T. Kohyama

发表

Synergistic neutrophil elastase-cytokine interaction degrades collagen in three-dimensional culture.

S. Rennard, C. Sköld, J. Spurzem, 2001, American journal of physiology. Lung cellular and molecular physiology.

Retinoic acid attenuates cytokine-driven fibroblast degradation of extracellular matrix in three-dimensional culture.

D. Romberger, S. Rennard, J. Spurzem, 2001, American journal of respiratory cell and molecular biology.

Size-structured tree populations in gap-dynamic forest-the forest architecture hypothesis for the stable coexistence of species

T. Kohyama, Tadashi Kohyama, 1993 .

Cytokine inhibition of fibroblast-induced gel contraction is mediated by PGE(2) and NO acting through separate parallel pathways.

D. Romberger, S. Rennard, J. Spurzem, 2001, American journal of respiratory cell and molecular biology.

Fibroblasts and monocyte macrophages contract and degrade three-dimensional collagen gels in extended co-culture

S. Rennard, C. Sköld, T. Kohyama, 2001, Respiratory research.

Please address correspondence to:

S. Rennard, S. Abe, Tetsu Kobayashi, 2001 .

Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer

Hiroshi I. Suzuki, Y. Yamaguchi, T. Kohyama, 2014, BMC Cancer.

Cigarette smoke extract inhibits chemotaxis and collagen gel contraction mediated by human bone marrow osteoprogenitor cells and osteoblast-like cells

S. Rennard, S. Abe, Tetsu Kobayashi, 2003, Osteoporosis International.

A phase II study of S-1 and cisplatin with concurrent thoracic radiotherapy followed by durvalumab for unresectable, locally advanced non-small-cell lung cancer in Japan (SAMURAI study)

S. Kusumoto, K. Shiraishi, K. Kaira, 2021, Therapeutic advances in medical oncology.

Tumor necrosis factor superfamily member LIGHT induces epithelial-mesenchymal transition in A549 human alveolar epithelial cells.

T. Jo, T. Kohyama, Y. Yamauchi, 2012, Biochemical and biophysical research communications.

Contributes to Airway Epithelial Injury and Repair Activation of Calcitonin Gene-Related Peptide Receptor during Ozone Inhalation

S. Rennard, D. Hyde, J. Harkema, 2015 .

The effects of oxidative stress induced by prolonged low-dose diesel exhaust particle exposure on the generation of allergic airway inflammation differ between BALB/c and C57BL/6 mice

S. Kudoh, T. Kawada, I. Sugawara, 2009, Immunopharmacology and immunotoxicology.

Collaborative interactions between neutrophil elastase and metalloproteinases in extracellular matrix degradation in three-dimensional collagen gels

S. Rennard, C. Sköld, T. Kohyama, 2001, Respiratory research.

Cigarette Smoke Stimulates MMP‐1 Production by Human Lung Fibroblasts Through the ERK1/2 Pathway

S. Rennard, S. Abe, Tetsu Kobayashi, 2004, COPD.

Pulmonary Apical Opacities on Thin-Section Computed Tomography: Relationship to Primary Spontaneous Pneumothorax in Young Male Patients and Corresponding Histopathologic Findings

T. Okumura, T. Kohyama, M. Kawamoto, 2017, Journal of computer assisted tomography.

PGD(2) modulates fibroblast-mediated native collagen gel contraction.

S. Rennard, T. Wyatt, Tetsu Kobayashi, 2002, American journal of respiratory cell and molecular biology.

Thrombin and TNF-alpha/IL-1beta synergistically induce fibroblast-mediated collagen gel degradation.

S. Rennard, S. Abe, Tetsu Kobayashi, 2006, American journal of respiratory cell and molecular biology.

The effect of cigarette smoke on fibroblast-mediated gel contraction is dependent on cell density

D. Romberger, S. Rennard, J. Spurzem, 2002 .

Simultaneous Stimulation with TGF-β1 and TNF-α Induces Epithelial Mesenchymal Transition in Bronchial Epithelial Cells

T. Kohyama, Y. Yamauchi, T. Nagase, 2010, International Archives of Allergy and Immunology.

Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells.

T. Kohyama, Koji Ito, K. Ito, 1997, American journal of respiratory and critical care medicine.

Cigarette smoke inhibits human bronchial epithelial cell repair processes.

D. Romberger, S. Rennard, C. Sköld, 2001, American journal of respiratory cell and molecular biology.

Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke.

D. Romberger, W. MacNee, S. Rennard, 2002, American journal of physiology. Lung cellular and molecular physiology.

PDE4 inhibitors attenuate fibroblast chemotaxis and contraction of native collagen gels.

S. Rennard, Hui Jung Kim, T. Kohyama, 2002, American journal of respiratory cell and molecular biology.

Glucocorticoids and TGF-β1 Synergize in Augmenting Fibroblast Mediated Contraction of Collagen Gels

S. Rennard, C. Sköld, T. Kohyama, 2001, Inflammation.

Reversible cigarette smoke extract-induced DNA damage in human lung fibroblasts.

S. Rennard, P. Bitterman, S. Abe, 2004, American journal of respiratory cell and molecular biology.

Procaterol Inhibits Lung Fibroblast Migration

T. Kohyama, Y. Yamauchi, T. Nagase, 2009, Inflammation.

Interactions between monocytes and smooth-muscle cells can lead to extracellular matrix degradation.

S. Rennard, C. Sköld, Y. Zhu, 2001, The Journal of allergy and clinical immunology.

Leukotriene D4 potentiates fibronectin-induced migration of human lung fibroblasts.

S. Rennard, Jun Kato, T. Kohyama, 2005, Clinical immunology.

Prostacyclin analogs inhibit fibroblast migration.

S. Rennard, Tetsu Kobayashi, Hui Jung Kim, 2002, American journal of physiology. Lung cellular and molecular physiology.

Prostaglandin E(2) inhibits fibroblast chemotaxis.

D. Romberger, S. Rennard, L. Allegra, 2001, American journal of physiology. Lung cellular and molecular physiology.

Thrombin and TNF-α/IL-1β Synergistically Induce Fibroblast-Mediated Collagen Gel Degradation

S. Rennard, S. Abe, Tetsu Kobayashi, 2006 .

A potent immunosuppressant FK506 inhibits IL-8 expression in human eosinophils.

T. Kohyama, K. Ito, H. Takizawa, 1999, Molecular cell biology research communications : MCBRC.

Lymphotoxin β Receptor Signaling Induces IL-8 Production in Human Bronchial Epithelial Cells

T. Jo, T. Kohyama, Y. Yamauchi, 2014, PloS one.

Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells.

D. Romberger, S. Rennard, Hui Jung Kim, 2002, American journal of physiology. Lung cellular and molecular physiology.

Clarithromycin inhibits fibroblast migration.

Jun Kato, T. Kohyama, Y. Yamauchi, 2008, Respiratory medicine.

Cytokines modulate cilomilast response in lung fibroblasts.

S. Rennard, S. Abe, Tetsu Kobayashi, 2004, Clinical immunology.

Persistence of TGF-β1 induction of increased fibroblast contractility

D. Romberger, S. Rennard, J. Spurzem, 2007, In Vitro Cellular & Developmental Biology - Animal.

Persistence of TGF-β1 induction of increased fibroblast contractility

D. Romberger, S. Rennard, J. Spurzem, 2001, In Vitro Cellular & Developmental Biology - Animal.

Fourteen-Member Macrolides Inhibit Interleukin-8 Release by Human Eosinophils from Atopic Donors

Makoto Sato, T. Kohyama, Koji Ito, 1999, Antimicrobial Agents and Chemotherapy.

Eosinophils from Atopic Donors Interleukin-8 Release by Human Fourteen-Member Macrolides Inhibit

Makoto Sato, T. Kohyama, Koji Ito, 1999 .

A novel antiallergic drug epinastine inhibits IL-8 release from human eosinophils.

T. Kohyama, K. Ito, H. Takizawa, 1997, Biochemical and biophysical research communications.

Methotrexate induces interleukin-8 production by human bronchial and alveolar epithelial cells.

Kazuhiko Yamamoto, T. Kohyama, Y. Yamauchi, 2004, Clinical science.

Histamine stimulates human lung fibroblast migration

T. Kohyama, Y. Yamauchi, T. Nagase, 2010, Molecular and Cellular Biochemistry.

IL-4 and IL-13 Induce Chemotaxis of Human Foreskin Fibroblasts, But Not Human Fetal Lung Fibroblasts

S. Rennard, S. Abe, Tetsu Kobayashi, 2004, Inflammation.

Potentiation of human lung fibroblast chemotaxis by the thromboxane A(2) analog U-46619.

H. J. Kim, S. Rennard, X. Liu, 2002, The Journal of laboratory and clinical medicine.

Non-infectious bronchiolitis as an early pulmonary complication of hematopoietic stem cell transplantation.

D. Takai, Y. Kanda, H. Kitagawa, 2008, Internal medicine.

Eosinophil adhesion to human bronchial epithelial cells: regulation by cytokines.

S. Tohma, T. Kohyama, K. Ito, 1997, International archives of allergy and immunology.

[Outcome in patients with interstitial lung disease and polymyositis-dermatomyositis--a subgroup with poor prognosis].

T. Kohyama, T. Yanagawa, H. Okazaki, 1996, Nihon Kyobu Shikkan Gakkai zasshi.

Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells.

M. Yanagisawa, T. Kohyama, K. Ito, 1998, The European respiratory journal.

Roxithromycin Inhibits Cytokine Production by and Neutrophil Attachment to Human Bronchial Epithelial Cells In Vitro

Kazuhiko Yamamoto, Kazuo Kobayashi, T. Kohyama, 1998, Antimicrobial Agents and Chemotherapy.

Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice.

S. Kudoh, Satoru Takahashi, Masayuki Yamamoto, 2008, Clinical immunology.

Hemoglobin Kansas as a Rare Cause of Cyanosis: A Case Report and Review of the Literature

Minoru Yoshida, T. Kohyama, K. Matsui, 2017, Internal medicine.

[Importance of interstitial lung disease in collagen vascular disease: analysis of outcome].

T. Kohyama, T. Yanagawa, H. Okazaki, 1996, Nihon Kyobu Shikkan Gakkai zasshi.

Interleukin-4- and interleukin-13-enhanced transforming growth factor-beta2 production in cultured human bronchial epithelial cells is attenuated by interferon-gamma.

S. Rennard, S. Abe, J. Spurzem, 2002, American journal of respiratory cell and molecular biology.

Glucocorticoids modulate TGF-beta production by human fetal lung fibroblasts.

D. Romberger, S. Rennard, C. Sköld, 2003, Inflammation.

A phase II study of S-1 and cisplatin with concurrent thoracic radiotherapy followed by durvalumab for unresectable, locally advanced non-small-cell lung cancer in Japan (SAMURAI study): primary analysis

Y. Fukuda, K. Shiraishi, K. Kaira, 2022, Therapeutic advances in medical oncology.

Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor

J. Nakajima, T. Jo, T. Kohyama, 2014, Experimental lung research.

Nerve growth factor stimulates fibronectin-induced fibroblast migration.

S. Rennard, S. Abe, Tetsu Kobayashi, 2002, The Journal of laboratory and clinical medicine.

Glucocorticoids Modulate TGF-β Production

D. Romberger, S. Rennard, C. Sköld, 2002, Inflammation.

Characterization of human lung cancer-associated fibroblasts in three-dimensional in vitro co-culture model.

J. Nakajima, T. Kohyama, Y. Morishita, 2012, Biochemical and biophysical research communications.

Thrombin induces collagen gel contraction partially through PAR1 activation and PKC-ϵ

S. Rennard, M. Hashimoto, S. Abe, 2004, European Respiratory Journal.

Tumor necrosis factor-α enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-β1

Jun Kato, T. Kohyama, Y. Yamauchi, 2010, Experimental lung research.

Smad3 mediates TGF-beta1 induction of VEGF production in lung fibroblasts.

S. Rennard, M. Hashimoto, S. Abe, 2005, Biochemical and biophysical research communications.

Glucocorticoids Modulate TGF-β Production by Human Fetal Lung Fibroblasts

D. Romberger, S. Rennard, C. Sköld, 2003, Inflammation.

Phosphodiesterase 4 inhibitor cilomilast inhibits fibroblast-mediated collagen gel degradation induced by tumor necrosis factor-alpha and neutrophil elastase.

S. Rennard, Tetsu Kobayashi, T. Kohyama, 2002, American journal of respiratory cell and molecular biology.

Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels.

S. Rennard, S. Abe, R. Senior, 2014, American journal of physiology. Lung cellular and molecular physiology.

Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.

Kohei Miyazono, K. Miyazono, T. Watabe, 2009, Cancer research.

Diesel exhaust particles induce NF-kappa B activation in human bronchial epithelial cells in vitro: importance in cytokine transcription.

S. Kudoh, K. Matsushima, T. Kohyama, 1999, Journal of immunology.

Diesel exhaust particles upregulate eotaxin gene expression in human bronchial epithelial cells via nuclear factor-kappa B-dependent pathway.

S. Kudoh, K. Matsushima, Yoshinobu Saito, 2003, American journal of physiology. Lung cellular and molecular physiology.

Using the nudge method to promote referrals of HBs antigen-/HCV antibody-positive patients from non-hepatology specialty physicians

M. Hara, K. Kikuchi, T. Kohyama, 2022, Kanzo.

Prostaglandin D2 inhibits fibroblast migration

S. Rennard, T. Kohyama, F. Wen, 2002, European Respiratory Journal.

Serum Reactive Oxygen Metabolite Levels Predict Severe Exacerbations of Asthma

T. Kohyama, H. Wada, Y. Yamauchi, 2016, PloS one.

Questionnaire for diagnosing asthma-COPD overlap in COPD: Development of ACO screening questionnaire (ACO-Q).

T. Kohyama, H. Nagase, Hikaru Toyota, 2023, Allergology international : official journal of the Japanese Society of Allergology.

Nrf2 is closely related to allergic airway inflammatory responses induced by low-dose diesel exhaust particles in mice.

S. Kudoh, Satoru Takahashi, Masayuki Yamamoto, 2010, Clinical immunology.

AIRWAY INFLAMMATORY RESPONSES TO OXIDATIVE STRESS INDUCED BY PROLONGED LOW-DOSE DIESEL EXHAUST PARTICLE EXPOSURE FROM BIRTH DIFFER BETWEEN MOUSE BALB/C AND C57BL/6 STRAINS

S. Kudoh, T. Kawada, I. Sugawara, 2008, Experimental lung research.

Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells

T. Jo, T. Kohyama, Y. Yamauchi, 2015, PloS one.

Glucocorticoids modulate TGF-beta production.

D. Romberger, S. Rennard, C. Sköld, 2002, Inflammation.

C-REACTIVE PROTEIN MODULATES HUMAN LUNG FIBROBLAST MIGRATION

S. Rennard, Jun Kato, T. Kohyama, 2009, Experimental lung research.

Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts.

S. Rennard, M. Hashimoto, K. Kamio, 2006, Biochemical and biophysical research communications.

TGF-β1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels

S. Rennard, P. Bitterman, S. Abe, 2005, Respiratory research.

Dynamic change in respiratory resistance during inspiratory and expiratory phases of tidal breathing in patients with chronic obstructive pulmonary disease

Taisuke Jo, T. Jo, T. Kohyama, 2012, International journal of chronic obstructive pulmonary disease.

Interferon-γ Inhibits Transforming Growth Factor-β Production in Human Airway Epithelial Cells by Targeting Smads

S. Rennard, S. Abe, Tetsu Kobayashi, 2004 .

Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads.

S. Rennard, S. Abe, Tetsu Kobayashi, 2004, American Journal of Respiratory Cell and Molecular Biology.

Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer

Hiroshi I. Suzuki, Y. Yamaguchi, T. Kohyama, 2014, BMC Cancer.

Ultrafine carbon black particles inhibit human lung fibroblast-mediated collagen gel contraction.

D. Romberger, W. MacNee, S. Rennard, 2003, American journal of respiratory cell and molecular biology.

The anti-inflammatory effects of macrolides

M. Woodhead, T. Kohyama, T. Ohtoshi, 1999, Thorax.

Thrombin and TNF-α/IL-1β Synergistically Induce Fibroblast-Mediated Collagen Gel Degradation

S. Rennard, S. Abe, Tetsu Kobayashi, 2006 .

Thrombin and TNF-α/IL-1β Synergistically Induce Fibroblast-Mediated Collagen Gel Degradation

S. Rennard, S. Abe, Tetsu Kobayashi, 2006 .

Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.

K. Miyazono, T. Watabe, T. Kohyama, 2009, Cancer research.

The effect of cigarette smoke on fibroblast-mediated gel contraction is dependent on cell density

D. Romberger, S. Rennard, J. Spurzem, 2002 .

Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells.

D. Romberger, S. Rennard, T. Kohyama, 2002, American journal of physiology. Lung cellular and molecular physiology.