D. Nelson

发表

Effect of ozone exposure on alveolar macrophage-mediated immunosuppressive activity in rats.

P. Holt, E. Koike, T. Kobayashi, 1998, Toxicological sciences : an official journal of the Society of Toxicology.

Tumor growth or regression: powered by inflammation

D. Nelson, R. Ganss, 2006, Journal of leukocyte biology.

The Use of Agonistic Anti-CD40 Therapy in Treatments for Cancer

A. Nowak, B. Robinson, R. Lake, 2012, International reviews of immunology.

Photophysical and biological investigation of phenol substituted rhenium tetrazolato complexes.

K. Gordon, B. Skelton, D. Nelson, 2019, Dalton transactions.

Modulation of airway intraepithelial dendritic cells following exposure to steroids.

P. Holt, D. Nelson, A. McWilliam, 1995, American journal of respiratory and critical care medicine.

Defective regional immunity in the respiratory tract of neonates is attributable to hyporesponsiveness of local dendritic cells to activation signals.

P. Holt, D. Nelson, Patrick G. Holt, 1995, Journal of immunology.

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

S. Dhaliwal, D. Nelson, C. Jackaman, 2015, Immunity & Ageing.

Targeting macrophages rescues age‐related immune deficiencies in C57BL/6J geriatric mice

M. Grounds, T. Shavlakadze, Z. Soffe, 2013, Aging cell.

CD40‐activated B cells contribute to mesothelioma tumor regression

S. Cornwall, D. Nelson, C. Jackaman, 2011, Immunology and cell biology.

Mesothelioma Tumor Cells Modulate Dendritic Cell Lipid Content, Phenotype and Function

C. Mamotte, D. Nelson, C. Jackaman, 2015, PloS one.

Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells

S. Cornwall, A. Lew, B. Robinson, 2009, European Respiratory Journal.

IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice

D. Nelson, D. Dye, C. Jackaman, 2014, AGE.

Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?

D. Nelson, C. Jackaman, 2014, Experimental Gerontology.

Tumor antigens are constitutively presented in the draining lymph nodes.

D. Lo, L. Sherman, B. Robinson, 1999, Journal of immunology.

Microenvironment-Dependent Gradient of CTL Exhaustion in the AE17sOVA Murine Mesothelioma Tumor Model

J. Aerts, L. Bradley, P. Katsikis, 2020, Frontiers in Immunology.

''Arming'' of Tumor Antigen-Specific CTL Antigen Cross-Presentation and Effective Tumor Progression Despite Efficient Tumor

S. Mukherjee, D. Nelson, C. Bundell, 2017 .

Tumor Progression Despite Efficient Tumor Antigen Cross-Presentation and Effective “Arming” of Tumor Antigen-Specific CTL1

S. Mukherjee, D. Nelson, C. Bundell, 2001, The Journal of Immunology.

Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomes

A. Musk, S. Cornwall, A. Nowak, 2016, Oncoimmunology.

Aging and cancer: The role of macrophages and neutrophils

P. Metharom, F. Pixley, D. Nelson, 2017, Ageing Research Reviews.

Vasculature: A Novel Mechanism for IL-2 Tumor Cells and Tumor-Associated T Cells That Mediate Destruction of + CD8IL-2 Intratumoral Immunotherapy Enhances

B. Robinson, D. Nelson, C. Jackaman, 2003 .

IL-2 Intratumoral Immunotherapy Enhances CD8+ T Cells That Mediate Destruction of Tumor Cells and Tumor-Associated Vasculature: A Novel Mechanism for IL-2 1

B. Robinson, D. Nelson, C. Jackaman, 2003, The Journal of Immunology.

Gene therapy of mesothelioma

R. G. van der Most, B. Robinson, D. Nelson, 2005, Expert opinion on biological therapy.

Intratumoral Poly-N-Acetyl Glucosamine-Based Polymer Matrix Provokes a Prolonged Local Inflammatory Response That, When Combined with IL-2, Induces Regression of Malignant Mesothelioma in a Murine Model

B. Robinson, D. Nelson, A. Currie, 2005, Journal of immunotherapy.

Immunoregulation of asthma: control of T-lymphocyte activation in the respiratory tract.

P. Holt, P. McMenamin, B. Holt, 1991, The European respiratory journal. Supplement.

IL-2/CD40-driven NK cells install and maintain potency in the anti-mesothelioma effector/memory phase.

B. Robinson, D. Nelson, C. Jackaman, 2012, International immunology.

Dendritic cells infected with a vaccinia virus interleukin-2 vector secrete high levels of IL-2 and can become efficient antigen presenting cells that secrete high levels of the immunostimulatory cytokine IL-12

S. Mukherjee, J. Upham, B. Robinson, 2003, Cancer Gene Therapy.

Regulation of Antigen Presentation in the Lung and Airways: The Central Role of Class II MHC-Bearing Dendritic Cells

S. McWilliam, P. Holt, D. Nelson, 1997 .

Development of the airway intraepithelial dendritic cell network in the rat from class II major histocompatibility (Ia)-negative precursors: differential regulation of Ia expression at different levels of the respiratory tract

P. Holt, D. Nelson, A. McWilliam, 1994, The Journal of experimental medicine.

Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses

D. Nelson, C. Jackaman, 2012, Cancer Immunology, Immunotherapy.

Th-1/Th-2 switch regulation in immune responses to inhaled antigens. Role of dendritic cells in the aetiology of allergic respiratory disease.

P. Holt, D. Nelson, A. McWilliam, 1997, Advances in experimental medicine and biology.

Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

M. Grounds, F. Pixley, D. Nelson, 2018, Front. Genet..

Cross‐presentation of tumour antigens: Evaluation of threshold, duration, distribution and regulation

B. Robinson, R. Lake, D. Nelson, 1999, Immunology and cell biology.

Aging Leads to Increased Monocytes and Macrophages With Altered CSF-1 Receptor Expression and Earlier Tumor-Associated Macrophage Expansion in Murine Mesothelioma

F. Pixley, D. Nelson, L. Duong, 2022, Frontiers in Aging.

Murine mesothelioma induces locally-proliferating IL-10+TNF-α+CD206−CX3CR1+ M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy

D. Nelson, C. Jackaman, Joanne K Gardner, 2016, Oncoimmunology.

Role of dendritic cells, macrophages, and gamma delta T cells in antigen processing and presentation in the respiratory mucosa

P. Holt, J. Upham, D. Nelson, 1996 .

Rapid Copper Acquisition by Developing Murine Mesothelioma: Decreasing Bioavailable Copper Slows Tumor Growth, Normalizes Vessels and Promotes T Cell Infiltration

D. Nelson, C. Jackaman, A. Crowe, 2013, PloS one.

Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T‐ and B‐cell zones

M. Grounds, T. Shavlakadze, P. Metharom, 2018, Immunology and cell biology.

Lack of ignorance to tumor antigens: evaluation using nominal antigen transfection and T-cell receptor transgenic lymphocytes in Lyons-Parish analysis--implications for tumor tolerance.

B. Robinson, R. Lake, D. Nelson, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

The biology of airway dendritic cells

P. Holt, D. Nelson, A. McWilliam, 1995, Immunology and cell biology.

Cytokine-armed vaccinia virus infects the mesothelioma tumor microenvironment to overcome immune tolerance and mediate tumor resolution

D. Nelson, C. Jackaman, 2010, Cancer Gene Therapy.

Sarcostemma viminale activates macrophages to a pro-inflammatory phenotype

D. Nelson, C. Jackaman, B. Brestovac, 2015, Comparative Clinical Pathology.

Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces

P. Holt, D. Nelson, A. McWilliam, 1994, The Journal of experimental medicine.

Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules

C. Mamotte, D. Nelson, C. Jackaman, 2017, Ageing Research Reviews.

Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice.

G. Hämmerling, J. Hamzah, B. Arnold, 2008, The Journal of clinical investigation.

Gene therapy for malignant mesothelioma: beyond the infant years

B. Robinson, D. Nelson, R. V. D. Most, 2006, Cancer Gene Therapy.

In Vivo Cross-Presentation of a Soluble Protein Antigen: Kinetics, Distribution, and Generation of Effector CTL Recognizing Dominant and Subdominant Epitopes1

D. Nelson, C. Bundell, B. Robinson, 2000, The Journal of Immunology.

Brief Definitive Report Dendritic Cells Are Recruited into the Airway Epithelium during the Inflammatory Response to a Broad Spectrum of Stimuli

P. Holt, D. Nelson, A. McWilliam, 2022 .

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

S. Dhaliwal, D. Nelson, C. Jackaman, 2015, Immunity & Ageing.

The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy

C. Mamotte, D. Nelson, C. Jackaman, 2018, Front. Med..

Functional endogenous cytotoxic T lymphocytes are generated to multiple antigens co-expressed by progressing tumors; after intra-tumoral IL-2 therapy these effector cells eradicate established tumors

A. Suhrbier, B. Robinson, D. Nelson, 2006, Cancer Immunology, Immunotherapy.

The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor

L. Palmer, S. Mukherjee, B. Robinson, 2001, Cancer Gene Therapy.

A review of the importance of immune responses in luminal B breast cancer

A. Chan, K. Munyard, D. Nelson, 2017, Oncoimmunology.

Lipid-laden partially-activated plasmacytoid and CD4−CD8α+ dendritic cells accumulate in tissues in elderly mice

C. Mamotte, D. Nelson, C. Jackaman, 2014, Immunity & Ageing.

Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways.

P. Holt, D. Nelson, J. Sedgwick, 1994, Journal of immunology.

Developing a translational murine‐to‐canine pathway for an IL‐2/agonist anti‐CD40 antibody cancer immunotherapy

D. Nelson, K. Wyatt, J. Jardine, 2022, Veterinary and comparative oncology.

Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8+ T cells in vivo

A. Nowak, D. Nelson, C. Jackaman, 2012, Cancer Immunology, Immunotherapy.

Dominant and Subdominant Epitopes Generation of Effector CTL Recognizing Protein Antigen: Kinetics, Distribution, and In Vivo Cross-Presentation of a Soluble

D. Nelson, C. Bundell, B. Robinson, 2000 .

Experimental models: mesothelioma

B. Robinson, D. Nelson, B. Robinson, 2008 .

Gender balance in patients with systemic lupus erythematosus.

D. Nelson, J. Wetherall, C. Bundell, 2017, Autoimmunity reviews.

CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy

S. Dhaliwal, P. Metharom, D. Nelson, 2019, Oncoimmunology.

The “Trojan Horse” Approach to Tumor Immunotherapy: Targeting the Tumor Microenvironment

B. Robinson, D. Nelson, S. Fisher, 2014, Journal of immunology research.

Turning the tumor microenvironment into a self vaccine site

D. Nelson, 2012, Oncoimmunology.

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.

A. Lew, B. Robinson, D. Nelson, 2008, International immunology.

Selective attrition of non-recirculating T cells during normal passage through the lung vascular bed.

P. Holt, D. Nelson, D. Strickland, 1990, Immunology.

Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation

A. Musk, C. Mamotte, S. Cornwall, 2018, PloS one.

Prognostic role of immune environment in luminal B early breast cancer

A. Chan, D. Nelson, H. Chih, 2023, Cancer medicine.

IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice

D. Nelson, D. Dye, C. Jackaman, 2014, AGE.

Allergen presentation in the airways

P. Holt, D. Nelson, A. McWilliam, 1995 .

The STING agonist, DMXAA, reduces tumor vessels and enhances mesothelioma tumor antigen presentation yet blunts cytotoxic T cell function in a murine model

S. Cornwall, A. Nowak, D. Nelson, 2022, Frontiers in Immunology.

Primary sensitisation to inhalant allergens during infancy

P. Holt, D. Nelson, C. Mcmenamin, 1990 .