B. Liang

发表

CD13 is essential for inflammatory trafficking and infarct healing following permanent coronary artery occlusion in mice

M. Ghosh, Si-Yuan Zhou, J. Subramani, 2013, Cardiovascular research.

Constitutive Activation of A3 Adenosine Receptors by Site-Directed Mutagenesis

K. Jacobson, Zhang-Guo Gao, D. Barak, 2001 .

Engineering of A3 adenosine and P2Y nucleotide receptors and their ligands

K. Jacobson, Zhang-Guo Gao, D. Barak, 2003, Drug development research.

The clinical impact of circulating caspase-3 p17 level: a potential new biomarker for myocardial injury and cardiovascular disease.

A. Jaffe, B. Liang, Kanwar P Singh, 2011, Future cardiology.

Nucleotide receptor P2x4 : Abstract : UCSD-Nature Molecule Pages

G. Burnstock, B. Liang, X. Bo, 2008 .

Elevated Vascular Endothelial Growth Factor Receptor-2 Abundance Contributes to Increased Angiogenesis in Vascular Endothelial Growth Factor Receptor-1–Deficient Mice

G. Fong, Chunxia G. Cronin, B. Liang, 2012, Circulation.

Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury.

K. Jacobson, Dan Wu, B. Liang, 2007, American journal of physiology. Heart and circulatory physiology.

Methods to Protect from Skeletal Cardiovascular Insufficiency: Improving Soldier Performance in Adverse Environments

W. White, B. Liang, G. Mansoor, 2006 .

Serotonin mechanisms in heart valve disease I: serotonin-induced up-regulation of transforming growth factor-beta1 via G-protein signal transduction in aortic valve interstitial cells.

R. Levy, N. Narula, R. Savani, 2002, The American journal of pathology.

Protection of cardiac myocytes via δ1-opioid receptors, protein kinase C, and mitochondrial KATP channels

G. Gross, H. Nagase, B. Liang, 2001 .

5'-Phosphate and 5'-phosphonate ester derivatives of (N)-methanocarba adenosine with in vivo cardioprotective activity.

K. Jacobson, Chunxia G. Cronin, Jian-bing Shen, 2013, Journal of medicinal chemistry.

Endothelin enhances the contractile responsiveness of adult rat ventricular myocytes to calcium by a pertussis toxin-sensitive pathway.

B. Krämer, B. Liang, R. Kelly, 1990, The Journal of clinical investigation.

A beneficial role of cardiac P2X4 receptors in heart failure: rescue of the calsequestrin overexpression model of cardiomyopathy.

W. Barry, B. Liang, L. Jones, 2004, American journal of physiology. Heart and circulatory physiology.

Adenosine A(3) receptor stimulation induces protection of skeletal muscle from eccentric exercise-mediated injury.

K. Campbell, Ruibo Wang, B. Liang, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Role of direct RhoA‐phospholipase D interaction in mediating adenosine‐induced protection from cardiac ischemia

K. Jacobson, B. Joshi, B. Liang, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adenosine A1 and A3 receptors: Distinct cardioprotection

K. Jacobson, B. Liang, Douglas R. Stewart, 2001 .

A Novel Pharmacological Approach to Treating Cardiac Ischemia

K. Jacobson, B. Liang, L. Chang, 2000, The Journal of Biological Chemistry.

Distinct cardioprotective effects of adenosine mediated by differential coupling of receptor subtypes to phospholipases C and D

K. Jacobson, B. Liang, L. Young, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Distinct cardioprotective effects of adenosine mediated by differential coupling of receptor subtypes to phospholipases C and D

K. Jacobson, B. Liang, L. Young, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adenosine Receptor Subtypes and Cardioprotection in Cardiac Myocyte and Transgenic Models

J. Headrick, B. Liang, G. Matherne, 1998 .

Adenosine receptor subtypes and cardioprotection

K. Jacobson, M. Dichter, K. Wilcox, 1998, Drug development research.

Protein kinase C-dependent activation of KATP channel enhances adenosine-induced cardioprotection.

B. Liang, 1998, The Biochemical journal.

Cardiac myocytes rendered ischemia resistant by expressing the human adenosine A1 or A3 receptor

P. Schofield, K. Jacobson, B. Liang, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Direct preconditioning of cultured chick ventricular myocytes. Novel functions of cardiac adenosine A2a and A3 receptors.

K. Jacobson, J. Strickler, B. Liang, 1996, The Journal of clinical investigation.

Atrium- and ventricle-specific expression of adenosine receptor subtypes: Functional and molecular evidence for a stimulatory adenosine receptor subtype on ventricular myocytes

B. Liang, 1992 .

Expression and pharmacological characterization of a stimulatory subtype of adenosine receptor in fetal chick ventricular myocytes.

B. Liang, H. Kong, D. Xu, 1992, Circulation research.

P2X4 receptor–eNOS signaling pathway in cardiac myocytes as a novel protective mechanism in heart failure

K. Jacobson, K. Dodge-Kafka, Jian-bing Shen, 2014, Computational and structural biotechnology journal.

eNOS signaling pathway in cardiac myocytes as a novel 3 protective mechanism in heart failure

K. Jacobson, K. Dodge-Kafka, Jian-bing Shen, 2014 .

Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells.

R. Levy, P. Mcgonigle, B. Liang, 2002, The American journal of pathology.

A novel contractile phenotype with cardiac transgenic expression of the human P2X4 receptor

W. Barry, B. Liang, B. Hu, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Characterization of a stimulatory adenosine A2a receptor in adult rat ventricular myocyte.

B. Liang, B. Stein, H. Xu, 1996, The American journal of physiology.

Phospholipase Cβ2 Promotes Vascular Endothelial Growth Factor Induced Vascular Permeability

Luke H. Hoeppner, K. Phoenix, K. Claffey, 2022, bioRxiv.

Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation.

K. Jacobson, L. Mamedova, P. Besada, 2008, Pharmacological research.

Constitutive activation of A(3) adenosine receptors by site-directed mutagenesis.

K. Jacobson, D. Barak, B. Liang, 2001, Biochemical and biophysical research communications.

Usefulness of Circulating Caspase-3 p17 and Caspase-1 p20 Peptides and Cardiac Troponin 1 During Cardioplegia to Gauge Myocardial Preservation.

S. Lahey, B. Liang, Daniel Fusco, 2019, The American journal of cardiology.

Direct preconditioning of cardiac myocytes via opioid receptors and KATP channels.

G. Gross, B. Liang, 1999, Circulation research.

A New Cyclic AMP-independent, Gs-mediated Stimulatory Mechanism via the Adenosine A2a Receptor in the Intact Cardiac Cell*

J. Morley, B. Liang, James F Morley, 1996, The Journal of Biological Chemistry.

Adenosine A3 Receptors in Muscle Protection

K. Jacobson, B. Liang, M. Urso, 2010 .

Utilization of Military-Relevant Muscle Injury Models to Identify Pharmacological Treatment Strategies

T. Walters, B. R. Barnes, Eric R. Szelenyi, 2008 .

Beta-adrenergic receptor-G protein-adenylate cyclase complex in experimental canine congestive heart failure produced by rapid ventricular pacing.

P. Molinoff, J. Wilson, B. Liang, 1991, Circulation research.

Adenosine receptors and cardiovascular function.

B. Liang, 1992, Trends in cardiovascular medicine.

Molecular mechanism of contractile dysfunction in cardiac allograft rejection.

B. Liang, V. Disesa, A. K. Hanna, 1992, The Journal of surgical research.

Adenosine A3 receptor stimulation reduces muscle injury following physical trauma and is associated with alterations in the MMP/TIMP response.

Ruibo Wang, B. Liang, M. Urso, 2012, Journal of applied physiology.

Protein and a1-Adrenergic Receptors

W. Colucci, B. Liang, L. Sen, 2005 .

Enhanced alpha 1-adrenergic responsiveness in cardiomyopathic hamster cardiac myocytes. Relation to the expression of pertussis toxin-sensitive G protein and alpha 1-adrenergic receptors.

W. Colucci, B. Liang, T. Smith, 1990, Circulation research.

Development of muscarinic cholinergic inhibition of adenylate cyclase in embryonic chick heart. Its relationship to changes in the inhibitory guanine nucleotide regulatory protein.

E. Neer, J. Galper, B. Liang, 1986, The Journal of biological chemistry.

PLCβ2 Promotes VEGF-Induced Vascular Permeability

Luke H. Hoeppner, K. Phoenix, K. Claffey, 2022 .

Elevated VEGF Receptor-2 Abundance Contributes to Increased Angiogenesis in VEGF Receptor-1 Deficient Mice

G. Fong, Chunxia G. Cronin, B. Liang, 2012 .

Serum caspase-3 p17 fragment is elevated in patients with ST-segment elevation myocardial infarction: a novel observation.

A. Jaffe, M. Agosto, B. Liang, 2011, Journal of the American College of Cardiology.

Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis.

Ping Huang, G. Du, M. Frohman, 2003, Molecular biology of the cell.

Beta adrenergic receptor subtypes in the atria: evidence for close coupling of beta-1 and beta-2 adrenergic receptors to adenylate cyclase.

P. Molinoff, B. Liang, 1986, The Journal of pharmacology and experimental therapeutics.

Novel Protective Role of Endogenous Cardiac Myocyte P2X4 Receptors in Heart Failure

K. Jacobson, K. Dodge-Kafka, Jian-bing Shen, 2014, Circulation. Heart failure.

Defining late onset occult asymptomatic cardiotoxicity in childhood cancer survivors exposed to anthracycline therapy: a cardiac magnetic resonance imaging study

E. Gillan, M. Taylor, J. Stainsby, 2013, Journal of Cardiovascular Magnetic Resonance.

Deletion of the P2X4 receptor is neuroprotective acutely, but induces a depressive phenotype during recovery from ischemic stroke

L. McCullough, V. Venna, J. Hudobenko, 2017, Brain, Behavior, and Immunity.

Reversible contractile dysfunction in reversible experimental cardiac allograft rejection: alterations in the beta-receptor-stimulated adenylylcyclase pathway.

B. Liang, V. Disesa, A. K. Hanna, 1993, The Journal of surgical research.

Neoceptors: reengineering GPCRs to recognize tailored ligands.

K. Jacobson, Zhang-Guo Gao, B. Liang, 2007, Trends in pharmacological sciences.

Protein kinase C-mediated preconditioning of cardiac myocytes: role of adenosine receptor and KATP channel.

B. Liang, 1997, The American journal of physiology.

Direct preconditioning of cardiac ventricular myocytes via adenosine A1 receptor and KATP channel.

B. Liang, 1996, The American journal of physiology.

Nucleotide receptor P2x4

G. Burnstock, B. Liang, X. Bo, 2006 .

A novel phospholipase Cand cAMP-independent positive inotropic mechanism via a P 2 purinoceptor

B. Liang, E. Podrasky, X. David, 1997 .

TRPM7-Mediated Ca2+ Signals Confer Fibrogenesis in Human Atrial Fibrillation

Jia Xie, Lixia Yue, Jianyang Du, 2010, Circulation research.

Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists.

K. Jacobson, Philippe van Rompaey, S. van Calenbergh, 2006, Journal of medicinal chemistry.

Structure-Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2H-naphtho[1,2-b][1,4]diazepine-2,4(3H)-diones as P2X4 Receptor Antagonists.

K. Jacobson, B. Liang, Rajkumar Verma, 2022, Journal of medicinal chemistry.

Cardiovascular Biology of Purines

G. Burnstock, J. Linden, B. Liang, 1998, Developments in Cardiovascular Medicine.

Pharmacological and therapeutic effects of A3 adenosine receptor agonists.

K. Jacobson, P. Fishman, B. Liang, 2012, Drug discovery today.

Differential sensitivity of αo and αi to ADP-ribosylation by pertussis toxin in the intact cultured embryonic chick ventricular myocyte: Relationship to the role of g proteins in the coupling of muscarinic cholinergic receptors to inhibition of adenylate cyclase activity

J. Galper, B. Liang, 1988 .

Studies on Dihydropteridine Reductase Activity in Pheochromocytoma Cells

R. Perlman, B. Liang, B. A. Perelle, 1981, Journal of neurochemistry.

Semi-rational design of (north)-methanocarba nucleosides as dual acting A(1) and A(3) adenosine receptor agonists: novel prototypes for cardioprotection.

K. Jacobson, Zhang-Guo Gao, B. Joshi, 2005, Journal of medicinal chemistry.

Minimizing Skeletal Muscle Injury to Ischemia/Reperfusion with Adenosine A3 Receptor Agonists: Role of Matrix Metalloproteases

B. Liang, M. Urso, E. Zambraski, 2009 .

P2 purinergic receptor activation enhances cardiac contractility in isolated rat and mouse hearts.

Q. Mei, B. Liang, Qi-Bing Mei, 2001, American journal of physiology. Heart and circulatory physiology.

100 Years of evolving gene-disease complexities and scientific debutants

Zeeshan Ahmed, Saman Zeeshan, Ruoyun Xiong, 2019, Briefings Bioinform..

Debutant iOS app and gene-disease complexities in clinical genomics and precision medicine

Zeeshan Ahmed, Saman Zeeshan, Ruoyun Xiong, 2019, Clinical and Translational Medicine.

Structure-activity relationship of (N)-Methanocarba phosphonate analogues of 5'-AMP as cardioprotective agents acting through a cardiac P2X receptor.

K. Jacobson, Si-Yuan Zhou, B. Joshi, 2010, Journal of medicinal chemistry.

Regulation of the endothelial cell urokinase-type plasminogen activator receptor. Evidence for cyclic AMP-dependent and protein kinase C-dependent pathways.

J. Hoxie, D. Cines, K. Karikó, 1993, Circulation research.

Use of integrated imaging and serum biomarker profiles to identify subclinical dysfunction in pediatric cancer patients treated with anthracyclines

C. Zeiss, D. Gatti, J. Lee, 2018, Cardio-Oncology.

PAS-SNP: iOS App with GWAS SNP-Disease Database for Personalized Genomics Research: PAS-SNP for GWAS SNP-Disease

Zeeshan Ahmed, Saman Zeeshan, Bruce T. Liang, 2019, 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

A physiological role of the adenosine A3 receptor: sustained cardioprotection.

K. Jacobson, B. Liang, Kenneth A. Jacobson, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Stimulatory Subtpe of Adenosine Receptor in Fetal Chick Ventricular Myocytes

B. Liang, H. Kong, 2005 .

Adenosine A2a and A2b receptors in cultured fetal chick heart cells. High- and low-affinity coupling to stimulation of myocyte contractility and cAMP accumulation.

B. Liang, B. Haltiwanger, 1995, Circulation research.

Ischemic Conditioning and Atrial Fibrillation: Hope for a NewTherapy?

B. Liang, Christopher C. Pickett, Heiko Schmitt, 2013, Journal of atrial fibrillation.

TRPM 7-mediated Ca 2 + Signals Confer Fibrogenesis in Human Atrial Fibrillation

Lixia, Jianyang Du, B. Liang, 2019 .

A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia.

K. Jacobson, B. Liang, J. Jiang, 1997, The American journal of physiology.

Occult Cardiotoxicity in Childhood Cancer Survivors Exposed to Anthracycline Therapy

S. Raman, E. Gillan, J. Stainsby, 2013, Circulation. Cardiovascular imaging.

Characterization and mechanism of P2X receptor-mediated increase in cardiac myocyte contractility.

A. Pappano, Jian-bing Shen, B. Liang, 2007, American journal of physiology. Heart and circulatory physiology.

Neuroprotective and neuro-rehabilitative effects of acute purinergic receptor P2X4 (P2X4R) blockade after ischemic stroke

K. Jacobson, V. Scranton, Chunxia G. Cronin, 2020, Experimental Neurology.

Protection of cardiac myocytes via delta(1)-opioid receptors, protein kinase C, and mitochondrial K(ATP) channels.

G. Gross, H. Nagase, B. Liang, 2001, American journal of physiology. Heart and circulatory physiology.

cPLA2 is protective against COX inhibitor-induced intestinal damage.

Krishna Kadaveru, G. Belinsky, R. Murphy, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

A novel phospholipase C- and cAMP-independent positive inotropic mechanism via a P2 purinoceptor.

B. Liang, D. Xu, E. Podrasky, 1997, American journal of physiology. Heart and circulatory physiology.

Reduced in vivo toxicity of doxorubicin by encapsulation in cholesterol-containing self-assembled nanoparticles.

Ming-Hui Chen, R. Kasi, J. Manautou, 2016, Pharmacological research.

Ca2+ Signaling in Cardiac Fibroblasts and Fibrosis-Associated Heart Diseases

Albert S. Yu, Lixia Yue, L. Runnels, 2019, Journal of cardiovascular development and disease.

A novel cardioprotective role of RhoA: new signaling mechanism for adenosine.

G. Bokoch, B. Liang, J. E. Lee, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Pharmacological and Therapeutic Effects of A 3 Adenosine Receptor ( A 3 AR ) Agonists

K. Jacobson, P. Fishman, B. Liang, 2017 .

PAS-Code: iOS App with Mobile Access to the International Classified Disease and Drug Databases for Health Informatics & Precision Medicine: PAS-Code with ICD and NDC

Zeeshan Ahmed, Saman Zeeshan, Bruce T. Liang, 2019, 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.

K. Jacobson, S. van Calenbergh, Zhang-Guo Gao, 2001, Journal of medicinal chemistry.

Beta 2-adrenergic receptors contribute to catecholamine-stimulated shortening of action potential duration in dog atrial muscle.

P. Molinoff, B. Liang, L. H. Frame, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Additive effects of late preconditioning produced by monophosphoryl lipid A and the early preconditioning mediated by adenosine receptors and KATP channel.

K. Jacobson, B. Liang, G. T. Elliott, 1999, Circulation.

P2X purinergic receptor-mediated ionic current in cardiac myocytes of calsequestrin model of cardiomyopathy: implications for the treatment of heart failure.

K. Jacobson, D. Harrison, B. Joshi, 2007, American journal of physiology. Heart and circulatory physiology.

P 2 X purinergic receptor-mediated ionic current in cardiac myocytes of calsequestrin model of cardiomyopathy : implications for the treatment of heart failure

K. Jacobson, D. Harrison, B. Joshi, 2007 .

P2X4 Receptor Is a Glycosylated Cardiac Receptor Mediating a Positive Inotropic Response to ATP*

B. Liang, F. Soto, Bing Hu, 2002, The Journal of Biological Chemistry.

Differential desensitization of A1 adenosine receptor-mediated inhibition of cardiac myocyte contractility and adenylate cyclase activity. Relation to the regulation of receptor affinity and density.

L. Donovan, B. Liang, 1990, Circulation Research.

Treatment of Heart Failure by a Methanocarba Derivative of Adenosine Monophosphate: Implication for a Role of Cardiac Purinergic P2X Receptors

K. Jacobson, F. Recchia, T. Hintze, 2010, Journal of Pharmacology and Experimental Therapeutics.

Treatment of Heart Failure by a Methanocarba Derivative of Adenosine Monophosphate : Implication for a Role of Cardiac Purinergic P 2 X Receptors

K. Jacobson, F. Recchia, T. Hintze, 2010 .

Characterization of the adenosine receptor in cultured embryonic chick atrial myocytes: coupling to modulation of contractility and adenylate cyclase activity and identification by direct radioligand binding.

B. Liang, 1989, The Journal of pharmacology and experimental therapeutics.

Cardiac P2X purinergic receptors as a new pathway for increasing Na⁺ entry in cardiac myocytes.

A. Pappano, Jian-bing Shen, B. Liang, 2014, American journal of physiology. Heart and circulatory physiology.

Cardiac P2X(4) receptors: targets in ischemia and heart failure?

B. Liang, Ronghua Yang, 2012, Circulation research.

Targets in Ischemia and Heart Failure?

B. Liang, Ronghua Yang, 2012 .

Tyrosine 3-monooxygenase regulates catecholamine synthesis in pheochromocytoma cells.

R. Perlman, B. Liang, B. A. Perelle, 1980, Journal of Biological Chemistry.

Dsp rul: a spontaneous mouse mutation in desmoplakin as a model of Carvajal-Huerta syndrome.

L. Reinholdt, J. Sundberg, P. Schofield, 2015, Experimental and molecular pathology.

Reversal of cardiac myocyte dysfunction as a unique mechanism of rescue by P2X4 receptors in cardiomyopathy.

A. Pappano, M. Agosto, Jian-bing Shen, 2009, American journal of physiology. Heart and circulatory physiology.

cardiomyopathy mechanism of rescue by P 2 X 4 receptors in Reversal of cardiac myocyte dysfunction as a unique

A. Pappano, M. Agosto, Jian-bing Shen, 2009 .

Role of P2X purinergic receptors in the rescue of ischemic heart failure.

K. Jacobson, Si-Yuan Zhou, A. Pappano, 2008, American journal of physiology. Heart and circulatory physiology.

Role of P 2 X purinergic receptors in the rescue of ischemic heart failure

K. Jacobson, Si-Yuan Zhou, A. Pappano, 2008 .

, Kenneth A . heart failure Role of P 2 X purinergic receptors in the rescue of ischemic

K. Jacobson, Si-Yuan Zhou, A. Pappano, 2008 .

Prevention and rescue of cardiac dysfunction by methanocarba adenosine monophosphonate derivatives

K. Jacobson, Chunxia G. Cronin, Jian-bing Shen, 2020, Purinergic Signalling.

Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y14 Receptor Antagonists.

K. Jacobson, Zhang-Guo Gao, Sylvie Breton, 2023, Journal of medicinal chemistry.

Extracellular ATP‐stimulated current in wild‐type and P2X4 receptor transgenic mouse ventricular myocytes: implications for a cardiac physiologic role of P2X4 receptors

A. Pappano, Jian-bing Shen, B. Liang, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cloning, functional characterization and developmental expression of a P2X receptor from chick embryo.

A. Ruppelt, B. Liang, F. Soto, 1999, Progress in brain research.

Digital holographic deep learning of red blood cells for field-portable, rapid COVID-19 screening.

B. Javidi, T. O’Connor, Jian-bing Shen, 2021, Optics letters.

RNA-seq driven expression and enrichment analysis to investigate CVD genes with associated phenotypes among high-risk heart failure patients

Zeeshan Ahmed, Saman Zeeshan, B. Liang, 2021, Human Genomics.

Transcriptomic analysis reveals novel age-independent immunomodulatory proteins as a mode of cerebroprotection in P2X4R KO mice after ischemic stroke

B. Liang, Rajkumar Verma, Daylin Gamiotea-Turro, 2023, Research square.