V. Abrahams

发表

ORIGINAL ARTICLE: Antiphospholipid Antibodies Induce a Pro‐Inflammatory Response in First Trimester Trophoblast Via the TLR4/MyD88 Pathway

J. Brosens, M. Mulla, L. Chamley, 2009, American journal of reproductive immunology.

Research Recommendations From the National Institutes of Health Workshop on Predicting, Preventing, and Treating Preeclampsia

Alison D. Gernand, B. Cox, U. Reddy, 2019, Hypertension.

The role of the Nod-like receptor family in trophoblast innate immune responses.

V. Abrahams, 2011, Journal of reproductive immunology.

TLR6 Modulates First Trimester Trophoblast Responses to Peptidoglycan1

G. Mor, R. Romero, K. Koga, 2008, The Journal of Immunology.

TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer.

R. Chen, G. Mor, D. Silasi, 2006, Cancer research.

Trophoblast Cells as Immune Regulators

G. Mor, V. Abrahams, 2006, Immunology of Pregnancy.

The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy.

G. Mor, V. Abrahams, S. Straszewski-Chavez, 2005, Endocrine reviews.

Divergent Trophoblast Responses to Bacterial Products Mediated by TLRs

R. Romero, T. Chaiworapongsa, V. Abrahams, 2004, The Journal of Immunology.

Interaction of the Estrogen Receptors with the Fas Ligand Promoter in Human Monocytes1

G. Mor, T. Rutherford, V. Abrahams, 2003, The Journal of Immunology.

Nod1 Activation by Bacterial iE-DAP Induces Maternal–Fetal Inflammation and Preterm Labor

E. Norwitz, S. Guller, M. Mulla, 2011, The Journal of Immunology.

Activation of TLR3 in the trophoblast is associated with preterm delivery.

R. Romero, K. Koga, V. Abrahams, 2009, American journal of reproductive immunology.

Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis.

G. Mor, R. Romero, H. Kuivaniemi, 2004, American journal of obstetrics and gynecology.

Is the trophoblast an immune regulator? The role of Toll-like receptors during pregnancy.

G. Mor, R. Romero, V. Abrahams, 2005, Critical reviews in immunology.

Immunology of the Placenta.

M. Tong, V. Abrahams, 2020, Obstetrics and gynecology clinics of North America.

Peptidoglycan Induces Necrosis and Regulates Cytokine Production in Murine Trophoblast Stem Cells

M. Parast, V. Abrahams, Jessica J. Rabenold, 2011, American journal of reproductive immunology.

Interferon‐α and Angiogenic Dysregulation in Pregnant Lupus Patients Who Develop Preeclampsia

Mimi Kim, S. Karumanchi, J. Salmon, 2015, Arthritis & rheumatology.

Antiphospholipid antibody-induced miR-146a-3p drives trophoblast interleukin-8 secretion through activation of Toll-like receptor 8.

J. Brosens, M. Guerra, J. Salmon, 2016, Molecular human reproduction.

Toll‐like Receptor‐Mediated Responses by Placental Hofbauer Cells (HBCs): A Potential Pro‐Inflammatory Role for Fetal M2 Macrophages

G. Krikun, G. Mor, E. Norwitz, 2015, American journal of reproductive immunology.

Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

G. Leone, C. Mineo, P. Shaul, 2021, Circulation research.

Recurrent miscarriage: evidence to accelerate action

O. Christiansen, J. Brosens, A. Coomarasamy, 2021, The Lancet.

Acetaminophen Attenuates invasion and alters the expression of extracellular matrix enzymes and vascular factors in human first trimester trophoblast cells.

V. Vasiliou, S. Guller, S. Whirledge, 2020, Placenta.

Neutrophils in preterm birth: Friend or foe?

M. Tong, V. Abrahams, 2020, Placenta.

Aspirin‐Triggered Lipoxin Prevents Antiphospholipid Antibody Effects on Human Trophoblast Migration and Endothelial Cell Interactions

M. Mulla, L. Chamley, V. Abrahams, 2015, Arthritis & rheumatology.

Zika virus productively infects primary human placenta-specific macrophages.

B. Lindenbach, E. Fikrig, Ryuta Uraki, 2016, JCI insight.

Inhibition of Human Polymorphonuclear Cell Oxidative Burst by 17‐β‐estradiol and 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin

J. Collins, V. Abrahams, M. Fanger, 2003, American journal of reproductive immunology.

Maternal Influenza A Virus Infection Restricts Fetal and Placental Growth and Adversely Affects the Fetal Thymic Transcriptome

T. R. Hansen, G. Bouma, H. Bielefeldt-Ohmann, 2020, Viruses.

The isolation and characterization of a novel telomerase immortalized first trimester trophoblast cell line, Swan 71.

G. Mor, A. Alvero, S. Guller, 2009, Placenta.

Lipopolysaccharide-Stimulated Human Fetal Membranes Induce Neutrophil Activation and Release of Vital Neutrophil Extracellular Traps

G. Mor, M. Tong, V. Abrahams, 2019, The Journal of Immunology.

Mechanisms of antiphospholipid antibody-associated pregnancy complications.

V. Abrahams, 2009, Thrombosis research.

The Immunology of Pregnancy

G. Mor, V. Abrahams, 2009 .

Zika virus infection of Hofbauer cells

E. Fikrig, S. Guller, K. Jurado, 2017, American journal of reproductive immunology.

Antiphospholipid Antibodies From Women With Pregnancy Morbidity and Vascular Thrombosis Induce Endothelial Mitochondrial Dysfunction, mTOR Activation, and Autophagy

V. Abrahams, Carolina Rúa, M. Viana, 2021, Frontiers in Physiology.

Vimentin is a dominant target of in situ humoral immunity in human lupus tubulointerstitial nephritis

A. Dyer, R. Ness, K. Sutton-Tyrrell, 2014, Arthritis Research & Therapy.

AKT Controls Human First Trimester Trophoblast Cell Sensitivity to FAS-Mediated Apoptosis by Regulating XIAP Expression1

G. Mor, V. Abrahams, R. Romero, 2010, Biology of reproduction.

Chlamydia trachomatis Infection Increases Fallopian Tube PROKR2 via TLR2 and NFκB Activation Resulting in a Microenvironment Predisposed to Ectopic Pregnancy

Kai-Fai Lee, H. Jabbour, M. Mcclure, 2011, The American journal of pathology.

Role of NOD2 in antiphospholipid antibody-induced and bacterial MDP amplification of trophoblast inflammation.

J. Salmon, M. Mulla, L. Chamley, 2019, Journal of autoimmunity.

Antiphospholipid Antibodies Inhibit Trophoblast Toll‐Like Receptor and Inflammasome Negative Regulators

J. Salmon, M. Mulla, L. Chamley, 2018, Arthritis & rheumatology.

Vitamin D Reverses aPL‐induced Inflammation and LMWH‐induced sFlt‐1 Release by Human Trophoblast

J. Brosens, M. Mulla, L. Chamley, 2015, American journal of reproductive immunology.

Antiphospholipid antibodies limit trophoblast migration by reducing IL‐6 production and STAT3 activity

J. Brosens, M. Mulla, L. Chamley, 2011, American journal of reproductive immunology.

Aspirin and Heparin Effect on Basal and Antiphospholipid Antibody Modulation of Trophoblast Function

J. Brosens, C. Lockwood, M. Mulla, 2011, Obstetrics and gynecology.

Modulation of Trophoblast Angiogenic Factor Secretion by Antiphospholipid Antibodies is Not Reversed by Heparin

J. Brosens, M. Mulla, L. Chamley, 2011, American journal of reproductive immunology.

Induction of tumor necrosis factor α production by adhered human monocytes: A key role for Fcγ receptor type IIIA in rheumatoid arthritis

P. Lydyard, J. Edwards, V. Abrahams, 2000 .

NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells.

G. Mor, S. Guller, V. Abrahams, 2020, Journal of reproductive immunology.

Human fetal membrane IL-1β production in response to bacterial components is mediated by uric-acid induced NLRP3 inflammasome activation.

V. Abrahams, Alex S. Miller, Tiffany N. Hidalgo, 2021, Journal of reproductive immunology.

Uric Acid Induces Trophoblast IL‐1β Production Via the Inflammasome: Implications for the Pathogenesis of Preeclampsia

P. Kavathas, E. Norwitz, S. Guller, 2011, American journal of reproductive immunology.

Magnesium sulfate differentially modulates fetal membrane inflammation in a time‐dependent manner

E. Norwitz, V. Abrahams, S. Cross, 2018, American journal of reproductive immunology.

Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation

M. Tong, S. Guller, V. Abrahams, 2017, The Journal of Immunology.

Single- and double-stranded viral RNA generate distinct cytokine and antiviral responses in human fetal membranes.

E. Norwitz, S. Guller, V. Abrahams, 2014, Molecular human reproduction.

responses in human fetal membranes

E. Norwitz, S. Guller, V. Abrahams, 2014 .

Human Fetal Membranes Generate Distinct Cytokine Profiles in Response to Bacterial Toll-Like Receptor and Nod-Like Receptor Agonists1

E. Norwitz, S. Guller, V. Abrahams, 2014, Biology of reproduction.

Bacterial Modulation of Human Fetal Membrane Toll‐like Receptor Expression

G. Saade, R. Menon, V. Abrahams, 2013, American journal of reproductive immunology.

X-linked inhibitor of apoptosis (XIAP) confers human trophoblast cell resistance to Fas-mediated apoptosis.

G. Mor, E. Funai, V. Abrahams, 2004, Molecular human reproduction.

The Fas/Fas ligand system and cancer

G. Mor, V. Abrahams, M. Kamsteeg, 2003, Molecular biotechnology.

Epithelial ovarian cancer cells secrete functional Fas ligand.

G. Mor, B. Hanczaruk, P. Schwartz, 2003, Cancer research.

The Placental Syncytium and the Pathophysiology of Preeclampsia and Intrauterine Growth Restriction

G. Krikun, G. Mor, Han-Hsuan Fu, 2008, Annals of the New York Academy of Sciences.

Emerging Treatment Models in Rheumatology: Antiphospholipid Syndrome and Pregnancy: Pathogenesis to Translation

J. Salmon, L. Chamley, V. Abrahams, 2017, Arthritis & rheumatology.

Mechanisms of Antiphospholipid Antibody-Mediated Pregnancy Morbidity

C. Mineo, J. Salmon, P. Meroni, 2017 .

The role of anti-phospholipid antibodies in autoimmune reproductive failure.

L. Chamley, V. Abrahams, P. Pantham, 2016, Reproduction.

What is the Mechanism(s) of Antiphospholipid Antibody-Mediated Pregnancy Morbidity?

A. Tincani, J. Salmon, P. Meroni, 2012 .

Immunological effects of placental extracellular vesicles

M. Tong, L. Chamley, V. Abrahams, 2018, Immunology and cell biology.

ORIGINAL ARTICLE: Regulation of Nod1 and Nod2 in First Trimester Trophoblast Cells

S. Guller, M. Mulla, B. Panda, 2009, American journal of reproductive immunology.

NOD Protein Expression and Function in First Trimester Trophoblast Cells

Shawna K. Joyce, V. Abrahams, M. Costello, 2007, American journal of reproductive immunology.

Polymicrobial stimulation of human fetal membranes induce neutrophil activation and neutrophil extracellular trap release.

M. Tong, V. Abrahams, S. Hanna, 2021, Journal of reproductive immunology.

Activated Neutrophils Propagate Fetal Membrane Inflammation and Weakening through ERK and Neutrophil Extracellular Trap–Induced TLR-9 Signaling

M. Tong, V. Abrahams, A. H. Smith, 2021, The Journal of Immunology.

Utero-placental haemodynamics in the pathogenesis of pre-eclampsia.

I. Crocker, C. Sibley, P. Baker, 2009, Placenta.

Macrophages and Apoptotic Cell Clearance During Pregnancy

G. Mor, R. Romero, V. Abrahams, 2004, American journal of reproductive immunology.

Distinct non‐coding RNA cargo of extracellular vesicles from M1 and M2 human primary macrophages

V. Abrahams, M. Venø, P. Pantazi, 2022, bioRxiv.

Trophoblast–Macrophage Interactions: a Regulatory Network for the Protection of Pregnancy

G. Mor, R. Romero, A. Alvero, 2007, American journal of reproductive immunology.

First trimester trophoblast cells secrete Fas ligand which induces immune cell apoptosis.

G. Mor, S. Guller, V. Abrahams, 2004, Molecular human reproduction.

Focal Increases of Fetal Macrophages in Placentas from Pregnancies with Histological Chorioamnionitis: Potential Role of Fibroblast Monocyte Chemotactic Protein‐1

G. Krikun, G. Mor, C. Lockwood, 2011, American journal of reproductive immunology.

Heparin prevents programmed cell death in human trophoblast.

Julia M. Francis, E. Lam, J. Brosens, 2006, Molecular human reproduction.

Heightened Pro-Inflammatory Effect of Preeclamptic Placental Microvesicles on Peripheral Blood Immune Cells in Humans1

V. Abrahams, J. Aplin, Carolyn J.P. Jones, 2012, Biology of reproduction.

A Role for Uric Acid and the Nalp3 Inflammasome in Antiphospholipid Antibody-Induced IL-1β Production by Human First Trimester Trophoblast

J. Brosens, P. Kavathas, J. Salmon, 2013, PloS one.

Immune cell activation by trophoblast‐derived microvesicles is mediated by syncytin 1

M. Mulla, V. Abrahams, J. Aplin, 2012, Immunology.

Human Endometrial Endothelial Cells Generate Distinct Inflammatory and Antiviral Responses to the TLR3 agonist, Poly(I:C) and the TLR8 agonist, viral ssRNA

G. Krikun, V. Abrahams, J. Potter, 2013, American journal of reproductive immunology.

Nod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatis

P. Kavathas, M. Mulla, V. Abrahams, 2012, Mucosal Immunology.

Progesterone Inhibits Apoptosis in Fetal Membranes by Altering Expression of Both Pro- and Antiapoptotic Proteins

S. Ng, E. Norwitz, V. Abrahams, 2018, Reproductive sciences.

Allopurinol inhibits excess glucose-induced trophoblast IL-1b and ROS production.

M. Mulla, V. Abrahams, C. Han, 2019, Reproduction.

Alterations in Syncytiotrophoblast Cytokine Expression Following Treatment with Lipopolysaccharide

G. Mor, S. Guller, V. Abrahams, 2006, American journal of reproductive immunology.

Herpesvirus-infected Hofbauer cells activate endothelial cells through an IL-1β-dependent mechanism.

G. Mor, S. Guller, V. Abrahams, 2020, Placenta.

Cutting‐Edge Report: TLR10 Plays a Role in Mediating Bacterial Peptidoglycan‐Induced Trophoblast Apoptosis

E. Norwitz, S. Guller, M. Mulla, 2013, American journal of reproductive immunology.

Visualization and Quantification of Neutrophil Extracellular Traps.

M. Tong, V. Abrahams, 2020, Methods in molecular biology.

Circulating Cytokines and Alarmins Associated with Placental Inflammation in High-Risk Pregnancies

C. Sibley, S. Allan, A. Heazell, 2014, American journal of reproductive immunology.

Progesterone Inhibits Basal and TNF-α-Induced Apoptosis in Fetal Membranes: A Novel Mechanism to Explain Progesterone-Mediated Prevention of Preterm Birth

E. Norwitz, Jinsong Gao, E. Funai, 2010, Reproductive sciences.

Viral Single Stranded RNA Induces a Trophoblast Pro-Inflammatory and Antiviral Response in a TLR8-Dependent and -Independent Manner1

V. Abrahams, S. Girard, M. Garg, 2015, Biology of reproduction.

Running Title: Effect of viral ssRNA on trophoblast function and pregnancy

V. Abrahams, S. Girard, M. Garg, 2014 .

Isolation of Hofbauer Cells from Human Term Placentas with High Yield and Purity

G. Mor, E. Norwitz, S. Guller, 2011, American journal of reproductive immunology.

Placental Hofbauer cells and complications of pregnancy

G. Mor, S. Guller, V. Abrahams, 2011, Annals of the New York Academy of Sciences.

Antiphospholipid Antibodies Increase Endometrial Stromal Cell Decidualization, Senescence, and Inflammation via Toll‐like Receptor 4, Reactive Oxygen Species, and p38 MAPK Signaling

M. Tong, J. Salmon, S. Whirledge, 2022, Arthritis & rheumatology.

Reproductive Biology and Endocrinology Open Access Potential Role of Macrophages as Immunoregulators of Pregnancy

G. Mor, V. Abrahams, Edu, 2022 .

Low molecular weight heparin and aspirin exacerbate human endometrial endothelial cell responses to antiphospholipid antibodies

M. Tong, S. Guller, L. Chamley, 2018, American journal of reproductive immunology.

Effect of Hydroxychloroquine on Antiphospholipid Antibody‐Induced Changes in First Trimester Trophoblast Function

J. Brosens, C. Albert, M. Mulla, 2014, American journal of reproductive immunology.

Pravastatin does not prevent antiphospholipid antibody-mediated changes in human first trimester trophoblast function.

J. Brosens, M. Mulla, L. Chamley, 2012, Human reproduction.

Mechanisms of Endothelial Dysfunction in Antiphospholipid Syndrome: Association With Clinical Manifestations

M. Velasquez, M. Rojas, V. Abrahams, 2018, Front. Physiol..

Editorial: Translational Virology in Pregnancy

V. Abrahams, K. A. Adams Waldorf, 2022, Frontiers in Virology.

The serotonin reuptake inhibitor fluoxetine induces human fetal membrane sterile inflammation through p38 MAPK activation.

E. Norwitz, K. Yonkers, V. Abrahams, 2022, Journal of reproductive immunology.

Influence of stage of the reproductive cycle and estradiol on thymus cell antigen presentation

V. Abrahams, J. Fahey, C. Wira, 2003, The Journal of Steroid Biochemistry and Molecular Biology.

Induction of tumor necrosis factor alpha production by adhered human monocytes: a key role for Fcgamma receptor type IIIa in rheumatoid arthritis.

P. Lydyard, J. Edwards, V. Abrahams, 2000, Arthritis and rheumatism.

Cell type-specific expression and function of toll-like receptors 2 and 4 in human placenta: implications in fetal infection.

G. Krikun, G. Mor, S. Guller, 2007, Placenta.

Regulation of chemokine production in response to pro-inflammatory cytokines in first trimester decidual cells.

G. Krikun, M. Rahman, C. Lockwood, 2006, Journal of reproductive immunology.

Inflammation and pregnancy: the role of the immune system at the implantation site

G. Mor, S. Guller, V. Abrahams, 2011, Annals of the New York Academy of Sciences.

ApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in Mice

C. Mineo, P. Shaul, J. Salmon, 2016, Arthritis & rheumatology.

A Role for TLRs in the Regulation of Immune Cell Migration by First Trimester Trophoblast Cells1

G. Mor, R. Romero, S. Guller, 2005, The Journal of Immunology.

Toll-like receptors and their role in the trophoblast.

G. Mor, V. Abrahams, Gil Mor, 2005, Placenta.

Uric Acid Crystals Induce Placental Inflammation and Alter Trophoblast Function via an IL-1–Dependent Pathway: Implications for Fetal Growth Restriction

C. Sibley, C. Vaillancourt, V. Abrahams, 2017, The Journal of Immunology.

Toll-like receptor 4: a potential link between "danger signals," the innate immune system, and preeclampsia?

S. Saito, G. Mor, R. Romero, 2005, American journal of obstetrics and gynecology.

Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage.

J. Brosens, A. Coomarasamy, P. Bennett, 2022, Seminars in cell & developmental biology.

Identification of microRNAs That Regulate TLR2-Mediated Trophoblast Apoptosis and Inhibition of IL-6 mRNA

V. Abrahams, M. Garg, J. Potter, 2013, PloS one.

Glucose and Metformin Modulate Human First Trimester Trophoblast Function: a Model and Potential Therapy for Diabetes‐Associated Uteroplacental Insufficiency

C. Flannery, C. Pettker, M. Mulla, 2015, American journal of reproductive immunology.

Chlamydia trachomatis Infection Modulates Trophoblast Cytokine/Chemokine Production1

P. Kavathas, M. Mulla, V. Abrahams, 2009, The Journal of Immunology.

Chlamydia trachomatis Infection Modulates Trophoblast Cytokine / Chemokine Production 1

P. Kavathas, M. Mulla, V. Abrahams, 2009 .

Pattern Recognition at the Maternal-Fetal Interface

V. Abrahams, 2008, Immunological investigations.

246: Excess glucose levels limit first trimester trophoblast migration and induce an anti-angiogenic profile

C. Lockwood, V. Abrahams, S. Thung, 2011 .

A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis

R. Romero, S. Hassan, A. Tarca, 2017, Reproductive Sciences.

A Role for the Inflammasome in Spontaneous Preterm Labor With Acute Histologic Chorioamnionitis

R. Romero, S. Hassan, A. Tarca, 2017, Reproductive Sciences.

Placental macrophage responses to viral and bacterial ligands and the influence of fetal sex

M. Kaforou, S. Guller, V. Abrahams, 2022, iScience.

Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

J. Cross, Y. Sadovsky, G. Bidwell, 2016, American journal of obstetrics and gynecology.

Expression and secretion of antiviral factors by trophoblast cells following stimulation by the TLR-3 agonist, Poly(I : C).

G. Mor, I. Visintin, V. Abrahams, 2006, Human reproduction.

Viral ssRNA Induces First Trimester Trophoblast Apoptosis through an Inflammatory Mechanism

G. Mor, R. Romero, M. Mulla, 2010, American journal of reproductive immunology.

Dendritic cells in the circulation of women with preeclampsia demonstrate a pro-inflammatory bias secondary to dysregulation of TLR receptors.

M. Altfeld, A. Panda, A. Shaw, 2012, Journal of reproductive immunology.

Molecular Regulation of Parturition: The Role of the Decidual Clock.

E. Norwitz, Joong-Shin Park, M. Phillippe, 2015, Cold Spring Harbor perspectives in medicine.

Antiphospholipid antibody‐induced trophoblast responses are differentially modulated by viral dsRNA and viral ssRNA

L. Chamley, V. Abrahams, Deidre M Jones, 2021, American journal of reproductive immunology.

Modulation of trophoblast function by concurrent hyperglycemia and antiphospholipid antibodies is in part TLR4‐dependent

M. Mulla, L. Chamley, V. Abrahams, 2018, American journal of reproductive immunology.

Antiphospholipid antibodies limit trophoblast migration by reducing IL‐6 production and STAT3 activity

J. Brosens, M. Mulla, L. Chamley, 2011 .

Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity.

R. Nussinov, C. Kriegel, W. Kwok, 2019, Cell host & microbe.

Toll-Like Receptors in the Cycling Female Reproductive Tract and During Pregnancy

V. Abrahams, 2005 .

A Role for the Inflammasome in Spontaneous Labor at Term

R. Romero, S. Hassan, A. Tarca, 2018, American journal of reproductive immunology.

Relevance of placental type I interferon beta regulation for pregnancy success

G. Mor, R. Romero, V. Abrahams, 2018, Cellular & Molecular Immunology.

Type I Interferon Regulates the Placental Inflammatory Response to Bacteria and is Targeted by Virus: Mechanism of Polymicrobial Infection‐Induced Preterm Birth

R. Romero, A. El-Guindy, V. Abrahams, 2016, American journal of reproductive immunology.

Syncytin 1 in the human placenta.

V. Abrahams, J. Aplin, C. Tower, 2012, Placenta.

Viral infection dampens human fetal membrane type I interferon responses triggered by bacterial LPS.

M. Tong, V. Abrahams, J. Kwon, 2020, Journal of reproductive immunology.

Low Molecular Weight Heparin Modulates Maternal Immune Response in Pregnant Women and Mice with Thrombophilia

A. Zenclussen, A. Schumacher, M. Mulla, 2015, American journal of reproductive immunology.

Inflammasome assembly in the chorioamniotic membranes during spontaneous labor at term

R. Romero, S. Hassan, N. Gomez‐Lopez, 2017, American journal of reproductive immunology.

Macrophage-trophoblast interactions.

G. Mor, V. Abrahams, S. Straszewski-Chavez, 2006, Methods in molecular medicine.

Uric acid crystals induces placental inflammation and alters trophoblast function via an IL-1-dependent pathway : implication for FGR

C. Sibley, C. Vaillancourt, V. Abrahams, 2016 .

Toll‐Like Receptor 4 Expression in Decidual Cells and Interstitial Trophoblasts Across Human Pregnancy

G. Krikun, U. Kayisli, C. Lockwood, 2012, American journal of reproductive immunology.

Lipopolysaccharide Appears to Activate Human Endometrial Endothelial Cells Through TLR‐4‐Dependent and TLR‐4‐Independent Mechanisms

G. Krikun, C. Lockwood, S. Guller, 2012, American journal of reproductive immunology.

Antagonizing Toll-like Receptors to Prevent Preterm Labor

V. Abrahams, 2008, Reproductive Sciences.

Excess glucose induce trophoblast inflammation and limit cell migration through HMGB1 activation of Toll‐Like receptor 4

S. Guller, M. Mulla, V. Abrahams, 2018, American journal of reproductive immunology.

Expression of Toll-like receptors in the human decidua.

G. Krikun, C. Lockwood, S. Guller, 2007, Histology and histopathology.

Novel mechanisms of placental inflammation in obstetric antiphospholipid syndrome

V. Abrahams, 2017 .

Cell-free fetal DNA impairs trophoblast migration in a TLR9-dependent manner and can be reversed by hydroxychloroquine.

V. Abrahams, D. Leon-Martinez, T. Lynn, 2023, Journal of reproductive immunology.

Decidualization dampens toll-like receptor mediated inflammatory responses in human endometrial stromal cells by upregulating IκBα.

M. Tong, S. Whirledge, V. Abrahams, 2023, Journal of reproductive immunology.

Endometrial responses to bacterial and viral infection: a scoping review.

M. Tong, V. Abrahams, A. Grimshaw, 2023, Human reproduction update.

Reproductive immunology: the clinical view

V. Abrahams, 2011, Expert review of clinical immunology.

Thrombin Augments LPS‐Induced Human Endometrial Endothelial Cell Inflammation via PAR1 Activation

G. Krikun, C. Lockwood, V. Abrahams, 2016, American journal of reproductive immunology.

Relevance of placental type I interferon beta regulation for pregnancy success

L. Wen, G. Mor, R. Romero, 2018, Cellular & Molecular Immunology.

Do self‐perpetuating B lymphocytes drive human autoimmune disease?

J. Edwards, V. Abrahams, G. Cambridge, 1999, Immunology.

Toll‐like Receptor‐Mediated Responses by Placental Hofbauer Cells (HBCs): A Potential Pro‐Inflammatory Role for Fetal M2 Macrophages

G. Krikun, G. Mor, E. Norwitz, 2015, American journal of reproductive immunology.

Focal Increases of Fetal Macrophages in Placentas from Pregnancies with Histological Chorioamnionitis: Potential Role of Fibroblast Monocyte Chemotactic Protein‐1

G. Krikun, G. Mor, C. Lockwood, 2011, American journal of reproductive immunology.

ApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in Mice

C. Mineo, P. Shaul, J. Salmon, 2016, Arthritis & rheumatology.

Macrophages and Pregnancy

G. Mor, K. Koga, V. Abrahams, 2008 .

Type I Interferon Regulates the Placental Inflammatory Response to Bacteria and is Targeted by Virus: Mechanism of Polymicrobial Infection‐Induced Preterm Birth

R. Romero, A. El-Guindy, V. Abrahams, 2016, American journal of reproductive immunology.

Human Endometrial Endothelial Cells Generate Distinct Inflammatory and Antiviral Responses to the TLR3 agonist, Poly(I:C) and the TLR8 agonist, viral ssRNA

G. Krikun, V. Abrahams, J. Potter, 2013, American journal of reproductive immunology.

Viral ssRNA Induces First Trimester Trophoblast Apoptosis through an Inflammatory Mechanism

G. Mor, R. Romero, M. Mulla, 2010, American journal of reproductive immunology.

Antiphospholipid antibody-induced miR-146a-3p drives trophoblast interleukin-8 secretion through activation of Toll-like receptor 8.

J. Brosens, J. Salmon, M. Mulla, 2016, Molecular human reproduction.

Effect of Hydroxychloroquine on Antiphospholipid Antibody‐Induced Changes in First Trimester Trophoblast Function

J. Brosens, M. Mulla, L. Chamley, 2014, American journal of reproductive immunology.

Pre‐eclampsia is associated with dendritic cell recruitment into the uterine decidua

Chie-Pein Chen, V. Abrahams, F. Schatz, 2008, The Journal of pathology.

EDITORIAL: Thirty Years of Reproductive Immunology: An Introduction

V. Abrahams, 2010, American journal of reproductive immunology.

Antiphospholipid-exposed trophoblast-derived extracellular vesicles express elevated levels of TLR7/8-activating microRNAs and induce endometrial endothelial activation, in part, through TLR7.

L. Chamley, V. Abrahams, Tiffany N. Hidalgo, 2024, Journal of reproductive immunology.

Placental Hofbauer cells and complications of pregnancy

G. Mor, S. Guller, V. Abrahams, 2011, Annals of the New York Academy of Sciences.