Fatma Saaoud

发表

ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes

Xianwei Wang, Xiaofeng Yang, J. Saredy, 2020, Redox biology.

The Role Of Inflammation In Atherosclerosis

Fatma Saaoud, 2017 .

Ursolic acid enhances macrophage autophagy and attenuates atherogenesis[S]

B. Razani, S. Leng, Yuzhen Wang, 2016, Journal of Lipid Research.

Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment

B. Razani, Yuzhen Wang, T. Evans, 2017, Oncoimmunology.

Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury

A. Melnick, C. Papasian, M. Fu, 2017, Signal Transduction and Targeted Therapy.

Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

D. Praticò, Xiaofeng Yang, Jianxin Sun, 2021, Frontiers in Cardiovascular Medicine.

Cigarette smoke modulates inflammation and immunity via ROS-regulated trained immunity and trained tolerance mechanisms.

Xiaofeng Yang, Hong Wang, Ying Shao, 2022, Antioxidants & redox signaling.

Cigarette Smoke and Morphine Promote Treg Plasticity to Th17 via Enhancing Trained Immunity

Xiaofeng Yang, Hong Wang, Yifan Lu, 2022, Cells.

Liver Ischemia Reperfusion Injury, Enhanced by Trained Immunity, Is Attenuated in Caspase 1/Caspase 11 Double Gene Knockout Mice

K. Lau, A. Di Carlo, N. Jhala, 2020, Pathogens.

Vascular Endothelial Cells and Innate Immunity.

Xiaofeng Yang, J. Saredy, William Y. Yang, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Editorial: Endothelial cells as innate immune cells

Xiaofeng Yang, N. Snyder, Jianxin Sun, 2022, Frontiers in Immunology.

Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation—Early Secretomes may Serve as Drivers for Trained Immunity

Xiaofeng Yang, S. Kunapuli, Hong Wang, 2022, Frontiers in Immunology.

Trained Immunity and Reactivity of Macrophages and Endothelial Cells.

Xiaofeng Yang, Yu Sun, Yifan Lu, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

David L. Williams, Xiaofeng Yang, N. Snyder, 2022, JCI insight.

The Microbial Metabolite Trimethylamine N-Oxide Links Vascular Dysfunctions and the Autoimmune Disease Rheumatoid Arthritis

Xiaofeng Yang, Yu Sun, Fatma Saaoud, 2019, Nutrients.

IL-35 promotes CD4+Foxp3+ Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms

E. Shevach, Xiaofeng Yang, William Y. Yang, 2021, JCI insight.

MiR155 modulates vascular calcification by regulating Akt‐FOXO3a signalling and apoptosis in vascular smooth muscle cells

S. Lessner, Yuzhen Wang, X. Kong, 2020, Journal of cellular and molecular medicine.

Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

Xiaofeng Yang, J. Saredy, Yu Sun, 2021, Frontiers in Immunology.

Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

Rongshan Li, Xiaofeng Yang, J. Saredy, 2021, Frontiers in Immunology.

29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses

G. Criner, Xiaofeng Yang, S. Kunapuli, 2022, Journal of immunology research.

ATVB IN FOCUS: Trained Immunity and Vascular Disease

Hong Wang, Xiaofeng Yang, Yu Sun, 2021 .

Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers.

Xiaofeng Yang, Yu Sun, Yifan Lu, 2020, Pharmacology & therapeutics.

Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators

D. Praticò, Xiaofeng Yang, Jianxin Sun, 2021, Frontiers in Cardiovascular Medicine.

Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD

N. Jhala, Xiaofeng Yang, Yu Sun, 2021, Journal of immunology research.

Emodin attenuates systemic and liver inflammation in hyperlipidemic mice administrated with lipopolysaccharides

Jun Hu, Yuzhen Wang, Fatma Saaoud, 2014, Experimental biology and medicine.

Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells – Novel qualification markers for chronic disease risk factors and conditional DAMPs

Daohai Yu, Xiaofeng Yang, Xinyuan Li, 2019, Redox biology.

Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice

P. Blackshear, Xiaofeng Yang, S. Lessner, 2020, Redox biology.

Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages

Hong Wang, Jiamin Zhuo, Y. Zhong, 2023, Frontiers in Immunology.

Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

Xiaofeng Yang, Yu Sun, Yifan Lu, 2021, Redox biology.

Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

Xiaofeng Yang, J. Saredy, Yu Sun, 2021, Frontiers in Immunology.

A Novel Subset of CD95+ Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity

Xiaofeng Yang, Pu Fang, Yu Sun, 2021, Frontiers in Immunology.

Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors

Daohai Yu, Xiaofeng Yang, J. Saredy, 2019, Front. Immunol..

Overexpression of microRNA-155 enhances the efficacy of dendritic cell vaccine against breast cancer

M. Luo, Qing Liu, F. Wang, 2020, Oncoimmunology.

End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

Daohai Yu, Yafeng Li, Rongshan Li, 2020, Redox biology.

Approaching Inflammation Paradoxes—Proinflammatory Cytokine Blockages Induce Inflammatory Regulators

Xiaofeng Yang, J. Saredy, William Y. Yang, 2020, Frontiers in Immunology.

Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immunity/Tolerance

Daohai Yu, Rongshan Li, Xiaofeng Yang, 2021, Journal of immunology research.

Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs

Jun Hu, Yuzhen Wang, Fatma Saaoud, 2014, Breast Cancer Research and Treatment.

Editorial: Insights in cardiovascular therapeutics 2022—cardiovascular innate immunity

Xiaofeng Yang, Hong Wang, Yifan Lu, 2023, Frontiers in Cardiovascular Medicine.

Adiporedoxin suppresses endothelial activation via inhibiting MAPK and NF-κB signaling

D. Maulik, C. Papasian, M. Fu, 2016, Scientific Reports.

Chronic Kidney Disease Transdifferentiates Veins into a Specialized Immune–Endocrine Organ with Increased MYCN-AP1 Signaling

Hong Wang, Xiaofeng Yang, J. Zhuo, 2023, Cells.

Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis

Hong Wang, Xiaofeng Yang, Yifan Lu, 2023, Redox biology.

ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development

Hong Wang, Xiaofeng Yang, Yu Sun, 2023, Frontiers in immunology.

Innate immunity of vascular smooth muscle cells contributes to two-wave inflammation in atherosclerosis, twin-peak inflammation in aortic aneurysms and trans-differentiation potential into 25 cell types

Yifan Lu, Ying Shao, Fatma Saaoud, 2024, Frontiers in immunology.

Protein-rich foods, sea foods, and gut microbiota amplify immune responses in chronic diseases and cancers - Targeting PERK as a novel therapeutic strategy for chronic inflammatory diseases, neurodegenerative disorders, and cancer.

Yifan Lu, Ying Shao, Fatma Saaoud, 2024, Pharmacology & therapeutics.