X. Liao

发表

Augmenter of liver regeneration protects the kidney from ischaemia‐reperfusion injury in ferroptosis

Li-li Huang, Hang Sun, X. Liao, 2019, Journal of cellular and molecular medicine.

Augmenter of liver regeneration protects kidneys from ischaemia/reperfusion injury in rats.

Hui Guo, Hang Sun, X. Liao, 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Effects and molecular mechanism of pachymic acid on ferroptosis in renal ischemia reperfusion injury

Li-li Huang, X. Liao, Gui-Ping Jiang, 2020, Molecular medicine reports.

Thyroid hormone receptor α and regulation of type 3 deiodinase.

R. Weiss, S. Refetoff, X. Liao, 2011, Molecular endocrinology.

Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice.

M. Leow, B. Singh, Sujoy Ghosh, 2016, Endocrinology.

XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes.

P. Arvan, Mingyao Liu, S. Refetoff, 2021, Thyroid : official journal of the American Thyroid Association.

Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways.

G. Shulman, J. Baxter, P. Webb, 2013, American journal of physiology. Endocrinology and metabolism.

Mct8-deficient mice have increased energy expenditure and reduced fat mass that is abrogated by normalization of serum T3 levels.

R. Weiss, S. Refetoff, X. Liao, 2013, Endocrinology.

Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation.

S. Larson, N. Rosen, D. Chakravarty, 2011, The Journal of clinical investigation.

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors

C. Montagna, A. Di Cristofano, S. Refetoff, 2011, Oncotarget.

Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function.

Shinjae Chung, O. Civelli, S. Refetoff, 2012, Endocrinology.

Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.

R. Weiss, S. Refetoff, N. Philp, 2010, The Journal of clinical investigation.

Expression of Augmenter of Liver Regeneration in Rats with Gentamicin-Induced Acute Renal Failure and Its Protective Effect on Kidney

Hang Sun, X. Liao, Qi Liu, 2009, Renal failure.

Augmenter of Liver Regeneration Attenuates Tubular Cell Apoptosis in Acute Kidney Injury in Rats: The Possible Mechanisms

Y. Li, Hui Guo, Hang Sun, 2012, Renal failure.

Angiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule Cells

Hui Guo, X. Liao, Qi Liu, 2016, PloS one.

Augmenter of liver regeneration inhibits TGF-β1-induced renal tubular epithelial-to-mesenchymal transition via suppressing TβR II expression in vitro.

Hui Guo, Hang Sun, X. Liao, 2014, Experimental cell research.

Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo.

A. Di Cristofano, S. Refetoff, K. Miller, 2009, Cancer research.

The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis.

A. Rosenzweig, Benjamin A. Rodwin, A. Hollenberg, 2011, Molecular endocrinology.

Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism.

C. Anderson, M. Ojaniemi, J. Kero, 2018, JCI insight.

Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor.

L. Moeller, S. Refetoff, T. Kusakabe, 2003, Molecular endocrinology.

Augmenter of Liver Regeneration Protects Renal Tubular Epithelial Cells From Ischemia-Reperfusion Injury by Promoting PINK1/Parkin-Mediated Mitophagy

Hang Sun, X. Liao, Qi Liu, 2020, Frontiers in Physiology.

A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene.

K. Brockmann, S. Refetoff, X. Liao, 2004, American journal of human genetics.

Increased ALK activity induces a poorly differentiated thyroid carcinoma in mice.

K. Schmid, J. Schulte, J. Kero, 2019, Thyroid : official journal of the American Thyroid Association.

SWI/SNF complex mutations promote thyroid tumor progression and insensitivity to redifferentiation therapies.

R. Koche, A. Ho, J. Fagin, 2020, Cancer discovery.

Abnormalities of the hypothalamo-pituitary-thyroid axis in the pro-opiomelanocortin deficient mouse

N. Martin, S. Bloom, M. Ghatei, 2004, Regulatory Peptides.

Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females

A. Di Cristofano, S. Refetoff, X. Liao, 2010, Oncogene.

Role of type 2 deiodinase in response to acute lung injury (ALI) in mice

J. Garcia, R. Weiss, S. Refetoff, 2011, Proceedings of the National Academy of Sciences.

Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8

A. Guadaño-Ferraz, S. Refetoff, X. Liao, 2019, PloS one.

Augmenter of liver regeneration regulates autophagy in renal ischemia–reperfusion injury via the AMPK/mTOR pathway

Hui Guo, Hang Sun, X. Liao, 2017, Apoptosis.

Dominant Role of Thyrotropin-releasing Hormone in the Hypothalamic-Pituitary-Thyroid Axis*

F. Wondisford, M. Mori, M. Yamada, 2006, Journal of Biological Chemistry.

Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo

H. Fuchs, L. Grøntved, D. Armstrong, 2017, Proceedings of the National Academy of Sciences.

Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice

K. Schmid, J. Schulte, D. Führer, 2019 .

A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.

P. Courtoy, C. Antignac, S. Cherqui, 2015, Endocrinology.

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

V. Detours, G. Van Simaeys, G. Doumont, 2021, bioRxiv.

A Liver-Speciﬁc Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia

D. Koeberl, S. Refetoff, P. Yen, 2019 .

In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.

F. Wondisford, R. Weiss, S. Refetoff, 2009, Endocrinology.

Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels

P. Kopp, D. Chartoumpekis, S. Refetoff, 2020, Thyroid : official journal of the American Thyroid Association.

An Essential Physiological Role for MCT8 in Bone in Male Mice

A. Boyde, P. Croucher, R. Weiss, 2017, Endocrinology.

A liver-specific thyromimetic, VK2809, decreases hepatosteatosis in glycogen storage disease type Ia (GSD Ia).

D. Koeberl, S. Refetoff, P. Yen, 2019, Thyroid : official journal of the American Thyroid Association.

Distinct roles of deiodinases on the phenotype of Mct8 defect: a comparison of eight different mouse genotypes.

R. Weiss, S. Refetoff, X. Liao, 2011, Endocrinology.

Pituitary-thyroid setpoint and thyrotropin receptor expression in consomic rats.

R. Weiss, L. Moeller, S. Refetoff, 2007, Endocrinology.

Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.

K. Millen, R. Weiss, S. Refetoff, 2006, Endocrinology.

A De Novo Mutation in an Already Mutant Nucleotide of the Thyroid Hormone Receptor β Gene Perpetuates Resistance to Thyroid Hormone

A. Verloes, R. Weiss, S. Refetoff, 2005 .

Mutations of the thyroid hormone transporter MCT8 cause prenatal brain damage and persistent hypomyelination.

D. Lev, J. Bernal, A. Guadaño-Ferraz, 2014, The Journal of clinical endocrinology and metabolism.

Mice deficient in dual oxidase maturation factors are severely hypothyroid.

S. Refetoff, X. Liao, H. Grasberger, 2012, Molecular endocrinology.

Augmenter of liver regeneration ameliorates renal fibrosis in rats with obstructive nephropathy

Hui Guo, Hang Sun, X. Liao, 2014, Bioscience reports.

Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2020 .

Vps34 PI 3-kinase controls thyroid hormone production by regulating thyroglobulin iodination, lysosomal proteolysis and tissue homeostasis.

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2020, Thyroid : official journal of the American Thyroid Association.

Vps34 PI 3-kinase controls thyroid hormone production by regulating thyroglobulin iodination, lysosomal proteolysis and tissue homeostasis

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2019, bioRxiv.

Vps34 PI 3-kinase controls thyroid hormone production by regulating thyroglobulin iodination, lysosomal proteolysis and tissue homeostasis

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2019, bioRxiv.

AAV9-MCT8 delivery at juvenile stage ameliorates neurological and behavioral deficits in an Allan-Herndon-Dudley Syndrome mouse model

C. Svendsen, B. Kaspar, S. Refetoff, 2021, bioRxiv.

Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface.

F. Wondisford, N. Shibusawa, S. Refetoff, 2005, The Journal of clinical investigation.

Augmenter of liver regeneration plays a protective role against hydrogen peroxide-induced oxidative stress in renal proximal tubule cells

N. Xia, Hui Guo, Hang Sun, 2015, Apoptosis.

Augmenter of liver regeneration protects the kidney against ischemia-reperfusion injury by inhibiting necroptosis

X. Liao, Zheng Zhang, Yue-Juan Liao, 2022, Bioengineered.

Mosaicism of a thyroid hormone receptor-beta gene mutation in resistance to thyroid hormone.

R. Weiss, S. Refetoff, X. Liao, 2006, The Journal of clinical endocrinology and metabolism.

Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice

R. Weiss, L. Moeller, S. Refetoff, 2017, The Journal of clinical endocrinology and metabolism.

Effects of maternal levels of thyroid hormone (TH) on the hypothalamus-pituitary-thyroid set point: studies in TH receptor beta knockout mice.

R. Weiss, S. Refetoff, X. Liao, 2007, Endocrinology.

A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport.

R. Weiss, S. Refetoff, X. Liao, 2009, Endocrinology.

Overexpression of augmenter of liver regeneration (ALR) mitigates the effect of H2O2-induced endoplasmic reticulum stress in renal tubule epithelial cells

Li-li Huang, Hang Sun, X. Liao, 2019, Apoptosis.

American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models.

David S. Sharlin, D. Sharlin, D. Forrest, 2014, Thyroid : official journal of the American Thyroid Association.

Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo.

F. Wondisford, M. Liberman, K. Hashimoto, 2003, The Journal of clinical investigation.

Clinical and molecular characterization of a novel selenocysteine insertion sequence-binding protein 2 (SBP2) gene mutation (R128X).

K. Khanna, R. Weiss, S. Refetoff, 2009, The Journal of clinical endocrinology and metabolism.

Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model.

P. Courtoy, S. Cherqui, P. van der Smissen, 2016, Endocrinology.

Tissue-specific posttranslational modification allows functional targeting of thyrotropin.

Masanobu Yamada, Yuka Ito, Hiroko Ono, 2014, Cell reports.

Tissue-Specific Posttrans lational Modification Allows Functional Targeting of Thyrotropin Graphical

H. Ono, Y. Shigeyoshi, M. Yamada, 2014 .

Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis.

Samuel Refetoff, S. Refetoff, X. Liao, 2007, Endocrinology.

Thyroid regeneration: characterization of clear cells after partial thyroidectomy.

K. Nagashima, S. Thorgeirsson, J. Rodriguez-Canales, 2012, Endocrinology.

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

Emma Lundsmith, Samuel Refetoff, Neal Rosen, 2011, Proceedings of the National Academy of Sciences.

Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression.

A. Di Cristofano, R. Ghossein, S. Refetoff, 2014, Endocrine-related cancer.

Generation of functional thyroid from embryonic stem cells

Michael Kyba, Samuel Refetoff, Mario Manto, 2012, Nature.

Analysis of the PAX8 Gene in Congenital Hypothyroidism Caused by Different Forms of Thyroid Dysgenesis in a Father and Daughter

S. Refetoff, X. Liao, A. Bereket, 2004, Journal of pediatric endocrinology & metabolism : JPEM.

Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.

J. Dumont, F. Miot, B. Corvilain, 2016, Thyroid : official journal of the American Thyroid Association.

Masayuki Yamamoto, I. Trougakos, D. Chartoumpekis, 2018, Thyroid : official journal of the American Thyroid Association.

Prenatal treatment of thyroid hormone cell membrane transport defect caused by MCT8 gene mutation.

J. Bernal, K. Hansen, R. Weiss, 2020, Thyroid : official journal of the American Thyroid Association.

Adeno Associated Virus 9-Based Gene Therapy Delivers a Functional Monocarboxylate Transporter 8, Improving Thyroid Hormone Availability to the Brain of Mct8-Deficient Mice.

A. Guadaño-Ferraz, B. Kaspar, R. Weiss, 2016, Thyroid : official journal of the American Thyroid Association.

Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.

J. Bernal, R. Weiss, S. Refetoff, 2014, Endocrinology.

OR01-01 Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism

A. Bianco, S. Refetoff, X. Liao, 2020, Thyroid : official journal of the American Thyroid Association.

Changes in thyroid status during perinatal development of MCT8-deficient male mice.

J. Bernal, R. Weiss, S. Refetoff, 2013, Endocrinology.

The syndrome of inherited partial SBP2 deficiency in humans.

R. Weiss, S. Refetoff, X. Liao, 2010, Antioxidants & redox signaling.

Mutations in SECISBP2 result in abnormal thyroid hormone metabolism

L. Schomburg, R. Weiss, L. Moeller, 2005, Nature Genetics.

Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.

Lei Zhang, Yuri E Nikiforov, Samuel Refetoff, 2005, Cancer research.

The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo.

M. Lazar, S. You, R. Weiss, 2010, Molecular endocrinology.

Selenium supplementation fails to correct the selenoprotein synthesis defect in subjects with SBP2 gene mutations.

L. Schomburg, J. Köhrle, S. Refetoff, 2009, Thyroid : official journal of the American Thyroid Association.

AAV9-MCT8 delivery at juvenile stage ameliorates neurological and behavioral deficits in a mouse model of MCT8-deficiency.

C. Svendsen, B. Kaspar, S. Refetoff, 2022, Thyroid : official journal of the American Thyroid Association.

GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation

Raja Jothi, H. S. Kang, Dhirendra Kumar, 2017, The Journal of clinical investigation.

TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice

Xiaoping Zhou, J. Wit, M. Wade, 2017, Endocrinology.

Augmenter of liver regeneration promotes mitochondrial biogenesis in renal ischemia–reperfusion injury

Hui Guo, Hang Sun, X. Liao, 2018, Apoptosis.

Augmenter of Liver Regeneration Alleviates Renal Hypoxia-Reoxygenation Injury by Regulating Mitochondrial Dynamics in Renal Tubular Epithelial Cells

Li-li Huang, Hang Sun, X. Liao, 2019, Molecules and cells.

Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 Deficiency

X. Liao, A. Dumitrescu, Jiao Fu, 2017, Endocrinology.

Thyroid Hormone Receptor (cid:1) and Regulation of Type 3 Deiodinase

R. Weiss, S. Refetoff, X. Liao, 2011 .

Maintaining the thyroid gland in mutant thyroglobulin–induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood

Ming Liu, P. Arvan, S. Refetoff, 2022, The Journal of biological chemistry.

The Thyroid Hormone Analog DITPA Ameliorates Metabolic Parameters of Male Mice With Mct8 Deficiency.

R. Weiss, S. Refetoff, X. Liao, 2015, Endocrinology.

Augmenter of liver regeneration promotes mitochondrial biogenesis in renal ischemia–reperfusion injury

Li-li Huang, Hui Guo, Hang Sun, 2018, Apoptosis.

Augmenter of liver regeneration plays a protective role against hydrogen peroxide-induced oxidative stress in renal proximal tubule cells

N. Xia, Hui Guo, Hang Sun, 2015, Apoptosis.

Role of GLIS3 in thyroid development and in the regulation of gene expression in thyroid specific Glis3KO mice

Sara A. Grimm, H. S. Kang, A. Jetten, 2023, Research square.

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.

M. Leow, B. Singh, S. Refetoff, 2017, Thyroid : official journal of the American Thyroid Association.

Clinical and Molecular Analysis in 2 Families With Novel Compound Heterozygous SBP2 (SECISBP2) Mutations.

R. Weiss, K. Burman, A. Alikaşifoğlu, 2020, The Journal of clinical endocrinology and metabolism.

A de novo mutation in an already mutant nucleotide of the thyroid hormone receptor beta gene perpetuates resistance to thyroid hormone.

A. Verloes, R. Weiss, S. Refetoff, 2005, The Journal of clinical endocrinology and metabolism.

Role Of The Thyroid Gland In Expression Of The Thyroid Phenotype Of Sbp2 Deficient Mice.

X. Liao, A. Dumitrescu, Jiao Fu, 2019, Endocrinology.

Augmenter of liver regeneration regulates autophagy in renal ischemia–reperfusion injury via the AMPK/mTOR pathway

Hui Guo, Hang Sun, X. Liao, 2017, Apoptosis.

Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland

P. Arvan, Y. Tomer, S. Refetoff, 2023, JCI insight.

Effect of the Fetal THRB Genotype on the Placenta.

F. Salas-Lucia, S. Refetoff, X. Liao, 2023, The Journal of clinical endocrinology and metabolism.

Iodotyrosines are biomarkers for preclinical stages of iodine-deficient hypothyroidism in Dehal1 knockout mice.

A. Saba, Andrea Bertolini, S. Refetoff, 2023, Thyroid.