D. T. Connor

发表

Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.

R. D. Dyer, A. Sercel, K. Chan, 1999, Journal of medicinal chemistry.

R. D. Dyer, A. Sercel, R. Gilbertsen, 1999, Journal of medicinal chemistry.

Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors.

D. Ortwine, D. Flynn, D. T. Connor, 1991, Journal of medicinal chemistry.

Synthesis of the 3a,8a-dihydrofuro[2,3-b]benzofuran-2(3H)-one and 1,3,3a,8a-tetrahydro-2H-benzofuro[2,3-b]pyrrol-2-one ring systems from 4-formylcoumarin via acyllactone and iminolactone rearrangements

D. T. Connor, M. V. Strandtmann, 1973 .

(Aryloxy)alkylamines as selective human dopamine D4 receptor antagonists: potential antipsychotic agents.

T. Heffner, R. Doubleday, D. T. Connor, 1997, Journal of medicinal chemistry.

Synthesis and antiallergy activity of 10-oxo-10H-pyrido[1,2-a]thieno[3,2-d]pyrimidines and 10-oxo-10H-pyrido[1,2-a]thieno[3,4-d]pyrimidines.

R. Sorenson, J. Kerbleski, D. T. Connor, 1984, Journal of medicinal chemistry.

1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.

R. D. Dyer, D. Boschelli, R. Dyer, 1993, Journal of medicinal chemistry.

(S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.

D. T. Connor, B. Roth, J. Schmidt, 2000, Journal of medicinal chemistry.

Synthesis of reversed hydroxamic acids of indomethacin: dual inhibitors of cyclooxygenase and 5-lipoxygenase

R. D. Dyer, D. Boschelli, R. Dyer, 1992 .

Synthesis of pyrimidine analogs of 2,6‐Di‐tert‐butylphenol antiinflammatory agents

D. T. Connor, P. Unangst, C. Kostlan, 1995 .

Synthesis and structure-activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-molecule antagonists for interleukin-8 receptor.

D. T. Connor, B. Roth, S. Qin, 2003, Bioorganic & medicinal chemistry.

The pharmacologic effects of 5-[3,5-bis(1,1-dimethylethyl)-4- hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt (CI-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritation.

R. D. Dyer, M. D. Mullican, R. Dyer, 1994, Prostaglandins.

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)- 4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity.

R. D. Dyer, R. Sorenson, R. Dyer, 1994, Journal of medicinal chemistry.

Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents.

R. D. Dyer, M. D. Mullican, M. Wilson, 1993, Journal of medicinal chemistry.

Synthesis and antiallergy activity of 4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidines.

R. Sorenson, J. Kerbleski, D. T. Connor, 1981, Journal of medicinal chemistry.

Preparation of Benzothieno[2,3-f]-1,4-oxazepin- and -thiazepin-5(2H)-ones and of Benzothieno[3,2-e]-1,4-diazepin-5-ones

D. Boschelli, D. T. Connor, H. Barth, 1996 .

Synthesis and cyclooxygenase and 5-lipoxygenase inhibitory activity of some thiazolidene-4-one analogs of meclofenamic acid

D. Boschelli, D. T. Connor, C. Wright, 1992 .

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors.

R. Dyer, D. T. Connor, P. Unangst, 1992, Journal of medicinal chemistry.

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors.

R. D. Dyer, R. Dyer, D. T. Connor, 1992, Journal of medicinal chemistry.

The reaction of 2-picoline N-Oxide with o-substituled benzoates and lsatoic anhydrides

D. T. Connor, M. V. Strandtmann, P. A. Young, 1977 .

Heterocyclic synthesis with N-oxides. Preparation of pyridine n-oxide substituted chromones, chromanones, coumarins, quinolones, dihydroquinolones and cinnolones

D. T. Connor, M. V. Strandtmann, P. A. Young, 1977 .

Reaction of (carbethoxymethylene)triphenylphosphorane with .omega.-nitrostyrenes and isatoic anhydrides

D. T. Connor, M. V. Strandtmann, 1973 .

Chromeno[3,4-c]pyridin-5-ones: selective human dopamine D4 receptor antagonists as potential antipsychotic agents.

T. Heffner, D. T. Connor, P. Unangst, 1997, Journal of medicinal chemistry.

Novel thiophene-, pyrrole-, furan-, and benzenecarboxamidotetrazoles as potential antiallergy agents.

M. D. Mullican, R. Sorenson, D. T. Connor, 1991, Journal of medicinal chemistry.

Synthesis of 4,10-dihydro-4,10-dioxo-1H-[1]-benzopyrano[3,2-b]pyridine, 4,5-Dihydro-4,5-dioxo-1H-[1]-benzopyrano[2,3–6]pyridine and 1,5-Dihydro-1,5-dioxo-4H-[1]-benzopyrano[3,4-b]pyridine derivatives from aminobenzopyrones

D. T. Connor, P. A. Young, M. V. Strandtmann, 1981 .

Novel indolecarboxamidotetrazoles as potential antiallergy agents.

D. T. Connor, P. Unangst, M. C. Conroy, 1989, Journal of medicinal chemistry.

3-(aminoalkyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c] pyridin-5-ones as potential anticholinergic bronchodilators.

R. Sorenson, D. T. Connor, P. Unangst, 1989, Journal of medicinal chemistry.

Syntheses of 10‐Oxo‐10H‐pyrido[1,2‐a]thieno[3,4‐d]pyrimidines and 10‐Oxo‐10H‐pyrido[1,2‐a]thieno[3,2‐d]pyrimidines from methyl tetrahydro‐4‐oxo‐3‐thiophenecarboxylate and methyl tetrahydro‐3‐oxo‐2‐thiophenecarboxylate, respectively

R. Sorenson, J. Kerbleski, D. T. Connor, 1982 .

Synthesis and Biological Evaluation of 5-((3,5-Bis(1,1-dimethylethyl)- 4-hydroxyphenyl)methylene)oxazoles, -thiazoles, and -imidazoles: Novel Dual 5-Lipoxygenase and Cyclooxygenase Inhibitors with Antiinflammatory Activity.

R. D. Dyer, R. Sorenson, R. Dyer, 1994 .

Oxazole, thiazole, and imidazole derivatives of 2,6-di-tert-butylphenol as dual 5-lipoxygenase and cyclooxygenase inhibitors

R. D. Dyer, R. Sorenson, R. Dyer, 1993 .

Steroid hormones. Part XVI. Some organometallic and 3-deoxysteroids

D. T. Connor, A. Birch, P. Cross, 1966 .

Addition reactions of allyl stannanes to an indolo[2′,3′:3,4]pyrido[1,2-b]isoquinoline imminium salt

J. Rubin, D. T. Connor, P. Unangst, 2000 .

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic Acids. I. Utilization of ullmann and dieckmann reactions for the preparation of 3-hydroxy, 3-alkoxy, and 3-alkyl derivatives

D. T. Connor, P. Unangst, R. Weikert, 1987 .

Correction. W-7783, a Unique Antifungal Antibiotic

D. T. Connor, C. Greenough, Maximilliam von Stradtmann, 1978 .

W-7783, a unique antifungal antibiotic.

D. T. Connor, R. Greenough, M. von Strandtmann, 1977, The Journal of organic chemistry.

Cyclooxygenase and 5-lipoxygenase inhibitory activity of 2,6 di-t-butylphenols linked by a sulfur atom to 1,3,4-thiadiazoles and 1,3,4-oxadiazoles

D. Boschelli, R. Dyer, D. T. Connor, 1993 .

Synthesis of 2,6-di-tert-butylphenols linked to 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

D. Boschelli, D. T. Connor, J. B. Kramer, 1994 .

Styrylpyrazoles, Styrylisoxazoles, and Styrylisothiazoles. Novel 5‐ Lipoxygenase and Cyclooxygenase Inhibitors.

D. Ortwine, D. Flynn, D. T. Connor, 1991 .

Antifungal agents. 4. Chemical modification of antibiotics from Polyangium cellulosum var. fulvum. Ester and amide analogues of ambruticin.

D. T. Connor, M. von Strandtmann, 1979, Journal of medicinal chemistry.

Inhibition of E-selectin-, ICAM-1-, and VCAM-1-mediated cell adhesion by benzo[b]thiophene-, benzofuran-, indole-, and naphthalene-2-carboxamides: identification of PD 144795 as an antiinflammatory agent.

D. Boschelli, R. Sorenson, D. T. Connor, 1995, Journal of medicinal chemistry.

Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents.

M. D. Mullican, R. Sorenson, D. T. Connor, 1992, Journal of medicinal chemistry.

Synthesis of novel 5-hydroxy-3-alkoxy- and 5-hydroxy-3-alkylthioindole-2-carboxamides

D. T. Connor, P. Unangst, S. Miller, 1996 .

Synthesis of Novel 5-Hydroxy-3-alkoxy- and 5-Hydroxy-3-alkylthioindole- 2-carboxamides.

D. T. Connor, P. Unangst, S. Miller, 1997 .

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic acids. II. Preparation of 3-dialkylamino, 3-alkylthio, 3-alkylsulfinyl, and 3-alkylsulfonyl derivatives

D. T. Connor, P. Unangst, S. R. Stabler, 1987 .

3-Alkoxybenzo[b]thiophene-2-carboxamides as inhibitors of neutrophil-endothelial cell adhesion.

D. Boschelli, D. T. Connor, D. Schrier, 1994, Journal of medicinal chemistry.

Inhibition of adhesion molecule expression by N-alkylthiopyridine-benzo[b]thiophene-2-carboxamides.

D. Boschelli, D. T. Connor, D. Schrier, 1996, Bioorganic & medicinal chemistry.

Preparation of novel 1,2,4-thiadiazoles by cyclization with 4-methylbenzenesulfonyl cyanide (tosyl cyanide)

D. T. Connor, P. Unangst, G. Shrum, 1993 .

Synthesis and transformations of 2,6-bis(1,1-dimethylethyl)-4-[2-(thiazolyl)ethenyl]phenols

D. T. Connor, P. Unangst, 1992 .

Synthesis and Transformations of 2,6-Bis(1,1-dimethylethyl)-4-(2-( thiazolyl)ethenyl)phenols.

D. T. Connor, P. Unangst, 1993 .

Preparation of Novel 1,2,4-Thiadiazoles by Cyclization with 4- Methylbenzenesulfonyl Cyanide (Tosyl Cyanide).

D. T. Connor, P. Unangst, G. Shrum, 2010 .

R. D. Dyer, A. Sercel, K. Chan, 1999, Journal of medicinal chemistry.

Inhibition of E-Selectin-, ICAM-1, and VCAM-1-Mediated Cell Adhesion by Benzo(b)thiophene-, Benzofuran-, Indole-, and Naphthalene-2- carboxamides: Identification of PD 144795 as an Antiinflammatory Agent.

D. Boschelli, R. Sorenson, D. T. Connor, 1996 .

Sympathetic nervous system activity snsa in hypertension are there racial differences

D. T. Connor, O. apos, R. Parmer, 1987 .

Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase

D. Boschelli, R. Dyer, D. T. Connor, 1992 .

Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase.

R. D. Dyer, R. Dyer, D. Flynn, 1990, Journal of medicinal chemistry.