Li Liu

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TLR2 Ligand Induces Protection against Cerebral Ischemia/Reperfusion Injury via Activation of Phosphoinositide 3-Kinase/Akt Signaling

J. Kalbfleisch, David L. Williams, Yuling Chen, 2011, The Journal of Immunology.

Attenuation of Cardiac Dysfunction in Polymicrobial Sepsis by MicroRNA-146a Is Mediated via Targeting of IRAK1 and TRAF6 Expression

J. Kalbfleisch, David L. Williams, R. Kao, 2015, The Journal of Immunology.

TRAF 6 Expression Mediated via Targeting of IRAK 1 and Polymicrobial Sepsis by MicroRNA-146 a Is Attenuation of Cardiac Dysfunction in

J. Kalbfleisch, David L. Williams, R. Kao, 2015 .

Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsis*

David L. Williams, Krishna Singh, R. Kao, 2010, Critical care medicine.

HSPA12B inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells

Yuehua Li, Chuanful Li, Li Liu, 2014, Journal of cellular and molecular medicine.

Alpha‐lipoic acid inhibits lung cancer growth via mTOR‐mediated autophagy inhibition

Qiuyue Kong, Li Liu, Xiaojin Zhang, 2020, FEBS open bio.

HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation

Qiuyue Kong, Yuehua Li, Chuanful Li, 2016, Oxidative medicine and cellular longevity.

Glucan phosphate attenuates myocardial HMGB1 translocation in severe sepsis through inhibiting NF-κB activation.

J. Kalbfleisch, David L. Williams, R. Kao, 2011, American journal of physiology. Heart and circulatory physiology.

Attenuation of cardiac dysfunction and remodeling of myocardial infarction by microRNA-130a are mediated by suppression of PTEN and activation of PI3K dependent signaling.

J. Kalbfleisch, R. Kao, T. Ha, 2015, Journal of molecular and cellular cardiology.

Toll-like receptor 3 plays a role in myocardial infarction and ischemia/reperfusion injury.

J. Kalbfleisch, R. Kao, T. Ha, 2014, Biochimica et biophysica acta.

Increased expression of microRNA-146a decreases myocardial ischaemia/reperfusion injury.

J. Kalbfleisch, T. Ha, Xiang Gao, 2013, Cardiovascular research.

HSPA12B promotes functional recovery after ischaemic stroke through an eNOS‐dependent mechanism

Qiuyue Kong, Jiali Liu, Yuehua Li, 2018, Journal of cellular and molecular medicine.

Heat shock protein A12A encodes a novel prosurvival pathway during ischaemic stroke.

Qiuyue Kong, Yuehua Li, Chuanful Li, 2018, Biochimica et biophysica acta. Molecular basis of disease.

Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.

Qiuyue Kong, Li Liu, Xiaojin Zhang, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Downregulation of HSPA12A underlies myotoxicity of local anesthetic agent bupivacaine through inhibiting PGC1α-mediated mitochondrial integrity.

Shijiang Liu, Li Liu, Xiaojin Zhang, 2021, Toxicology and applied pharmacology.

CpG-ODN, the TLR9 agonist, attenuates myocardial ischemia/reperfusion injury: involving activation of PI3K/Akt signaling.

J. Kalbfleisch, R. Kao, T. Ha, 2013, Biochimica et biophysica acta.

This information is current as Signaling Activation of Phosphoinositide 3-Kinase / Akt Cerebral Ischemia / Reperfusion Injury via TLR 2 Ligand Induces Protection against

J. Kalbfleisch, David L. Williams, R. Kao, 2011 .

TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism.

J. Kalbfleisch, David L. Williams, R. Kao, 2010, American Journal of Physiology. Heart and Circulatory Physiology.

TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism.

David L. Williams, R. Kao, J. McMullen, 2010, Cardiovascular research.

TLR 2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism

J. Kalbfleisch, David L. Williams, R. Kao, 2010 .

Over‐expression of heat shock protein 27 attenuates doxorubicin‐induced cardiac dysfunction in mice

Xiang Gao, Chuanful Li, Li Liu, 2007, European journal of heart failure.

The TIR/BB‐loop mimetic AS‐1 prevents non‐alcoholic steatohepatitis and hepatic insulin resistance by inhibiting NLRP3‐ASC inflammasome activation

Yun Gao, Yuehua Li, Li Liu, 2017, British journal of pharmacology.

Peli1 induction impairs cardiac microvascular endothelium through Hsp90 dissociation from IRE1α.

T. Ha, Yuehua Li, Chuanful Li, 2019, Biochimica et biophysica acta. Molecular basis of disease.

HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization

Qiuyue Kong, Lei Fang, Yuehua Li, 2018, Diabetes.

α-Lipoic acid protected cardiomyoblasts from the injury induced by sodium nitroprusside through ROS-mediated Akt/Gsk-3β activation.

K. Cao, Yuehua Li, Chuanful Li, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

CARDIAC-SPECIFIC EXPRESSION OF HEAT SHOCK PROTEIN 27 ATTENUATED ENDOTOXIN-INDUCED CARDIAC DYSFUNCTION AND MORTALITY IN MICE THROUGH A PI3K/AKT-DEPENDENT MECHANISM

Xiang Gao, Chuanful Li, Li Liu, 2009, Shock.

Involvement of Reductive Stress in the Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Heat Shock Protein 27

I. Benjamin, Xiang Gao, Chuanful Li, 2010, Hypertension.

Pellino1-mediated TGF-β1 synthesis contributes to mechanical stress induced cardiac fibroblast activation.

Yun Gao, T. Ha, Yuehua Li, 2015, Journal of molecular and cellular cardiology.

Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages.

David L. Williams, R. Kao, T. Ha, 2012, Biochimica et biophysica acta.

HSPA12B attenuates acute lung injury during endotoxemia in mice.

Yuehua Li, Chuanful Li, Li Liu, 2015, International immunopharmacology.

MEK/ERKs signaling is essential for lithium-induced neurite outgrowth in N2a cells

G. Ding, Chuanful Li, Li Liu, 2011, International Journal of Developmental Neuroscience.

Elevated ZIPK is required for TNF-α-induced cell adhesion molecule expression and leucocyte adhesion in endothelial cells.

Qianqian Zhang, Li Liu, Weiwei Zeng, 2021, Acta biochimica et biophysica Sinica.

HSPA12A is required for adipocyte differentiation and diet-induced obesity through a positive feedback regulation with PPARγ

Qiuyue Kong, Hao Cheng, Yuehua Li, 2019, Cell Death & Differentiation.

Autophagy activated by tuberin/mTOR/p70S6K suppression is a protective mechanism against local anaesthetics neurotoxicity

Qiuyue Kong, Li Liu, Zhengnian Ding, 2016, Journal of cellular and molecular medicine.

Overexpressing dominant negative MyD88 induces cardiac dysfunction in transgenic mice

Xiang Gao, Chuanful Li, Li Liu, 2010 .

Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth

Qiuyue Kong, Lei Fang, Li Liu, 2020, The FEBS journal.

Impaired Autophagosome Clearance Contributes to Local Anesthetic Bupivacaine-induced Myotoxicity in Mouse Myoblasts

J. Dai, Chuanful Li, Li Liu, 2015, Anesthesiology.

Lactate induces vascular permeability via disruption of VE-cadherin in endothelial cells during sepsis

David L. Williams, T. Ha, Chuanful Li, 2022, Science advances.

Essential role of ERK activation in neurite outgrowth induced by α-lipoic acid.

G. Ding, Chuanful Li, Li Liu, 2011, Biochimica et biophysica acta.

Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis

David L. Williams, T. Ha, Chuanful Li, 2021, Cell death and differentiation.

MicroRNA-125b Prevents Cardiac Dysfunction in Polymicrobial Sepsis by Targeting TRAF6-Mediated Nuclear Factor κB Activation and p53-Mediated Apoptotic Signaling.

J. Kalbfleisch, David L. Williams, R. Kao, 2016, The Journal of infectious diseases.

MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6.

J. Kalbfleisch, David L. Williams, T. Ha, 2014, Cardiovascular research.

HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression

Qiuyue Kong, Jiali Liu, Yuehua Li, 2020, Cell Death & Differentiation.

Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis

David L. Williams, T. Ha, Chuanful Li, 2021, Cell Death & Differentiation.

α-Lipoic acid increases tolerance of cardiomyoblasts to glucose/glucose oxidase-induced injury via ROS-dependent ERK1/2 activation.

Chuanful Li, Li Liu, Xiaojin Zhang, 2012, Biochimica et biophysica acta.

TLR3 Mediates Repair and Regeneration of Damaged Neonatal Heart through Glycolysis Dependent YAP1 Regulated miR-152 Expression

J. Kalbfleisch, R. Kao, T. Ha, 2018, Cell Death & Differentiation.

Poly (I:C) therapy decreases cerebral ischaemia/reperfusion injury viaTLR3-mediated prevention of Fas/FADD interaction

J. Kalbfleisch, David L. Williams, R. Kao, 2014, Journal of cellular and molecular medicine.

Role of Toll-Like Receptors in Myocardial Ischemia/Reperfusion Injury

David L. Williams, T. Ha, J. Kelley, 2013 .

Toll-like receptors: new players in myocardial ischemia/reperfusion injury.

David L. Williams, R. Kao, T. Ha, 2011, Antioxidants & redox signaling.

Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis

J. Kalbfleisch, Jingjing Xu, R. Kao, 2017, The Journal of infectious diseases.

SR-A deficiency reduces myocardial ischemia/reperfusion injury; involvement of increased microRNA-125b expression in macrophages.

J. Kalbfleisch, T. Ha, Xiang Gao, 2013, Biochimica et biophysica acta.

Alpha-lipoic acid prevents bupivacaine-induced neuron injury in vitro through a PI3K/Akt-dependent mechanism.

Chuanful Li, Li Liu, Xiaojin Zhang, 2010, Neurotoxicology.

The TLR 9 Ligand , CpG-ODN , Induces Protection against Cerebral Ischemia / Reperfusion Injury via Activation of PI 3 K / Akt Signaling

T. Ha, Chuanful Li, Chen Lu, 2014 .

The TLR9 Ligand, CpG‐ODN, Induces Protection against Cerebral Ischemia/Reperfusion Injury via Activation of PI3K/Akt Signaling

J. Kalbfleisch, T. Ha, Chuanful Li, 2014, Journal of the American Heart Association.

Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126

J. Kalbfleisch, T. Ha, Chuanful Li, 2020, Frontiers in Immunology.

Scavenger Receptor Class-A Has a Central Role in Cerebral Ischemia–Reperfusion Injury

J. Kalbfleisch, David L. Williams, R. Kao, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

HSPA12A unstabilizes CD147 to inhibit lactate export and migration in human renal cell carcinoma

Qiuyue Kong, Yuehua Li, Chuanful Li, 2020, Theranostics.

Overexpression of HSPA12B protects against cerebral ischemia/reperfusion injury via a PI3K/Akt-dependent mechanism.

Chuanful Li, Chen Lu, Li Liu, 2013, Biochimica et biophysica acta.

Heat shock protein A12A activates migration of hepatocellular carcinoma cells in a monocarboxylate transporter 4–dependent manner

Lei Fang, Li Liu, Xiaojin Zhang, 2022, Cell Stress and Chaperones.

α-Lipoic acid attenuates LPS-induced cardiac dysfunction through a PI3K/Akt-dependent mechanism.

K. Cao, Chuanful Li, Li Liu, 2013, International immunopharmacology.

Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction

David L. Williams, T. Ha, Chuanful Li, 2023, Science advances.

Endothelial cell HSPA12B and yes-associated protein cooperatively regulate angiogenesis following myocardial infarction

David L. Williams, T. Ha, Chuanful Li, 2020, JCI insight.

The Toll-like receptor 9 ligand, CpG oligodeoxynucleotide, attenuates cardiac dysfunction in polymicrobial sepsis, involving activation of both phosphoinositide 3 kinase/Akt and extracellular-signal-related kinase signaling.

J. Kalbfleisch, T. Ha, Chuanful Li, 2013, The Journal of infectious diseases.

Silencing of Pellino1 improves post-infarct cardiac dysfunction and attenuates left ventricular remodelling in mice.

T. Ha, Yuehua Li, Chuanful Li, 2014, Cardiovascular research.

Heat shock protein 27 regulates oxidative stress-induced apoptosis in cardiomyocytes: mechanisms via reactive oxygen species generation and Akt activation.

Guo-xian Ding, Li Liu, Xiaojin Zhang, 2007, Chinese medical journal.

MicroRNA-214 protects against hypoxia/reoxygenation induced cell damage and myocardial ischemia/reperfusion injury via suppression of PTEN and Bim1 expression

J. Kalbfleisch, David L. Williams, R. Kao, 2016, Oncotarget.

HSPA12B attenuates cardiac dysfunction and remodelling after myocardial infarction through an eNOS-dependent mechanism.

Y. Liu, Chuanful Li, Li Liu, 2013, Cardiovascular research.

Cardiomyocyte-specific deficiency of HSPB1 worsens cardiac dysfunction by activating NF&kgr;B-mediated leucocyte recruitment after myocardial infarction

Qiuyue Kong, Jiali Liu, Yuehua Li, 2018, Cardiovascular research.

Triad3A attenuates pathological cardiac hypertrophy involving the augmentation of ubiquitination-mediated degradation of TLR4 and TLR9

T. Ha, Yuehua Li, Chuanful Li, 2020, Basic Research in Cardiology.

HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism

Qiuyue Kong, Yuehua Li, Chuanful Li, 2016, Scientific Reports.

HSPA12A Stimulates p38/ERK-AP-1 Signaling to Promote Angiogenesis and Is Required for Functional Recovery Postmyocardial Infarction

Yuehua Li, Chuanful Li, Li Liu, 2022, Oxidative medicine and cellular longevity.

HSPA12A improves endothelial integrity to attenuate lung injury during endotoxemia through activating ERKs and Akt-dependent signaling.

Jiali Liu, Li Liu, Xiaojin Zhang, 2021, International immunopharmacology.

Attenuation of cardiac dysfunction by HSPA12B in endotoxin-induced sepsis in mice through a PI3K-dependent mechanism.

Xiang Gao, Chuanful Li, Li Liu, 2011, Cardiovascular research.

TLR3 Mediates Repair and Regeneration of Damaged Neonatal Heart through Glycolysis Dependent YAP1 Regulated miR-152 Expression

J. Kalbfleisch, David L. Williams, R. Kao, 2018, Cell Death & Differentiation.

Hepatocyte HSPA12A inhibits macrophage chemotaxis and activation to attenuate liver ischemia/reperfusion injury via suppressing glycolysis-mediated HMGB1 lactylation and secretion of hepatocytes

Qiuyue Kong, Yuehua Li, Chuanful Li, 2023, Theranostics.

HSPA12B: a novel facilitator of lung tumor growth

Yuehua Li, Chuanful Li, Li Liu, 2015, Oncotarget.

Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis

David L. Williams, T. Ha, Chuanful Li, 2020, Frontiers in Immunology.

HSPA12A controls cerebral lactate homeostasis to maintain hippocampal neurogenesis and mood stabilization

Yuehua Li, Chuanful Li, Li Liu, 2023, Translational psychiatry.

The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb–mTORC1 signalling and leads to chronic heart failure

Li Liu, Yang Yu, Jun Xie, 2015, The Journal of pathology.