K. Baidoo

发表

Preclinical evaluation of a monoclonal antibody targeting the epidermal growth factor receptor as a radioimmunodiagnostic and radioimmunotherapeutic agent

M. Brechbiel, D. Milenic, D. Milenic, 2009, British journal of pharmacology.

Novel bimodal bifunctional ligands for radioimmunotherapy and targeted MRI.

M. Brechbiel, D. Milenic, D. Cheng, 2008, Bioconjugate chemistry.

Cetuximab: preclinical evaluation of a monoclonal antibody targeting EGFR for radioimmunodiagnostic and radioimmunotherapeutic applications.

M. Brechbiel, D. Milenic, K. Garmestani, 2008, Cancer biotherapy & radiopharmaceuticals.

Mapping biological behaviors by application of longer-lived positron emitting radionuclides.

M. Brechbiel, K. Baidoo, Yang Zhou, 2013, Advanced drug delivery reviews.

Imaging pulmonary emboli and deep venous thrombi with 99mTc-bitistatin, a platelet-binding polypeptide from viper venom.

L. Knight, A. Maurer, J. Gabriel, 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Single Photon, Gamma Emitting Radiotracers for Use in Imaging

Alan A. Wilson, H. Burns, K. Baidoo, 1993 .

Molecular Pathways: Targeted α-Particle Radiation Therapy

M. Brechbiel, K. Baidoo, K. Yong, 2012, Clinical Cancer Research.

Preclinical Evaluation of 86Y-Labeled Inhibitors of Prostate-Specific Membrane Antigen for Dosimetry Estimates

M. Brechbiel, M. Pomper, S. Banerjee, 2015, The Journal of Nuclear Medicine.

Mechanisms of Cell Killing Response from Low Linear Energy Transfer (LET) Radiation Originating from 177Lu Radioimmunotherapy Targeting Disseminated Intraperitoneal Tumor Xenografts

M. Brechbiel, D. Milenic, K. Baidoo, 2016, International journal of molecular sciences.

Molecular Pathways Molecular Pathways : Targeted a-Particle Radiation Therapy

M. Brechbiel, K. Baidoo, K. Yong, 2013 .

Impact of α-Targeted Radiation Therapy on Gene Expression in a Pre-Clinical Model for Disseminated Peritoneal Disease when Combined with Paclitaxel

M. Brechbiel, D. Milenic, K. Baidoo, 2014, PloS one.

Sensitization of tumor to ²¹²Pb radioimmunotherapy by gemcitabine involves initial abrogation of G2 arrest and blocked DNA damage repair by interference with Rad51.

M. Brechbiel, D. Milenic, K. Baidoo, 2013, International journal of radiation oncology, biology, physics.

Evaluation of cetuximab as a candidate for targeted α-particle radiation therapy of HER1-positive disseminated intraperitoneal disease

M. Brechbiel, D. Milenic, K. Baidoo, 2015, mAbs.

Preparation, Biological Evaluation, and Pharmacokinetics of the Human Anti-HER1 Monoclonal Antibody Panitumumab Labeled with 86Y for Quantitative PET of Carcinoma

T. Nayak, M. Brechbiel, D. Milenic, 2010, Journal of Nuclear Medicine.

PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A″-DTPA-cetuximab

T. Nayak, M. Brechbiel, D. Milenic, 2010, European Journal of Nuclear Medicine and Molecular Imaging.

Exploration of a F(ab')2 Fragment as the Targeting Agent of α-Radiation Therapy: A Comparison of the Therapeutic Benefit of Intraperitoneal and Intravenous Administered Radioimmunotherapy.

M. Brechbiel, D. Milenic, K. Baidoo, 2018, Cancer biotherapy & radiopharmaceuticals.

Synthesis and characterization of gadolinium-Peptidomimetic complex as an αvβ3 integrin targeted MR contrast agent.

M. Brechbiel, J. Frank, B. Lewis, 2015, Bioorganic & medicinal chemistry letters.

Methodology for labeling proteins and peptides with lead-212 (212Pb).

M. Brechbiel, D. Milenic, K. Baidoo, 2013, Nuclear medicine and biology.

Toward preparation of antibody-based imaging probe libraries for dual-modality positron emission tomography and fluorescence imaging.

P. Choyke, M. Brechbiel, K. Baidoo, 2009, Bioorganic & medicinal chemistry.

A novel bifunctional maleimido CHX-A'' chelator for conjugation to thiol-containing biomolecules.

M. Brechbiel, K. Baidoo, Karen J. Wong, 2008, Bioorganic & medicinal chemistry letters.

Toxicological Studies of 212Pb Intravenously or Intraperitoneally Injected into Mice for a Phase 1 Trial

M. Brechbiel, A. Molinolo, D. Milenic, 2015, Pharmaceuticals.

In vitro and in vivo pre-clinical analysis of a F(ab')2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers

T. Nayak, M. Brechbiel, D. Milenic, 2011, EJNMMI research.

Comparative studies on the therapeutic benefit of targeted α-particle radiation therapy for the treatment of disseminated intraperitoneal disease.

M. Brechbiel, D. Milenic, K. Baidoo, 2017, Dalton transactions.

Targeted α-Particle Radiation Therapy of HER1-Positive Disseminated Intraperitoneal Disease: An Investigation of the Human Anti-EGFR Monoclonal Antibody, Panitumumab

M. Brechbiel, D. Milenic, K. Baidoo, 2017, Translational oncology.

Design, synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging.

P. Choyke, M. Brechbiel, D. Milenic, 2007, Journal of medicinal chemistry.

Targeting HER2

T. Nayak, M. Brechbiel, D. Milenic, 2010, mAbs.

Sodium Fluoride-18 and Radium-223 Dichloride Uptake Colocalize in Osteoblastic Mouse Xenograft Tumors.

Michael V. Green, P. Choyke, J. Seidel, 2021, Cancer biotherapy & radiopharmaceuticals.

An Efficient Bifunctional Decadentate Ligand 3p- C -DEPA for Targeted Alpha Radioimmunotherapy Applications

D. Milenic, K. Baidoo, Hyun A. Song, 2011 .

Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling.

M. Brechbiel, D. Milenic, C. Lai, 2008, Bioconjugate chemistry.

Pre-Clinical Assessment of 177Lu-Labeled Trastuzumab Targeting HER2 for Treatment and Management of Cancer Patients with Disseminated Intraperitoneal Disease

M. Brechbiel, P. Albert, D. Milenic, 2011, Pharmaceuticals.

Gene expression profiling upon 212Pb-TCMC-trastuzumab treatment in the LS-174T i.p. xenograft model

M. Brechbiel, D. Milenic, K. Baidoo, 2013, Cancer medicine.

In vitro and in vivo pre-clinical analysis of a F ( ab ’ ) 2 fragment of panitumumab for molecular imaging and therapy of HER 1-positive cancers

T. Nayak, M. Brechbiel, D. Milenic, 2011 .

H2BZmacropa-NCS: A Bifunctional Chelator for Actinium-225 Targeted Alpha Therapy.

Justin J. Wilson, F. Escorcia, K. Baidoo, 2022, Bioconjugate chemistry.

Preclinical evaluation of NETA-based bifunctional ligand for radioimmunotherapy applications using 212Bi and 213Bi: radiolabeling, serum stability, and biodistribution and tumor uptake studies.

M. Brechbiel, D. Milenic, K. Baidoo, 2013, Nuclear medicine and biology.

Efficient bifunctional decadentate ligand 3p-C-DEPA for targeted α-radioimmunotherapy applications.

M. Brechbiel, D. Milenic, K. Baidoo, 2011, Bioconjugate chemistry.

Synthesis and biological evaluation of a novel decadentate ligand DEPA.

M. Brechbiel, D. Milenic, K. Baidoo, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and characterization of αvβ₃-targeting peptidomimetic chelate conjugates for PET and SPECT imaging.

M. Brechbiel, D. Milenic, K. Baidoo, 2012, Bioorganic & medicinal chemistry letters.

Abstract 1601: Paclitaxel potentiates212Pb-radioimmunotherapy-induced cell killing efficacy by perturbing mitotic spindle checkpoint.

M. Brechbiel, D. Milenic, K. Baidoo, 2013 .

Evaluation of platinum chemotherapy in combination with HER2-targeted α-particle radiation.

M. Brechbiel, J. Shih, D. Milenic, 2013, Cancer biotherapy & radiopharmaceuticals.

Preclinical Evaluation of 203/212Pb-Labeled Low-Molecular-Weight Compounds for Targeted Radiopharmaceutical Therapy of Prostate Cancer

M. Brechbiel, M. Pomper, C. Brayton, 2020, The Journal of Nuclear Medicine.

Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and 212Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model

M. Brechbiel, D. Milenic, K. Baidoo, 2016, PloS one.

Synthesis and evaluation of a bifunctional chelate for development of Bi(III)-labeled radioimmunoconjugates.

M. Brechbiel, K. Baidoo, Hyun A. Song, 2011, Bioorganic & medicinal chemistry letters.

Increases the Ratio of T + Vaccine-Mediated Antigen-Specific CD 8 IL-2 / Anti-IL-2 Antibody Complex Enhances

J. Schlom, H. Sabzevari, D. Milenic, 2008 .

(111)In- and (203)Pb-Labeled Cyclic RGD Peptide Conjugate as an α(v)β(3) Integrin-Binding Radiotracer.

M. Brechbiel, D. Milenic, K. Baidoo, 2012, Journal of labelled compounds & radiopharmaceuticals.

(2S)-2-(3-(1-Carboxy-5-(4-211At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy

M. Brechbiel, M. Pomper, M. Zalutsky, 2016, The Journal of Nuclear Medicine.

Towards the stable chelation of radium for biomedical applications with an 18-membered macrocyclic ligand†

Justin J. Wilson, F. Escorcia, D. Abou, 2021, Chemical science.

Unexpected Behavior of the Heaviest Halogen Astatine in the Nucleophilic Substitution of Aryliodonium Salts.

M. Brechbiel, K. Baidoo, J. Gestin, 2016, Chemistry.

99mTcLabeling of Proteins: Initial Evaluation of a Novel Diaminedithiol Bifunctional Chelating Agent1

U. Scheffel, K. Baidoo, S. Z. Lever, 2006 .

A new high affinity technetium-99m-bombesin analogue with low abdominal accumulation.

M. Pomper, M. Carducci, H. Wagner, 2005, Bioconjugate chemistry.

Synthesis of a novel bifunctional chelate designed for labeling proteins with technetium-99m

H. Burns, A. Kramer, K. Baidoo, 1988 .

Synthesis and in vivo evaluation of a 99m/99Tc-DADT-benzovesamicol: a potential marker for cholinergic neurons.

K. Baidoo, D. Wieland, Y. Jung, 1994, Nuclear medicine and biology.

212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint

M. Brechbiel, D. Milenic, K. Baidoo, 2013, British Journal of Cancer.

In Vivo Imaging of Peripheral Benzodiazepine Receptors in Mouse Lungs: A Biomarker of Inflammation

T. Guilarte, M. Pomper, Ming-Kai Chen, 2005, Molecular imaging.

A STUDY OF 219Rn OUTGASSING AND 211Pb CONTAMINATION FROM 223Ra IN DRY, LIQUID, AND MURINE TISSUE SAMPLES.

P. Choyke, J. Seidel, J. Roy, 2020, Health physics.

Pulmonary accumulation of neutral diamine dithiol complexes of technetium-99m.

H. Wagner, U. Scheffel, K. Baidoo, 1994, Journal of pharmaceutical sciences.

PET imaging of tumor angiogenesis in mice with VEGF‐A–targeted 86Y‐CHX‐A″‐DTPA‐bevacizumab

T. Nayak, M. Brechbiel, D. Milenic, 2011, International journal of cancer.

Quantitative PET imaging of cancer using the human anti-HER1 monoclonal antibody, panitumumab labeled with Y86

M. Brechbiel, D. Milenic, K. Garmestani, 2009 .

Upregulation of Somatostatin Receptor Type 2 in a Receptor-Deficient In Vivo Pancreatic Neuroendocrine Tumor Model Improves Tumor Response to Targeted 177Lu-DOTATATE

F. Escorcia, M. Zeiger, S. Sadowski, 2022, bioRxiv.

99 mTcLabeling of Proteins : Initial Evaluation of a Novel Diaminedithiol Bifunctional Chelating Agent 1

U. Scheffel, K. Baidoo, S. Z. Lever, 2006 .

A novel side-bridged hybrid phosphonate/acetate pendant cyclam: synthesis, characterization, and 64Cu small animal PET imaging.

M. Brechbiel, D. Milenic, C. Lai, 2009, Bioorganic & medicinal chemistry.

Multimodality Therapy: Potentiation of High Linear Energy Transfer Radiation with Paclitaxel for the Treatment of Disseminated Peritoneal Disease

M. Brechbiel, P. Albert, D. Milenic, 2008, Clinical Cancer Research.

Design and synthesis of a versatile precursor to neutral technetium and rhenium complexes

K. Baidoo, S. Z. Lever, 1990 .

Structure proof of syn/anti isomerism in N-alkylated diaminedithiol (DADT) complexes of technetium

A. Mahmood, K. Baidoo, S. Z. Lever, 1990 .

Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria

Bert Vogelstein, Kenneth W. Kinzler, Chetan Bettegowda, 2003, Proceedings of the National Academy of Sciences of the United States of America.

HER1-Targeted 86Y-Panitumumab Possesses Superior Targeting Characteristics than 86Y-Cetuximab for PET Imaging of Human Malignant Mesothelioma Tumors Xenografts

T. Nayak, M. Brechbiel, D. Milenic, 2011, PloS one.

ImmunoPET as Stoichiometric Sensor for Glypican-3 in Models of Hepatocellular Carcinoma

Mitchell Ho, P. Choyke, F. Escorcia, 2020, bioRxiv.

212Pb-Radioimmunotherapy Induces G2 Cell-Cycle Arrest and Delays DNA Damage Repair in Tumor Xenografts in a Model for Disseminated Intraperitoneal Disease

M. Brechbiel, D. Milenic, K. Baidoo, 2012, Molecular Cancer Therapeutics.

IL-2/Anti-IL-2 Antibody Complex Enhances Vaccine-Mediated Antigen-Specific CD8+ T Cell Responses and Increases the Ratio of Effector/Memory CD8+ T Cells to Regulatory T Cells1

J. Schlom, H. Sabzevari, D. Milenic, 2008, The Journal of Immunology.

ImmunoPET Predicts Response to Met-targeted Radioligand Therapy in Models of Pancreatic Cancer Resistant to Met Kinase Inhibitors

Jason S. Lewis, F. Escorcia, K. Baidoo, 2020, Theranostics.

Title : ImmunoPET Predicts Response to Met-targeted Radioligand Therapy in 1 Models of Pancreatic Cancer Resistant to Met Kinase Inhibitors 2 3

Jason S. Lewis, F. Escorcia, K. Baidoo, 2019 .

Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization.

T. Guilarte, Ming-Kai Chen, T. Verina, 2004, Brain : a journal of neurology.

Glypican-3-Targeted Alpha Particle Therapy for Hepatocellular Carcinoma

P. Choyke, F. Escorcia, K. Baidoo, 2020, Molecules.

225Ac-MACROPATATE: A Novel α-Particle Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors

Justin J. Wilson, F. Escorcia, S. Sadowski, 2022, The Journal of Nuclear Medicine.

Design and synthesis of a short-chain bitistatin analogue for imaging thrombi and emboli.

L. Knight, J. Gabriel, K. Baidoo, 2004, Bioconjugate chemistry.

A new high affinity technetium analogue of bombesin containing DTPA as a pharmacokinetic modifier.

M. Pomper, M. Carducci, H. Wagner, 2004, Bioconjugate chemistry.

Bench to Bedside: Stability Studies of GMP Produced Trastuzumab-TCMC in Support of a Clinical Trial

M. Brechbiel, D. Milenic, K. Baidoo, 2015, Pharmaceuticals.

In Vitro and In Vivo Analysis of Indocyanine Green-Labeled Panitumumab for Optical Imaging—A Cautionary Tale

M. Brechbiel, D. Milenic, K. Baidoo, 2014, Bioconjugate chemistry.

Development of Iodinated Indocyanine Green Analogs as a Strategy for Targeted Therapy of Liver Cancer

Sierra C. Marker, F. Escorcia, K. Baidoo, 2023, ACS Medicinal Chemistry Letters.

Tc-99m tricarbonyl labeling of DTPA-bitistatin for imaging thrombi and emboli

M. Marmion, L. Knight, K. Baidoo, 2000 .

Site-Specifically Conjugated Single-Domain Antibody Successfully Identifies Glypican-3–Expressing Liver Cancer by Immuno-PET

Mitchell Ho, F. Escorcia, Ross W. Cheloha, 2023, The Journal of Nuclear Medicine.