Laura Friggeri

发表

Activity of caffeic acid derivatives against Candida albicans biofilm.

F. D. D'Auria, A. Palamara, R. Di Santo, 2014, Bioorganic & medicinal chemistry letters.

Discovery of in vitro antitubercular agents through in silico ligand-based approaches.

C. Zamperini, M. Botta, M. Mori, 2016, European journal of medicinal chemistry.

S0031182018000562jrv 1820..1836

M. Waterman, G. Lepesheva, Laura Friggeri, 2018 .

Pharmacophore Assessment Through 3-D QSAR: Evaluation of the Predictive Ability on New Derivatives by the Application on a Series of Antitubercular Agents

R. Costi, R. D. Santo, R. Ragno, 2013, J. Chem. Inf. Model..

CYP51 as drug targets for fungi and protozoan parasites: past, present and future

M. Waterman, G. Lepesheva, Laura Friggeri, 2018, Parasitology.

Sterol 14α-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis.

Anna L. Blobaum, W. D. Nes, M. Botta, 2018, Journal of medicinal chemistry.

Sterol 14α-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae.

Anna L. Blobaum, W. D. Nes, C. Lindsley, 2018, Journal of medicinal chemistry.

Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine

J. Meiler, Z. Freyberg, R. Logan, 2022, iScience.

Efficient Synthesis of 3,5‐Dicarbamoyl‐1,4‐dihydropyridines from Pyridinium Salts: Key Molecules in Understanding NAD(P)+/NAD(P)H Pathways

Alessandro Padova, P. Mellini, Laura Friggeri, 2015 .

Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis

J. York, Z. Wawrzak, F. Guengerich, 2017, The Journal of Biological Chemistry.

Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein.

M. Botta, M. Zazzi, Y. Mély, 2018, ACS medicinal chemistry letters.

Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design1

M. Waterman, Z. Wawrzak, F. Guengerich, 2016, Journal of Lipid Research.

Efficient Electrochemical N-Alkylation of N-Boc-Protected 4-Aminopyridines: Towards New Biologically Active Compounds

F. D. D'Auria, R. Di Santo, L. Maes, 2014, ISRN organic chemistry.

New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi.

C. Zamperini, R. Di Santo, R. Costi, 2013, ACS medicinal chemistry letters.

Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma cruzi Sterol 14α-Demethylase: Two Regions of the Enzyme Molecule Potentiate Its Inhibition

M. Waterman, Z. Wawrzak, F. Villalta, 2014, Journal of medicinal chemistry.

Validation of human sterol 14α-demethylase (CYP51) druggability: structure-guided design, synthesis and evaluation of stoichiometric, functionally irreversible inhibitors.

Z. Wawrzak, F. Guengerich, G. Lepesheva, 2019, Journal of medicinal chemistry.

Design, synthesis and evaluation of 3,4-dihydroxybenzoic acid derivatives as antioxidants, bio-metal chelating agents and acetylcholinesterase inhibitors

R. Di Santo, R. Costi, D. De Vita, 2015, Journal of enzyme inhibition and medicinal chemistry.