A. Ozinsky

发表

Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages.

A. Aderem, K. Smith, D. Underhill, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

A. Aderem, D. Underhill, Christopher B Wilson, 1999, Nature.

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

S. Akira, J. Eng, D. Goodlett, 2001, Nature.

Bright Field Microscopy as an Alternative to Whole Cell Fluorescence in Automated Analysis of Macrophage Images

Pekka Ruusuvuori, Ilya Shmulevich, Olli Yli-Harja, 2009, PloS one.

The low density lipoprotein receptor

G. Coetzee, A. Ozinsky, D. Westhuyzen, 1996 .

Phenol-Soluble Modulin TLR1 or TLR6 in Response to Between Toll-Like Receptor (TLR) 2 and Cutting Edge: Functional Interactions

A. Aderem, D. Underhill, Christopher B Wilson, 2000 .

Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist

K. Walters, A. Ozinsky, S. Skerrett, 2015, BMC Genomics.

Toll-like receptors: key mediators of microbe detection.

Adrian Ozinsky, D. Underhill, A. Ozinsky, 2002, Current opinion in immunology.

Leishmania major activates IL-1α expression in macrophages through a MyD88-dependent pathway

S. Akira, A. Aderem, F. Buckner, 2002 .

Phagocytosis of microbes: complexity in action.

Adrian Ozinsky, D. Underhill, A. Ozinsky, 2002, Annual review of immunology.

Cutting Edge: Functional Interactions Between Toll-Like Receptor (TLR) 2 and TLR1 or TLR6 in Response to Phenol-Soluble Modulin1

A. Aderem, D. Underhill, Christopher B Wilson, 2001, The Journal of Immunology.

Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency

A. Al-ghonaium, Sami Al-Hajjar, S. Al-Jumaah, 2003, Science.

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.

A. Aderem, K. Smith, D. Underhill, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Hyper-IgE syndrome is not associated with defects in several candidate toll-like receptor pathway genes.

Stephanie D Rodrigues, A. Aderem, H. Ochs, 2005, Human immunology.

A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

Richard J. Laws, L. Zhao, A. Aderem, 2003, The Journal of experimental medicine.

Differential Role of MyD88 in Macrophage-Mediated Responses to Opportunistic Fungal Pathogens

S. Akira, A. Aderem, T. Hawn, 2003, Infection and Immunity.

PHAGOCYTOSIS OF MICROBES

D. Underhill, A. Ozinsky, 2002 .

Toll-like receptor-5 and the innate immune response to bacterial flagellin.

K. Smith, A. Ozinsky, Kelly D. Smith, 2002, Current topics in microbiology and immunology.

Edinburgh Research Explorer Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

Alan Aderem, A. Aderem, D. Hume, 2001 .

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism

A. Aderem, D. Underhill, P. Godowski, 2001, Nature Immunology.

Human TLR-7-, -8-, and -9-Mediated Induction of IFN-α/β and -λ Is IRAK-4 Dependent and Redundant for Protective Immunity to Viruses

A. Al-ghonaium, Sami Al-Hajjar, J. Casanova, 2005, Immunity.

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response

K. Walters, J. F. Atkins, J. Taubenberger, 2012, Science.

Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice.

K. Walters, J. Taubenberger, J. D. Easterbrook, 2014, Free radical biology & medicine.

Transcriptional noise and cellular heterogeneity in mammalian macrophages

H Bolouri, V. Thorsson, H. Bolouri, 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

Resolving Cell Population Heterogeneity: Real-Time PCR for Simultaneous Multiplexed Gene Detection in Multiple Single-Cell Samples

Adrian Ozinsky, A. Diercks, A. Ozinsky, 2009, PloS one.

Isolation and characterization of monoclonal antibodies directed against novel components of macrophage phagosomes.

E. Gold, A. Aderem, V. Bedian, 1999, Journal of cell science.

Binding specificity of Toll‐like receptor cytoplasmic domains

S. Fields, J. Hesselberth, A. Ozinsky, 2006, European journal of immunology.

Co-operative induction of pro-inflammatory signaling by Toll-like receptors

D. Hume, D. Underhill, Kelly D. Smith, 2000, Journal of endotoxin research.

Integrative analysis of N-linked human glycoproteomic data sets reveals PTPRF ectodomain as a novel plasma biomarker candidate for prostate cancer.

Daniel B. Martin, P. Nelson, T. Holzman, 2012, Journal of proteome research.

A microfluidic device for multiplexed protein detection in nano-liter volumes.

Alan Aderem, Carl L Hansen, James M Spotts, 2009, Analytical biochemistry.

Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist

K. Walters, A. Ozinsky, S. Skerrett, 2015, BMC Genomics.

Francisella tularensis subsp. tularensis Induces a Unique Pulmonary Inflammatory Response: Role of Bacterial Gene Expression in Temporal Regulation of Host Defense Responses

K. Walters, Ji-Hoon Cho, Hong Li, 2013, PloS one.

Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis.

A. Aderem, M. Malbouyres, T. Soldati, 2003, Molecular biology of the cell.

Lethal Synergism of 2009 Pandemic H1N1 Influenza Virus and Streptococcus pneumoniae Coinfection Is Associated with Loss of Murine Lung Repair Responses

K. Walters, J. Taubenberger, A. Davis, 2011, mBio.

Specificity in Toll-like receptor function

A. Ozinsky, 2001 .

Edinburgh Research Explorer Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

A. Aderem, D. Hume, M. Sweet, 2001 .

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

A. Aderem, D. Underhill, Christopher B Wilson, 1999, Nature.

Edinburgh Research Explorer Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

A. Aderem, M. Sweet, A. Ozinsky, 2001 .

Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

A. Aderem, M. Sweet, A. Ozinsky, 2001, BMC Immunology.

A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

Richard J. Laws, L. Zhao, A. Aderem, 2003, The Journal of experimental medicine.

Image-based feedback control for real-time sorting of microspheres in a microfluidic device.

J. M. Spotts, J. Kralj, J. Selinummi, 2010, Lab on a chip.