Tianyuan Zhang

发表

Structure-activity relationships of novel potent MurF inhibitors.

David D. Anderson, P. Hajduk, R. Clark, 2004, Bioorganic & medicinal chemistry letters.

Structure‐based Optimization of MurF Inhibitors

David D. Anderson, P. Hajduk, K. Longenecker, 2006, Chemical biology & drug design.

Phenoxy thiazole derivatives as potent and selective acetyl-CoA carboxylase 2 inhibitors: Modulation of isozyme selectivity by incorporation of phenyl ring substituents.

H. Sham, R. Clark, Y. Gu, 2007, Bioorganic & medicinal chemistry letters.

Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity.

H. Sham, R. Clark, Gang Liu, 2006, Bioorganic & medicinal chemistry letters.

Construction of a CF3-Containing Benzofurofuranone Skeleton from Coumarins via Reductive Coupling and Acid-Mediated Ring Contraction.

Shuhei Fukaya, Tianyuan Zhang, Y. Shimizu, 2019, The Journal of organic chemistry.

N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.

J. Waring, H. Sham, E. Blomme, 2007, Journal of medicinal chemistry.

Selective Introduction of Trifluoroacetyl Group to β- and δ-Position of Aromatic Conjugated Esters: Facile Synthesis of Fluorine-containing Keto Esters

K. Shimizu, Tianyuan Zhang, Y. Shimizu, 2019, Asian Journal of Organic Chemistry.

Synthesis of 4-(Trifluoromethyl)cyclopentenones and 2-(Trifluoromethyl)furans by Reductive Trifluoroacetylation of Ynones.

Tianyuan Zhang, H. Maekawa, 2017, Organic letters.

Regioselective Silylations of Propargyl and Allyl Pivalates through Ca-Promoted Reductive C(sp3)-O Bond Cleavage.

Tianyuan Zhang, Suhua Zheng, H. Maekawa, 2021, Organic letters.

Diastereoselective Trapping of Transient Carboxylic Oxonium Ylides with α,β‐Unsaturated 2‐Acyl Imidazoles

Tianyuan Zhang, Wenhao Hu, Dan Zhang, 2020 .

Structural Modification of Saccharin Containing 2‐Aminothiazole As Potential Fungicidal Agents

Tianyuan Zhang, Yong‐Xian Cheng, Danling Huang, 2022, ChemistrySelect.

3CLpro inhibitors: DEL-based molecular generation

Lanmei Zhang, Tianyuan Zhang, Jiaqi Wu, 2022, Frontiers in Pharmacology.

Discovery of TIGIT inhibitors based on DEL and machine learning

Tianyuan Zhang, Zhenwei Li, Zhixuan Zeng, 2022, Frontiers in Chemistry.

Design, synthesis, fungicidal activities and structure-activity relationship studies of (-)-borneol derivatives containing 2-aryl-thiazole scaffold.

Tianyuan Zhang, Yong‐Xian Cheng, Danling Huang, 2021, Bioorganic & medicinal chemistry letters.

Design, Synthesis and Fungicidal Activity of Novel 2‐aryl‐thiazole Derivatives Containing Saccharin Motif

Tianyuan Zhang, Yong‐Xian Cheng, Yunjun Zhou, 2020 .

Facile and highly selective silylation of vinylpyridines at the β-olefinic carbon by magnesium-promoted reduction

Tianyuan Zhang, Yutaro Nishiyama, H. Maekawa, 2016 .

Novel inhibitors of bacterial protein synthesis: structure-activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants.

N. Soni, R. Clark, Y. Gu, 2004, Bioorganic & medicinal chemistry letters.

Design and synthesis of potential fungicidal compounds derived from natural products, (-)-menthol and (-)-borneol

Tianyuan Zhang, Yong‐Xian Cheng, Danling Huang, 2022, Medicinal Chemistry Research.

A Rh(II)-catalyzed highly stereoselective [3 + 2] annulation of vinyl diazoacetates with indole-2-carbaldehyde for the synthesis of indolyl dihydrofurans

Tianyuan Zhang, Xin-ru Yin, Wenhao Hu, 2022, Molecular Diversity.

Magnesium-promoted reductive acylation of aromatic conjugated ynones accompanying with transposition of the triple bond

A. Takano, Tianyuan Zhang, Yutaro Nishiyama, 2015 .

Reductive 3-Silylation of Benzofuran Derivatives via Coupling Reaction with Chlorotrialkylsilane.

Tianyuan Zhang, Suhua Zheng, H. Maekawa, 2020, The Journal of organic chemistry.

A Simple Protocol from Benzalacetones to 1,1,1-Trifluoro-2,5-diketones and 2-(Trifluoromethyl)furans by Reductive Trifluoroacetylation

Tianyuan Zhang, H. Maekawa, Chunchao Xie, 2020 .

Facile synthesis of silyl allenol ethers and β-silyl enones through reductive silylation of benzoylacetylenes

Tianyuan Zhang, H. Maekawa, Tomoya Hasegawa, 2022, Tetrahedron.

From Bacterial Genomes to Novel Antibacterial Agents: Discovery, Characterization, and Antibacterial Activity of Compounds that Bind to HI0065 (YjeE) from Haemophilus influenzae

P. Hajduk, K. Comess, Liping Yu, 2007, Chemical biology & drug design.

Discovery of Novel Celastrol-Imidazole Derivatives with Anticancer Activity In Vitro and In Vivo.

Na Li, Cheng Chen, Zhichao Lei, 2022, Journal of medicinal chemistry.

α-Linolenic acid alleviates aluminum toxicity in RAW264.7 cells by antioxidative and anti-inflammatory effects

Ling Han, X. Xia, Xia Xiang, 2023, Arabian Journal of Chemistry.

Magnesium-Promoted Reductive Carboxylation of Aryl Vinyl Ketones: Synthesis of γ-Keto Carboxylic Acids.

Tianyuan Zhang, Suhua Zheng, H. Maekawa, 2022, The Journal of organic chemistry.

Regio- and diastereoselective construction of conjugate oxindole derivatives enabled by delayed acyl transfer of pyridinium ylides

Tianyuan Zhang, Wenhao Hu, Kemiao Hong, 2023, Organic Chemistry Frontiers.

Identification of a monoacid-based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B.

P. Hajduk, C. Abad-Zapatero, Xiaofen Li, 2003, Bioorganic & Medicinal Chemistry Letters.

Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors.

Gang Liu, C. Abad-Zapatero, Xiaofen Li, 2003, Bioorganic & medicinal chemistry letters.

A sustainable synthesis of 3,3-disubstituted oxindoles via CuBr-catalysed capture of carboxylic oxonium ylides with isatylidene malononitrile

Tianyuan Zhang, Wenhao Hu, Taoda Shi, 2023, Green Synthesis and Catalysis.

Phenoxy Thiazole Derivatives as Potent and Selective Acetyl‐CoA Carboxylase 2 Inhibitors: Modulation of Isozyme Selectivity by Incorporation of Phenyl Ring Substituents.

H. Sham, R. Clark, Y. Gu, 2007 .

Synthesis and Structure−Activity Relationships of N-{3-[2-(4-Alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy Derivatives as Selective Acetyl-CoA Carboxylase 2 Inhibitors

H. Sham, Gang Liu, Y. Gu, 2006 .