J. Hikima

发表

Evolutional Conservation of Molecular Structure and Antiviral Function of a Viral RNA Receptor, LGP2, in Japanese Flounder, Paralichthys olivaceus

I. Hirono, T. Aoki, M. Ohtani, 2010, The Journal of Immunology.

Comparative Sequence Analysis of a Multidrug-Resistant Plasmid from Aeromonas hydrophila

I. Hirono, T. Aoki, H. Takeyama, 2012, Antimicrobial Agents and Chemotherapy.

Innate immune response in the hemolymph of an ascidian, Halocynthia roretzi, showing soft tunic syndrome, using label-free quantitative proteomics.

T. Aoki, J. Hikima, T. Jung, 2011, Developmental and comparative immunology.

BOB.1 of the channel catfish, Ictalurus punctatus: not a transcriptional coactivator?

G. Warr, N. Miller, Melanie R. Wilson, 2009, Molecular immunology.

Characterization of an Oct1 orthologue in the channel catfish, Ictalurus punctatus: A negative regulator of immunoglobulin gene transcription?

G. Warr, N. Miller, Melanie R. Wilson, 2007, BMC molecular biology.

Innate immunity of finfish: primordial conservation and function of viral RNA sensors in teleosts.

T. Aoki, J. Hikima, T. Jung, 2013, Fish & shellfish immunology.

DNA vaccine-mediated innate immune response triggered by PRRs in teleosts

T. Aoki, T. Takano, J. Hikima, 2015, Fisheries Science.

Characterization and gene expression of transcription factors, PU.1 and C/EBPα driving transcription from the tumor necrosis factor α promoter in Japanese flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, M. Ohtani, 2011, Developmental and comparative immunology.

Evolution of Transcriptional Control of the IgH Locus: Characterization, Expression, and Function of TF12/HEB Homologs of the Catfish12

G. Warr, L. Clem, N. Miller, 2004, The Journal of Immunology.

The lysozyme gene in fish

I. Hirono, T. Aoki, J. Hikima, 2002 .

RNA-Seq-Based Metatranscriptomic and Microscopic Investigation Reveals Novel Metalloproteases of Neobodo sp. as Potential Virulence Factors for Soft Tunic Syndrome in Halocynthia roretzi

T. Aoki, J. Hikima, T. Jung, 2012, PloS one.

Inhibition of lysozyme lytic activity by Ivy derived from Photobacterium damselae subsp. piscicida.

J. Hikima, M. Sakai, T. Kono, 2022, Fish & shellfish immunology.

Interleukin-17 Receptor A1 Gene Knockout Causes Weight Loss and Reduction of Intestinal Metabolism-Related Genes in The Japanese Medaka, Oryzias Latipes

Hiroshi Miyanishi, M. Kinoshita, J. Hikima, 2020 .

Draft Genome Sequence of the Fish Pathogen Mycobacterium pseudoshottsii Strain JCM15466, a Species Closely Related to M. marinum

S. Kuhara, K. Tashiro, T. Aoki, 2016, Genome Announcements.

Fish cytokines: current research and applications

J. Hikima, M. Sakai, T. Kono, 2020, Fisheries Science.

Osteichthyes: Immune Systems of Teleosts (Actinopterygii)

T. Yada, J. Hikima, T. Nakanishi, 2018 .

Characterization and function of kuruma shrimp lysozyme possessing lytic activity against Vibrio species.

I. Hirono, T. Aoki, J. Hikima, 2003, Gene.

Comparative Genome Analysis of Fish and Human Isolates of Mycobacterium marinum

I. Hirono, T. Aoki, J. Hikima, 2013, Marine Biotechnology.

Molecular characterization and expression of the teleost cytosolic DNA sensor genes cGAS, LSm14A, DHX9, and DHX36 in Japanese medaka, Oryzias latipes.

J. Hikima, M. Sakai, T. Kono, 2019, Developmental and comparative immunology.

Molecular characterization, expression and functional analysis of a nuclear oligomerization domain proteins subfamily C (NLRC) in Japanese flounder (Paralichthys olivaceus).

Mudjekeewis D. Santos, I. Hirono, T. Aoki, 2011, Fish & shellfish immunology.

a Primitive Teleost Fish ), Oncorhynchus mykiss from Rainbow Trout ( Features in a Primordial CD80/86 Molecule Conservation of Structural and Functional

Yongan Zhang, J. Hikima, J. Sunyer, 2009 .

Transcriptome analysis of immune response against Vibrio harveyi infection in orange‐spotted grouper (Epinephelus coioides)

Pei-Chi Wang, Shih‐Chu Chen, T. Aoki, 2017, Fish & shellfish immunology.

Biology and host response to Cyprinid herpesvirus 3 infection in common carp.

T. Aoki, M. Adamek, D. Steinhagen, 2014, Developmental and comparative immunology.

Developmental and Comparative Immunology

T. Aoki, D. Steinhagen, J. Hikima, 2013 .

The cytosolic sensor, DDX41, activates antiviral and inflammatory immunity in response to stimulation with double-stranded DNA adherent cells of the olive flounder, Paralichthys olivaceus.

T. Aoki, J. Hikima, T. Jung, 2015, Fish & shellfish immunology.

Characterization and antiviral function of a cytosolic sensor gene, MDA5, in Japanese flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, M. Ohtani, 2011, Developmental and comparative immunology.

Molecular cloning and antiviral activity of IFN-β promoter stimulator-1 (IPS-1) gene in Japanese flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, M. Ohtani, 2010, Fish & shellfish immunology.

Complete Genome Sequence and Immunoproteomic Analyses of the Bacterial Fish Pathogen Streptococcus parauberis (cid:1)

I. Hirono, T. Aoki, J. Hikima, 2011 .

Outer Membrane Vesicles as a Candidate Vaccine against Edwardsiellosis

T. Aoki, M. Ohtani, J. Hikima, 2011, PloS one.

Diel rhythm of the inflammatory cytokine il1b in the Japanese medaka (Oryzias latipes) regulated by core components of the circadian clock.

Hiroshi Miyanishi, J. Hikima, M. Sakai, 2022, Fish & shellfish immunology.

Inflammatory responses in the Japanese pufferfish (Takifugu rubripes) head kidney cells stimulated with an inflammasome-inducing agent, nigericin.

J. Hikima, M. Sakai, T. Kono, 2014, Developmental and comparative immunology.

Microarray technology is an effective tool for identifying genes related to the aquacultural improvement of Japanese flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, J. Hikima, 2011, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Characterization and expression analysis of tandemly-replicated asc genes in the Japanese medaka, Oryzias latipes.

J. Hikima, M. Sakai, T. Kono, 2020, Developmental and comparative immunology.

Molecular cloning and functional analysis of nucleotide-binding oligomerization domain 1 (NOD1) in olive flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, Yoshiaki Suzuki, 2012, Developmental and comparative immunology.

Cathepsins in the kidney of olive flounder, Paralichthys olivaceus, and their responses to bacterial infection.

T. Aoki, J. Kwon, J. Hikima, 2012, Developmental and comparative immunology.

Identification and determination of antigenic proteins of Korean ranavirus-1 (KRV-1) using MALDI-TOF/TOF MS analysis.

T. Aoki, A. Eom, M. Ohtani, 2011, Comparative immunology, microbiology and infectious diseases.

Detection of antigenic proteins expressed by lymphocystis virus as vaccine candidates in olive flounder, Paralichthys olivaceus (Temminck & Schlegel).

T. Aoki, M. Ohtani, J. Hikima, 2011, Journal of fish diseases.

Immune responses in the Japanese pufferfish (Takifugu rubripes) head kidney cells stimulated with particulate silica.

T. Morimoto, J. Hikima, M. Sakai, 2016, Fish & shellfish immunology.

Molecular cloning and characterization of Toll-like receptor 3 in Japanese flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, M. Ohtani, 2012, Developmental and comparative immunology.

On-site Direct Detection of Astaxanthin from Salmon Fillet Using Raman Spectroscopy

T. Aoki, H. Takeyama, H. Hamaguchi, 2017, Marine Biotechnology.

Adjuvant effects of poly I:C and imiquimod on the immunization of kuruma shrimp (Marsupenaeus japonicus) with a recombinant protein, VP28 against white spot syndrome virus.

J. Hikima, T. Itami, M. Sakai, 2015 .

Cytosolic Sensors for Pathogenic Viral and Bacterial Nucleic Acids in Fish

M. Chadzińska, J. Hikima, M. Sakai, 2020, International journal of molecular sciences.

Identification and expression of phospholipase A2 genes related to transcriptional control in the interleukin-17A/F1 pathway in the intestines of Japanese medaka Oryzias latipes

Hiroshi Miyanishi, J. Hikima, M. Sakai, 2021, Fish and shellfish Immunology reports.

Characterization of two POU transcription factor family members from the urochordate Oikopleura dioica.

G. Warr, J. Hikima, C. Cunningham, 2006, Gene.

Inductive immune responses in the Japanese pufferfish (Takifugu rubripes) treated with recombinant IFN-γ, IFN-γrel, IL-4/13A and IL-4/13B.

J. Hikima, M. Sakai, T. Kono, 2016, International immunopharmacology.

Characterization of a specific monoclonal antibody against immunoglobulin light kappa/L1 chain in olive flounder (Paralichthys olivaceus)

T. Aoki, J. H. Lee, M. Ohtani, 2017, Fish & shellfish immunology.

Seasonal variation and comparative analysis of non-specific humoral immune substances in the skin mucus of olive flounder (Paralichthys olivaceus).

T. Aoki, J. Hikima, T. Jung, 2012, Developmental and comparative immunology.

Characterization and expression of c-type lysozyme cDNA from Japanese flounder (Paralichthys olivaceus).

I. Hirono, T. Aoki, J. Hikima, 1997, Molecular marine biology and biotechnology.

Inflammasomes in Teleosts: Structures and Mechanisms That Induce Pyroptosis during Bacterial Infection

J. Hikima, M. Sakai, T. Kono, 2021, International journal of molecular sciences.

Comparative analysis and distribution of pP9014, a novel drug resistance IncP-1 plasmid from Photobacterium damselae subsp. piscicida.

I. Hirono, T. Aoki, J. Hikima, 2013, International journal of antimicrobial agents.

Diel Variation in CC Chemokine Gene Expression in the Japanese Pufferfish Takifugu rubripes

J. Hikima, M. Sakai, T. Kono, 2020, Marine Biotechnology.

Comparative Genomic Characterization of Three Streptococcus parauberis Strains in Fish Pathogen, as Assessed by Wide-Genome Analyses

Yoji Nakamura, I. Hirono, T. Aoki, 2013, PloS one.

Detection of Kudoa amamiensis Using Loop-Mediated Isothermal Amplification (LAMP)

J. Hikima, H. Yokoyama, M. Sakai, 2015 .

Multiple Drug-resistant Strains of Aeromonas hydrophila Isolated from Tilapia Farms in Thailand

I. Hirono, T. Aoki, J. Hikima, 2012 .

Expression of Japanese flounder c-type lysozyme cDNA in insect cells.

I. Hirono, T. Aoki, J. Hikima, 2001, Developmental and comparative immunology.

Molecular cloning, expression and evolution of the Japanese flounder goose-type lysozyme gene, and the lytic activity of its recombinant protein.

I. Hirono, T. Aoki, J. Hikima, 2001, Biochimica et biophysica acta.

Molecular Cloning and Novel Repeated Sequences of a C-type Lysozyme Gene in Japanese Flounder (Paralichthys olivaceus)

I. Hirono, T. Aoki, J. Hikima, 2000, Marine Biotechnology.

Detection of Kudoa septempunctata in the Japanese Flounder by LoopMediated Isothermal Amplification (LAMP) Targeting the Internal Transcribed Spacer (ITS) Regions

J. Hikima, H. Yokoyama, M. Sakai, 2016 .

Generation of monoclonal antibodies specific for ORF68 of koi herpesvirus.

I. Hirono, T. Aoki, T. Takano, 2011, Comparative immunology, microbiology and infectious diseases.

ASC-deficiency impairs host defense against Aeromonas hydrophila infection in Japanese medaka, Oryzias latipes.

T. Aoki, H. Wang, J. Hikima, 2020, Fish & shellfish immunology.

Inflammatory immune response by lipopolysaccharide-responsive nucleotide binding oligomerization domain (NOD)-like receptors in the Japanese pufferfish (Takifugu rubripes).

J. Hikima, M. Sakai, T. Kono, 2016, Developmental and comparative immunology.

Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis.

J. Hikima, M. Sakai, T. Kono, 2015, Marine genomics.

Regulation of the immunoglobulin heavy chain locus expression at the phylogenetic level of a bony fish: transcription factor interaction with two variant octamer motifs.

G. Warr, N. Miller, Melanie R. Wilson, 2006, Gene.

Evolutional perspective and functional characteristics of interleukin-17 in teleosts.

J. Hikima, M. Sakai, T. Kono, 2022, Fish & shellfish immunology.

A defective interleukin-17 receptor A1 causes weight loss and intestinal metabolism-related gene downregulation in Japanese medaka, Oryzias latipes

Hiroshi Miyanishi, M. Kinoshita, J. Hikima, 2021, Scientific Reports.

Interleukin-17A/F1 from Japanese pufferfish (Takifugu rubripes) stimulates the immune response in head kidney and intestinal cells.

T. Aoki, H. Wang, J. Hikima, 2020, Fish & shellfish immunology.

Interleukin-17A/F1 Deficiency Reduces Antimicrobial Gene Expression and Contributes to Microbiome Alterations in Intestines of Japanese medaka (Oryzias latipes)

S. Watabe, Y. Saeki, D. Ikeda, 2020, Frontiers in Immunology.

Transcriptional regulation of type I interferon gene expression by interferon regulatory factor-3 in Japanese flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, Yoshiaki Suzuki, 2012, Developmental and comparative immunology.

Structure of the catfish IGH locus: analysis of the region including the single functional IGHM gene

G. Warr, G. Waldbieser, M. Wilson, 2006, Immunogenetics.

21 Genomics of Fish and Shellfi sh Microbial Pathogens

Mudjekeewis D. Santos, I. Hirono, T. Aoki, 2011 .

Genomics of fish and shellfish microbial pathogens.

Mudjekeewis D. Santos, I. Hirono, T. Aoki, 2011 .

Immunoglobulin genes and their transcriptional control in teleosts.

T. Aoki, J. Hikima, T. Jung, 2011, Developmental and comparative immunology.

Conservation and divergence of the Eμ3′ enhancer in the IGH locus of teleosts

G. Warr, L. Clem, N. Miller, 2006, Immunogenetics.

Molecular Characterization and Expression Analysis of Tumor Necrosis Factor Alpha-induced Protein 3 (TNFAIP3/A20) Gene from Japanese Pufferfish Takifugu rubripes

J. Hikima, M. Sakai, T. Kono, 2017 .

Interleukin-22 Deficiency Contributes to Dextran Sulfate Sodium-Induced Inflammation in Japanese Medaka, Oryzias latipes

Hiroshi Miyanishi, J. Hikima, M. Sakai, 2021, Frontiers in Immunology.

Evolution of vertebrate E protein transcription factors: comparative analysis of the E protein gene family in Takifugu rubripes and humans.

G. Warr, L. Clem, N. Miller, 2005, Physiological genomics.

Regulation of immunoglobulin gene transcription in a teleost fish: identification, expression and functional properties of E2A in the channel catfish

G. Warr, L. Clem, N. Miller, 2005, Immunogenetics.

Expression and biological activity of two types of interferon genes in medaka (Oryzias latipes).

C. Lo, T. Aoki, H. Wang, 2016, Fish & shellfish immunology.

Conservation of Structural and Functional Features in a Primordial CD80/86 Molecule from Rainbow Trout (Oncorhynchus mykiss), a Primitive Teleost Fish12

J. Hikima, J. Sunyer, S. Lapatra, 2009, The Journal of Immunology.

Nonconservation of TLR5 activation site in Edwardsiella tarda flagellin decreases expression of interleukin‐1&bgr; and NF‐&kgr;B genes in Japanese flounder, Paralichthys olivaceus

J. Hikima, M. Sakai, T. Kono, 2019, Fish & shellfish immunology.

Circadian clock components Bmal1 and Clock1 regulate tlr9 gene expression in the Japanese medaka (Oryzias latipes).

J. Hikima, M. Sakai, T. Kono, 2020, Fish & shellfish immunology.

Characterization and functional analysis of two PKR genes in fugu (Takifugu rubripes).

T. Aoki, M. Ohtani, J. Hikima, 2012, Fish & shellfish immunology.

Heat shock protein profiles on the protein and gene expression levels in olive flounder kidney infected with Streptococcus parauberis.

T. Aoki, J. Kwon, J. Hikima, 2013, Fish & shellfish immunology.

Complete Genome Sequence and Immunoproteomic Analyses of the Bacterial Fish Pathogen Streptococcus parauberis

I. Hirono, T. Aoki, J. Hikima, 2011, Journal of bacteriology.

Molecular Cloning and Sequence Analysis of Transferrin cDNA from Japanese Flounder Paralichthys olivaceus.

I. Hirono, T. Aoki, Yong-Ki Hong, 1997 .

Whole Genome Analyses of Marine Fish Pathogenic Isolate, Mycobacterium sp. 012931

I. Hirono, T. Aoki, H. Takeyama, 2014, Marine Biotechnology.

Comparative Genome Analysis of Fish and Human Isolates of Mycobacterium marinum

I. Hirono, T. Aoki, J. Hikima, 2013, Marine Biotechnology.

Molecular immunity in the interaction between fish and pathogen for DNA vaccine

I. Hirono, T. Aoki, J. Hikima, 2012 .

New Resources for Marine Genomics: Bacterial Artificial Chromosome Libraries for the Eastern and Pacific Oysters (Crassostrea virginica and C. gigas)

R. Wing, J. Tomkins, G. Warr, 2006, Marine Biotechnology.

Kidney proteome responses in the teleost fish Paralichthys olivaceus indicate a putative immune response against Streptococcus parauberis.

T. Aoki, J. Kwon, J. Hikima, 2012, Journal of proteomics.

Comparative genomics of transcription factors driving expression of the immunoglobulin heavy chain locus in teleost fish

G. Warr, N. Miller, Melanie R. Wilson, 2007 .

Characterization of an Oct1 orthologue in the channel catfish, Ictalurus punctatus: A negative regulator of immunoglobulin gene transcription?

G. Warr, N. Miller, Melanie R. Wilson, 2007, BMC molecular biology.

Function of E-protein dimers expressed in catfish lymphocytes.

G. Warr, N. Miller, Melanie R. Wilson, 2008, Molecular immunology.

Interaction between E-protein and Oct transcription factors in the function of the catfish IGH enhancer.

G. Warr, N. Miller, Melanie R. Wilson, 2008, Developmental and Comparative Immunology.

Variable domain antibodies specific for viral hemorrhagic septicemia virus (VHSV) selected from a randomized IgNAR phage display library.

I. Hirono, T. Aoki, H. Takeyama, 2013, Fish & shellfish immunology.

Circadian oscillation of TNF‐&agr; gene expression regulated by clock gene, BMAL1 and CLOCK1, in the Japanese medaka (Oryzias latipes)

J. Hikima, M. Sakai, T. Kono, 2019, International immunopharmacology.

Presence of two tumor necrosis factor (tnf)-α homologs on different chromosomes of zebrafish (Danio rerio) and medaka (Oryzias latipes).

J. Hikima, M. Sakai, T. Kono, 2014, Marine genomics.

Recombinant interferon-γ activates immune responses against Edwardsiella tarda infection in the olive flounder, Paralichthys olivaceus.

T. Aoki, M. Ohtani, J. Hikima, 2012, Fish & shellfish immunology.

Bacterial Classification of Fish-Pathogenic Mycobacterium Species by Multigene Phylogenetic Analyses and MALDI Biotyper Identification System

I. Hirono, T. Aoki, H. Takeyama, 2012, Marine Biotechnology.

Whole-Genome Sequence of Fish-Pathogenic Mycobacterium sp. Strain 012931, Isolated from Yellowtail (Seriola quinqueradiata)

I. Hirono, T. Aoki, H. Takeyama, 2013, Genome Announcements.

DNA vaccine-mediated innate immune response triggered by PRRs in teleosts

T. Aoki, T. Takano, J. Hikima, 2015, Fisheries Science.

LGP2 Expression is Enhanced by Interferon Regulatory Factor 3 in Olive Flounder, Paralichthys olivaceus

T. Aoki, H. Takeyama, M. Ohtani, 2012, PloS one.

Comparative Analysis of Plasmid DNAs from Two Strains of Photobacterium damselae subsp. piscicida Isolated from Japan and the United States

T. Aoki, A. Saeki, J. Hikima, 2020, Fish Pathology.

Whole-Genome Sequence of Photobacterium damselae subsp. piscicida Strain 91-197, Isolated from Hybrid Striped Bass (Morone sp.) in the United States

T. Aoki, H. Takeyama, J. Hawke, 2017, Genome Announcements.

Complete Genome Sequence of Photobacterium damselae subsp. piscicida Strain OT-51443 Isolated from Yellowtail (Seriola quinqueradiata) in Japan

T. Aoki, H. Takeyama, J. Hawke, 2017, Genome Announcements.

Identification of two interleukin 17 receptor C (IL-17RC) genes and their binding activities to three IL-17A/F ligands in the Japanese medaka, Oryzias latipes.

J. Hikima, M. Sakai, T. Kono, 2021, Developmental and comparative immunology.

Molecular characterization and expression of two interleukin-17 receptor A genes on different chromosomes in Japanese medaka, Oryzias latipes.

J. Hikima, M. Sakai, T. Kono, 2019, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Transcriptomic analysis of cultured kuruma shrimp primary lymphoid organ cells for identifying key cascades hindering sustainable culture

J. Hikima, M. Sakai, T. Kono, 2023, Fisheries Science.

Oct2 transcription factors in fish--a comparative genomic analysis.

G. Warr, L. Clem, N. Miller, 2006, Fish & shellfish immunology.

Construction of an Artificially Randomized IgNAR Phage Display Library: Screening of Variable Regions that Bind to Hen Egg White Lysozyme

I. Hirono, T. Aoki, M. Ohtani, 2013, Marine Biotechnology.

Deficiency of interleukin-17 receptor A1 induces microbiota disruption in the intestine of Japanese medaka, Oryzias latipes.

M. Kinoshita, J. Hikima, M. Sakai, 2021, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Kidney proteome responses in the teleost fish Paralichthys olivaceus indicate a putative immune response against Streptococcus parauberis.

T. Aoki, J. Kwon, J. Hikima, 2012, Journal of proteomics.

Molecular cloning and antiviral activity of IFN-β promoter stimulator-1 (IPS-1) gene in Japanese flounder, Paralichthys olivaceus.

I. Hirono, T. Aoki, M. Ohtani, 2010, Fish & shellfish immunology.

Evolutional Conservation of Molecular Structure and Antiviral Function of a Viral RNA Receptor, LGP2, in Japanese Flounder, Paralichthys olivaceus

I. Hirono, T. Aoki, M. Ohtani, 2010, The Journal of Immunology.

Complete Genome Sequence of Photobacterium damselae subsp. piscicida Strain OT-51443 Isolated from Yellowtail (Seriola quinqueradiata) in Japan

T. Aoki, H. Takeyama, J. Hawke, 2017, Genome Announcements.

Developmental and Comparative Immunology

T. Aoki, D. Steinhagen, J. Hikima, 2013 .

Comparative Genomic Characterization of Three Streptococcus parauberis Strains in Fish Pathogen, as Assessed by Wide-Genome Analyses

Yoji Nakamura, I. Hirono, T. Aoki, 2013, PloS one.