C. Dutra-filho

发表

Promotion of oxidative stress in kidney of rats loaded with cystine dimethyl ester

M. Wajner, V. Rech, L. Feksa, 2007, Pediatric Nephrology.

Experimental hyperprolinemia induces mild oxidative stress, metabolic changes, and tissue adaptation in rat liver

A. G. Ferreira, A. Wyse, C. Dutra-filho, 2012, Journal of cellular biochemistry.

Evidence that 2-methylacetoacetate induces oxidative stress in rat brain

G. Leipnitz, M. Wajner, C. Fernandes, 2010, Metabolic Brain Disease.

Evidence that the major metabolites accumulating in hyperornithinemia–hyperammonemia–homocitrullinuria syndrome induce oxidative stress in brain of young rats

G. Leipnitz, M. Wajner, C. Fernandes, 2009, International Journal of Developmental Neuroscience.

Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain

M. Wajner, C. Dutra-filho, P. F. Schuck, 2009, Neurochemistry International.

Chronic Exposure to β-Alanine Generates Oxidative Stress and Alters Energy Metabolism in Cerebral Cortex and Cerebellum of Wistar Rats

M. Wajner, C. Dutra-filho, C. Wannmacher, 2018, Molecular Neurobiology.

Inhibition of energy productionin vitro by glutaric acid in cerebral cortex of young rats

M. Wajner, C. Ruschel, A. Wyse, 2000, Metabolic Brain Disease.

Effect of collection, transport, processing and storage of blood specimens on the activity of lysosomal enzymes in plasma and leukocytes.

R. Giugliani, C. Dutra-filho, M. Burin, 2000, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Differential inhibitory effects of methylmalonic acid on respiratory chain complex activities in rat tissues

M. Wajner, A. Wyse, C. Dutra-filho, 2006, International Journal of Developmental Neuroscience.

Inhibition of Glutamate Uptake into Synaptic Vesicles from Rat Brain by 3-Nitropropionic Acid in Vitro

D. Souza, M. Wajner, R. Tavares, 2001, Experimental Neurology.

Creatine and Pyruvate Prevent the Alterations Caused by Tyrosine on Parameters of Oxidative Stress and Enzyme Activities of Phosphoryltransfer Network in Cerebral Cortex of Wistar Rats

C. Dutra-filho, C. Wannmacher, R. B. Andrade, 2014, Molecular Neurobiology.

Cysteamine prevents and reverses the inhibition of creatine kinase activity caused by cystine in rat brain cortex

M. Wajner, A. Wyse, C. Dutra-filho, 2005, Neurochemistry International.

Experimental hyperphenylalaninemia provokes oxidative stress in rat brain.

M. Wajner, A. Wyse, C. Dutra-filho, 2002, Biochimica et biophysica acta.

The role of oxidative damage in the neuropathology of organic acidurias: Insights from animal studies

M. Wajner, A. Wyse, C. Dutra-filho, 2004, Journal of Inherited Metabolic Disease.

ACUTE AEROBIC EXERCISE RESTORES TRYPTOPHAN CONCENTRATION IN THE BRAIN OF RATS WITH HYPERPHENYLALANINEMIA

C. Dutra-filho, C. Pederzolli, T. Moraes, 2012 .

N-Acetylaspartic acid promotes oxidative stress in cerebral cortex of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2007, International Journal of Developmental Neuroscience.

Hypermethioninemia provokes oxidative damage and histological changes in liver of rats.

C. Matté, A. Wyse, F. Stefanello, 2009, Biochimie.

Evaluation of Oxidative Stress Parameters and Energy Metabolism in Cerebral Cortex of Rats Subjected to Sarcosine Administration

M. Wajner, A. Wyse, C. Dutra-filho, 2016, Molecular Neurobiology.

Brain zinc chelation by diethyldithiocarbamate increased the behavioral and mitochondrial damages in zebrafish subjected to hypoxia

D. Souza, C. Dutra-filho, D. B. Rosemberg, 2016, Scientific Reports.

L-Carnitine supplementation decreases DNA damage in treated MSUD patients.

C. Vargas, M. Wajner, C. Dutra-filho, 2015, Mutation research.

Urinary biomarkers of oxidative damage in Maple syrup urine disease: The l-carnitine role

A. Sitta, C. Vargas, M. Wajner, 2015, International Journal of Developmental Neuroscience.

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

C. Vargas, M. Wajner, C. Dutra-filho, 2015 .

Prevention of DNA damage by L-carnitine induced by metabolites accumulated in maple syrup urine disease in human peripheral leukocytes in vitro.

C. Vargas, C. Dutra-filho, C. Mescka, 2014, Gene.

Diabetic encephalopathy‐related depression: experimental evidence that insulin and clonazepam restore antioxidant status in rat brain

C. Vargas, C. Dutra-filho, C. Mescka, 2014, Cell biochemistry and function.

Protein and lipid damage in maple syrup urine disease patients: l-carnitine effect

C. Vargas, M. Wajner, C. Dutra-filho, 2013, International Journal of Developmental Neuroscience.

Pipecolic acid induces oxidative stress in vitro in cerebral cortex of young rats and the protective role of lipoic acid

C. Dutra-filho, G. Dalazen, C. Jacques, 2014, Metabolic Brain Disease.

Administration of Histidine to Female Rats Induces Changes in Oxidative Status in Cortex and Hippocampus of the Offspring

C. Dutra-filho, C. Wannmacher, R. B. Andrade, 2012, Neurochemical Research.

Role of Catalase and Superoxide Dismutase Activities on Oxidative Stress in the Brain of a Phenylketonuria Animal Model and the Effect of Lipoic Acid

C. Dutra-filho, G. Dalazen, T. Moraes, 2012, Cellular and Molecular Neurobiology.

Pyruvate and creatine prevent oxidative stress and behavioral alterations caused by phenylalanine administration into hippocampus of rats

C. Dutra-filho, C. Wannmacher, T. Moraes, 2012, Metabolic Brain Disease.

Chronic hyperhomocysteinemia induces oxidative damage in the rat lung

A. G. Ferreira, A. Wyse, C. Dutra-filho, 2011, Molecular and Cellular Biochemistry.

In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease

C. Dutra-filho, C. Mescka, G. Dalazen, 2011, Metabolic Brain Disease.

Inhibition of creatine kinase activity from rat cerebral cortex by 3-hydroxykynurenine

V. Rodrigues-Junior, M. Wajner, A. Wyse, 2006, Brain Research.

Effects of methylmalonic and propionic acids on glutamate uptake by synaptosomes and synaptic vesicles and on glutamate release by synaptosomes from cerebral cortex of rats

D. Souza, M. Wajner, T. Emanuelli, 2001, Brain Research.

Guanidinoacetate Decreases Antioxidant Defenses and Total Protein Sulfhydryl Content in Striatum of Rats

M. Wajner, A. Wyse, F. Stefanello, 2008, Neurochemical Research.

Sulfite increases lipoperoxidation and decreases the activity of catalase in brain of rats

A. Wyse, C. Dutra-filho, C. Netto, 2008, Metabolic Brain Disease.

Erythrocyte glutathione peroxidase activity and plasma selenium concentration are reduced in maple syrup urine disease patients during treatment

A. Sitta, C. Vargas, M. Wajner, 2007, International Journal of Developmental Neuroscience.

Investigation of oxidative stress parameters in treated phenylketonuric patients

A. Sitta, C. Vargas, M. Wajner, 2006, Metabolic Brain Disease.

Oxidative stress in patients with phenylketonuria.

A. Sitta, C. Vargas, M. Wajner, 2005, Biochimica et biophysica acta.

Induction of oxidative stress by L‐2‐hydroxyglutaric acid in rat brain

G. Leipnitz, M. Wajner, A. Belló-Klein, 2003, Journal of neuroscience research.

In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain

G. Leipnitz, M. Wajner, A. Wyse, 2007, Neurochemistry International.

Promotion of oxidative stress by l-tryptophan in cerebral cortex of rats

M. Wajner, A. Wyse, V. Rech, 2006, Neurochemistry International.

Oxidative stress in plasma from maple syrup urine disease patients during treatment

A. Sitta, C. Vargas, M. Wajner, 2008, Metabolic Brain Disease.

Evidence that oxidative stress is increased in plasma from patients with maple syrup urine disease

A. Sitta, C. Vargas, M. Wajner, 2006, Metabolic Brain Disease.

In vitro stimulation of oxidative stress in cerebral cortex of rats by the guanidino compounds accumulating in hyperargininemia

M. Wajner, A. Wyse, C. Dutra-filho, 2001, Brain Research.

Inhibition of brain energy metabolism by the alpha-keto acids accumulating in maple syrup urine disease.

M. Wajner, C. Ribeiro, A. Wyse, 2003, Biochimica et biophysica acta.

Na+, K+ ATPase activity is markedly reduced by cis-4-decenoic acid in synaptic plasma membranes from cerebral cortex of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2006, Experimental Neurology.

Effect of histidine administration to female rats during pregnancy and lactation on enzymes activity of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring

C. Dutra-filho, C. Wannmacher, R. B. Andrade, 2012, Metabolic Brain Disease.

Protective effect of antioxidants on brain oxidative damage caused by proline administration

M. Wajner, A. Wyse, C. Dutra-filho, 2005, Neuroscience Research.

Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease

M. Wajner, R. Tavares, C. Tasca, 2000, Journal of the Neurological Sciences.

Preliminary results of PBA-loaded nanoparticles development and the effect on oxidative stress and neuroinflammation in rats submitted to a chemically induced chronic model of MSUD

A. Sitta, C. Vargas, B. Donida, 2021, Metabolic Brain Disease.

L-carnitine Prevents Oxidative Stress in the Brains of Rats Subjected to a Chemically Induced Chronic Model of MSUD

A. Sitta, C. Vargas, C. Dutra-filho, 2015, Molecular Neurobiology.

Phenylalanine induces oxidative stress and decreases the viability of rat astrocytes: possible relevance for the pathophysiology of neurodegeneration in phenylketonuria

I. J. Bristot, J. Moreira, C. Dutra-filho, 2015, Metabolic Brain Disease.

Lipoic acid prevents oxidative stress in vitro and in vivo by an acute hyperphenylalaninemia chemically-induced in rat brain

M. Wajner, C. Dutra-filho, T. Moraes, 2010, Journal of the Neurological Sciences.

Tryptophan administration induces oxidative stress in brain cortex of rats

G. Leipnitz, M. Wajner, V. Rech, 2008, Metabolic Brain Disease.

Influence of ketone bodies on oxidative stress parameters in brain of developing rats in vitro

G. Leipnitz, C. Vargas, M. Wajner, 2008, Metabolic Brain Disease.

Effects of cysteamine on oxidative status in cerebral cortex of rats

M. Wajner, V. Rech, L. Feksa, 2008, Metabolic Brain Disease.

Promotion of oxidative stress by 3-hydroxyglutaric acid in rat striatum

G. Leipnitz, M. Wajner, C. Dutra-filho, 2005, Journal of Inherited Metabolic Disease.

Tyrosine impairs enzymes of energy metabolism in cerebral cortex of rats

C. Dutra-filho, C. Wannmacher, R. B. Andrade, 2012, Molecular and Cellular Biochemistry.

Inhibition of Brain Energy Metabolism by the Branched-chain Amino Acids Accumulating in Maple Syrup Urine Disease

M. Wajner, C. Ribeiro, C. Dutra-filho, 2007, Neurochemical Research.

Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism

C. Vargas, M. Wajner, A. Wyse, 2007, International Journal of Developmental Neuroscience.

Alanine Prevents the in Vitro Inhibition of Glycolysis Caused by Phenylalanine in Brain Cortex of Rats

M. Wajner, L. Feksa, C. Dutra-filho, 2003, Metabolic Brain Disease.

Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats.

M. Wajner, C. Dutra-filho, C. Wannmacher, 1991, Biochemical medicine and metabolic biology.

Acute administration of 5-oxoproline induces oxidative damage to lipids and proteins and impairs antioxidant defenses in cerebral cortex and cerebellum of young rats

C. Vargas, M. Wajner, C. Dutra-filho, 2010, Metabolic Brain Disease.

5-Oxoproline Reduces Non-Enzymatic Antioxidant Defenses in vitro in Rat Brain

M. Wajner, A. Wyse, C. Dutra-filho, 2007, Metabolic Brain Disease.

Monosialoganglioside Increases Catalase Activity in Cerebral Cortex of Rats

J. Bonini, C. Dutra-filho, M. R. Fighera, 2004, Free radical research.

Evidence That Antioxidants Prevent the Inhibition of Na+,K+-ATPase Activity Induced by Octanoic Acid in Rat Cerebral Cortex in Vitro

C. Vargas, M. Wajner, C. Ribeiro, 2003, Neurochemical Research.

Evidence that 3-hydroxyisobutyric acid inhibits key enzymes of energy metabolism in cerebral cortex of young rats

M. Wajner, A. Wyse, C. Dutra-filho, 2008, International Journal of Developmental Neuroscience.

Amino acids levels and lipid peroxidation in maple syrup urine disease patients.

A. Sitta, C. Vargas, M. Wajner, 2009, Clinical biochemistry.

Possible high frequency of tetrahydrobiopterin deficiency in South Brazil

N. Blau, R. Giugliani, C. Dutra-filho, 1994, Journal of Inherited Metabolic Disease.

Chronic postnatal administration of methylmalonic acid provokes a decrease of myelin content and ganglioside N-acetylneuraminic acid concentration in cerebrum of young rats.

M. Wajner, A. Wyse, C. Dutra-filho, 2001, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Chapter 6 Regular exercise prevents catecholamine and behavioral deficits in hyperphenylalaninemic rats

C. Dutra-filho, E. Casali, G. Dalazen, 2016 .

Induction of oxidative stress by the metabolites accumulating in isovaleric acidemia in brain cortex of young rats

G. Leipnitz, M. Wajner, C. Fernandes, 2008, Free radical research.

Reduction of large neutral amino acid levels in plasma and brain of hyperleucinemic rats

C. Vargas, M. Wajner, A. Wyse, 2001, Neurochemistry International.

α-Keto Acids Accumulating in Maple Syrup Urine Disease Stimulate Lipid Peroxidation and Reduce Antioxidant Defences in Cerebral Cortex From Young Rats

M. Wajner, C. Dutra-filho, C. Wannmacher, 2005, Metabolic Brain Disease.

Synaptic Plasma Membrane Na+, K+-ATPase Activity is Significantly Reduced by the α-Keto Acids Accumulating in Maple Syrup Urine Disease in Rat Cerebral Cortex

M. Wajner, C. Dutra-filho, C. Wannmacher, 2007, Metabolic Brain Disease.

Proline Administration Decreases Na+,K+-ATPase Activity in the Synaptic Plasma Membrane from Cerebral Cortex of Rats

M. Wajner, A. Wyse, C. Dutra-filho, 1999, Metabolic Brain Disease.

Alanine Prevents the Reduction of Pyruvate Kinase Activity in Brain Cortex of Rats Subjected to Chemically Induced Hyperphenylalaninemia

M. Wajner, A. Wyse, V. Rech, 2002, Neurochemical Research.

Energy Metabolism is Compromised in Skeletal Muscle of Rats Chronically-Treated with Glutaric Acid

C. Vargas, M. Wajner, A. Wyse, 2007, Metabolic Brain Disease.

L-Pyroglutamic Acid Inhibits Energy Production and Lipid Synthesis in Cerebral Cortex of Young Rats In Vitro

M. Wajner, C. Ruschel, A. Wyse, 2001, Neurochemical Research.

Tryptophan reduces creatine kinase activity in the brain cortex of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2004, International Journal of Developmental Neuroscience.

Inhibition of Creatine Kinase Activity by Cystine in the Kidney of Young Rats

V. Rodrigues-Junior, M. Wajner, A. Wyse, 2006, Pediatric Research.

The effects of the interactions between amino acids on pyruvate kinase activity from the brain cortex of young rats

M. Wajner, A. Wyse, L. Feksa, 2005, International Journal of Developmental Neuroscience.

Inhibition of pyruvate kinase activity by cystine in brain cortex of rats

M. Wajner, A. Wyse, L. Feksa, 2004, Brain Research.

Kinetic studies on the inhibition of creatine kinase activity by branched-chain α-amino acids in the brain cortex of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2003, International Journal of Developmental Neuroscience.

Platelet Na+,K+-ATPase activity as a possible peripheral marker for the neurotoxic effects of phenylalanine in phenylketonuria

M. Wajner, A. Wyse, C. Dutra-filho, 2000, Metabolic Brain Disease.

Reduced Na+,K+-ATPase Activity in Erythrocyte Membranes from Patients with Phenylketonuria

M. Wajner, A. Wyse, C. Dutra-filho, 2001, Pediatric Research.

Stimulation of Lipid Peroxidation in Vitro in Rat Brain by the Metabolites Accumulating in Maple Syrup Urine Disease

M. Wajner, C. Dutra-filho, C. Wannmacher, 2002, Metabolic Brain Disease.

Propionic and L‐methylmalonic acids induce oxidative stress in brain of young rats

M. Wajner, C. Dutra-filho, C. Wannmacher, 2000, Neuroreport.

Neonatal hyperglycemia induces oxidative stress in the rat brain: the role of pentose phosphate pathway enzymes and NADPH oxidase

C. Dutra-filho, C. Mescka, C. Jacques, 2015, Molecular and Cellular Biochemistry.

Phenylpyruvic Acid Decreases Glucose-6-Phosphate Dehydrogenase Activity in Rat Brain

C. Dutra-filho, T. Moraes, C. Jacques, 2012, Cellular and Molecular Neurobiology.

Hyperphenylalaninemia reduces creatine kinase activity in the cerebral cortex of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2003, International Journal of Developmental Neuroscience.

Effects of 1,4-butanediol administration on oxidative stress in rat brain: Study of the neurotoxicity of γ-hydroxybutyric acid in vivo

M. Wajner, A. Wyse, C. Dutra-filho, 2009, Metabolic Brain Disease.

Induction of oxidative stress in rat brain by the metabolites accumulating in maple syrup urine disease

M. Wajner, C. Dutra-filho, R. Bridi, 2003, International Journal of Developmental Neuroscience.

Quinolinic acid inhibits glutamate uptake into synaptic vesicles from rat brain

D. Souza, M. Wajner, R. Tavares, 2000, Neuroreport.

Evidence that 3‐hydroxy‐3‐methylglutaric acid promotes lipid and protein oxidative damage and reduces the nonenzymatic antioxidant defenses in rat cerebral cortex

G. Leipnitz, M. Wajner, B. Seminotti, 2008, Journal of neuroscience research.

Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats

M. Wajner, C. Dutra-filho, A. Latini, 2005, Free radical research.

Tyrosine impairs enzymes of energy metabolism in cerebral cortex of rats

C. Dutra-filho, C. Wannmacher, C. Funchal, 2012, Molecular and Cellular Biochemistry.

Pyruvate and creatine prevent oxidative stress and behavioral alterations caused by phenylalanine administration into hippocampus of rats

C. Dutra-filho, C. Wannmacher, T. Moraes, 2012, Metabolic Brain Disease.

Enzymatic scavengers in the epididymal fluid: comparison between pony and miniature breed stallions.

C. Dutra-filho, I. C. Bustamante-Filho, R. Mattos, 2014, Animal reproduction science.

A chemically-induced acute model of maple syrup urine disease in rats for neurochemical studies

C. Vargas, M. Wajner, C. Dutra-filho, 2006, Journal of Neuroscience Methods.

Antioxidant Effect of Cysteamine in Brain Cortex of Young Rats

M. Wajner, C. Dutra-filho, C. Wannmacher, 2008, Neurochemical Research.

Kynurenines Impair Energy Metabolism in Rat Cerebral Cortex

M. Wajner, C. Dutra-filho, A. Latini, 2007, Cellular and Molecular Neurobiology.

Characterization of the inhibition of pyruvate kinase caused by phenylalanine and phenylpyruvate in rat brain cortex

M. Wajner, A. Wyse, L. Feksa, 2003, Brain Research.

Effect of phenylalanine and p-chlorophenylalanine on Na+, K+-ATPase activity in the synaptic plasma membrane from the cerebral cortex of rats

A. Wyse, C. Dutra-filho, C. Wannmacher, 2000, Metabolic Brain Disease.

Inhibition of energy metabolism in cerebral cortex of young rats by the medium-chain fatty acids accumulating in MCAD deficiency

M. Wajner, C. Ribeiro, A. Wyse, 2004, Brain Research.

Ascorbic acid prevents cognitive deficits caused by chronic administration of propionic acid to rats in the water maze

M. Wajner, A. Wyse, C. Dutra-filho, 2002, Pharmacology Biochemistry and Behavior.

Inborn Errors of Metabolism

Roberto Giugliani, M. Wajner, R. Giugliani, 1989 .

Glutathione metabolism enzymes in brain and liver of hyperphenylalaninemic rats and the effect of lipoic acid treatment

C. Dutra-filho, G. Dalazen, T. Moraes, 2014, Metabolic Brain Disease.

Neonatal hyperglycemia induces cell death in the rat brain

C. Dutra-filho, C. Mescka, R. Teixeira, 2018, Metabolic Brain Disease.

Effects of Fish and Grape Seed Oils as Core of Haloperidol-Loaded Nanocapsules on Oral Dyskinesia in Rats

D. Benvegnú, T. Emanuelli, R. Beck, 2018, Neurochemical Research.

Acute biochemical and physiological responses to swimming training series performed at intensities based on the 400-m front crawl speed

C. Dutra-filho, Marcos Franken, P. Mazzola, 2018, Sport Sciences for Health.

Neonatal hyperglycemia induces oxidative stress in the rat brain: the role of pentose phosphate pathway enzymes and NADPH oxidase

C. Dutra-filho, C. Mescka, C. Jacques, 2015, Molecular and Cellular Biochemistry.

Chemically induced acute model of sarcosinemia in wistar rats

C. Dutra-filho, C. Wannmacher, D. Rojas, 2016, Metabolic Brain Disease.

Oxidative stress induction by cis-4-decenoic acid: Relevance for MCAD deficiency

G. Leipnitz, M. Wajner, C. Dutra-filho, 2007, Free radical research.

Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain.

M. Wajner, C. Ruschel, A. Wyse, 2001, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Citrulline and Ammonia Accumulating in Citrullinemia Reduces Antioxidant Capacity of Rat Brain In Vitro

M. Wajner, A. Wyse, C. Dutra-filho, 2006, Metabolic Brain Disease.

Arginine administration reduces catalase activity in midbrain of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2002, Neuroreport.

Phenylpyruvic Acid Decreases Glucose-6-Phosphate Dehydrogenase Activity in Rat Brain

C. Dutra-filho, T. Moraes, C. Jacques, 2012, Cellular and Molecular Neurobiology.

Inhibition of the Mitochondrial Respiratory Chain by Phenylalanine in Rat Cerebral Cortex

M. Wajner, A. Wyse, L. Feksa, 2002, Neurochemical Research.

Inhibition of the mitochondrial respiratory chain complex activities in rat cerebral cortex by methylmalonic acid

M. Wajner, C. Ribeiro, A. Wyse, 2002, Neurochemistry International.

Tyrosine inhibits creatine kinase activity in cerebral cortex of young rats

C. Dutra-filho, C. Wannmacher, C. Funchal, 2011, Metabolic Brain Disease.

Tyrosine administration decreases glutathione and stimulates lipid and protein oxidation in rat cerebral cortex

M. Wajner, A. Wyse, C. Dutra-filho, 2009, Metabolic Brain Disease.

Tyrosine promotes oxidative stress in cerebral cortex of young rats

M. Wajner, A. Wyse, C. Dutra-filho, 2008, International Journal of Developmental Neuroscience.

Creatine and Pyruvate Prevent the Alterations Caused by Tyrosine on Parameters of Oxidative Stress and Enzyme Activities of Phosphoryltransfer Network in Cerebral Cortex of Wistar Rats

C. Dutra-filho, C. Wannmacher, C. Funchal, 2014, Molecular Neurobiology.

Alanine Prevents the Inhibition of Pyruvate Kinase Activity Caused by Tryptophan in Cerebral Cortex of Rats

M. Wajner, L. Feksa, C. Dutra-filho, 2003, Metabolic Brain Disease.

Pipecolic acid induces oxidative stress in vitro in cerebral cortex of young rats and the protective role of lipoic acid

C. Dutra-filho, G. Dalazen, C. Jacques, 2014, Metabolic Brain Disease.

Role of Catalase and Superoxide Dismutase Activities on Oxidative Stress in the Brain of a Phenylketonuria Animal Model and the Effect of Lipoic Acid

C. Dutra-filho, G. Dalazen, T. Moraes, 2013, Cellular and Molecular Neurobiology.

Neuroprotective role of lipoic acid against acute toxicity of N-acetylaspartic acid

C. Dutra-filho, C. Pederzolli, G. Dalazen, 2010, Molecular and Cellular Biochemistry.

Induction of Oxidative Stress by Chronic and Acute Glutaric Acid Administration to Rats

C. Vargas, M. Wajner, C. Dutra-filho, 2007, Cellular and Molecular Neurobiology.

Age and Brain Structural Related Effects of Glutaric and 3-Hydroxyglutaric Acids on Glutamate Binding to Plasma Membranes During Rat Brain Development

D. Souza, G. Leipnitz, M. Wajner, 2007, Cellular and Molecular Neurobiology.

Proline Reduces Creatine Kinase Activity in the Brain Cortex of Rats

M. Wajner, C. Dutra-filho, Ângela Terezinha Souza Wyse, 2003, Neurochemical Research.

Effect of Proline on Creatine Kinase Activity in Rat Brain

M. Wajner, A. Wyse, C. Dutra-filho, 2003, Metabolic Brain Disease.

In Vitro Effect of Homocysteine on Some Parameters of Oxidative Stress in Rat Hippocampus

M. Wajner, A. Wyse, C. Dutra-filho, 2003, Metabolic Brain Disease.

Intracerebroventricular administration of N-acetylaspartic acid impairs antioxidant defenses and promotes protein oxidation in cerebral cortex of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2009, Metabolic Brain Disease.

Effect of Leucine Administration on Creatine Kinase Activity in Rat Brain

M. Wajner, A. Wyse, C. Dutra-filho, 2003, Metabolic Brain Disease.

In vivo and in vitro effects of proline on some parameters of oxidative stress in rat brain

M. Wajner, A. Wyse, C. Dutra-filho, 2003, Brain Research.

Evaluation of the effect of chronic administration of drugs on rat behavior in the water maze task.

M. Wajner, A. Wyse, C. Dutra-filho, 2003, Brain research. Brain research protocols.

Proline induces oxidative stress in cerebral cortex of rats

M. Wajner, A. Wyse, C. Dutra-filho, 2003, International Journal of Developmental Neuroscience.

γ-Hydroxybutyric acid induces oxidative stress in cerebral cortex of young rats

M. Wajner, A. Wyse, C. Dutra-filho, 2007, Neurochemistry International.

D‐2‐hydroxyglutaric acid induces oxidative stress in cerebral cortex of young rats

M. Wajner, A. Belló-Klein, C. Dutra-filho, 2003, The European journal of neuroscience.

Benzophenones from Hypericum carinatum.

A. Henriques, C. Dutra-filho, J. Schripsema, 2005, Journal of natural products.

Nitric Oxide Synthase Inhibition by L-NAME Prevents the Decrease of Na+,K+-ATPase Activity in Midbrain of Rats Subjected to Arginine Administration

M. Wajner, C. Dutra-filho, E. Streck, 2001, Neurochemical Research.

Antioxidant treatment strategies for hyperphenylalaninemia

G. Karikas, C. Dutra-filho, K. Schulpis, 2013, Metabolic Brain Disease.

GM1 ganglioside attenuates convulsions and thiobarbituric acid reactive substances production induced by the intrastriatal injection of methylmalonic acid.

J. Bonini, J. Rocha, C. Dutra-filho, 2003, The international journal of biochemistry & cell biology.

Ascorbic acid prevents water maze behavioral deficits caused by early postnatal methylmalonic acid administration in the rat

M. Wajner, A. Wyse, C. Dutra-filho, 2003, Brain Research.

Inhibition of succinate dehydrogenase and β-hydroxybutyrate dehydrogenase activities by methylmalonate in brain and liver of developing rats

M. Wajner, C. Dutra-filho, C. Wannmacher, 1993, Journal of Inherited Metabolic Disease.

Glutaric acid induces oxidative stress in brain of young rats

M. Wajner, A. Wyse, C. Dutra-filho, 2003, Brain Research.

Glutaric acid moderately compromises energy metabolism in rat brain

C. Vargas, M. Wajner, A. Wyse, 2005, International Journal of Developmental Neuroscience.

N-acetylaspartic acid impairs enzymatic antioxidant defenses and enhances hydrogen peroxide concentration in rat brain

M. Wajner, A. Wyse, C. Dutra-filho, 2010, Metabolic Brain Disease.

d-Serine administration provokes lipid oxidation and decreases the antioxidant defenses in rat striatum

G. Leipnitz, M. Wajner, C. Fernandes, 2010, International Journal of Developmental Neuroscience.

Regular exercise prevents oxidative stress in the brain of hyperphenylalaninemic rats

C. Dutra-filho, C. Mescka, G. Dalazen, 2011, Metabolic Brain Disease.

Inhibition of cytochrome c oxidase activity in rat cerebral cortex and human skeletal muscle by D-2-hydroxyglutaric acid in vitro.

G. Leipnitz, M. Wajner, C. Ribeiro, 2002, Biochimica et biophysica acta.

Inhibition of the Mitochondrial Respiratory Chain by Alanine in Rat Cerebral Cortex

M. Wajner, A. Wyse, L. Feksa, 2002, Metabolic Brain Disease.

ANTIOXIDANT ACTIVITY IN SOUTHERN BRAZIL HYPERICUM SPECIES

E. Lissi, C. Dutra-filho, A. Aspée, 2008 .

Homocysteine induces oxidative stress, inflammatory infiltration, fibrosis and reduces glycogen/glycoprotein content in liver of rats

C. Matté, A. Wyse, F. Stefanello, 2009, International Journal of Developmental Neuroscience.

Acute exercise in treated phenylketonuria patients: Physical activity and biochemical response

T. Derks, B. C. Teixeira, C. Dutra-filho, 2015, Molecular genetics and metabolism reports.

Phenylalanine induces oxidative stress and decreases the viability of rat astrocytes: possible relevance for the pathophysiology of neurodegeneration in phenylketonuria

I. J. Bristot, J. Moreira, C. Dutra-filho, 2016, Metabolic Brain Disease.

Effect of histidine administration to female rats during pregnancy and lactation on enzymes activity of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring

C. Dutra-filho, C. Wannmacher, D. Rojas, 2012, Metabolic Brain Disease.

Neurochemical Evidence that the Metabolites Accumulating in 3-Methylcrotonyl-CoA Carboxylase Deficiency Induce Oxidative Damage in Cerebral Cortex of Young Rats

G. Leipnitz, M. Wajner, M. Grings, 2012, Cellular and Molecular Neurobiology.

Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats

G. Leipnitz, M. Wajner, A. Wyse, 2005, International Journal of Developmental Neuroscience.

Ammonia potentiates methylmalonic acid-induced convulsions and TBARS production

K. C. Mann, J. Bonini, C. Dutra-filho, 2003, Experimental Neurology.

Voluntary Exercise Prevents Oxidative Stress in the Brain of Phenylketonuria Mice.

C. Dutra-filho, F. V. van Spronsen, K. Anjema, 2015, JIMD reports.

Administration of Histidine to Female Rats Induces Changes in Oxidative Status in Cortex and Hippocampus of the Offspring

C. Dutra-filho, C. Wannmacher, D. Rojas, 2012, Neurochemical Research.

Effects of histidine and imidazolelactic acid on various parameters of the oxidative stress in cerebral cortex of young rats

M. Wajner, A. Belló-Klein, A. Wyse, 2004, International Journal of Developmental Neuroscience.

Reduced locomotor activity of rats made histidinemic by injection of histidine.

M. Wajner, C. Dutra-filho, C. Wannmacher, 1989, The Journal of nutrition.

Investigation of inflammatory profile in MSUD patients: benefit of L-carnitine supplementation

C. Vargas, M. Wajner, B. Donida, 2015, Metabolic Brain Disease.

Neonatal hyperglycemia induces cell death in the rat brain

C. Dutra-filho, C. Mescka, R. Teixeira, 2017, Metabolic brain disease.

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

C. Vargas, M. Wajner, C. Dutra-filho, 2015 .

Chemically induced acute model of sarcosinemia in wistar rats

C. Dutra-filho, C. Wannmacher, T. Gemelli, 2015, Metabolic brain disease.

Voluntary Exercise Prevents Oxidative Stress in the Brain of Phenylketonuria Mice.

C. Dutra-filho, F. V. van Spronsen, Vibeke M. Bruinenberg, 2015, JIMD reports.

Chronic Exposure to β-Alanine Generates Oxidative Stress and Alters Energy Metabolism in Cerebral Cortex and Cerebellum of Wistar Rats

M. Wajner, C. Dutra-filho, C. Wannmacher, 2017, Molecular Neurobiology.

Inhibition of Rat Brain Lipid Synthesis In Vitro by 4-Hydroxybutyric Acid

M. Wajner, C. Ruschel, C. Dutra-filho, 1999, Metabolic Brain Disease.

Inhibition of brain energy metabolism by the α-keto acids accumulating in maple syrup urine disease

M. Wajner, C. Ribeiro, A. Wyse, 2003 .

In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease

C. Dutra-filho, C. Mescka, G. Dalazen, 2011, Metabolic Brain Disease.