Ying Shao

发表

ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes

Xianwei Wang, Xiaofeng Yang, J. Saredy, 2020, Redox biology.

Low-Intensity Ultrasound-Induced Anti-inflammatory Effects Are Mediated by Several New Mechanisms Including Gene Induction, Immunosuppressor Cell Promotion, and Enhancement of Exosome Biogenesis and Docking

Xiaofeng Yang, William Y. Yang, Yu Sun, 2017, Front. Physiol..

Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis

Yan Zhou, Daohai Yu, K. Bayless, 2020, Frontiers in Immunology.

Early Hyperlipidemia Promotes Endothelial Activation via a Caspase-1-Sirtuin 1 Pathway

Hong Wang, D. Tilley, Ying-Xuan Yin, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Mitochondrial Proton Leak Plays a Critical Role in Pathogenesis of Cardiovascular Diseases.

Hong Wang, Jiali Cheng, Xiaofeng Yang, 2017, Advances in experimental medicine and biology.

Experimental Data-Mining Analyses Reveal New Roles of Low-Intensity Ultrasound in Differentiating Cell Death Regulatome in Cancer and Non-cancer Cells via Potential Modulation of Chromatin Long-Range Interactions

Daohai Yu, Xiaofeng Yang, William Y. Yang, 2019, Front. Oncol..

Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study

Hong Wang, Jiali Cheng, Xiaoshu Cheng, 2016, Journal of Hematology & Oncology.

GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg

Hong Wang, Xiaofeng Yang, William Y. Yang, 2018, Front. Immunol..

DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses—Inflammations and Cancers Can Have High Genomic Risks

Joon-Young Park, Xiaofeng Yang, Lijian Shao, 2018, Front. Physiol..

Chronic Exposure to the Combination of Cigarette Smoke and Morphine Decreases CD4+ Regulatory T Cell Numbers by Reprogramming the Treg Cell Transcriptome

G. Criner, Xiaofeng Yang, Hong Wang, 2022, Frontiers in Immunology.

Interleukin-17A Promotes Aortic Endothelial Cell Activation via Transcriptionally and Post-translationally Activating p38 Mitogen-activated Protein Kinase (MAPK) Pathway*

Hong Wang, Y. Iwakura, Xiaofeng Yang, 2016, The Journal of Biological Chemistry.

Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

D. Praticò, Xiaofeng Yang, Jianxin Sun, 2021, Frontiers in Cardiovascular Medicine.

Co-signaling receptors regulate T-cell plasticity and immune tolerance.

Xiaofeng Yang, William Y. Yang, Haitao Shen, 2019, Frontiers in bioscience.

Cigarette smoke modulates inflammation and immunity via ROS-regulated trained immunity and trained tolerance mechanisms.

Xiaofeng Yang, Hong Wang, Ying Shao, 2022, Antioxidants & redox signaling.

Cigarette Smoke and Morphine Promote Treg Plasticity to Th17 via Enhancing Trained Immunity

Xiaofeng Yang, Hong Wang, Yifan Lu, 2022, Cells.

Uremic toxins are conditional danger‐ or homeostasis‐ associated molecular patterns, which are highly selective increase rather than purely passive accumulation, in chronic kidney disease and coronary arteria disease

Hong Wang, Rongshan Li, Xiaofeng Yang, 2018, Frontiers in bioscience.

Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells

Xiaofeng Yang, Xinyuan Li, Pu Fang, 2019, Redox biology.

Vascular Endothelial Cells and Innate Immunity.

Xiaofeng Yang, J. Saredy, William Y. Yang, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Editorial: Endothelial cells as innate immune cells

Xiaofeng Yang, N. Snyder, Jianxin Sun, 2022, Frontiers in Immunology.

Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation—Early Secretomes may Serve as Drivers for Trained Immunity

Xiaofeng Yang, S. Kunapuli, Hong Wang, 2022, Frontiers in Immunology.

Lysophospholipids and Their Receptors Serve as Conditional DAMPs and DAMP Receptors in Tissue Oxidative and Inflammatory Injury.

Hong Wang, Joon-Young Park, Jiali Cheng, 2017, Antioxidants & redox signaling.

Rare combination of dilated cardiomyopathy and ankylosing spondylitis in a family

Ying Sun, Wei Huang, Ying Shao, 2018, Journal of geriatric cardiology : JGC.

Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction- a novel mechanism for maintaining vascular function

Hong Wang, Hong Wang, Xiaofeng Yang, 2014, Journal of Hematology & Oncology.

Trained Immunity and Reactivity of Macrophages and Endothelial Cells.

Xiaofeng Yang, Yu Sun, Yifan Lu, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

David L. Williams, Xiaofeng Yang, N. Snyder, 2022, JCI insight.

Interlukin‐17A Promotes Aortic Endothelial Activation Via Transcriptionally and Post Transcriptionally Activating p38 MAPK Pathway

Hong Wang, Y. Iwakura, Xiaofeng Yang, 2016 .

IL-35 promotes CD4+Foxp3+ Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms

E. Shevach, Xiaofeng Yang, William Y. Yang, 2021, JCI insight.

Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

Xiaofeng Yang, J. Saredy, Yu Sun, 2021, Frontiers in Immunology.

Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

Rongshan Li, Xiaofeng Yang, J. Saredy, 2021, Frontiers in Immunology.

29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses

G. Criner, Xiaofeng Yang, S. Kunapuli, 2022, Journal of immunology research.

ATVB IN FOCUS: Trained Immunity and Vascular Disease

Hong Wang, Xiaofeng Yang, Yu Sun, 2021 .

Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers.

Xiaofeng Yang, Yu Sun, Yifan Lu, 2020, Pharmacology & therapeutics.

A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors

Hong Wang, Xiaoshu Cheng, T. Bottiglieri, 2017, Journal of Hematology & Oncology.

Metabolic Diseases Downregulate the Majority of Histone Modification Enzymes, Making a Few Upregulated Enzymes Novel Therapeutic Targets—“Sand Out and Gold Stays”

Hong Wang, Xiaofeng Yang, Jianxin Sun, 2016, Journal of Cardiovascular Translational Research.

NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis

Fuqing Zeng, Zhang Yue, Ying Shao, 2018, Cellular Physiology and Biochemistry.

accurately predict atherosclerosis in mice Proteomic profiles of serum inflammatory markers

P. Tsao, D. Tilley, T. Kurita-Ochiai, 2015 .

Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators

D. Praticò, Xiaofeng Yang, Jianxin Sun, 2021, Frontiers in Cardiovascular Medicine.

Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cells.

Hong Wang, Xiaofeng Yang, Ying Shao, 2015, Translational research : the journal of laboratory and clinical medicine.

Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD

N. Jhala, Xiaofeng Yang, Yu Sun, 2021, Journal of immunology research.

Pathological conditions re-shape physiological Tregs into pathological Tregs

Hong Wang, Xiaofeng Yang, William Y. Yang, 2015, Burns & Trauma.

Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells – Novel qualification markers for chronic disease risk factors and conditional DAMPs

Daohai Yu, Xiaofeng Yang, Xinyuan Li, 2019, Redox biology.

IL-35 (Interleukin-35) Suppresses Endothelial Cell Activation by Inhibiting Mitochondrial Reactive Oxygen Species-Mediated Site-Specific Acetylation of H3K14 (Histone 3 Lysine 14)

Hong Wang, M. Maddaloni, Xiaofeng Yang, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice

P. Blackshear, Xiaofeng Yang, S. Lessner, 2020, Redox biology.

Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages

Hong Wang, Jiamin Zhuo, Y. Zhong, 2023, Frontiers in Immunology.

Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

Xiaofeng Yang, Yu Sun, Yifan Lu, 2021, Redox biology.

Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

Xiaofeng Yang, J. Saredy, Yu Sun, 2021, Frontiers in Immunology.

A Novel Subset of CD95+ Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity

Xiaofeng Yang, Pu Fang, Yu Sun, 2021, Frontiers in Immunology.

Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors

Daohai Yu, Xiaofeng Yang, J. Saredy, 2019, Front. Immunol..

MicroRNA-155 Deficiency Leads to Decreased Atherosclerosis, Increased White Adipose Tissue Obesity, and Non-alcoholic Fatty Liver Disease

Hong Wang, Ying-Xuan Yin, M. Tordoff, 2016, The Journal of Biological Chemistry.

Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling

Xiaofeng Yang, Pu Fang, William Y. Yang, 2019, Redox biology.

Lysophospholipid Receptors, as Novel Conditional Danger Receptors and Homeostatic Receptors Modulate Inflammation—Novel Paradigm and Therapeutic Potential

Hong Wang, Xiaofeng Yang, Xinyuan Li, 2016, Journal of Cardiovascular Translational Research.

End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

Daohai Yu, Yafeng Li, Rongshan Li, 2020, Redox biology.

HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation.

Ying Shao, F. Zhu, L. Bai, 2021, The international journal of biochemistry & cell biology.

Approaching Inflammation Paradoxes—Proinflammatory Cytokine Blockages Induce Inflammatory Regulators

Xiaofeng Yang, J. Saredy, William Y. Yang, 2020, Frontiers in Immunology.

Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immunity/Tolerance

Daohai Yu, Rongshan Li, Xiaofeng Yang, 2021, Journal of immunology research.

Editorial: Insights in cardiovascular therapeutics 2022—cardiovascular innate immunity

Xiaofeng Yang, Hong Wang, Yifan Lu, 2023, Frontiers in Cardiovascular Medicine.

Analyses of caspase-1-regulated transcriptomes in various tissues lead to identification of novel IL-1β-, IL-18- and sirtuin-1-independent pathways

Hong Wang, Jiali Cheng, Xiaofeng Yang, 2017, Journal of Hematology & Oncology.

miR-190 is upregulated in Epstein-Barr Virus type I latency and modulates cellular mRNAs involved in cell survival and viral reactivation.

Yan Wang, Ying Shao, Yan Yuan, 2014, Virology.

Chronic Kidney Disease Transdifferentiates Veins into a Specialized Immune–Endocrine Organ with Increased MYCN-AP1 Signaling

Hong Wang, Xiaofeng Yang, J. Zhuo, 2023, Cells.

Siglec-15 as multifunctional molecule involved in osteoclast differentiation, cancer immunity and microbial infection.

Ying Shao, Lei Zhu, Tao Yang, 2022, Progress in biophysics and molecular biology.

Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis

Hong Wang, Xiaofeng Yang, Yifan Lu, 2023, Redox biology.

ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development

Hong Wang, Xiaofeng Yang, Yu Sun, 2023, Frontiers in immunology.

Innate immunity of vascular smooth muscle cells contributes to two-wave inflammation in atherosclerosis, twin-peak inflammation in aortic aneurysms and trans-differentiation potential into 25 cell types

Yifan Lu, Ying Shao, Fatma Saaoud, 2024, Frontiers in immunology.

Protein-rich foods, sea foods, and gut microbiota amplify immune responses in chronic diseases and cancers - Targeting PERK as a novel therapeutic strategy for chronic inflammatory diseases, neurodegenerative disorders, and cancer.

Yifan Lu, Ying Shao, Fatma Saaoud, 2024, Pharmacology & therapeutics.

Editorial: Sex differences and cardiovascular therapeutics

Yifan Lu, Ying Shao, Fatma Saaoud, 2024, Frontiers in cardiovascular medicine.

Caspase-4/11 promotes hyperlipidemia and chronic kidney disease–accelerated vascular inflammation by enhancing trained immunity

Yu Sun, Yifan Lu, Charles Drummer Iv, 2024, JCI insight.

A new paradigm in intracellular immunology: Mitochondria emerging as leading immune organelles

Yifan Lu, Ying Shao, Fatma Saaoud, 2024, Redox biology.