P. Mcguirk

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Myocardial Ischemia / Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti – Toll-Like Receptor-2 Antibody

P. Doevendans, G. Pasterkamp, M. Smeets, 2009 .

Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells.

K. Mills, A. Moore, D. O'hagan, 1995, Vaccine.

Toll-Like Receptor 4-Mediated Innate IL-10 Activates Antigen-Specific Regulatory T Cells and Confers Resistance to Bordetella pertussis by Inhibiting Inflammatory Pathology 1

K. Mills, E. Lavelle, A. Jarnicki, 2003, The Journal of Immunology.

Identification of TLR2 Signalling Mechanisms Which Contribute to Barrett’s and Oesophageal Adenocarcinoma Disease Progression

J. O’Sullivan, C. Nulty, B. Keogh, 2021, Cancers.

Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer

T. Ushijima, L. Yu, B. Jenkins, 2017, Oncogene.

A Regulatory Role for Interleukin 4 in Differential Inflammatory Responses in the Lung following Infection of Mice Primed with Th1- or Th2-Inducing Pertussis Vaccines

K. Mills, P. Mcguirk, 2000, Infection and Immunity.

Regulatory cells and the control of respiratory infection

K. Mills, P. Mcguirk, S. Higgins, 2005, Current allergy and asthma reports.

The Role of Regulatory T Cells in Respiratory Infections and Allergy and Asthma

K. Mills, P. Mcguirk, S. Higgins, 2010, Current allergy and asthma reports.

Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule

D. Hommes, S. V. van Deventer, H. Braat, 2006, Gut.

Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

D. Veale, U. Fearon, J. Dellacasagrande, 2011, Arthritis Research & Therapy.

Treatment With OPN-305, a Humanized Anti–Toll-Like Receptor-2 Antibody, Reduces Myocardial Ischemia/Reperfusion Injury in Pigs

G. Pasterkamp, J. Houtgraaf, M. Smeets, 2012, Circulation. Cardiovascular interventions.

Antigen-specific regulatory T cells--their induction and role in infection.

K. Mills, P. Mcguirk, 2004, Seminars in immunology.

Direct anti‐inflammatory effect of a bacterial virulence factor: IL‐10‐dependent suppression of IL‐12 production by filamentous hemagglutinin from Bordetella pertussis

K. Mills, P. Mcguirk, 2000, European journal of immunology.

Pathogen-speciﬁc T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells: A Novel Strategy for Evasion of Protective T Helper Type 1 Responses by Bordetella pertussis

K. Mills, P. Mcguirk, Chantelle McCann, 2002 .

Pathology by Inhibiting Inflammatory pertussis Bordetella and Confers Resistance to Cells Activates Antigen-Specific Regulatory T Toll-Like Receptor 4-Mediated Innate IL-10

K. Mills, A. Jarnicki, P. Mcguirk, 2003 .

Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen‐specific Th1 and enhancement of Th2, but not Tr1 cells

K. Mills, S. Todryk, P. Mcguirk, 2004, European journal of immunology.

Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer’s disease

M. Lynch, C. McDonald, B. Keogh, 2016, Brain, Behavior, and Immunity.

Filamentous hemagglutinin and pertussis toxin from Bordetella pertussis modulate immune responses to unrelated antigens.

K. Mills, P. Johnson, P. Mcguirk, 2000, The Journal of infectious diseases.

Pathogen-specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells

K. Mills, P. Mcguirk, Chantelle McCann, 2002, The Journal of experimental medicine.

Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases.

K. Mills, P. Mcguirk, 2002, Trends in immunology.

Mechanisms of Disease: the hygiene hypothesis revisited

F. Guarner, J. Versalovic, G. Rook, 2006, Nature Clinical Practice Gastroenterology &Hepatology.

TLR2 and TLR4 in Ischemia Reperfusion Injury

B. Keogh, A. Parker, F. Arslan, 2010, Mediators of inflammation.

Vaccines with Th 1-or Th 2-Inducing Pertussis Lung following Infection of Mice Primed Differential Inflammatory Responses in the A Regulatory Role for Interleukin 4 in

K. Mills, P. Mcguirk, 2000 .

Compartmentalization of T cell responses following respiratory infection with Bordetella pertussis: hyporesponsiveness of lung T cells is associated with modulated expression of the co-stimulatory molecule CD28.

K. Mills, P. Mcguirk, B. Mahon, 1998, European journal of immunology.

The immunology of bordetella pertussis infection.

K. Mills, P. Mcguirk, M. Ryan, 1999, Biologicals (Print).

A Clinical Study of Tomaralimab (OPN-305), a Toll-like Receptor 2 (TLR-2) Antibody, in Heavily Pre-Treated Transfusion Dependent Patients with Lower Risk Myelodysplastic Syndromes (MDS) That Have Received and Failed on Prior Hypomethylating Agent (HMA) Therapy

M. Konopleva, H. Kantarjian, G. Garcia-Manero, 2018, Blood.

Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody

P. Doevendans, G. Pasterkamp, M. Smeets, 2010, Circulation.

Molecules of infectious agents as immunomodulatory drugs.

K. Mills, E. Lavelle, P. Mcguirk, 2004, Current topics in medicinal chemistry.

Receptor-2 Antibody Receptor-2 and Reduced by Systemic Administration of a Novel Anti Toll-Like Myocardial Ischemia / Reperfusion Injury

P. Doevendans, M. Smeets, D. D. de Kleijn, 2009 .

Direct anti‐inflammatory effect of a bacterial virulence factor: IL‐10‐dependent suppression of IL‐12 production by filamentous hemagglutinin from Bordetella pertussis

K. Mills, P. Mcguirk, 2000, European journal of immunology.