Immunity.

Dendropsophin 1, a novel antimicrobial peptide from the skin secretion of the endemic Colombian frog Dendropsophus columbianus

S. M. de Freitas, Sébastien Charneau, P. Grellier, 2018, Natural product research.

The ferroquine antimalarial conundrum: redox activation and reinvasion inhibition.

C. Biot, D. Dive, C. Slomianny, 2013, Angewandte Chemie.

Comparative proteomic analysis of kinesin-8B deficient Plasmodium berghei during gametogenesis.

D. Ferguson, Sébastien Charneau, C. Ricart, 2021, Journal of proteomics.

Synthesis and evaluation of biological activity of rhodanine-pyrazoline hybrid molecules with 2-(2,6-dichlorophenylamino)-phenylacetamide fragment

R. Lesyk, P. Grellier, A. Lozynskyi, 2020, Biopolymers and Cell.

Preliminary evaluation of thiazolidinone- and pyrazoline-related heterocyclic derivatives as potential antimalarial agents

R. Lesyk, P. Grellier, Anna P. Kryshchyshyn-Dylevych, 2020 .

Revealing a Novel Otubain-Like Enzyme from Leishmania infantum with Deubiquitinating Activity toward K48-Linked Substrate

K. Magalhães, P. Grellier, D. Nolasco, 2017, Front. Chem..

Diversity of apostome ciliates, Chromidina spp. (Oligohymenophorea, Opalinopsidae), parasites of cephalopods of the Mediterranean Sea

J. Justine, M. Romdhane, H. Furuya, 2016, Parasite.

Differential actions of antimicrotubular drugs on the development of Trypanosoma cruzi, the agent of Chagas' disease

V. Sinou, P. Grellier, J. Schrével, 1995 .