K. Maresca

发表

A new strategy for the preparation of peptide-targeted radiopharmaceuticals based on an fmoc-lysine-derived single amino acid chelate (SAAC). automated solid-phase synthesis, NMR characterization, and in vitro screening of fMLF(SAAC)G and fMLF[(SAAC-Re(CO)3)+]G.

J. Zubieta, J. Valliant, N. McFarlane, 2004, Bioconjugate chemistry.

Preclinical evaluation of an 131I-labeled benzamide for targeted radiotherapy of metastatic melanoma.

M. Pomper, K. Gage, L. Dinkelborg, 2010, Cancer research.

A series of halogenated heterodimeric inhibitors of prostate specific membrane antigen (PSMA) as radiolabeled probes for targeting prostate cancer.

A. Kozikowski, W. Eckelman, J. Babich, 2009, Journal of medicinal chemistry.

Synthesis and Evaluation of a Series of 99mTc(CO)3+ Lisinopril Complexes for In Vivo Imaging of Angiotensin-Converting Enzyme Expression

V. Dilsizian, W. Eckelman, J. Babich, 2008, Journal of Nuclear Medicine.

Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.

O. Ilkayeva, C. Lang, C. Lynch, 2012, Schizophrenia bulletin.

Synthesis and characterisation of cobalt and nickel compounds with phosphinothiol ligands. Crystal and molecular structures of [Co{ {2- (Ph2P)-6- (Me3Si)C6H3S)} }3], [Ni{ {2- (Ph2P)-6- (Me3Si)C6H3S)} }2] and [Co{ {2- (Ph2PO)-6- (Me3Si)C6H3S} }2]

J. Zubieta, J. Romero, J. García-Vázquez, 1998 .

99mTc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen for Molecular Imaging of Prostate Cancer

W. Eckelman, J. Marquis, J. Babich, 2013, The Journal of Nuclear Medicine.

Synthesis and SAR of ⁹⁹mTc/Re-labeled small molecule prostate specific membrane antigen inhibitors with novel polar chelates.

W. Eckelman, J. Babich, S. Hillier, 2013, Bioorganic & medicinal chemistry letters.

99m Tc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen for Molecular Imaging of Prostate Cancer

W. Eckelman, J. Marquis, J. Babich, 2013 .

99mTc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen for Molecular Imaging of Prostate Cancer

W. Eckelman, J. Marquis, J. Babich, 2013, The Journal of Nuclear Medicine.

Synthesis and SAR of novel Re/99mTc-labeled benzenesulfonamide carbonic anhydrase IX inhibitors for molecular imaging of tumor hypoxia.

W. Eckelman, J. Babich, S. Hillier, 2013, Journal of medicinal chemistry.

Small molecule inhibitors of PSMA incorporating technetium-99m for imaging prostate cancer: Effects of chelate design on pharmacokinetics

W. Eckelman, J. Marquis, J. Babich, 2012 .

Comparison of high-specific-activity ultratrace 123/131I-MIBG and carrier-added 123/131I-MIBG on efficacy, pharmacokinetics, and tissue distribution.

J. Babich, S. Hillier, K. Maresca, 2010, Cancer biotherapy & radiopharmaceuticals.

Syntheses and structural characterization of rhenium-bis-hydrazinopyrimidine core complexes with thiolate and Schiff base coligands.

J. Zubieta, J. Babich, K. Maresca, 2000, Inorganica chimica acta.

Synthesis and crystal and molecular structure of a tetranuclear cluster based on the rhenium(III)-bisorganohydrazino core: [Re(HNNC(4)H(3)N(2))(NNC(4)H(3)N(2))(OCH(3))(2)](4).

J. Zubieta, J. Babich, K. Maresca, 2000, Inorganica chimica acta.

Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis

C. Lang, Pengxiang She, C. Lynch, 2010, Molecular Psychiatry.

Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib

Steven H. Liang, G. El Fakhri, U. Mahmood, 2017, Nature Communications.

Brain Penetration of the ROS1/ALK Inhibitor Lorlatinib Confirmed by PET

Steven H. Liang, M. Normandin, N. Vasdev, 2017, Molecular imaging.

New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for new chelate design.

J. Zubieta, J. Valliant, S. Banerjee, 2005, Nuclear medicine and biology.

RuIII Complexes of Edta and Dtpa Polyaminocarboxylate Analogues and Their Use as Nitric Oxide Scavengers

J. Zubieta, Michael T. Wilson, T. Storr, 2005 .

[131I]MIP-1466, a small molecule prostate-specific membrane antigen (PSMA) inhibitor for targeted radiotherapy of prostate cancer (PCa)

W. Eckelman, J. Marquis, J. Babich, 2012 .

on Efficacy, Pharmacokinetics, and Tissue Distribution

J. Babich, S. Hillier, K. Maresca, 2018 .

SYNTHESIS AND CHARACTERIZATION OF A BINUCLEAR RHENIUM NITROPYRAZOLE COMPLEX RE2O3CL2(PPH3)2(C3H2N3O2)2

J. Zubieta, D. J. Rose, K. Maresca, 1997 .

Target occupancy study and whole-body dosimetry with a MAGL PET ligand [11C]PF-06809247 in non-human primates

R. Carson, C. Halldin, A. Takano, 2021, EJNMMI Research.

Bridging the gap between in vitro and in vivo imaging: isostructural Re and 99mTc complexes for correlating fluorescence and radioimaging studies.

J. Brennan, J. Zubieta, J. Lemon, 2004, Journal of the American Chemical Society.

Single Amino Acid Chelates (SAAC): A Strategy for the Design of Technetium and Rhenium Radiopharmaceuticals

J. Zubieta, J. Valliant, J. Babich, 2009 .

New Directions in the Coordination Chemistry of 99mTc: A Reflection on Technetium Core Structures and a Strategy for New Chelate Design

J. Zubieta, J. Valliant, S. Banerjee, 2005 .

Procédé de production d'hétérodimères d'acide glutamique

J. Babich, K. Maresca, C. Zimmerman, 2010 .

Novel polar single amino acid chelates for technetium-99m tricarbonyl-based radiopharmaceuticals with enhanced renal clearance: application to octreotide.

W. Eckelman, J. Marquis, J. Babich, 2010, Bioconjugate chemistry.

Identification and development of an irreversible monoacylglycerol lipase (MAGL) positron emission tomography (PET) radioligand with high specificity.

C. Halldin, A. Takano, Patrick E. Trapa, 2019, Journal of medicinal chemistry.

Synthesis, characterization, and biodistribution of a Technetium-99m ‘3+1’ fatty acid derivative. The crystal and molecular structures of a series of oxorhenium model complexes

A. Fischman, J. Zubieta, T. Shoup, 2002 .

Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.

Jeffrey R. Chabot, P. Loria, C. Halldin, 2017, Angewandte Chemie.

Phase-1 Clinical Trial Results of High-Specific-Activity Carrier-Free 123I-Iobenguane

N. Petry, J. Babich, M. Stabin, 2014, The Journal of Nuclear Medicine.

Phase-1 Clinical Trial Results of High-Specific-Activity Carrier-Free 123 I-Iobenguane

N. Petry, J. Babich, M. Stabin, 2014 .

Bifunctional single amino acid chelates for labeling of biomolecules with the {Tc(CO)3}+ and {Re(CO)3}+ cores. Crystal and molecular structures of [ReBr(CO)3(H2NCH2 C5H4N)], [Re(CO)3{(C5H4 NCH2)2NH}]Br,

J. Zubieta, Lihui Wei, J. Valliant, 2002 .

Synthesis and characterization of oxorhenium-`3 + 1' mixed-thiolate complexes. Crystal and molecular structures of [ReO{η3-(SCH2CH2)2S}(C6H4X-4-CH2S)] (X = F, Cl, Br, OMe) and of the pendant thiolate compounds [ReO{η3-(SCH2CH2)2S}(η1-SCH2CH2SCH2CH2SH)] and [ReO{η3-(SCH2CH2)2S}{η1-SCH2CH(OH)CH(OH)CH2

J. Zubieta, J. Babich, K. Maresca, 1999 .

Electrochemical synthesis of cobalt, nickel, copper, zinc and cadmium complexes with N[(2-hydroxyphenyl)methylidine]-N′-tosylbenzene-1,2-diamine. The crystal structures of {(1,10-phenanthroline)[N-(2-oxophenyl)methylidine]-N-tosylbenzene-1,2-diaminato} nickel(II) and {(1,10-phenanthroline)[N-(2-oxop

J. Zubieta, D. J. Rose, A. Sousa-Pedrares, 1999 .

Synthesis and characterization of complexes of the {ReO} core with SNS and S donor ligands.

J. Zubieta, T. Shoup, J. Babich, 2000, Inorganica chimica acta.

Cationic complexes of the ‘3+1’ oxorhenium–thiolate family

J. Zubieta, J. Babich, K. Maresca, 2000 .

Synthesis and Characterization of Rhenium Thiolate Complexes. Crystal and Molecular Structures of [NBu4][ReO(H2O)Br4)]·2H2O, [Bu4N][ReOBr4(OPPh3)], [ReO(SC5H4N)3], [ReO(SC4H3N2)3][ReO(OH)(SC5H4N-3,6-(SiMe2But)2)2], [Re(N2COC6H5)(SC5H4N)Cl(PPh3)2], and [Re(PPh3)(SC4H3N2)3]

J. Zubieta, M. Abrams, D. J. Rose, 1996 .

Novel ether-containing ligands as potential 99mtechnetium(I) heart agents

J. Zubieta, J. Babich, K. Maresca, 2007 .

Electrochemical synthesis and characterisation of gallium, indium and thallium compounds with 1-hydroxopyridine-2-thione. The crystal structures of tris (1-oxopyridine-2-thionato) indium (III) and tris (1-oxopyridine-2-thionato) thallium (III)

J. Zubieta, D. J. Rose, J. Romero, 1998 .

Single amino acid chelates (SAAC): a strategy for the design of technetium and rhenium radiopharmaceuticals.

J. Zubieta, J. Valliant, M. Bartholomä, 2009, Chemical communications.

A convenient solid-phase synthesis methodology for preparing peptide-derived molecular imaging agents Synthesis, characterization, and in vitro screening of Tc(I) chemotactic peptide conjugates

J. Zubieta, J. Valliant, N. McFarlane, 2005 .

Synthesis and Structural Characterization of Neutral Silver(I) Complexes with Arenephosphinothiols. Crystal Structures of [Ag4{2-(Ph2P)-6-(Me3Si)C6H6S}4] and [Ag4{2-(Ph2PO)-6-(Me3Si)C6H3S}4]

J. Zubieta, J. Romero, J. García-Vázquez, 1999 .

Synthesis and Characterization of Rhenium Phosphinothiolate Complexes. Crystal and Molecular Structures of [HNEt3][Re{P(C6H4S)3}2], [ReOCl{OP(C6H5)2(C6H4S)}{(P(C6H5)2(C6H4S)}], [Re2O5{P(C6H5)2(C6H4S)}2], and [ReOCl{OP(C6H5)2(2-SC6H3-3-SiMe3)}2]

J. Zubieta, D. J. Rose, J. Romero, 1998 .

N,N-bis(2-mercaptoethyl)methylamine: a new coligand for Tc-99m labeling of hydrazinonicotinamide peptides.

A. Fischman, J. Zubieta, J. Valliant, 2005, Bioconjugate chemistry.

Synthesis of bis-thiolato-bridged ru(III) dimers. The crystal structure of [Ru(H2edta)(mu-SC6H5)]2.

J. Zubieta, G. Bridger, K. Maresca, 2000, Inorganic chemistry.

First-in-Man Evaluation of 2 High-Affinity PSMA-Avid Small Molecules for Imaging Prostate Cancer

William C. Eckelman, James B. Stubbs, Stanley J. Goldsmith, 2013, The Journal of Nuclear Medicine.

123I-MIP-1072, a Small-Molecule Inhibitor of Prostate-Specific Membrane Antigen, Is Effective at Monitoring Tumor Response to Taxane Therapy

W. Eckelman, J. Marquis, J. Babich, 2011, The Journal of Nuclear Medicine.

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo

John W. Chen, G. Wojtkiewicz, L. Buckbinder, 2019, Proceedings of the National Academy of Sciences.

Preclinical Evaluation of 89Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy

P. Rejto, L. Chen, J. Hardwick, 2021, Molecular Imaging and Biology.

Synthesis and Characterization of Zinc and Cadmium Compounds with Arenephosphinothiol Ligands. Crystal and Molecular Structures of [Cd2{2-(Ph2PO)C6H4S}4], [Zn{2-(Ph2P)-6-(Me3Si)C6H3S}2], [Cd{2-(Ph2PO)-6-(Me3Si)C6H3S}2(CH3OH)], and [Zn{PhPO(C6H4S-2)2}(bipy)]

J. Zubieta, J. Romero, J. García-Vázquez, 1999 .

First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B

C. Halldin, P. Zanotti-Fregonara, S. Zoghbi, 2022, The Journal of Nuclear Medicine.

Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition

A. Kalgutkar, L. Buckbinder, E. Keliher, 2019, PloS one.

Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction

John W. Chen, G. Wojtkiewicz, L. Buckbinder, 2023, International journal of molecular sciences.

Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer.

Martin G Pomper, William C Eckelman, John W Babich, 2009, Cancer research.

Isostructural Re and 99mTc complexes of biotin derivatives for fluorescence and radioimaging studies.

J. Zubieta, L. Doering, J. Valliant, 2006, Bioconjugate chemistry.

99mTc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen: Pharmacokinetics and Biodistribution Studies in Healthy Subjects and Patients with Metastatic Prostate Cancer

S. Vallabhajosula, J. Osborne, S. Tagawa, 2014, The Journal of Nuclear Medicine.

Direct reductive alkylation of amino acids: Synthesis of bifunctional chelates for nuclear imaging

J. Zubieta, S. Banerjee, J. Babich, 2004 .

Extension of the single amino acid chelate concept (SAAC) to bifunctional biotin analogues for complexation of the M(CO)3(+1) Core (M = Tc and Re): syntheses, characterization, biotinidase stability, and avidin binding.

J. Zubieta, J. Valliant, W. Eckelman, 2006, Bioconjugate chemistry.

Synthesis and Characterization of Organohydrazino Complexes of Technetium, Rhenium, and Molybdenum with the {M(eta(1)-H(x)()NNR)(eta(2)-H(y)()NNR)} Core and Their Relationship to Radiolabeled Organohydrazine-Derivatized Chemotactic Peptides with Diagnostic Applications.

Alun G. Jones, A. Fischman, J. Zubieta, 1998, Inorganic chemistry.

Synthesis and Characterization of Indium Compounds with Phosphinothiol Ligands. The Crystal and Molecular Structures of [In{2-(Ph2P)C6H4S}3], [In{2-(Ph2P)-6-(Me3Si)C6H3S}2{2-(Ph2PO)-6-(Me3Si)C6H3S}], and [NMe4][In{PhP(C6H4S-2)2}2]·CH3CN

J. Zubieta, J. Romero, J. García-Vázquez, 1999 .

The synthesis and characterization of [MCl3(NNC5H4NH) (HNNC5H4N) from [MO4]− (where MRe, Tc) organodiazenido, organodiazene-chelate complexes. The X-ray structure of [ReCl3 (NNC5H4NH) (HNNC5H4N)]

Alun G. Jones, J. Zubieta, D. J. Rose, 1996 .

The synthesis, characterization and X-ray crystal structure of the rhenium organodiazenido, organodiazene complex [ReCl2(PPh3) (NNC5H4N) (HNNC5H4N)]

Alun G. Jones, J. Zubieta, D. J. Rose, 1996 .

Tc-99m labeled small-molecule inhibitors of prostate-specific membrane antigen (PSMA): New molecular imaging probes to detect metastatic prostate adenocarcinoma (PC).

S. Vallabhajosula, J. Osborne, S. Tagawa, 2012, Journal of Clinical Oncology.

Novel polar single amino acid chelates for technetium-99m tricarbonyl-based radiopharmaceuticals with enhanced renal clearance: application to octreotide.

W. Eckelman, J. Marquis, J. Babich, 2010, Bioconjugate chemistry.

Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.

O. Ilkayeva, C. Lang, C. Lynch, 2012, Schizophrenia bulletin.

Targeting metastatic prostate cancer [PCa] in patients with 123I-MIP1072 & 123I-MIP1095

R. Coleman, S. Vallabhajosula, N. Petry, 2009 .

Metastatic Prostate Cancer Pharmacokinetics and Biodistribution Studies in Healthy Subjects and Patients with Tc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen : 99

S. Vallabhajosula, J. Osborne, S. Tagawa, 2014 .

Comprehensive radiolabeling, stability, and tissue distribution studies of technetium-99m single amino acid chelates (SAAC).

J. Zubieta, J. Valliant, S. Banerjee, 2009, Bioconjugate chemistry.

Synthesis and Evaluation of a Series of 99mTc(CO)3+ Lisinopril Complexes for In Vivo Imaging of Angiotensin-Converting Enzyme Expression

V. Dilsizian, W. Eckelman, J. Babich, 2008, Journal of Nuclear Medicine.