Shane R Thomas

发表

Neutrophil-mediated cardiac damage after acute myocardial infarction: Significance of defining a new target cell-type for developing cardioprotective drugs.

B. Chami, P. Witting, Mary El Kazzi, 2020, Antioxidants & redox signaling.

TRAIL protects against endothelial dysfunction in vivo and inhibits angiotensin‐II‐induced oxidative stress in vascular endothelial cells in vitro

B. Rayner, Shane R Thomas, M. Kavurma, 2018, Free radical biology & medicine.

Haematopoietic-expressed C/EBPβ: A novel transcriptional regulator of hepatic liver metabolism and macrophage foam cells during atherosclerosis?

Shane R Thomas, S. Thomas, 2016, Atherosclerosis.

Molecules in focus: indoleamine 2,3-dioxygenase.

N. King, Shane R Thomas, S. Thomas, 2007, The international journal of biochemistry & cell biology.

Suppression of the JNK Pathway by Induction of a Metabolic Stress Response Prevents Vascular Injury and Dysfunction

J. Keaney, T. Münzel, A. Daiber, 2008, Circulation.

Human Indoleamine 2,3-Dioxygenase Is a Catalyst of Physiological Heme Peroxidase Reactions

Andrew C. Terentis, P. Witting, E. Glaros, 2012, The Journal of Biological Chemistry.

Suppression of the JNK Pathway by Induction of a Metabolic Stress Response Prevents Vascular Injury and Dysfunction

J. Keaney, T. Münzel, A. Daiber, 2008 .

Hypochlorous Acid Impairs Endothelium-Derived Nitric Oxide Bioactivity Through a Superoxide-Dependent Mechanism

J. Keaney, R. Stocker, Shane R Thomas, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Activation of Endothelial Nitric-oxide Synthase by the p38 MAPK in Response to Black Tea Polyphenols*

J. Keaney, E. Schulz, J. Vita, 2004, Journal of Biological Chemistry.

Regulation of the nitric oxide oxidase activity of myeloperoxidase by pharmacological agents

Jonathan C. Morris, Shane R Thomas, Martin D. Rees, 2017, Biochemical pharmacology.

Mitochondrial Function Is Required for Hydrogen Peroxide-induced Growth Factor Receptor Transactivation and Downstream Signaling*

J. Keaney, Kai Chen, M. Murphy, 2004, Journal of Biological Chemistry.

Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans.

J. Neuzil, J. Štursa, Susan Hall, 2014, Free radical biology & medicine.

Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice

H. Harith, L. Adams, Shane R Thomas, 2017, Scientific Reports.

Post-translational Regulation of Human Indoleamine 2,3-Dioxygenase Activity by Nitric Oxide*

P. A. Lay, Andrew C. Terentis, R. Stocker, 2007, Journal of Biological Chemistry.

Processes Involved in the Site-Specific Effect of Probucol on Atherosclerosis in Apolipoprotein E Gene Knockout Mice

Trevor A. Mori, R. Stocker, K. Croft, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Tumor Necrosis Factor–Related Apoptosis‐Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia‐Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide–Dependent Mechanisms

L. Prado-Lourenço, T. Griffith, Shane R Thomas, 2015, Journal of the American Heart Association.

Periodontitis induces endothelial dysfunction in mice

G. Cooney, Boris Guennewig, G. Sutherland, 2021, Scientific Reports.

Dietary Cosupplementation With Vitamin E and Coenzyme Q10 Inhibits Atherosclerosis in Apolipoprotein E Gene Knockout Mice

Trevor A. Mori, R. Stocker, K. Croft, 2001, Arteriosclerosis, thrombosis, and vascular biology.

S-Nitrosylated S 100 A 8 : Novel Anti-Inflammatory Properties 1

D. Richardson, M. Raftery, C. Geczy, 2008 .

S-Nitrosylated S100A8: Novel Anti-Inflammatory Properties1

D. Richardson, M. Raftery, C. Geczy, 2008, The Journal of Immunology.

Apolipoprotein A-I Increases Insulin Secretion and Production From Pancreatic &bgr;-Cells via a G-Protein-cAMP-PKA-FoxO1–Dependent Mechanism

P. Barter, Jérémie Rossy, K. Rye, 2014, Arteriosclerosis, thrombosis, and vascular biology.

The pleiotropic effects of high-density lipoproteins and apolipoprotein A-I.

K. Rye, Shane R Thomas, Yunjia Zhang, 2022, Best practice & research. Clinical endocrinology & metabolism.

Flavivirus infection induces indoleamine 2,3‐dioxygenase in human monocyte‐derived macrophages via tumor necrosis factor and NF‐κB

R. Stocker, N. King, Shane R Thomas, 2012, Journal of leukocyte biology.

Inhibition of Myeloperoxidase-Mediated Endothelial Dysfunction by Nitroxides

Jonathan C. Morris, Shane R Thomas, Martin D. Rees, 2015 .

Sustained expression of heme oxygenase-1 alters iron homeostasis in nonerythroid cells.

D. Richardson, B. Halliwell, R. Stocker, 2012, Free radical biology & medicine.

Phenazine virulence factor binding to extracellular DNA is important for Pseudomonas aeruginosa biofilm formation

J. Gooding, J. Gooding, M. Manefield, 2015, Scientific Reports.

Design and Rationale for the Endothelin-1 Receptor Antagonism in the Prevention of Microvascular Injury in Patients with non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention (ENDORA-PCI) Trial

S. Ooi, Shane R Thomas, E. Russell, 2016, Cardiovascular Drugs and Therapy.

Heparanase: A Novel Therapeutic Target for the Treatment of Atherosclerosis

Enoch Chan, M. Hulett, Shane R Thomas, 2022, Cells.

Effect of atorvastatin on endothelium-dependent vasodilation in patients with coronary artery disease.

J. Keaney, S. Duffy, N. Gokce, 2003, The American journal of cardiology.

Cytochrome b5, Not Superoxide Anion Radical, Is a Major Reductant of Indoleamine 2,3-Dioxygenase in Human Cells*

R. Stocker, N. Hunt, Shane R Thomas, 2008, Journal of Biological Chemistry.

Mechanism and regulation of peroxidase-catalyzed nitric oxide consumption in physiological fluids: critical protective actions of ascorbate and thiocyanate.

A. Kettle, Shane R Thomas, Martin D. Rees, 2014, Free radical biology & medicine.

Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

I. Campbell, D. Getts, N. King, 2012, Journal of Neuroinflammation.

Corrigendum: Kynurenine is an endothelium-derived relaxing factor produced during inflammation

J. Stasch, J. Keaney, D. Celermajer, 2010, Nature Medicine.

Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1

C. Sobey, E. Glaros, Shane R Thomas, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr

L. Hesson, J. Wong, Yizhou Huang, 2016, Molecular and Cellular Biology.

Human Indoleamine 2,3-Dioxygenase 1 Is an Efficient Mammalian Nitrite Reductase.

Andrew C. Terentis, Yuanqing Ma, P. Witting, 2018, Biochemistry.

Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1

C. Sobey, E. Glaros, Shane R Thomas, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Urate as a Physiological Substrate for Myeloperoxidase

A. Kettle, D. T. Harwood, Shane R Thomas, 2011, The Journal of Biological Chemistry.

Oxidative stress and endothelial nitric oxide bioactivity.

J. Keaney, Kai Chen, Shane R Thomas, 2003, Antioxidants & redox signaling.

Role of indoleamine 2,3-dioxygenase in health and disease.

Andrew C. Terentis, Shane R Thomas, N. King, 2015, Clinical science.

Hydrogen peroxide restrains endothelium-derived nitric oxide bioactivity -- role for iron-dependent oxidative stress.

J. Keaney, E. Schulz, Shane R Thomas, 2006, Free radical biology & medicine.

The Heme Environment of Recombinant Human Indoleamine 2,3-Dioxygenase

Andrew C. Terentis, R. Truscott, R. Stocker, 2002, The Journal of Biological Chemistry.

Myeloperoxidase: A versatile mediator of endothelial dysfunction and therapeutic target during cardiovascular disease.

Enoch Chan, Shane R Thomas, Martin D. Rees, 2020, Pharmacology & therapeutics.

Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.

P. Witting, Shane R Thomas, G. Drummond, 2008, Antioxidants & redox signaling.

Antioxidants Inhibit Indoleamine 2,3-Dioxygenase in IFN-γ-Activated Human Macrophages: Posttranslational Regulation by Pyrrolidine Dithiocarbamate1

D. Richardson, R. Stocker, N. Hunt, 2001, The Journal of Immunology.

Hydrogen Peroxide Activates Endothelial Nitric-oxide Synthase through Coordinated Phosphorylation and Dephosphorylation via a Phosphoinositide 3-Kinase-dependent Signaling Pathway*

J. Keaney, Kai Chen, Shane R Thomas, 2002, The Journal of Biological Chemistry.

L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells.

J. Loscalzo, J. Keaney, D. Pimentel, 2004, Free radical biology & medicine.

HDL maturation and remodelling.

K. Rye, K. Ong, Shane R Thomas, 2022, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Kynurenine is an endothelium-derived relaxing factor produced during inflammation

J. Stasch, J. Keaney, D. Celermajer, 2010, Nature Medicine.

Kynurenine is a novel endothelium-derived vascular relaxing factor produced during inflammation

J. Stasch, J. Keaney, C. Sobey, 2009, BMC Pharmacology.

Hypoxia regulates the production and activity of glucose transporter‐1 and indoleamine 2,3‐dioxygenase in monocyte‐derived endothelial‐like cells: possible relevance to infantile haemangioma pathogenesis

P. Hogg, W. Jessup, Shane R Thomas, 2011, The British journal of dermatology.

Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells

D. Owen, Shane R Thomas, E. Malle, 2012, Free radical biology & medicine.

Beyond LDL oxidation: ROS in vascular signal transduction.

J. Keaney, Kai Chen, Shane R Thomas, 2003, Free radical biology & medicine.

Regulation of Angiogenesis by Glycogen Synthase Kinase-3β*

M. Birnbaum, J. Keaney, K. Walsh, 2002, The Journal of Biological Chemistry.

MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation

D. Beck, J. Wong, Yizhou Huang, 2016, Leukemia.

Vitamin E Oxidation in Human Atherosclerotic Lesions

Andrew C. Terentis, D. Liebler, R. Stocker, 2002, Circulation research.

Mechanisms of Antioxidant Action of Ubiquinol-10 for Low-Density Lipoprotein

R. Stocker, Shane R Thomas, S. Thomas, 2000 .

Endothelial-Transcytosed Myeloperoxidase Activates Endothelial Nitric Oxide Synthase via a Phospholipase C-Dependent Calcium Signaling Pathway.

J. Keaney, Enoch Chan, C. Geczy, 2021, Free radical biology & medicine.

Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

B. Göttgens, V. Kouskoff, J. Pimanda, 2015, Biology Open.

Measurements of redox control of nitric oxide bioavailability.

J. Keaney, Shane R Thomas, A. Huang, 2002, Methods in enzymology.

Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.

P. Witting, Shane R Thomas, G. Drummond, 2008, Antioxidants & redox signaling.

Kynurenine is an endothelium-derived relaxing factor produced during inflammation

J. Stasch, J. Keaney, D. Celermajer, 2010, Nature Medicine.

Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

I. Campbell, D. Getts, N. King, 2012, Journal of Neuroinflammation.

Identification of Native and Posttranslationally Modified HLA‐B*57:01‐Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

Sri H. Ramarathinam, S. Alcântara, R. Center, 2018, Proteomics.

Impact of Reperfusion on Temporal Immune Cell Dynamics After Myocardial Infarction.

K. Rye, B. Cochran, Shane R Thomas, 2023, Journal of the American Heart Association.

Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells

D. Owen, Shane R Thomas, E. Malle, 2012, Free radical biology & medicine.

Apolipoprotein A-I Increases Insulin Secretion and Production From Pancreatic &bgr;-Cells via a G-Protein-cAMP-PKA-FoxO1–Dependent Mechanism

P. Barter, Jérémie Rossy, K. Rye, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells

K. Gaus, C. Rentero, C. Enrich, 2016, PloS one.

Using cell-substrate impedance and live cell imaging to measure real-time changes in cellular adhesion and de-adhesion induced by matrix modification.

Shane R Thomas, Martin D. Rees, 2015, Journal of visualized experiments : JoVE.