J. Quiroga

发表

Synthesis and antifungal evaluation of novel dicyanoderivatives of rhodanine

M. Derita, B. Insuasty, Alberto Insuasty, 2011 .

Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones

B. Insuasty, Alberto Insuasty, J. Quiroga, 2013, Molecules.

Synthesis and study of the electronic properties of pyrazolo[1,5-c]pyrrolo[1,2-a]quinazoline and pyrazolo[1,5-c]pyrido[1,2-a]quinazoline derivatives

B. Insuasty, J. Quiroga, R. Abonía, 2017, Monatshefte für Chemie - Chemical Monthly.

Synthesis and characterization of Cu(I) and Zn(II) complexes with new sulfur-bearing isoxazole- or pyrazole-based ligands

B. Insuasty, J. Quiroga, V. Landaeta, 2015 .

Three-component one-pot synthesis of new spiro[indoline-pyrrolidine] derivatives mediated by 1,3-dipolar reaction and DFT analysis

B. Insuasty, J. Quiroga, R. Abonía, 2021, Monatshefte für Chemie - Chemical Monthly.

(5RS)-6H-Spiro[pyrazolo[1,5-c]quinazoline-5,4'-thiochroman]: efficient synthesis under mild conditions, molecular structure and supramolecular assembly.

C. Glidewell, J. Quiroga, J. Cobo, 2015, Acta crystallographica. Section C, Structural chemistry.

Synthesis and spectroscopic and structural characterization of spiro[indoline-3,3′-indolizine]s formed by 1,3-dipolar cycloadditions between isatins, pipecolic acid and an electron-deficient alkene

C. Glidewell, J. Quiroga, J. Cobo, 2021, Acta crystallographica. Section C, Structural chemistry.

Two methyl 3-(1H-pyrazol-4-yl)octahydropyrrolo[3,4-c]pyrrole-1-carboxylates form different hydrogen-bonded sheets.

C. Glidewell, J. Quiroga, J. Cobo, 2013, Acta crystallographica. Section C, Crystal structure communications.

An efficient two-step synthesis of novel 2-amino-substituted pyrazolo[1,5-a][1,3,5]triazines

E. Castro, B. Insuasty, J. Quiroga, 2013 .

Solvent‐Free Microwave‐Assisted Synthesis of Novel 4‐Hetarylpyrazolo[1,5‐a][1,3,5]triazines

B. Insuasty, J. Quiroga, R. Abonía, 2012 .

Three practical approaches for the synthesis of novel 4,7-dihetarylpyrazolo[1,5-a] [1,3,5] triazines

E. Castro, B. Insuasty, J. Quiroga, 2012 .

Synthesis of 3-aryl-1,2,4-benzotriazines via intramolecular cyclization of solid-supported o-hydrazidoanilines

B. Insuasty, J. Quiroga, R. Abonía, 2012, Molecular Diversity.

Synthesis and antifungal activity of (Z)-5-arylidenerhodanines.

R. Enriz, B. Insuasty, J. Quiroga, 2007, Bioorganic & medicinal chemistry.

Prediction of the potential biological activity of novel spiropyrazolo[3,4-b]pyridines and spiropyrazolo[3,4-b]pyridine-5,5'-pyrimidines by a ligand-protein inverse-docking approach.

J. Olivero-Verbel, J. Quiroga, P. Romo, 2020, Journal of molecular graphics & modelling.

Regio- and stereospecific assembly of dispiro[indoline-3,3′-pyrrolizine-1′,5′′-thiazolidines] from simple precursors using a one-pot procedure: synthesis, spectroscopic and structural characterization, and a proposed mechanism of formation

C. Glidewell, J. Quiroga, J. Cobo, 2020, Acta crystallographica. Section C, Structural chemistry.

N6-substituted 2-amino-4-chloro-5-formylpyrimidines: puckered versus planar pyrimidine rings, and hydrogen-bonded aggregation in zero, one, two and three dimensions.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section B, Structural science.

4-(4-Chlorophenyl)-3,7,7-trimethyl-1-[2-(4-nitrobenzoyl)ethyl]-4,7,8,9-tetrahydro-1H-pyrazolo[3,4-b]quinolin-5(6H)-one-ethanol (1/1).

J. N. Low, J. Quiroga, M. Nogueras, 2001, Acta crystallographica. Section C, Crystal structure communications.

Microwave-Assisted Synthesis under Solvent-Free Conditions of (E)-2-(Benzo(d)thiazol-2-yl)-3-arylacrylonitriles

J. Quiroga, A. Ortíz, Jorge Trilleras, 2011 .

Synthesis of novel 7-aryl and 7-spiropyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidine derivatives and their study as AChE inhibitors

Margarita Gutiérrez, B. Insuasty, J. Quiroga, 2017, Molecular Diversity.

Synthesis, structures, electrochemical studies and antioxidant activity of 5-aryl-4-oxo-3,4,5,8-tetrahydropyrido[2,3-d]pyrimidine-7-carboxylic acids

B. Insuasty, J. Quiroga, R. Abonía, 2016 .

(E)-3-tert-butyl-4-(4-chlorobenzyl)-N-(4-chlorobenzylidene)-1-phenyl-1H-pyrazol-5-amine: sheets built from π-stacked hydrogen-bonded dimers.

C. Glidewell, J. Quiroga, J. Cobo, 2013, Acta crystallographica. Section C, Crystal structure communications.

Hydrogen-bonded bilayers in 7-benzyl-3-tert-butyl-1-phenyl-4,5,6,7-tetrahydro-1H-spiro[pyrazolo[3,4-b]pyridine-5,2'-indan]-1',3'-dione.

C. Glidewell, J. Quiroga, J. Cobo, 2013, Acta crystallographica. Section C, Crystal structure communications.

A simple hydrogen-bonded chain in (3Z)-3-{1-[(5-phenyl-1H-pyrazol-3-yl)amino]ethylidene}-4,5-dihydrofuran-2(3H)-one, and a hydrogen-bonded ribbon of centrosymmetric rings in the self-assembled adduct (3Z)-3-{1-[(5-methyl-1H-pyrazol-3-yl)amino]ethylidene}-4,5-dihydrofuran-2(3H)-one-6-(2-hydroxyethyl)

C. Glidewell, J. Quiroga, J. Cobo, 2010, Acta crystallographica. Section C, Crystal structure communications.

2-Cyano-N-(2,6-dimethoxypyrimidin-4-yl)-3-[4-(dimethylamino)phenyl]acrylamide and dimethylammonium 6-cyano-1,3-dimethyl-2,4,5-trioxo-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidin-8-ide: a pi-stacked dimer and a hydrogen-bonded ribbon containing three types of ring.

C. Glidewell, M. Hursthouse, J. Quiroga, 2010, Acta crystallographica. Section C, Crystal structure communications.

2-Cyano-N-(4,6-dimethoxypyrimidin-2-yl)acetamide: complex sheets built from N-H...O and C-H...O hydrogen bonds.

C. Glidewell, J. Quiroga, J. Cobo, 2010, Acta crystallographica. Section C, Crystal structure communications.

5-Amino-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde hemihydrate: a polarized electronic structure within hydrogen-bonded sheets of R(10)(8)(34) rings.

C. Glidewell, J. Quiroga, J. Cobo, 2010, Acta crystallographica. Section C, Crystal structure communications.

4-(2-Fluorophenyl)-6-(1H-indol-1-yl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile: a chain of rings built from N-H...N, C-H...N and C-H...pi(arene) hydrogen bonds.

C. Glidewell, J. Quiroga, J. Cobo, 2009, Acta crystallographica. Section C, Crystal structure communications.

2-Amino-4-chloro-5-formyl-6-[methyl(2-methylphenyl)amino]pyrimidine and 2-amino-4-chloro-5-formyl-6-[(2-methoxyphenyl)methylamino]pyrimidine are isostructural and form hydrogen-bonded sheets of R2(2)8 and R6(6)32 rings.

C. Glidewell, J. Quiroga, J. Cobo, 2009, Acta crystallographica. Section C, Crystal structure communications.

N(4)-Methyl-N(4)-(2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine-ethanol-hydrazine (1/0.865/0.135): hydrogen-bonded ribbons containing four independent ring types.

C. Glidewell, J. Quiroga, J. Cobo, 2009, Acta crystallographica. Section C, Crystal structure communications.

Four 7-aryl-substituted pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones: similar molecular structures but different crystal structures.

C. Glidewell, M. Hursthouse, J. Quiroga, 2009, Acta crystallographica. Section C, Crystal structure communications.

Anhydrous versus hydrated N4-substituted 1H-pyrazolo[3,4-d]pyrimidine-4,6-diamines: hydrogen bonding in two and three dimensions.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section B, Structural science.

2-(4-chlorophenyl)-5-(4-nitrophenyl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3,6-dicarbaldehyde: a chain of rings built from N-H...O and C-H...O hydrogen bonds.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section C, Crystal structure communications.

(E)-3-Dimethylamino-2-(1H-indol-3-ylcarbonyl)acrylonitrile: a chain of edge-fused rings built from a three-centre N-H...(N,O) hydrogen bond.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section C, Crystal structure communications.

Four N(7)-alkoxybenzyl-substituted 4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridine-5-spiro-1'-cyclohexane-2',6'-diones: hydrogen-bonded supramolecular structures in zero, one, two or three dimensions.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section C, Crystal structure communications.

9-Benzoyl-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8-octahydroxanthene-1,8-dione: molecular conformation and supramolecular aggregation in xanthenediones.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section C, Crystal structure communications.

A hydrogen-bonded chain of rings in 5-amino-1-(4-methoxybenzoyl)-3-methylpyrazole and a three-dimensional hydrogen-bonded framework in 5-amino-3-methyl-1-(2-nitrobenzoyl)pyrazole.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section C, Crystal structure communications.

10-Ethyl-4-oxo-2,3,4,10-tetrahydropyrimido[4,5-b]quinolin-2-iminium 4-toluenesulfonate: a polarized electronic structure in the cation and a hydrogen-bonded sheet structure.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section C, Crystal structure communications.

2,5-Dimethyl-6,7-dihydrobenzo[h]pyrazolo[1,5-a]quinazoline and 2-tert-butyl-5-methyl-6,7-dihydrobenzo[h]pyrazolo[1,5-a]quinazoline.

J. N. Low, C. Glidewell, J. Quiroga, 2007, Acta crystallographica. Section C, Crystal structure communications.

(E)-3-{2-amino-4-ethoxy-6-[N-(4-methoxyphenyl)-N-methylamino]pyrimidin-5-yl}-1-phenylprop-2-en-1-one: a boat-shaped pyrimidine ring and a chain of hydrogen-bonded R4(2)(8) and R2(2)(20) rings.

J. N. Low, C. Glidewell, J. Quiroga, 2007, Acta crystallographica. Section C, Crystal structure communications.

3-(3-Oxo-1,3-dihydroisobenzofuran-1-ylidene)pentane-2,4-dione.

J. N. Low, C. Glidewell, J. Quiroga, 2007, Acta crystallographica. Section C, Crystal structure communications.

8‐tert‐Butyl‐7,10‐diphenyl‐6,10‐dihydro‐5H‐benzo[h]pyrazolo[3,4‐b]quinoline

J. N. Low, C. Glidewell, J. Quiroga, 2007 .

8-tert-Butyl-7-(4-chlorophenyl)-10-phenyl-5,6-dihydro-10H-benzo[h]pyrazolo[3,4-b]quinoline.

J. N. Low, C. Glidewell, J. Quiroga, 2007, Acta crystallographica. Section C, Crystal structure communications.

3-tert-Butyl-1-(4-chlorophenyl)-7,7-dimethyl-5,6,7,8-tetrahydropyrazolo[3,4-b]quinolin-5-one: centrosymmetric dimers generated by C—H⋯π(arene) hydrogen bonds

J. N. Low, C. Glidewell, J. Quiroga, 2005 .

Antimycobacterial Activity of Pyrimido[4,5‐b]diazepine Derivatives

B. Insuasty, J. Quiroga, R. Abonía, 2012, Archiv der Pharmazie.

(E)-3-(4-methylphenyl)-2-(2-thienyl)acrylonitrile has Z' = 0.75 in the space group C2/m: fourfold disordered molecules lie in channels enclosed by fully ordered molecules.

C. Glidewell, J. Quiroga, J. Cobo, 2009, Acta crystallographica. Section C, Crystal structure communications.

SYNTHESIS, MOLECULAR STRUCTURE AND TAUTOMERISM OF 1(2)H-DIHYDROPYRAZOLO[3,4-b]PYRIDIN-6-ONES

J. Elguero, B. Insuasty, J. Quiroga, 1999 .

Synthesis of pyrazolo[3,4-b]azepines and their antioxidant and antibacterial studies

B. Insuasty, J. Quiroga, R. Abonía, 2019, Monatshefte für Chemie - Chemical Monthly.

Catalyst-free three-component synthesis of new pyrrolidine derivatives via 1,3-dipolar cycloaddition

B. Insuasty, J. Quiroga, R. Abonía, 2019, Chemistry of Heterocyclic Compounds.

Time-Efficient Synthesis of Pyrido[2,3-d]pyrimidinones via α-Oxoketenes

J. Quiroga, Jean Rodriguez, Yoann Coquerel, 2016 .

The Aryne aza-Diels-Alder Reaction: Flexible Syntheses of Isoquinolines.

J. Quiroga, R. Abonía, Jean Rodriguez, 2015, Organic letters.

Catalyst-, solvent- and desiccant-free three-component synthesis of novel C-2,N-3 disubstituted thiazolidin-4-ones

B. Insuasty, J. Quiroga, R. Abonía, 2016, Arabian Journal of Chemistry.

Efficient MW-Assisted Synthesis, Spectroscopic Characterization, X-ray and Antioxidant Properties of Indazole Derivatives

Margarita Gutiérrez, J. Quiroga, Jorge Trilleras, 2016, Molecules.

Synthesis and study of fluorescence properties of novel pyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidin-5(6H)-one derivatives

B. Insuasty, J. Quiroga, R. Abonía, 2015 .

Ultrasound-assisted phase-transfer catalysis method in an aqueous medium to promote the Knoevenagel reaction: advantages over the conventional and microwave-assisted solvent-free/catalyst-free method.

Jans H. Alzate-Morales, Julio Caballero, Margarita Gutiérrez, 2014, Ultrasonics sonochemistry.

10-(4-Chlorophenyl)-7-methyl-5,6-dihydrobenzo[h]pyrazolo[5,1-b]quinazoline and 2-(4-chlorophenyl)-5-methyl-6,7-dihydrobenzo[h]pyrazolo[1,5-a]quinazoline: isomeric molecules linked into hydrogen-bonded dimers or pi-stacked chains.

J. N. Low, C. Glidewell, J. Quiroga, 2004, Acta crystallographica. Section C, Crystal structure communications.

SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIFUNGAL EVALUATION OF TETRAHYDROPYRAZOLO[1,5-c]QUINAZOLINES

J. N. Low, B. Insuasty, J. Quiroga, 2003 .

Microwave induced synthesis of novel 8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepines as potential antitumor agents.

B. Insuasty, J. Quiroga, R. Abonía, 2008, European journal of medicinal chemistry.

New aspects on the selective synthesis of 7-arylpyrido[2,3-d]pyrimidines

B. Insuasty, J. Quiroga, R. Abonía, 2002 .

UNEXPECTED SYNTHESIS OF 4-R-PHENYLALLYLIDENE MELDRUM'S ACID DERIVATIVES

J. N. Low, B. Insuasty, J. Quiroga, 2005 .

Reaction of 5-amino-1-aryl-3-methylpyrazoles with benzylidene derivatives of meldrum's acid: Synthesis and characterization of pyrazolo[3,4-b]pyridinones

B. Insuasty, J. Quiroga, A. Hormaza, 1998 .

Synthesis of pyrido[2,3-d]pyrimidinones by the reaction of aminopyrimidin-4-ones with benzylidene meldrum's acid derivatives

B. Insuasty, J. Quiroga, M. Nogueras, 1997 .

Synthesis of pyrido[2,3‐d]pyrimidines in the reaction of 6‐amino‐2,3‐dihydro‐2‐thioxo‐4(1H)‐pyrimidinone with chalcones

B. Insuasty, J. Quiroga, M. Nogueras, 1992 .

Design and synthesis of novel benzopyrazolodiazepinones via intra-molecular alkylation of α-alkylcarbonyl radicals mediated by dilauroylperoxide

B. Insuasty, J. Quiroga, R. Abonía, 2011 .

Microwave-assisted synthesis of pyrimido[4,5-b][1,6]naphthyridin-4(3H)-ones with potential antitumor activity.

B. Insuasty, J. Quiroga, R. Abonía, 2013, European journal of medicinal chemistry.

Synthesis of pyrazolo[1,5-a]pyrimidines in the reaction of 5-amino-3-arylpyrazoles with methoxymethylene meldrum's acid derivatives and thermolysis of their pyrazolylaminomethylene derivatives

B. Insuasty, J. Quiroga, Á. Cañete, 1998 .

A novel product from the reaction of 6-aminopyrimidines and 3-formylchromone

B. Insuasty, J. Quiroga, R. Abonía, 2002 .

Synthesis of novel 1,2,5-trisubstituted benzimidazoles as potential antitumor agents.

B. Insuasty, J. Quiroga, R. Abonía, 2011, European journal of medicinal chemistry.

Regioselective synthesis of 4,7,8,9-tetrahydro-2 H -pyrazolo[3,4- b ]quinolin-5(6 H )-ones. Mechanism and structural analysis

J. N. Low, B. Insuasty, J. Quiroga, 2001 .

Synthesis of 4‐aryl‐4,7,8,9‐tetrahydro‐6H‐pyrazolo[3,4‐b]quinolin‐5‐ones

B. Insuasty, J. Quiroga, C. Saitz, 1998 .

SYNTHESIS OF PYRIMIDO4,5-BQUINOLINES IN THE REACTION OF 6-AMINOPYRIMIDINESWITH DIMEDONE AND BENZALDEHYDES

B. Insuasty, J. Quiroga, M. Nogueras, 1998 .

Regioselective synthesis of fused benzopyrazolo[3,4-b]quinolines under solvent-free conditions

B. Insuasty, J. Quiroga, R. Abonía, 2007 .

Control of the reaction between 2-aminobenzothiazoles and Mannich bases. Synthesis of pyrido[2,1-b][1,3]benzothiazoles versus [1,3]benzothiazolo[2,3-b]quinazolines

J. N. Low, B. Insuasty, J. Quiroga, 2002 .

Microwave‐assisted three‐component synthesis and in vitro antifungal evaluation of 6‐cyano‐5,8‐dihydropyrido[2,3‐d]pyrimidin‐4(3H)‐ones

B. Insuasty, J. Quiroga, R. Abonía, 2006 .

An efficient synthesis of pyrazolo[3,4-b]pyridine-4-spiroindolinones by a three-component reaction of 5-aminopyrazoles, isatin, and cyclic β-diketones

Alfredo Perez, B. Insuasty, J. Quiroga, 2011 .

Microwave-assisted synthesis of pyrazolo[3,4-b]pyridine-spirocycloalkanediones by three-component reaction of 5-aminopyrazole derivatives, paraformaldehyde and cyclic β-diketones

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

Comparison of divergent vs. convergent approaches for solid-phase synthesis of methylenedioxychalcones

B. Insuasty, J. Quiroga, R. Abonía, 2007 .

Solvent‐free microwave multicomponent regiospecific synthesis of pyrimido[4,5‐c]isoquinolines and evaluation In Vitro of their antifungal properties

B. Insuasty, J. Quiroga, R. Abonía, 2006 .

Synthesis of spiro[indoline-3,3'-pyrrolizines] by 1,3-dipolar reactions between isatins, L-proline and electron-deficient alkenes.

C. Glidewell, J. Quiroga, J. Cobo, 2017, Acta crystallographica. Section C, Structural chemistry.

Microwave induced three-component synthesis and antimycobacterial activity of benzopyrazolo[3,4-b]quinolindiones.

B. Insuasty, J. Quiroga, R. Abonía, 2014, European journal of medicinal chemistry.

Regioselective synthesis of fused pyrazolo[1,5-a]pyrimidines by reaction of 5-amino-1H-pyrazoles and β-dicarbonyl compounds containing five-membered rings

J. Quiroga, M. Nogueras, J. Cobo, 2012 .

Catalyst free three-component synthesis of (±)-pyrazolylpyrrolopyrroles by 1,3-dipolar cycloaddition reaction

Alfredo Perez, B. Insuasty, J. Quiroga, 2011 .

Synthesis of novel 6,6a,7,8-tetrahydro-5H-naphtho[1,2-e]pyrimido[4,5-b][1,4]diazepines under microwave irradiation as potential anti-tumor agents.

B. Insuasty, J. Quiroga, R. Abonía, 2010, European journal of medicinal chemistry.

A straightforward synthesis of pyrimido[4,5-b]quinoline derivatives assisted by microwave irradiation

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

Regioselective synthesis of novel substituted pyrazolo[1,5-a]pyrimidines under solvent-free conditions

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Synthesis of novel 5-amino-1-aroylpyrazoles

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Regioselective three-component synthesis of novel indeno[1,2-b]-pyrazolo[4,3-e]pyridines-fused derivatives of 4-azafluorenone alkaloid

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Regioselective synthesis of novel polyfunctionally substituted pyrazolo[1,5-a]pyrimidines under solvent-free conditions

B. Insuasty, J. Quiroga, R. Abonía, 2007 .

Regioselective Synthesis of Fused Benzopyrazolo[3,4‐b]quinolines under Solvent‐Free Conditions.

B. Insuasty, J. Quiroga, R. Abonía, 2007 .

Effect of substitution on the dimensionality of supramolecular aggregation in dihydrobenzopyrazoloquinolines.

J. N. Low, C. Glidewell, J. Quiroga, 2005, Acta crystallographica. Section C, Crystal structure communications.

Solvent-free microwave synthesis of bis-pyrazolo[3,4- b :4′,3′- e ]-pyridines and study of their antifungal properties

B. Insuasty, J. Quiroga, R. Abonía, 2005 .

Solvent-free microwave-assisted synthesis of novel pyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidines with potential antifungal activity

B. Insuasty, J. Quiroga, R. Abonía, 2016 .

5-Cyanoacetylpyrimidines as intermediates for 7-aryl-6-cyanopyrido[2,3-d]pyrimidin-5-ones

B. Insuasty, J. Quiroga, R. Abonía, 2009 .

Three-component synthesis of hexahydropyridopyrimidine–spirocyclohexanetriones induced by microwave

B. Insuasty, J. Quiroga, R. Abonía, 2006 .

Control of the Reaction Between 2‐Aminobenzothiazoles and Mannich Bases. Synthesis of Pyrido[2,1‐b][1,3]benzothiazoles versus [1,3]Benzothiazolo[2,3‐b]quinazolines.

J. N. Low, B. Insuasty, J. Quiroga, 2002 .

Synthesis, characterization and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 5‐aryl‐2‐phenyl‐6,7‐dihydropyrazolo[1,5‐a]pyrimidines

D. Gamenara, B. Insuasty, J. Quiroga, 1999 .

Reaction of 5-aminopyrazoles with β-dimethylaminopropiophenones. Synthesis of new pyrazolo[3,4-b]pyridines

B. Insuasty, J. Quiroga, P. Hernández, 1998 .

The formation of pyrazolo[1,5-a]pyrimidines by the reaction of 3-(4-chlorophenyl)pyrazol-5-amine with chalcones

B. Insuasty, J. Quiroga, H. Meier, 1994 .

ONE-STEP MULTICOMPONENT SYNTHESIS OF 4-AMINO-2-ARYL-3-CYANO-U-DIHYDROPYRIMIDO[1,2-A]BENZIMIDAZOLES

B. Insuasty, J. Quiroga, R. Abonía, 2002 .

Application of catalyst-free Domino Mannich/Freidel-Crafts alkylation reaction for the synthesis of novel tetrahydroquinolines of potential antitumor activity

B. Insuasty, J. Quiroga, R. Abonía, 2018 .

Synthesis of novel hydropyrazolopyridine derivatives in solvent-free conditions via benzotriazole methodology

B. Insuasty, J. Quiroga, R. Abonía, 2004 .

An unexpected chemical behavior of 5-N-(benzotriazol-1-ylmethyl)amino-3-tert-butyl-1-phenylpyrazole

J. N. Low, B. Insuasty, J. Quiroga, 2002 .

Synthesis and structural analysis of 5‐cyanodihydropyrazolo[3,4‐b]pyridines

J. N. Low, B. Insuasty, J. Quiroga, 2001 .

Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor agents.

B. Insuasty, Alexis Tigreros, J. Quiroga, 2010, Bioorganic & medicinal chemistry.

6-(4-Amino-1-methyl-2-(methylthio)-6-oxo-1,6-dihydro-pyrimidin-5-yl)-3,6-dimethyl-2-(methylthio)-6,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-4,5-dione

B. Insuasty, J. Quiroga, M. Nogueras, 2015 .

Fungicide Activity of 5-(4-Chlorobenzylidene)-(Z)-2-dimethylamino-1,3-thiazol-4-one Against Cryptococcus neoformans.

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

Fungicide Activity of 5‐(4‐Chlorobenzylidene)‐(Z)‐2‐dimethylamino‐1,3‐thiazol‐4‐one against Cryptococcus Neoformans

B. Insuasty, J. Quiroga, R. Abonía, 2009, Archiv der Pharmazie.

Synthesis of new indeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-diones as potential antitumor agents.

M. Hursthouse, B. Insuasty, J. Quiroga, 2008, Bioorganic & medicinal chemistry.

Synthesis of 3-Aroyl-4-heteroarylpyrrole Derivatives by the Van Leusen Method

J. Quiroga, Jorge Trilleras, A. Hormaza, 2022, Molbank.

Efficient microwave-assisted synthesis and antitumor activity of novel 4,4'-methylenebis[2-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)phenols].

B. Insuasty, J. Quiroga, R. Abonía, 2011, European journal of medicinal chemistry.

Microwave-assisted one-pot synthesis in water of carbonylpyrazolo[3,4-b]pyridine derivatives catalyzed by InCl3 and sonochemical assisted condensation with aldehydes to obtain new chalcone derivatives containing the pyrazolopyridinic moiety

Margarita Gutiérrez, J. Quiroga, Jorge Trilleras, 2017 .

Synthesis of novel quinoline-2-one based chalcones of potential anti-tumor activity.

B. Insuasty, J. Quiroga, R. Abonía, 2012, European journal of medicinal chemistry.

SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIFUNGAL EVALUATION OF NOVEL BENZIMIDAZO[1,2-c]QUINAZOLINES

B. Insuasty, J. Quiroga, R. Abonía, 2006 .

Regioselective formylation of pyrazolo[3,4-b]pyridine and pyrazolo[1,5-a]pyrimidine systems using Vilsmeier–Haack conditions

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

An efficient synthesis of new caffeine-based chalcones, pyrazolines and pyrazolo[3,4-b][1,4]diazepines as potential antimalarial, antitrypanosomal and antileishmanial agents.

S. Robledo, I. Velez, B. Insuasty, 2015, European journal of medicinal chemistry.

A Schmidt rearrangement-mediated synthesis of novel tetrahydro-benzo[1,4]diazepin-5-ones as potential anticancer and antiprotozoal agents.

S. Robledo, I. Velez, B. Insuasty, 2017, European journal of medicinal chemistry.

Synthesis of novel thiazole-based 8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepines as potential antitumor and antifungal agents.

B. Insuasty, J. Quiroga, R. Abonía, 2015, European journal of medicinal chemistry.

Divergent chemo-, regio-, and diastereoselective normal electron-demand Povarov-type reactions with α-oxo-ketene dienophiles.

J. Quiroga, Jean Rodriguez, Yoann Coquerel, 2014, Organic letters.

Preparation of some light-sensitive 2-nitrophenyl-2,3-dihydro-1H-benzodiazepines

B. Insuasty, J. Quiroga, R. Abonía, 2004 .

Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl)amino]chalcones and hydrazine as potential antitumor and antimalarial agents.

S. Robledo, I. Velez, B. Insuasty, 2013, European journal of medicinal chemistry.

Microwave-Assisted Synthesis of Diversely Substituted Quinoline-Based Dihydropyridopyrimidine and Dihydropyrazolopyridine Hybrids.

K. Laali, B. Insuasty, J. Quiroga, 2017, ACS combinatorial science.

Three-component one-pot synthesis of novel pyrido[2,3-d]pyrimidine indole substituted derivatives and DFT analysis

W. Vallejo, X. Zarate, Carlos Díaz-Uribe, 2017 .

Generation of pyrrolo[2,3-d]pyrimidines. Unexpected products in the multicomponent reaction of 6-aminopyrimidines, dimedone, and arylglyoxal

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

Catalyst-free assembly of giant tris(heteroaryl)methanes: synthesis of novel pharmacophoric triads and model sterically crowded tris(heteroaryl/aryl)methyl cation salts

Gabriela L. Borosky, K. Laali, B. Insuasty, 2019, Beilstein journal of organic chemistry.

Computational and Experimental Study on Molecular Structure of Benzo[g]pyrimido[4,5-b]quinoline Derivatives: Preference of Linear over the Angular Isomer

J. Quiroga, M. Nogueras, J. Cobo, 2017 .

Efficient Microwave-Assisted Synthesis of 5-Deazaflavine Derivatives

J. Quiroga, M. Nogueras, J. Cobo, 2010, Molecules.

Ultrasonics Promoted Synthesis of 5-(Pyrazol-4-yl)-4,5-Dihydropyrazoles Derivatives

J. Quiroga, M. Nogueras, J. Cobo, 2013 .

3′-Methyl-2-oxo-1′,5′-diphenyl-1′,7′-dihydrospiro[indoline-3,4′-pyrazolo[3,4-b]pyridine]-6′-carboxylic Acid

B. Insuasty, J. Quiroga, R. Abonía, 2021, Molbank.

5-[(Dimethylamino)methyleneamino]-3-methyl-1-phenylpyrazole

B. Insuasty, J. Quiroga, R. Moreno-Fuquen, 1999 .

Synthesis and Antifungal in Vitro Evaluation of Pyrazolo[3,4-b]pyridines Derivatives Obtained by Aza-Diels-Alder Reaction and Microwave Irradiation.

B. Insuasty, J. Quiroga, R. Abonía, 2017, Chemical & pharmaceutical bulletin.

Microwave-assisted and iodine mediated synthesis of 5-n-alkyl-cycloalkane[d]-pyrazolo[3,4-b]pyridines from 5-aminopyrazoles and cyclic ketones

B. Insuasty, J. Quiroga, R. Abonía, 2014 .

Microwave-assisted synthesis of fused pyrazolo[3,4-b]pyrazines by the reaction of ortho-aminonitrosopyrazoles and cyclic β-diketones

B. Insuasty, J. Quiroga, R. Abonía, 2012 .

Microwave-Assisted Synthesis of Pyrazolo[3,4-b]pyridine-spirocycloalkanediones by Three-Component Reaction of 5-Aminopyrazole Derivatives, Paraformaldehyde and Cyclic β-Diketones.

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

Regioselective Three-Component Synthesis of Indolylpyrazolo[3,4- b]pyridines Induced by Microwave and under Solvent-Free Conditions

B. Insuasty, J. Quiroga, R. Abonía, 2009 .

Microwave-assisted synthesis of pyrazolo[3,4-d]pyrimidines from 2-amino-4,6-dichloropyrimidine-5-carbaldehyde under solvent-free conditions

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Three hexahydropyridopyrimidine-spiro-cyclohexanetriones: supramolecular structures generated by O—H⋯O, N—H⋯O, C—H⋯O and C—H⋯π hydrogen bonds, and π–π stacking interactions

J. N. Low, C. Glidewell, J. Quiroga, 2004 .

Molecular conformation and supramolecular aggregation in two fused pyrazoles: pi-stacked R(2)(2)(6) dimers in 2,8,8-trimethyl-6,7,8,9-tetrahydropyrazolo[2,3-a]quinazolin-6-one, and sheets of alternating R(2(2)12) and R(6)(6)(48) rings in 3-tert-butyl-4',4'-dimethyl-1-phenyl-4,5,6,7-tetrahydro-1H-pyr

J. N. Low, C. Glidewell, J. Quiroga, 2004, Acta crystallographica. Section C, Crystal structure communications.

Reactions of 6‐aminopyrimidines with 2‐dimethylaminomethylenetetralone. Regiospecific Synthesis Of 5,6‐Dihydrobenzo [h]pyrimido [4,5‐b] quinolines

B. Insuasty, J. Quiroga, R. Abonía, 2001 .

Highly Efficient and Diastereoselective Synthesis of New Pyrazolylpyrrolizine and Pyrazolylpyrrolidine Derivates by a Three-Component Domino Process

B. Insuasty, J. Quiroga, R. Abonía, 2014, Molecules.

An Efficient Synthesis of Pyrazolo[3,4‐b]pyridine‐4‐spiroindolinones by a Three‐Component Reaction of 5‐Aminopyrazoles, Isatin, and Cyclic β‐Diketones.

Alfredo Perez, B. Insuasty, J. Quiroga, 2011 .

An Efficient Synthesis of 7-(Arylmethyl)-3-tert-butyl-1-phenyl-6,7-dihydro-1H,4H-pyrazolo[3,4-d][1,3]oxazines

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

A versatile synthesis of 4,5‐dihydropyrrolo[1,2‐a]quinoxalines

B. Insuasty, J. Quiroga, R. Abonía, 2001 .

Design, facile synthesis, and evaluation of novel spiro- and pyrazolo[1, 5-c]quinazolines as cholinesterase inhibitors: Molecular docking and MM/GBSA studies

Margarita Gutiérrez, Jaime Gálvez, Jans H. Alzate-Morales, 2018, Comput. Biol. Chem..

Facile sonochemical synthesis of novel pyrazolyne derivates at ambient conditions.

J. Quiroga, Jorge Trilleras, D. Pacheco, 2013, Ultrasonics sonochemistry.

4-(4-Fluorophenyl)-3-methyl-1-phenylindeno[1,2-b]pyrazolo[4,3-e]pyridin-5(1H)-one: sheets built from C—H⋯N, C—H⋯O and C—H⋯π(arene) hydrogen bonds

J. N. Low, C. Glidewell, J. Quiroga, 2006 .

Antimicrobial Activity of Quinoline-Based Hydroxyimidazolium Hybrids

J. Guzman, E. Márquez, B. Insuasty, 2019, Antibiotics.

A facile synthesis of stable β-amino-N-/O-hemiacetals through a catalyst-free three-component Mannich-type reaction

B. Insuasty, J. Quiroga, R. Abonía, 2017 .

Regioselective Three-component Synthesis of Tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-ones

B. Insuasty, J. Quiroga, R. Abonía, 2004 .

A regiospecific three-component one-step cyclocondensation to 6-cyano-5,8-dihydropyrido[2,3-d]pyrimidin-4(3H)-ones. Using microwaves under solvent-free conditions

B. Insuasty, J. Quiroga, R. Abonía, 2001 .

Preparation of 6-chloropyrazolo[3,4-b]pyridine-5-carbaldehydes by Vilsmeier–Haack reaction and its use in the synthesis of heterocyclic chalcones and dipyrazolopyridines

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

Synthesis of 5‐cyanopyrazolo[3,4‐b]pyridines in the reaction of 5‐amino‐3‐methyl‐1‐phenylpyrazole with arylidene derivatives of malonodinitrile and ethyl cyanoacetate

B. Insuasty, J. Quiroga, Mario Alvarado, 1999 .

Regioselective Three-Component Synthesis of Novel Indeno[1,2-b]pyrazolo[4,3-e]pyridines-Fused Derivatives of 4-Azafluororenone Alkaloid.

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Methyl (3aRS,3cRS,6cSR,7RS,8RS,8aSR)-2,5-bis(4-chlorophenyl)-7,9-bis(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4,6-tetraoxododecahydro-1H-dipyrrolo[3,4-a:3',4'-f]pyrrolizine-3b-carboxylate dimethylformamide disolvate: a three-dimensional hydrogen-bonded framework.

C. Glidewell, J. Quiroga, J. Cobo, 2012, Acta crystallographica. Section C, Crystal structure communications.

Catalyst Free Three-Component Synthesis of (.+-.)-Pyrazolylpyrrolopyrroles by 1,3-Dipolar Cycloaddition Reaction.

Alfredo Perez, B. Insuasty, J. Quiroga, 2012 .

Synthesis of 6-(2-hydroxybenzoyl)pyrazolo[1,5-a]pyrimidines by reaction of 5-amino-1H-pyrazoles and 3-formylchromone

J. N. Low, B. Insuasty, J. Quiroga, 2002 .

Regioselective synthesis of novel 4-aryl-2-ethylthio-7-methyl pyrazolo[1,5-a]-[1,3,5]-triazines

B. Insuasty, J. Quiroga, R. Abonía, 2006 .

Synthesis of Novel 5‐Amino‐1‐aroylpyrazoles.

B. Insuasty, J. Quiroga, R. Abonía, 2009 .

Structural comparisons of isomeric series of 7-aryl-benzo[h]pyrazolo[3,4-b]quinolines and 11-aryl-benzo[f]pyrazolo[3,4-b]quinolines.

J. N. Low, C. Glidewell, J. Quiroga, 2008, Acta crystallographica. Section B, Structural science.

Microwave Induced Three‐Component Synthesis and Antimycobacterial Activity of Benzopyrazolo[3,4‐b]quinolindiones.

B. Insuasty, J. Quiroga, R. Abonía, 2014 .

Regioselective Synthesis of Novel Substituted Pyrazolo[1,5‐a]pyrimidines under Solvent‐Free Conditions.

B. Insuasty, J. Quiroga, R. Abonía, 2009 .

SYNTHESIS OF 5-CYANO-4,7-DIHYDROPYRAZOLO[3,4-b]PYRIDIN-4-ONES AND 5-CYANOPYRAZOLO[3,4-b|PYRIDIN-4-ONES IN ONE-STEP BY THE REACTION OF 5-AMINO PYRAZOLONE WITH BENZ ALDEHYDE AND BENZOYLACETONITRILE IN ETHANOL AND BY MICROWAVE RADIATION IN DRY MEDIA

B. Insuasty, J. Quiroga, R. Abonía, 2000 .

Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity

B. Insuasty, J. Quiroga, R. Abonía, 2015, Molecules.

Regioselecive Synthesis of Novel Polyfunctionally Substituted Pyrazolo[1,5‐a]pyrimidines under Solvent‐Free Conditions.

B. Insuasty, J. Quiroga, R. Abonía, 2007 .

Solution-Phase and Solid-Phase Synthesis of 1-Pyrazol-3-ylbenzimidazoles

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Synthesis of Fused Heterocycles from Chalcones and Bifunctional Amines

B. Insuasty, J. Quiroga, H. Meier, 1999 .

Reaction of 5‐Aminopyrazoles with β‐Dimethylaminopropiophenones. Synthesis of New Pyrazolo[3,4‐b]pyridines.

B. Insuasty, J. Quiroga, P. Hernández, 1998 .

A Straightforward Synthesis of Pyrimido[4,5-b]quinoline Derivatives Assisted by Microwave Irradiation.

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

Regioselective Three-Component Synthesis of Indolylpyrazolo[3,4-b]pyridines Induced by Microwave and under Solvent-Free Conditions.

B. Insuasty, J. Quiroga, R. Abonía, 2009 .

Synthesis of Pyrimido[4,5‐b]quinolines in the Reaction of 6‐Aminopyrimidines with Dimedone and Benzaldehydes.

B. Insuasty, J. Quiroga, M. Nogueras, 1998 .

3-(4-Methoxyphenyl)-7,7-dimethyl-1,6,7,8-tetrahydropyrazolo[3,4-b]quinolin-5-one: a chain of centrosymmetric rings built from N-H...N and C-H...pi(arene) hydrogen bonds.

J. N. Low, C. Glidewell, J. Quiroga, 2006, Acta crystallographica. Section C, Crystal structure communications.

3,7,7-Trimethyl-4-(β-naphthyl)-4,7,8,9-tetrahydro-2H-pyrazolo[3,4-b]quinolin-5(6H)-one

J. N. Low, D. Cannon, B. Insuasty, 2001 .

4‐(4‐Methoxyphenyl)‐3,7,7‐trimethyl‐4,7,8,9‐tetrahydro‐2H‐pyrazolo[3,4‐b]quinolin‐5(6H)‐one

J. N. Low, D. Cannon, B. Insuasty, 2001 .

Synthesis of New Oxindoles and Determination of Their Antibacterial Properties

B. Insuasty, J. Quiroga, R. Abonía, 2020 .

Synthesis of novel 6,6a,7,8-tetrahydro-5H-naphtho[1,2-e]pyrimido[4,5-b][1,4]diazepines under microwave irradiation as potential anti-tumor agents.

B. Insuasty, J. Quiroga, R. Abonía, 2010, European journal of medicinal chemistry.

Synthesis of 5‐Cyanopyrazolo[3,4‐b]pyridines in the Reaction of 5‐Amino‐3‐methyl‐1‐phenylpyrazole with Arylidene Derivatives of Malonodinitrile and Ethyl Cyanoacetate.

B. Insuasty, J. Quiroga, Mario Alvarado, 2000 .

Synthesis of 6-Cyanopyrido[2,3-d]pyrimidinones in the Reaction of 6-Amino-4-pyrimidinones with Arylidene Derivatives of Malonodinitrile.

B. Insuasty, J. Quiroga, M. Nogueras, 1999 .

Synthesis of Novel Pyrimido[4,5‐b]quinolin‐4‐ones with Potential Antitumor Activity

B. Insuasty, J. Quiroga, R. Abonía, 2013 .

5‐Cyanoacetylpyrimidines as Intermediates for 7‐Aryl‐6‐cyanopyrido[2,3‐d]pyrimidin‐5‐ones.

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

C-and N-cyanoacetylation of 6-aminopyrimidines with cyanoacetic acid and acetic anhydride

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Synthesis and Evaluation of Novel E‐2‐(2‐Thienyl)‐ and Z‐2‐(3‐Thienyl)‐3‐Arylacrylonitriles as Antifungal and Anticancer Agents

Mahabir P. Gupta, M. Derita, B. Insuasty, 2007, Archiv der Pharmazie.

Synthesis of novel 5‐aryl‐6‐cyano‐3H,8H‐pyrido[2,3‐d]pyrimidine‐4,7‐diones in the reaction of 6‐amino‐4‐pyrimidinones with benzaldehyde and ethyl cyanoacetate

B. Insuasty, J. Quiroga, M. Nogueras, 1999 .

Synthesis of new 6-Aroylpyrido[2,3-d]pyrimidines

B. Insuasty, J. Quiroga, M. Nogueras, 1999 .

Synthesis of 6-cyanopyrido[2,3-d]pyrimidinones in the reaction of 6-amino-4-pyrimidinones with arylidene derivatives of malonodinitrile

B. Insuasty, J. Quiroga, M. Nogueras, 1998 .

Solution-Phase and Solid-Phase Synthesis of 1-Pyrazol-3-ylbenzimidazoles.

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Unexpected intramolecular cyclization of some 2'-aminochalcones to indolin-3-ones mediated by Amberlyst®-15

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Efficient catalyst-free four-component synthesis of novel γ-aminoethers mediated by a Mannich type reaction.

B. Insuasty, J. Quiroga, R. Abonía, 2013, ACS combinatorial science.

2-tert-Butyl-5-methyl-7,8-dihydro-6H-cyclopenta[e]pyrazolo[1,5-a]pyrimidine: molecular stacks built from C-H...pi(pyrazole) hydrogen bonds and pi-pi stacking interactions.

C. Glidewell, J. Quiroga, J. Cobo, 2008, Acta crystallographica. Section C, Crystal structure communications.

Four 2-aryl-8,8-dimethyl-6,7,8,9-tetrahydropyrazolo[2,3-a]quinazolin-6-ones: isolated molecules, hydrogen-bonded dimers, and pi-stacked chains of hydrogen-bonded dimers.

J. N. Low, C. Glidewell, J. Quiroga, 2006, Acta crystallographica. Section C, Crystal structure communications.

5-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3-methyl-2-(methylsulfanyl)-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one monohydrate: complex sheets generated by multiple hydrogen bonds.

J. N. Low, C. Glidewell, J. Quiroga, 2006, Acta crystallographica. Section C, Crystal structure communications.

Three‐Component Synthesis of Hexahydropyridopyrimidine—Spirocyclohexanetriones Induced by Microwave.

B. Insuasty, J. Quiroga, R. Abonía, 2006 .

Synthesis of 2-(p-R-benzoylmethylene)-3-(p-R-phenyl)-1H-quinoxalines

E. Ángeles, B. Insuasty, J. Quiroga, 1998 .

SNAr Reactions on 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde

J. Quiroga, Jorge Trilleras, Alfredo Pérez-Gamboa, 2022, Molbank.

A Novel Class of Selective Acetylcholinesterase Inhibitors: Synthesis and Evaluation of (E)-2-(Benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles

Jans H. Alzate-Morales, Julio Caballero, J. Quiroga, 2012, Molecules.

Synthesis and Structural Analysis of 5‐Cyanodihydropyrazolo[3,4‐b]pyridines.

J. N. Low, B. Insuasty, J. Quiroga, 2001 .

Efficient Synthesis of Novel 3‐Aryl‐5‐(4‐chloro‐2‐morpholinothiazol‐5‐yl)‐4,5‐dihydro‐1H‐pyrazoles and Their Antifungal Activity Alone and in Combination with Commercial Antifungal Agents

B. Insuasty, J. Quiroga, R. Abonía, 2014, Archiv der Pharmazie.

Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety

J. Guzman, B. Insuasty, Alberto Insuasty, 2022, International journal of molecular sciences.

11‐Chloro‐5,7‐dihydro‐6H‐benzothiazolo[2,3‐b]benzo[h]quinazoline

J. N. Low, J. Quiroga, M. Nogueras, 2001 .

A hydrogen-bonded dimer in 6-(4-bromophenyl)-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-b]pyridine and a chain of rings built from N-H...N and C-H...pi(pyridine) hydrogen bonds in 3-(4-nitrophenyl)-4-phenyl-1H-pyrazolo[3,4-b]pyridine.

C. Glidewell, M. Hursthouse, J. Quiroga, 2010, Acta crystallographica. Section C, Crystal structure communications.

Synthesis of Pyrazolo[3,4-b]pyridines and Pyrido[2,3-d]pyrimidinones by Hetero-Diels-Alder Reaction of Pyrazolyl- and Pyrimidinilimines under Microwave Irradiation in Dry Media

B. Insuasty, J. Quiroga, R. Abonía, 2000 .

6‐(2‐Hydroxybenzoyl)‐2‐phenylpyrazolo[1,5‐a]pyrimidine

J. N. Low, D. Cannon, B. Insuasty, 2001 .

6‐(2‐Hydroxybenzoyl)‐2‐(4‐nitrophenyl)pyrazolo[1,5‐a]pyrimidine

J. N. Low, D. Cannon, B. Insuasty, 2001 .

Generation of 6,7‐Dihydro‐5H‐1,3,4‐thiadiazolo[3,2‐a]pyridines — Unexpected Products in the Reaction of 5‐Ethylthio‐1,3,4‐thiadiazole‐2‐amine and 3‐(Dimethylamino)propiophenones

B. Insuasty, J. Quiroga, H. Meier, 1998 .

The Formation of Pyrazolo(1,5-a)pyrimidines by the Reaction of 3-(4- Chlorophenyl)pyrazol-5-amine with Chalcones.

B. Insuasty, J. Quiroga, H. Meier, 1995 .

The reaction of aromatic α,β‐unsaturated ketones with 4,5‐diamino‐1,6‐dihydropyrimidin‐6‐ones

B. Insuasty, J. Quiroga, M. Nogueras, 1994 .

Synthesis of pyrazole and pyrimidine Tröger's-base analogues

B. Insuasty, J. Quiroga, R. Abonía, 2002 .

2-Hydroxyphenyl 2-methylpyrazolo[1,5-a]pyrimidin-6-yl ketone.

J. N. Low, B. Insuasty, J. Quiroga, 2000, Acta crystallographica. Section C, Crystal structure communications.

Synthesis, Characterization, and in vitro Anthelmintic Activity Against Nippostrongylus brasiliensis of New 5‐Aryl‐2‐phenyl‐6,7‐dihydropyrazolo[1,5‐a]pyrimidines.

D. Gamenara, B. Insuasty, J. Quiroga, 1999 .

Synthesis of New 1,3,5-Triazine-Based 2-Pyrazolines as Potential Anticancer Agents

B. Insuasty, J. Quiroga, R. Abonía, 2018, Molecules.

Synthesis of 1‐Substituted 3‐Aryl‐5‐aryl(hetaryl)‐2‐pyrazolines and Study of Their Antitumor Activity

B. Insuasty, Alexis Tigreros, J. Quiroga, 2012, Archiv der Pharmazie.

Synthesis of new bis-3,5-diphenylpyrazolines derivatives linked with alkyl chains

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Solvent-Free Synthesis of Fused Pyrazolo[1,5-a]pyrimidines by Reaction of 5-Amino-1H-pyrazoles and β -Triketones

M. Hursthouse, B. Insuasty, J. Quiroga, 2008 .

Pseudo-Multicomponent Reactions of Arynes with N-Aryl Imines.

J. Quiroga, R. Abonía, Jean Rodriguez, 2015, The Journal of organic chemistry.

Synthesis and Structure Elucidation of New Regioisomeric 2‐Alkylamino‐6‐aryl‐8,9‐dihydropyrimido[4,5‐b][1,4]diazepin‐4(7H)‐ones

B. Insuasty, J. Quiroga, R. Abonía, 2014 .

Microwave-assisted synthesis of new regioisomeric 6,7-dihydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepin-5(5aH)-ones

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

A Simple Two-Step Sequence for the Synthesis of Novel 4-Aryl-4,5-dihydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[1,2-a][1]benzazepin-6-ones from 6-Amino-3,4-methylenedioxyacetophenone

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Use of ?-(N,N-dialkylamino)Propiophenones in the Synthesis of Nitrogenated Heterocyclic Compounds

B. Insuasty, J. Quiroga, R. Abonía, 2004 .

Annelation of pyrrolo[1,2-a]pyrimidine and pyrido[1,2-a]pyrimidine systems to a pyrazolopyridine framework by a cascade of two cyclization reactions

B. Insuasty, J. Quiroga, R. Abonía, 2015 .

Synthesis and in Vitro Antitumor Activity of a Novel Series of 2-Pyrazoline Derivatives Bearing the 4-Aryloxy-7-chloroquinoline Fragment

B. Insuasty, J. Quiroga, R. Abonía, 2014, Molecules.

Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking

B. Insuasty, J. Quiroga, R. Abonía, 2021, RSC advances.

Synthesis and DFT Calculations of Novel Vanillin-Chalcones and Their 3-Aryl-5-(4-(2-(dimethylamino)-ethoxy)-3-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbaldehyde Derivatives as Antifungal Agents

B. Insuasty, Alberto Insuasty, J. Quiroga, 2017, Molecules.

Synthesis of novel quinoline-based 4,5-dihydro-1H-pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents.

S. Robledo, I. Velez, B. Insuasty, 2017, European journal of medicinal chemistry.

Novel (E)-1-(pyrrole-2-yl)-3-(aryl)-2-(propen-1-one) derivatives as efficient singlet oxygen quenchers: kinetics and quantum chemical calculations

W. Vallejo, X. Zarate, Stephanie Ortiz, 2015 .

Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents

B. Insuasty, J. Quiroga, R. Abonía, 2018, Molecules.

4-Aminopyrimidine-5-carbaldehydes as intermediates in a Friedländer type synthesis of 7-arylpyrido(2,3-d)pyrimidines

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

5-Amino-1-benzoyl-3-methylpyrazole: complex sheets built from N-H...N, C-H...O and C-H...pi(arene) hydrogen bonds.

C. Glidewell, M. Hursthouse, J. Quiroga, 2010, Acta crystallographica. Section C, Crystal structure communications.

QSAR Studies, Molecular Docking, Molecular Dynamics, Synthesis, and Biological Evaluation of Novel Quinolinone-Based Thiosemicarbazones against Mycobacterium tuberculosis

E. Márquez, B. Insuasty, Alberto Insuasty, 2022, Antibiotics.

An Efficient Two-Step Synthesis of Novel Thiazolo[2,3-b]pyrazolo[3,4-f][1,3,5]triazepines

B. Insuasty, Alexis Tigreros, J. Quiroga, 2009 .

SYNTHESIS INDUCED BY MICROWAVE IRRADIATIO AND IN VITRO ANTIFUNGAL EVALUATION OF NEW DIHYDROPYRAZOLO[3,4-b] [1,4]DIAZEPINES

B. Insuasty, J. Quiroga, R. Abonía, 2004 .

2-Amino-4-(piperidin-1-yl)-11H-pyrimido[4,5-b][1,5]benzodiazepin-6-ium chloride monohydrate and 2-amino-4-[methyl(2-methylphenyl)amino]-11H-pyrimido[4,5-b][1,5]benzodiazepin-6-ium chloride-benzene-1,2-diamine (1/1): complex sheets generated by multiple hydrogen bonds.

C. Glidewell, J. Quiroga, J. Cobo, 2010, Acta crystallographica. Section C, Crystal structure communications.

Hybrid Molecules Containing a 7-Chloro-4-aminoquinoline Nucleus and a Substituted 2-Pyrazoline with Antiproliferative and Antifungal Activity

M. Derita, B. Insuasty, J. Quiroga, 2016, Molecules.

New chalcone-sulfonamide hybrids exhibiting anticancer and antituberculosis activity.

L. Vannucci, J. Guzman, B. Insuasty, 2019, European journal of medicinal chemistry.

Design, synthesis, and molecular docking study of novel quinoline‐based bis‐chalcones as potential antitumor agents

Gabriela L. Borosky, K. Laali, B. Insuasty, 2021, Archiv der Pharmazie.

Synthesis, biological evaluation, and in silico studies of novel chalcone- and pyrazoline-based 1,3,5-triazines as potential anticancer agents

A. Lauria, B. Insuasty, J. Quiroga, 2020, RSC advances.

In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

S. Heeb, M. Cámara, J. Dubern, 2018, Molecules.

Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-R-styryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines‡

E. Ángeles, B. Insuasty, J. Quiroga, 2001, Molecules.

Synthesis of New 1-Benzyl-4,6-diaryl-2,3-dihydropyrazolo[3,4-b][1,4]diazepines

B. Insuasty, J. Quiroga, R. Abonía, 2000 .

Synthesis of substituted 1‐benzyl‐2,4,6‐triphenyl‐2,3‐dihydro‐pyrazolo [3,4‐b] [1,4]diazepines

E. Ángeles, B. Insuasty, J. Quiroga, 1997 .

Bis(5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)-3,4,5-trimethoxyphenylmethane: sheets built from N—H⋯N and N—H⋯O hydrogen bonds

J. N. Low, C. Glidewell, J. Quiroga, 2004 .

6-amino-2-(3,4-dimethoxybenzylamino)-3-methyl-5-nitrosopyrimidin-4(3H)-one: hydrogen-bonded sheets form interdigitated bilayers.

J. N. Low, C. Glidewell, J. Quiroga, 2003, Acta Crystallographica Section C: Crystal Structure Communications.

Regioselective Formylation of Pyrazolo[3,4‐b]pyridine and Pyrazolo[1,5‐a]pyrimidine Systems Using Vilsmeier—Haack Conditions.

B. Insuasty, J. Quiroga, R. Abonía, 2008 .

Synthesis, photophysical properties and theoretical studies of new bis-quinolin curcuminoid BF2-complexes and their decomplexed derivatives.

B. Insuasty, J. Quiroga, R. Abonía, 2020, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

3-tert-Butyl-7,7-dimethyl-1-phenyl-5,6,7,8-tetrahydroimidazo[3,4-b]quinolin-5-one and 2,8,8-trimethyl-5-phenyl-6,7,8,9-tetrahydroimidazo[2,3-a]quinolin-6-one: chains generated by C-H...N hydrogen bonds.

J. N. Low, C. Glidewell, J. Quiroga, 2004, Acta crystallographica. Section C, Crystal structure communications.

4-Amino-5-(2-hydroxy-4,4-dimethyl-6-oxocyclohexenylmethyl)-1-methyl-2-(methylsulfanyl)pyrimidin-6(1H)-one: hydrogen-bonded chains are pi-stacked in pairs.

J. N. Low, C. Glidewell, J. Quiroga, 2004, Acta crystallographica. Section C, Crystal structure communications.

5-Amino-3-tert-butyl-1-(4-nitrophenyl)-1H-pyrazole forms hydrogen-bonded sheets of alternating R2(2)(20) and R6(6)(32) rings.

J. N. Low, C. Glidewell, J. Quiroga, 2004, Acta crystallographica. Section C, Crystal structure communications.

Weak and strong hydrogen-bonding patterns in the structure of 2,4-bis(2-hydroxybenzoyl)-2,3-dihydro-1H-pyrido[2,1-b][1,3]benzothiazole

J. N. Low, B. Insuasty, J. Quiroga, 2000 .

A Simple One-Pot Synthesis of New Imidazol-2-yl-1H-quinolin-2-ones from the Direct Reaction of 2-Chloroquinolin-3-carbaldehyde with Aromatic o-Diamines

B. Insuasty, J. Quiroga, R. Abonía, 2010 .

3-[5-(4-Bromophenyl)-1H-pyrazol-3-ylamino]-5,5-dimethylcyclohex-2-en-1-one-(Z)-3-(4-bromophenyl)-3-chloroacrylonitrile (2/1): a stoichiometric cocrystal of a reaction product with one of its early precursors.

J. N. Low, C. Glidewell, J. Quiroga, 2006, Acta crystallographica. Section C, Crystal structure communications.

A monoclinic polymorph of 3,7,7-trimethyl-1-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-5-one.

J. N. Low, C. Glidewell, J. Quiroga, 2005, Acta crystallographica. Section C, Crystal structure communications.

Two isomeric pairs of dihydrobenzopyrazoloquinazolines: centrosymmetric dimers, chains and sheets built from C—H⋯N and C—H⋯π(arene) hydrogen bonds and π–π stacking interactions

J. N. Low, C. Glidewell, J. Quiroga, 2005 .

11-(4-Bromophenyl)-10-methyl-8-phenyl-6,8-dihydro-5H-benzo[f]pyrazolo[3,4-b]quinoline

J. N. Low, C. Glidewell, J. Quiroga, 2005 .

2,2'-Methylenebis(3-hydroxy-5,5-dimethylcyclohex-2-en-1-one).

J. N. Low, C. Glidewell, J. Quiroga, 2003, Acta Crystallographica Section C: Crystal Structure Communications.

3,7,7-Trimethyl-1-phenyl-1,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one

J. N. Low, J. Quiroga, J. Cobo, 2003 .

Synthesis of 3-aryl-1,2,4-benzotriazines via intramolecular cyclization of solid-supported o-hydrazidoanilines

B. Insuasty, J. Quiroga, R. Abonía, 2012, Molecular Diversity.

Hydrogen-bonded assembly in six closely related pyrazolo[3,4-b]pyridine derivatives; a simple chain, three types of chains of rings and a complex sheet structure.

C. Glidewell, J. Quiroga, J. Cobo, 2012, Acta crystallographica. Section C, Crystal structure communications.

Synthesis of pyrimido[4,5-b]quinolindiones and formylation: ultrasonically assisted reactions

J. Quiroga, Jorge Trilleras, Paola Acosta‐Guzmán, 2024, Royal Society open science.

1‐Alkyl‐ and Azeto[1,2‐a][1,5]benzodiazepine Derivatives in the Reaction of o‐Phenylenediamine with 3‐(Dimethylamino)propiophenones

B. Insuasty, J. Quiroga, R. Abonía, 2000 .

Synthesis of Novel Triazine-Based Chalcones and 8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepines as Potential Leads in the Search of Anticancer, Antibacterial and Antifungal Agents

B. Insuasty, J. Quiroga, R. Abonía, 2024, International journal of molecular sciences.

7-Amino-2-tert-butyl-5-methylpyrazolo[1,5-a]pyrimidine: a three-dimensional framework structure built from two N-H...N hydrogen bonds.

J. N. Low, C. Glidewell, J. Quiroga, 2007, Acta crystallographica. Section C, Crystal structure communications.

A hydrogen-bonded chain of rings in 7-amino-5-tert-butyl-2-methylpyrazolo[1,5-a]pyrimidine, and a hydrogen-bonded framework structure in 3,7-diamino-2,5-dimethylpyrazolo[1,5-a]pyrimidine monohydrate.

J. N. Low, C. Glidewell, J. Quiroga, 2006, Acta crystallographica. Section C, Crystal structure communications.

7-Amino-2,5-dimethylpyrazolo[1,5-a]pyrimidine hemihydrate redetermined at 120 K: a three-dimensional hydrogen-bonded framework.

J. N. Low, C. Glidewell, J. Quiroga, 2006, Acta crystallographica. Section C, Crystal structure communications.

2-Cyano-N-(4,6-dimethoxypyrimidin-2-yl)acetamide: complex sheets built from N-H...O and C-H...O hydrogen bonds.

C. Glidewell, J. Quiroga, J. Cobo, 2010, Acta crystallographica. Section C, Crystal structure communications.