A. Bouhss

发表

Invariant amino acids in the Mur peptide synthetases of bacterial peptidoglycan synthesis and their modification by site-directed mutagenesis in the UDP-MurNAc:L-alanine ligase from Escherichia coli.

D. Mengin-Lecreulx, D. Blanot, J. van Heijenoort, 1997, Biochemistry.

Formation of adenosine 5′‐tetraphosphate from the acyl phosphate intermediate: a difference between the MurC and MurD synthetases of Escherichia coli

D. Blanot, J. van Heijenoort, A. Bouhss, 1999, FEBS letters.

Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments.

J. Heijenoort, O. Dideberg, D. Mengin-Lecreulx, 2001, European journal of biochemistry.

MurC and MurD synthetases of peptidoglycan biosynthesis: borohydride trapping of acyl-phosphate intermediates.

D. Blanot, J. van Heijenoort, A. Bouhss, 2002, Methods in enzymology.

The MurE Synthetase from Thermotoga maritima Is Endowed with an Unusual d-Lysine Adding Activity*

D. Mengin-Lecreulx, D. Blanot, A. Boniface, 2006, Journal of Biological Chemistry.

Role of the ortholog and paralog amino acid invariants in the active site of the UDP-MurNAc-L-alanine:D-glutamate ligase (MurD).

O. Dideberg, D. Mengin-Lecreulx, D. Blanot, 1999, Biochemistry.

5'-Methylene-triazole-substituted-aminoribosyl uridines as MraY inhibitors: synthesis, biological evaluation and molecular modeling.

B. Joris, D. Mengin-Lecreulx, N. Pietrancosta, 2015, Organic & biomolecular chemistry.

Catalytic mechanism of MraY and WecA, two paralogues of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily.

D. Mengin-Lecreulx, D. Blanot, A. Bouhss, 2016, Biochimie.

Efficient synthesis of a bacterial translocase MraY inhibitor

A. Bouhss, C. Gravier-Pelletier, A. Clouet, 2008 .

Active site mapping of MraY, a member of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily, catalyzing the first membrane step of peptidoglycan biosynthesis.

D. Mengin-Lecreulx, Xavier Henry, D. Blanot, 2008, Biochemistry.

Bacterial transferase MraY inhibitors: synthesis and biological evaluation.

Delphine Lecerclé, A. Bouhss, C. Gravier-Pelletier, 2010, Bioorganic & medicinal chemistry.

Synthesis and Biological Evaluation of Muraymycin Analogues Active against Anti-Drug-Resistant Bacteria.

A. Matsuda, A. Bouhss, S. Ichikawa, 2010, ACS medicinal chemistry letters.

Synthesis and biological evaluation of a diazepanone-based library of liposidomycins analogs as MraY inhibitors.

Janez Mravljak, A. Bouhss, C. Gravier-Pelletier, 2011, European journal of medicinal chemistry.

Toward analogues of MraY natural inhibitors: synthesis of 5'-triazole-substituted-aminoribosyl uridines through a Cu-catalyzed azide-alkyne cycloaddition.

A. Bouhss, Mickaël J. Fer, Sandrine Calvet-Vitale, 2013, The Journal of organic chemistry.

Importance of the Conserved Residues in the Peptidoglycan Glycosyltransferase Module of the Class A Penicillin-binding Protein 1b of Escherichia coli*

E. Sauvage, E. Breukink, M. Terrak, 2008, Journal of Biological Chemistry.

YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

G. Lambert, D. Pastré, P. Curmi, 2019, Nucleic acids research.

Deciphering the metabolism of undecaprenyl-phosphate: the bacterial cell-wall unit carrier at the membrane frontier.

R. Auger, D. Mengin-Lecreulx, H. Barreteau, 2014, Microbial drug resistance.

Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities

C. Dowson, D. Roper, A. Bouhss, 2019, Molecules.

Squalamine and Aminosterol Mimics Inhibit the Peptidoglycan Glycosyltransferase Activity of PBP1b

E. Breukink, A. Boes, F. Kerff, 2020, Antibiotics.

Human- and Plant-Pathogenic Pseudomonas Species Produce Bacteriocins Exhibiting Colicin M-Like Hydrolase Activity towards Peptidoglycan Precursors

J. Mainardi, M. Fourgeaud, D. Mengin-Lecreulx, 2009, Journal of bacteriology.

Colicin M Exerts Its Bacteriolytic Effect via Enzymatic Degradation of Undecaprenyl Phosphate-linked Peptidoglycan Precursors*

D. Mengin-Lecreulx, D. Blanot, H. Barreteau, 2006, Journal of Biological Chemistry.

Synthesis and biological evaluation of chemical tools for the study of Dolichol Linked Oligosaccharide Diphosphatase (DLODP).

A. Bouhss, C. Gravier-Pelletier, I. Chantret, 2017, European journal of medicinal chemistry.

X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia coli Colicin M Immunity Protein (cid:1) †

M. Graille, H. Tilbeurgh, D. Mengin-Lecreulx, 2010 .

The Combined activities of FtsW and MurJ are required for lipid II translocation during cell division in Escherichia coli

T. den Blaauwen, A. Bouhss, Xiaolong Liu, 2017, bioRxiv.

Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane

T. Vernet, B. de Kruijff, E. Breukink, 2011, The EMBO journal.

Pectocin M1 (PcaM1) Inhibits Escherichia coli Cell Growth and Peptidoglycan Biosynthesis through Periplasmic Expression

Sean Giacomucci, D. Mengin-Lecreulx, D. Patin, 2016, Antibiotics.

Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa *

M. Graille, H. van Tilbeurgh, J. Mainardi, 2012, The Journal of Biological Chemistry.

Purification and Characterization of the Bacterial UDP-GlcNAc:Undecaprenyl-Phosphate GlcNAc-1-Phosphate Transferase WecA

D. Mengin-Lecreulx, A. Bouhss, B. Al-Dabbagh, 2008, Journal of bacteriology.

Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemX(Wv) aminoacyl transferase.

M. Lecerf, D. Mengin-Lecreulx, M. Arthur, 2013, Chemistry.

Synthesis of the l-Alanyl-l-alanine Cross-bridge of Enterococcus faecalis Peptidoglycan*

D. Mengin-Lecreulx, M. Arthur, J. van Heijenoort, 2002, The Journal of Biological Chemistry.

Fluorescence Detection-Based Functional Assay for High-Throughput Screening for MraY

D. Mengin-Lecreulx, P. Ferrari, J. Biton, 2004, Antimicrobial Agents and Chemotherapy.

Specific interactions of clausin, a new lantibiotic, with lipid precursors of the bacterial cell wall.

M. Aumont-Nicaise, M. Desmadril, D. Mengin-Lecreulx, 2009, Biophysical journal.

Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers.

D. Mengin-Lecreulx, D. Blanot, A. Bouhss, 2009, Analytical biochemistry.

Synthesis and biological evaluation of potential new inhibitors of the bacterial transferase MraY with a β-ketophosphonate structure.

A. Bouhss, R. Frlan, C. Gravier-Pelletier, 2011, Organic & biomolecular chemistry.

Membrane Topology and Biochemical Characterization of the Escherichia coli BacA Undecaprenyl-Pyrophosphate Phosphatase

R. Auger, D. Mengin-Lecreulx, F. Kerff, 2015, PloS one.

Deciphering the Catalytic Domain of Colicin M, a Peptidoglycan Lipid II-degrading Enzyme*

R. Lloubès, D. Duché, D. Mengin-Lecreulx, 2010, The Journal of Biological Chemistry.

Mechanistic analysis of muraymycin analogues: a guide to the design of MraY inhibitors.

A. Matsuda, D. Mengin-Lecreulx, A. Bouhss, 2011, Journal of medicinal chemistry.

Structure-Based Site-Directed Mutagenesis of the UDP-MurNAc-Pentapeptide-Binding Cavity of the FemX Alanyl Transferase from Weissella viridescens

M. Arthur, W. Sougakoff, C. Mayer, 2005, Journal of bacteriology.

Structural characterization by nuclear magnetic resonance spectroscopy of a genetically engineered high-affinity calmodulin-binding peptide derived from Bordetella pertussis adenylate cyclase.

A. Gilles, O. Bârzu, C. Craescu, 1995, Archives of biochemistry and biophysics.

The biosynthesis of peptidoglycan lipid-linked intermediates.

T. Bugg, D. Mengin-Lecreulx, A. Bouhss, 2008, FEMS microbiology reviews.

Purification and Characterization of the Bacterial MraY Translocase Catalyzing the First Membrane Step of Peptidoglycan Biosynthesis*

D. Mengin-Lecreulx, D. Blanot, A. Bouhss, 2004, Journal of Biological Chemistry.

Identification of the UDP-MurNAc-Pentapeptide:l-Alanine Ligase for Synthesis of Branched Peptidoglycan Precursors in Enterococcus faecalis

J. Mainardi, D. Mengin-Lecreulx, M. Arthur, 2001, Journal of bacteriology.

Decoding the logic of the tRNA regiospecificity of nonribosomal FemX(Wv) aminoacyl transferase.

M. Lecerf, M. Arthur, A. Bouhss, 2010, Angewandte Chemie.

Identification of Multiple Genes Encoding Membrane Proteins with Undecaprenyl Pyrophosphate Phosphatase (UppP) Activity in Escherichia coli*

A. Derbise, D. Mengin-Lecreulx, A. Bouhss, 2005, Journal of Biological Chemistry.

The bacA Gene of Escherichia coli Encodes an Undecaprenyl Pyrophosphate Phosphatase Activity*

D. Mengin-Lecreulx, D. Blanot, A. Bouhss, 2004, Journal of Biological Chemistry.

Conformational transitions within the calmodulin-binding site of Bordetella pertussis adenylate cyclase studied by time-resolved fluorescence of Trp242 and circular dichroism.

A. Danchin, A. Gilles, O. Bârzu, 1996, European journal of biochemistry.

Nanoscale Analysis Reveals the Maturation of Neurodegeneration-Associated Protein Aggregates: Grown in mRNA Granules then Released by Stress Granule Proteins.

D. Pastré, L. Hamon, D. Kretov, 2017, ACS nano.

The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation

Krystel El Hage, D. Pastré, Marie-Jeanne Clément, 2021, eLife.

Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors

Krystel El Hage, D. Pastré, Marie-Jeanne Clément, 2022, bioRxiv.

Contribution of the Pmra Promoter to Expression of Genes in the Escherichia coli mra Cluster of Cell Envelope Biosynthesis and Cell Division Genes

D. Mengin-Lecreulx, H. Hara, J. van Heijenoort, 1998, Journal of bacteriology.

YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells

Krystel El Hage, D. Pastré, A. Maucuer, 2021, Nucleic acids research.

Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

G. Lambert, Krystel El Hage, D. Pastré, 2021, Communications biology.

FtsW activity and lipid II synthesis are required for recruitment of MurJ to midcell during cell division in Escherichia coli

T. den Blaauwen, A. Bouhss, Xiaolong Liu, 2018, Molecular microbiology.

FtsW activity and lipid II synthesis are required for recruitment of MurJ to midcell during cell division in E. coli

A. Bouhss, Xiaolong Liu, N. Y. Meiresonne, 2018 .

Structural flexibility of the calmodulin-binding locus in Bordetella pertussis adenylate cyclase. Reconstitution of catalytically active species from fragments or inactive forms of the enzyme.

A. Danchin, E. Krin, A. Gilles, 1993, European journal of biochemistry.

Colicin M, a peptidoglycan lipid-II-degrading enzyme: potential use for antibacterial means?

D. Duché, D. Mengin-Lecreulx, M. Arthur, 2012, Biochemical Society transactions.

Characterization of colicin M and its orthologs targeting bacterial cell wall peptidoglycan biosynthesis.

Herman van Tilbeurgh, Hélène Barreteau, H. van Tilbeurgh, 2012, Microbial drug resistance.

Colicin M hydrolyses branched lipids II from Gram-positive bacteria.

S. Magnet, D. Mengin-Lecreulx, M. Arthur, 2012, Biochimie.

Calmodulin Binding of a Peptide Derived from the Regulatory Domain of Bordetella pertussis Adenylate Cyclase (*)

A. Popescu, C. Craescu, J. Mispelter, 1995, The Journal of Biological Chemistry.

The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli

D. Mengin-Lecreulx, T. den Blaauwen, A. Bouhss, 2007, Molecular microbiology.

Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria.

A. Matsuda, A. Bouhss, S. Ichikawa, 2010, Journal of medicinal chemistry.

Bacterial Transferase MraY, a Source of Inspiration towards New Antibiotics.

N. Pietrancosta, A. Bouhss, L. L. Corre, 2019, Current medicinal chemistry.

Topological analysis of the MraY protein catalysing the first membrane step of peptidoglycan synthesis

D. Mengin-Lecreulx, J. van Heijenoort, D. Le Beller, 1999, Molecular microbiology.

PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA.

D. Pastré, L. Hamon, V. Joshi, 2019, Cell reports.

X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia coli Colicin M Immunity Protein

M. Graille, H. van Tilbeurgh, D. Mengin-Lecreulx, 2010, Journal of bacteriology.

Characterization and chromosomal organization of the murD-murC-ftsQ region of Corynebacterium glutamicum ATCC 13869.

D. Mengin-Lecreulx, J. Gil, A. Bouhss, 2004, Research in microbiology.

Cooperative phenomena in binding and activation of Bordetella pertussis adenylate cyclase by calmodulin.

A. Danchin, E. Krin, A. Gilles, 1993, The Journal of biological chemistry.

CbrA Mediates Colicin M Resistance in Escherichia coli through Modification of Undecaprenyl-Phosphate-Linked Peptidoglycan Precursors

D. Mengin-Lecreulx, D. Patin, D. Blanot, 2020, Journal of Bacteriology.

Microtubules as platforms for probing liquid–liquid phase separation in cells – application to RNA-binding proteins

D. Pastré, P. Curmi, A. Maucuer, 2018, Journal of Cell Science.

Structural and Functional Organization of the Catalytic Domain of a Bacterial Toxin: bordetella Pertussis Adenylate Cyclase

A. Danchin, E. Krin, A. Gilles, 1992 .

Synthesis of Lipid-Carbohydrate-Peptidyl-RNA Conjugates to Explore the Limits Imposed by the Substrate Specificity of Cell Wall Enzymes on the Acquisition of Drug Resistance.

T. Brown, D. Mengin-Lecreulx, M. Arthur, 2018, Chemistry.

The role of histidine 63 in the catalytic mechanism of Bordetella pertussis adenylate cyclase.

A. Danchin, E. Krin, A. Gilles, 1992, The Journal of biological chemistry.

Aminoacyl-tRNA recognition by the FemXWv transferase for bacterial cell wall synthesis

M. Lecerf, M. Arthur, A. Bouhss, 2009, Nucleic acids research.

A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling

B. Joris, A. Bouhss, A. Amoroso, 2022, Molecules.

Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors.

B. Joris, R. Auger, A. Bouhss, 2021, Organic & biomolecular chemistry.

Preparative Scale Cell-free Production and Quality Optimization of MraY Homologues in Different Expression Modes*

Volker Dötsch, Umesh Ghoshdastider, Frank Bernhard, 2011, The Journal of Biological Chemistry.