W. Newman

发表

Role of HMGB1 in apoptosis-mediated sepsis lethality

K. Tracey, Huan Yang, Haichao Wang, 2006, The Journal of Experimental Medicine.

Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules

F. Luscinskas, M. Gimbrone, R. Schleimer, 1991, The Journal of experimental medicine.

Role of HMGB1 in apoptosis-mediated sepsis lethality.

K. Tracey, Huan Yang, Haichao Wang, 2006, The Journal of experimental medicine.

Circulating adhesion molecules in disease.

A. Gearing, W. Newman, A. Gearing, 1993, Immunology today.

T cells bind to cytokine-activated endothelial cells via a novel, inducible sialoglycoprotein and endothelial leukocyte adhesion molecule-1.

T. V. Gopal, W. Newman, N. Graber, 1990, Journal of immunology.

Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion

K. Horgan, W. Newman, Y. Shimizu, 1992, The Journal of experimental medicine.

IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1.

F. Luscinskas, M. Gimbrone, R. Schleimer, 1992, Journal of immunology.

Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue.

C. Mackay, E. Butcher, W. Newman, 1997, The American journal of pathology.

Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism

J. Wolchok, J. Meyerson, T. Merghoub, 2022, Science advances.

Kinetic expression of endothelial adhesion molecules and relationship to leukocyte recruitment in two cutaneous models of inflammation.

K. Reimann, W. Newman, D. Ringler, 1994, Laboratory investigation; a journal of technical methods and pathology.

Title: mDKN-01, a Novel Anti-DKK1 Monoclonal Antibody, Enhances Innate Immune Responses in the Tumor Microenvironment

M. Kagey, W. Newman, J. Rottman, 2020 .

Dickkopf-1 Can Lead to Immune Evasion in Metastatic Castration-Resistant Prostate Cancer.

P. Nelson, N. Schultz, S. Larson, 2020, JCO precision oncology.

mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment

M. Kagey, W. Newman, J. Rottman, 2020, Molecular Cancer Research.

Dendritic cell activating peptides induce distinct cytokine profiles.

K. Tracey, Huan Yang, N. Chiorazzi, 2006, International immunology.

Monocyte Adhesion to Endothelium in Simian Immunodeficiency Virus-Induced AIDS Encephalitis Is Mediated by Vascular Cell Adhesion Molecule-1 1a4f31 I ntegrin Interactions

V. Sasseville, W. Newman, S. Brodie, 2007 .

Rational design of anti-GITR-based combination immunotherapy

J. Wolchok, V. Velcheti, M. Hellmann, 2019, Nature Medicine.

Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism

J. Wolchok, J. Meyerson, T. Merghoub, 2022, Science advances.

Eotaxin and CCR3 are up‐regulated in exacerbations of chronic bronchitis

D. Olivieri, W. Newman, G. Bertorelli, 2002, Allergy.

Differences between human eosinophils and neutrophils in the function and expression of sialic acid-containing counterligands for E-selectin.

W. Newman, B. Bochner, S. A. Sterbinsky, 1994, Journal of immunology.

Monocyte adhesion to endothelium in simian immunodeficiency virus-induced AIDS encephalitis is mediated by vascular cell adhesion molecule-1/alpha 4 beta 1 integrin interactions.

V. Sasseville, W. Newman, S. Brodie, 1994, The American journal of pathology.

Identical expression of ELAM‐1, VCAM‐1, and ICAM‐1 in sarcoidosis and usual interstitial pneumonitis

C. Meijer, C. Meijer, W. Newman, 1993, The Journal of pathology.

Heterogeneity of human natural killer recognition demonstrated by cloned effector cells and differential blocking of cytotoxicity with monoclonal antibodies.

P. Wernet, G. Pawelec, W. Newman, 1985, Cellular immunology.

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

Ying Sun, Nancy Sullivan, Joseph Sodroski, 1996, Cell.

AdhesionofHuman B CellstoFollicular Dendritic CellsInvolvesboththeLymphocyte Function-associated Antigen 1/Intercellular Adhesion Molecule1 and VeryLateAntigen4/VascularCell AdhesionMolecule1 Pathways

H. Schuurman, W. Newman, S. Pals, 1991 .

Is the NK lytic process involved in the mechanism of NK suppression of antibody-producing cells?

S. Targan, R. Stevens, W. Newman, 1985, Journal of immunology.

HMGB1 SIGNALS THROUGH TOLL‐LIKE RECEPTOR 2.: 40

K. Tracey, Huan Yang, C. Czura, 2004 .

Interleukin 2 induces gamma-interferon production: participation of macrophages and NK-like cells.

I. Kawase, W. Newman, C. Henney, 1983, Journal of immunology.

The mechanism of augmentation of natural killer cell activity by syngeneic tumor cells: Role of macrophage‐derived factor in NK boosting

I. Kawase, W. Newman, C. Henney, 1983, International journal of cancer.

Evidence for T cell nature and heterogeneity within natural killer (NK) and antibody-dependent cellular cytotoxicity (ADCC) effectors: a comparison with cytolytic T lymphocytes (CTL).

J. Hansen, W. Newman, L. Fast, 1981, Journal of immunology.

Elevated vascular cell adhesion molecule-1 in AIDS encephalitis induced by simian immunodeficiency virus.

V. Sasseville, A. Lackner, W. Newman, 1992, The American journal of pathology.

Early events in lymphocyte activation as defined by three new monoclonal antibodies.

W. Newman, P. Rao, E. Patten, 1986, Journal of immunology.

Identification and functional characterization of two distinct epitopes on the human T cell surface protein Tp50.

G. Longton, J. Ledbetter, J. Hansen, 1983, Journal of immunology.

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5

Joseph Sodroski, Cristina Parolin, J. Sodroski, 1996, Nature.

CCR5 Levels and Expression Pattern Correlate with Infectability by Macrophage-tropic HIV-1, In Vitro

Nancy Sullivan, Joseph Sodroski, J. Sodroski, 1997, The Journal of experimental medicine.

Discrete Steps in Binding and Signaling of Interleukin-8 with Its Receptor*

C. Mackay, W. Newman, Lijun Wu, 1996, The Journal of Biological Chemistry.

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

J. Sodroski, C. Mackay, W. Hofmann, 1997, Nature.

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils

C. Mackay, W. Newman, C. Gerard, 1996, The Journal of experimental medicine.

Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines.

Hao Li, J. White, R. Schleimer, 1997, The Journal of clinical investigation.

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.

W Newman, C. Mackay, J. Gutiérrez-Ramos, 1996, The Journal of clinical investigation.

Activation-independent binding of human memory T cells to adhesion molecule ELAM-1

W. Newman, Y. Shimizu, S. Shaw, 1991, Nature.

Decreased expression of IL-2 in central and effector CD4 memory cells during progression to AIDS in rhesus macaques

V. Maino, J. Heeney, H. Niphuis, 2001, AIDS.

Multi-recognition capability of E-selectin in a dynamic flow system, as evidenced by differential effects of sialidases and anti-carbohydrate antibodies on selectin-mediated cell adhesion at low vs. high wall shear stress: a preliminary note.

K. Handa, S. Hakomori, W. Newman, 1992, Biochemical and biophysical research communications.

Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells.

K. Handa, S. Hakomori, W. Newman, 1992, Biochemical and biophysical research communications.

Blockade of NK cell lysis is a property of monoclonal antibodies that bind to distinct regions of T-200.

W. Newman, L. Fast, L. Rose, 1983, Journal of immunology.

Definition of a "trigger" stage in the NK cytolytic reaction sequence by a monoclonal antibody to the glycoprotein T-200.

S. Targan, W. Newman, 1983, Journal of immunology.

Selective blockade of human natural killer cells by a monoclonal antibody.

W. Newman, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Production of migration inhibition factor (MIF) and an inducer of plasminogen activator (IPA) by subsets of T cells in MLC.

S. Gordon, B. Bloom, U. Hämmerling, 1978, Journal of immunology.

Effects of fucose-binding lectins and Tuftsin on the migration of guinea pig peritoneal exudate cells☆☆☆

B. Bloom, P. Satoh, W. Newman, 1976 .

Macrophage proteases and rheumatic diseases: Regulation of plasminogen activator by thymus-derived lymphocytes

S. Gordon, B. Bloom, W. Newman, 2005, Agents and Actions.

Vascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro.

W. Newman, J. Madri, J. Merwin, 1991, The American journal of pathology.

Validation of a DKK1 RNAscope chromogenic in situ hybridization assay for gastric and gastroesophageal junction adenocarcinoma tumors

V. Adisetiyo, M. Kagey, W. Newman, 2021, Scientific Reports.

Structural and functional studies of full-length vascular cell adhesion molecule-1: internal duplication and homology to several adhesion proteins.

T. V. Gopal, G. Raghunathan, W. Newman, 1991, DNA and cell biology.

Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.

W. Newman, S. Pals, Y. Shimizu, 1994, Journal of immunology.

Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239

J. Sodroski, M. Farzan, L. Wu, 1997, Journal of virology.

The α-Chemokine, Stromal Cell-derived Factor-1α, Binds to the Transmembrane G-protein-coupled CXCR-4 Receptor and Activates Multiple Signal Transduction Pathways*

R. Ganju, J. Groopman, W. Newman, 1998, The Journal of Biological Chemistry.

Primary in vitro sensitisation of human T cells

B. Bloom, W. Newman, G. Stoner, 1977, Nature.

Human Eotaxin Induces α4 and β2 Integrin-Dependent Eosinophil Accumulation in Rat Skin In Vivo: Delayed Generation of Eotaxin in Response to IL-4

C. Mackay, S. Nourshargh, T. Williams, 1998, The Journal of Immunology.

in Response to IL-4 Rat Skin In Vivo: Delayed Generation of Eotaxin Integrin-Dependent Eosinophil Accumulation in 2 b and 4 a Human Eotaxin Induces

C. Mackay, S. Nourshargh, T. Williams, 1998 .

Inhibition of T cell recruitment and cutaneous delayed-type hypersensitivity-induced inflammation with antibodies to monocyte chemoattractant protein-1.

J. Warren, M. Mansour, W. Newman, 1996, The American journal of pathology.

DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti‐DKK1 therapeutic DKN‐01

J. Pollard, M. Kagey, L. Boulter, 2022, Liver international : official journal of the International Association for the Study of the Liver.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Adhesion of human B cells to follicular dendritic cells involves both the lymphocyte function-associated antigen 1/intercellular adhesion molecule 1 and very late antigen 4/vascular cell adhesion molecule 1 pathways

C. Meijer, H. Schuurman, W. Newman, 1991, The Journal of experimental medicine.

Recruitment of lymphocytes during cutaneous delayed hypersensitivity in nonhuman primates is dependent on E-selectin and vascular cell adhesion molecule 1.

V. Sasseville, W. Newman, D. Pauley, 1994, The Journal of clinical investigation.

Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin alpha 4 beta 7.

C. Mackay, W. Newman, P. Hesterberg, 1996, Gastroenterology.

Full length vascular cell adhesion molecule 1 (VCAM-1).

T. V. Gopal, W. Newman, T. Polte, 1990, Nucleic acids research.

Immunobiological and immunochemical aspects of the T-200 family of glycoproteins.

S. Targan, W. Newman, L. Fast, 1984, Molecular immunology.

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion

Y. Tanaka, S. Albelda, P. Newman, 1992, The Journal of experimental medicine.

Genetic and Functional Studies of Continuous Macrophage-Like Cell Lines

N. Rosen, B. Diamond, R. Muschel, 1980 .

Monoclonal antibodies recognizing human T cells: potential role for preventing graft-versus-host reactions following allogeneic marrow transplantation.

J. Hansen, M. Kamoun, W. Newman, 1981, Transplantation proceedings.

T cell nature and heterogeneity of recognition structures of human natural killer (NK) cells.

J. Hansen, P. Beatty, W. Newman, 1983, Journal of immunology.

Activated human B cells display a functional IL 2 receptor.

W. Newman, R. Mittler, M. Hoffmann, 1985, Journal of immunology.

Identification of anti-CD3 antibodies that do not modulate antigen but induce mitogenesis and block the mixed lymphocyte reaction.

E. Meyer, W. Newman, P. Rao, 1992, Human immunology.

Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK.

R. Ganju, J. Groopman, W. Newman, 1998, Blood.

Rational design of anti-GITR-based combination immunotherapy

J. Wolchok, V. Velcheti, M. Hellmann, 2019, Nature Medicine.

Endothelial activation and circulating vascular adhesion molecules in alcoholic liver disease

D. Adams, E. Elias, P. Burra, 1994, Hepatology.

Safety and efficacy of a DKK1 inhibitor (DKN-01) in combination with pembrolizumab (P) in patients (Pts) with advanced gastroesophageal (GE) malignancies.

M. Kagey, J. Bendell, W. Newman, 2018, Annals of oncology : official journal of the European Society for Medical Oncology.

Regulation of colony-stimulating factor 1-dependent macrophage precursor proliferation by type beta transforming growth factor.

M. Cole, G. Strassmann, W. Newman, 1988, Journal of immunology.

Abstract CT018: Intratumor and peripheral Treg modulation as a pharmacodynamic biomarker of the GITR agonist antibody TRX-518 in the first in-human trial

J. Wolchok, V. Velcheti, M. Callahan, 2017 .

THE USE OF A MONOCLONAL ANTIBODY TO ANALYSE HUMAN NK CELL FUNCTION

W. Newman, 1982 .

Abstract PR01: Mechanistic rationale to combine GITR agonism with PD-1 blockade in cancer patients

J. Wolchok, V. Velcheti, M. Callahan, 2019, Regulating T-cells and Their Response to Cancer.

The Distribution of Lymphocytes Expressing αβ and γδ T-cell Receptors, and the Expression of Mucosal Addressin Cell Adhesion Molecule-1 in the Canine Intestine

P. Moore, W. Newman, M. Day, 1999 .

The link between inflammatory disease and patterns of leukocyte recruitment.

C. Mirabelli, W. Newman, 1998, Expert opinion on investigational drugs.

Multiple activation steps of the N-formyl peptide receptor.

Terri L. Gilbert, L. Sklar, E. Prossnitz, 1999, Biochemistry.

Lymphocyte interactions with endothelial cells.

Y. Tanaka, W. Newman, Y. Shimizu, 1992, Immunology today.

Atriopeptin inhibition ofthrombin-mediated changes inthe morphology andpermeability ofendothelial monolayers

W. Newman, D. Baron, C. E. Lofton, 1989 .

Four molecular pathways of T cell adhesion to endothelial cells: roles of LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions

T. V. Gopal, K. Horgan, W. Newman, 1991, The Journal of cell biology.

CCR5 Levels and Expression Pattern Correlate with Infectability by Macrophage-tropic HIV-1, In Vitro

J. Sodroski, C. Mackay, R. Koup, 1997, The Journal of experimental medicine.

Sequential cutaneous cytokine localization leukocyte endothelial cell adhesion molecule cam expression and leukocyte typing in rhesus monkeys receiving intradermal lps

W. Newman, R. McEver, R. Hunt, 1992 .