D. Sacks

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In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

M. Fay, J. Egen, R. Germain, 2008, Science.

Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage

M. Berriman, W. Warren, C. Durrant, 2017, mBio.

Interleukin-10 and the pathogenesis of human visceral leishmaniasis.

D. Sacks, S. Nylén, 2007, Trends in immunology.

Identification and partial characterization of a lipophosphoglycan from a pathogenic strain of Entamoeba histolytica.

A. Bhattacharya, D. Sacks, R. Prasad, 1992, Molecular and biochemical parasitology.

Why does immunity to parasites take so long to develop?

M. Yazdanbakhsh, D. Sacks, 2010, Nature Reviews Immunology.

Immunization of mice against African trypanosomiasis using anti- idiotypic antibodies

A. Sher, K. Esser, D. Sacks, 1982, The Journal of experimental medicine.

Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the Mouse Ear Dermis

Y. Belkaid, S. Kamhawi, G. Modi, 1998, The Journal of experimental medicine.

Asymptomatic Leishmania infection: a new challenge for Leishmania control.

O. Singh, S. Sundar, M. Boelaert, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Protection against cutaneous leishmaniasis resulting from bites of uninfected sand flies.

Y. Belkaid, S. Kamhawi, G. Modi, 2000, Science.

Delayed-type hypersensitivity to Phlebotomus papatasi sand fly bite: An adaptive response induced by the fly?

Y. Belkaid, J. Ribeiro, S. Kamhawi, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The midgut microbiota plays an essential role in sand fly vector competence for Leishmania major

M. Lewis, P. Lawyer, Margery G. Smelkinson, 2017, Cellular microbiology.

The Potential Use of Forensic DNA Methods Applied to Sand Fly Blood Meal Analysis to Identify the Infection Reservoirs of Anthroponotic Visceral Leishmaniasis

D. Sacks, D. Podini, E. Inbar, 2016, PLoS neglected tropical diseases.

Nonhealing Infection despite Th1 Polarization Produced by a Strain of Leishmania major in C57BL/6 Mice

D. Sacks, Charles F. Anderson, S. Mendez, 2005, The Journal of Immunology.

Tumor necrosis factor alpha neutralization has no direct effect on parasite burden, but causes impaired IFN-γ production by spleen cells from human visceral leishmaniasis patients.

R. Kumar, S. Sundar, C. Engwerda, 2016, Cytokine.

The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti–IL-10 Receptor Antibody for Sterile Cure

Y. Belkaid, T. Wynn, S. Kamhawi, 2001, The Journal of experimental medicine.

A Role for Insect Galectins in Parasite Survival

C. Barillas-Mury, S. Kamhawi, J. Valenzuela, 2004, Cell.

Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis

J. Brenchley, M. Lewis, A. Paun, 2020, PLoS Pathogens.

The Mating Competence of Geographically Diverse Leishmania major Strains in Their Natural and Unnatural Sand Fly Vectors

M. Fay, D. Dobson, S. Beverley, 2013, PLoS genetics.

Molecular Aspects of Parasite – Vector Interactions In Leishmaniasis

D. Sacks, 2010 .

The role of dermis resident macrophages and their interaction with neutrophils in the early establishment of Leishmania major infection transmitted by sand fly bite

O. Kamenyeva, D. Sacks, K. Ghosh, 2020, bioRxiv.

In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma.

Wynn, T. Wynn, C. Karp, 1993, The Journal of clinical investigation.

Epitope mapping of monoclonal antibodies directed against lipophosphoglycan of Leishmania major promastigotes.

A. Bacic, D. Sacks, E. Handman, 1994, Molecular and biochemical parasitology.

Presentation of the Leishmania antigen LACK by infected macrophages is dependent upon the virulence of the phagocytosed parasites

N. Glaichenhaus, E. Mougneau, D. Sacks, 1999, European journal of immunology.

Memory may not need reminding

R. Seder, D. Sacks, 2004, Nature Medicine.

An analysis of T cell responsiveness in Indian kala-azar.

D. Sacks, F. Neva, J. Blackwell, 1987, Journal of immunology.

Tissue-resident macrophages as replicative niches for intracellular pathogens.

D. Sacks, S. H. Lee, 2017, Emerging topics in life sciences.

Vaccines Against Parasites

J. Bethony, N. Peters, D. Sacks, 2016 .

Increased Transmissibility of Leishmania donovani From the Mammalian Host to Vector Sand Flies After Multiple Exposures to Sand Fly Bites

M. Lewis, A. Paun, D. Sacks, 2017, The Journal of infectious diseases.

Development of infective stage Leishmania promastigotes within phlebotomine sand flies.

P. V. Perkins, D. Sacks, P. Perkins, 1985, The American journal of tropical medicine and hygiene.

Leishmania Priming of Human Dendritic Cells for CD40 Ligand-Induced Interleukin-12p70 Secretion Is Strain and Species Dependent

D. Sacks, M. Marovich, R. Lira, 2002, Infection and Immunity.

Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis

S. Sundar, D. Sacks, S. Nylén, 2007, The Journal of experimental medicine.

A novel role for the peritrophic matrix in protecting Leishmania from the hydrolytic activities of the sand fly midgut

M. Shahabuddin, G. Modi, D. Sacks, 1997, Parasitology.

Identification of an infective stage of Leishmania promastigotes.

P. V. Perkins, D. Sacks, P. Perkins, 1984, Science.

Leishmania major‐infected murine Langerhans cell‐like dendritic cells from susceptible mice release IL‐12 after infection and vaccinate against experimental cutaneous Leishmaniasis

Y. Belkaid, E. von Stebut, M. Udey, 2000, European journal of immunology.

Apoptotic cell clearance of Leishmania major-infected neutrophils by dendritic cells inhibits CD8+ T-cell priming in vitro by Mer tyrosine kinase-dependent signaling

A. Debrabant, N. Peters, D. Sacks, 2015, Cell Death and Disease.

IL-4- and IL-4 receptor-deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains.

W. Paul, D. Sacks, N. Noben-Trauth, 1999, Journal of immunology.

Parasite Substrains Leishmania major Mice Reveal Differences in Susceptibility to IL-4-and IL-4 Receptor-Deficient BALB / c

W. Paul, D. Sacks, N. Noben-Trauth, 1999 .

The Immune Response to Infection: Introduction

S. Kaufmann, B. Rouse, D. Sacks, 2011 .

Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection

S. Gurunathan, R. Seder, C. Prussin, 1998, Nature Medicine.

Inflammasomes and Leishmania: in good times or bad, in sickness or in health.

D. Zamboni, D. Sacks, 2019, Current opinion in microbiology.

Uninfected Mosquito Bites Confer Protection against Infection with Malaria Parasites

S. Kamhawi, M. Donovan, D. Sacks, 2007, Infection and Immunity.

IL-27 Regulates IL-10 and IL-17 from CD4+ Cells in Nonhealing Leishmania major Infection1

C. Hunter, D. Sacks, J. Stumhofer, 2009, The Journal of Immunology.

Infection Leishmania major Cells in Nonhealing + IL-27 Regulates IL-10 and IL-17 from CD 4 Hunter and

C. Hunter, D. Sacks, J. Stumhofer, 2009 .

Immune Intervention in Malaria

S. Kaufmann, B. Rouse, C. Long, 2011 .

Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9.

K. Joiner, D. Sacks, R. D. da Silva, 1990, Journal of immunology.

The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility to Leishmania major1

W. Paul, D. Sacks, N. Noben-Trauth, 2003, The Journal of Immunology.

Skin-derived macrophages from Leishmania major-susceptible mice exhibit interleukin-12- and interferon-gamma-independent nitric oxide production and parasite killing after treatment with immunostimulatory DNA.

Y. Belkaid, E. von Stebut, M. Udey, 2002, The Journal of investigative dermatology.

Drug Discovery for Kinetoplastid Diseases: Future Directions.

G. Dranoff, M. Barrett, J. Mottram, 2018, ACS infectious diseases.

Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes.

A. Sher, D. Sacks, S. Hieny, 1985, Journal of immunology.

Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment

A. Paun, D. Sacks, A. Romano, 2018, The Journal of experimental medicine.

Animal Models for the Analysis of Immune Responses to Leishmaniasis

P. Melby, D. Sacks, D. Sacks, 2001, Current protocols in immunology.

Animal models for the analysis of immune responses to leishmaniasis.

P. Melby, D. Sacks, D. Sacks, 2015, Current protocols in immunology.

Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor.

W. McMaster, B. Kelly, S. Kamhawi, 2002, Molecular and biochemical parasitology.

Growth cycle-dependent generation of complement-resistant Leishmania promastigotes.

E. Franke, P. McGreevy, D. Sacks, 1985, Journal of immunology.

Stage-specific adhesion of Leishmania promastigotes to the sandfly midgut.

P. V. Perkins, M. McConville, P. Lawyer, 1992, Science.

Divergent roles for Ly6C+CCR2+CX3CR1+ inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major

A. Paun, N. Peters, D. Sacks, 2017, PLoS pathogens.

Site-Dependent Recruitment of Inflammatory Cells Determines the Effective Dose of Leishmania major

N. Peters, D. Sacks, Nicole A. Doria, 2014, Infection and Immunity.

Efficient Capture of Infected Neutrophils by Dendritic Cells in the Skin Inhibits the Early Anti-Leishmania Response

A. Debrabant, N. Peters, D. Sacks, 2012, PLoS pathogens.

Re‐examination of the immunosuppressive mechanisms mediating non‐cure of Leishmania infection in mice

D. Sacks, C. Anderson, 2004, Immunological reviews.

LeishmaniasisResponses in Human Visceral IL-27 and IL-21 Are Associated with T Cell

R. Kumar, S. Sundar, D. Sacks, 2013 .

IL-27 and IL-21 Are Associated with T Cell IL-10 Responses in Human Visceral Leishmaniasis

R. Kumar, O. Singh, S. Sundar, 2011, The Journal of Immunology.

Expression of a stage-specific lipophosphoglycan in Leishmania major amastigotes.

D. Sacks, S. Turco, David L. Sacks, 1991, Molecular and biochemical parasitology.

Anti-Interleukin-10 Unleashes Transcriptional Response to Leishmanial Antigens in Visceral Leishmaniasis Patients.

R. Kumar, J. Blackwell, O. Singh, 2020, The Journal of infectious diseases.

Dichotomy in the tissue origin of schistosome acquired class I and class II major histocompatibility complex antigens

A. Sher, A. Simpson, A. Singer, 1984, The Journal of experimental medicine.

Identification of antigens recognized by T cells in human leishmaniasis: analysis of T-cell clones by immunoblotting

P. Melby, D. Sacks, D. Sacks, 1989, Infection and immunity.

Profile of human T cell response to leishmanial antigens. Analysis by immunoblotting.

P. Melby, D. Sacks, F. Neva, 1989, The Journal of clinical investigation.

Cutaneous leishmaniasis in anti-IgM-treated mice: enhanced resistance due to functional depletion of a B cell-dependent T cell involved in the suppressor pathway.

P. Scott, F. Sher, D. Sacks, 1984, Journal of immunology.

Conditions Influencing the Efficacy of Vaccination with Live Organisms against Leishmania major Infection

Y. Belkaid, S. Bertholet, K. Tabbara, 2005, Infection and Immunity.

Control of Leishmania-sand fly interactions by polymorphisms in lipophosphoglycan structure.

D. Sacks, S. Turco, 2003, Methods in Enzymology.

Vitro and In Vivo Antigen Processing-Independent Pathway In T Cells by a Transporter Associated with + Antigens Are Presented to CD 8 Leishmania

Carmen M. Collazo-Custodio, A. Sher, R. Goldszmid, 2006 .

The Null Hypothesis of IFN-γ and Monocyte Function in Leishmaniasis.

D. Sacks, 2020, Cell host & microbe.

Leishmania Specific CD4 T Cells Release IFNγ That Limits Parasite Replication in Patients with Visceral Leishmaniasis

R. Kumar, O. Singh, S. Sundar, 2014, PLoS neglected tropical diseases.

Leishmania–sand fly interactions controlling species‐specific vector competence

D. Sacks, D. Sacks, 2001, Cellular microbiology.

Leishmania donovani lipophosphoglycan selectively inhibits signal transduction in macrophages.

G. Matlashewski, D. Sacks, A. Descoteaux, 1991, Journal of immunology.

Metacyclogenesis in Leishmania promastigotes.

D. Sacks, 1989, Experimental parasitology.

Skin dendritic cells in murine cutaneous leishmaniasis.

Y. Belkaid, E. von Stebut, M. Udey, 2001, Immunobiology.

Trypanotolerance in inbred mice: an immunological basis for variation in susceptibility to infection with Trypanosoma brucei.

M. Selkirk, D. Sacks, 1980, Tropenmedizin und Parasitologie.

The Transcriptome of Leishmania major Developmental Stages in Their Natural Sand Fly Vector

Laura A. L. Dillon, N. El-Sayed, D. Sacks, 2017, mBio.

Leishmania Antigens Are Presented to CD8+ T Cells by a Transporter Associated with Antigen Processing-Independent Pathway In Vitro and In Vivo

Sylvie Bertholet, Farhat Afrin, Carmen M. Collazo-Custodio, 2006, The Journal of Immunology.

Evasion of innate immunity by parasitic protozoa

A. Sher, D. Sacks, 2002, Nature Immunology.

Demonstration of Genetic Exchange During Cyclical Development of Leishmania in the Sand Fly Vector

D. Dobson, S. Beverley, P. Lawyer, 2009, Science.

Comparison of the protein kinase and acid phosphatase activities of five species of Leishmania.

J. Lovelace, A. Saha, R. Glew, 1988, The Journal of protozoology.

Lipophosphoglycan masks recognition of the Leishmania donovani promastigote surface by human kala-azar serum.

C. Karp, D. Sacks, S. Turco, 1991, Journal of immunology.

Developmental modification of the lipophosphoglycan from Leishmania major promastigotes during metacyclogenesis.

D. Sacks, S. Turco, T. Brodin, 1990, Molecular and biochemical parasitology.

Complement binding by two developmental stages of Leishmania major promastigotes varying in expression of a surface lipophosphoglycan

K. Joiner, D. Sacks, R. D. da Silva, 1988, The Journal of experimental medicine.

Thermosensitivity patterns of Old vs. New World cutaneous strains of Leishmania growing within mouse peritoneal macrophages in vitro.

D. Sacks, F. Neva, A. Barral, 1983, The American journal of tropical medicine and hygiene.

The immunology of susceptibility and resistance to Leishmania major in mice

D. Sacks, N. Noben-Trauth, 2002, Nature Reviews Immunology.

The influence of early neutrophil-Leishmania interactions on the host immune response to infection

D. Sacks, F. Ribeiro-Gomes, 2012, Front. Cell. Inf. Microbio..

Vector Transmission of Leishmania Abrogates Vaccine-Induced Protective Immunity

S. Kamhawi, P. Lawyer, N. Peters, 2009, PLoS pathogens.

Toward a Defined Anti-Leishmania Vaccine Targeting Vector Antigens

Y. Belkaid, J. Ribeiro, S. Kamhawi, 2001, The Journal of experimental medicine.

A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes

C. Huynh, D. Sacks, N. Andrews, 2006, The Journal of experimental medicine.

Prevention and Treatment of Cutaneous Leishmaniasis in Primates by Using Synthetic Type D/A Oligodeoxynucleotides Expressing CpG Motifs

R. Seder, D. Sacks, D. Verthelyi, 2005, Infection and Immunity.

Indian kala-azar caused by Leishmania tropica

R. Kreutzer, D. Sacks, M. Sharma, 1995, The Lancet.

Vaccination with the Leishmania infantum Acidic Ribosomal P0 Protein plus CpG Oligodeoxynucleotides Induces Protection against Cutaneous Leishmaniasis in C57BL/6 Mice but Does Not Prevent Progressive Disease in BALB/c Mice

C. Alonso, D. Sacks, J. Carrión, 2005, Infection and Immunity.

Coinjection with CpG-Containing Immunostimulatory Oligodeoxynucleotides Reduces the Pathogenicity of a Live Vaccine against Cutaneous Leishmaniasis but Maintains Its Potency and Durability

Y. Belkaid, S. Bertholet, K. Tabbara, 2003, Infection and Immunity.

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

Y. Belkaid, E. Shevach, C. Piccirillo, 2002, Nature.

Vaccination with DNA Encoding the Immunodominant LACK Parasite Antigen Confers Protective Immunity to Mice Infected with Leishmania major

N. Glaichenhaus, S. Gurunathan, D. Brown, 1997, The Journal of experimental medicine.

A Natural Model of Leishmania major Infection Reveals a Prolonged “Silent” Phase of Parasite Amplification in the Skin Before the Onset of Lesion Formation and Immunity

Y. Belkaid, G. Milon, D. Sacks, 2000, The Journal of Immunology.

Epidemiologic Aspects of an Emerging Focus of Visceral Leishmaniasis in Tbilisi, Georgia

M. Fay, S. Kamhawi, D. Sacks, 2011, PLoS neglected tropical diseases.

Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani.

S. Sundar, D. Sacks, R. Lira, 1999, The Journal of infectious diseases.

Antigen Requirements for Efficient Priming of CD8+ T Cells by Leishmania major-Infected Dendritic Cells

Y. Belkaid, S. Bertholet, E. Caler, 2005, Infection and Immunity.

Molecular aspects of parasite-vector and vector-host interactions in leishmaniasis.

S. Kamhawi, D. Sacks, D Sacks, 2001, Annual review of microbiology.

Immunological and pathological evaluation of rhesus macaques infected with Leishmania major.

R. Seder, D. Sacks, B. Flynn, 2003, Experimental parasitology.

Protective immunity using recombinant human IL-12 and alum as adjuvants in a primate model of cutaneous leishmaniasis.

D. Sacks, J. Sypek, A. Gam, 1999, Journal of immunology.

Leishmania tropica: the identification and purification of metacyclic promastigotes and use in establishing mouse and hamster models of cutaneous and visceral disease.

C. Jaffe, D. Sacks, F. Neva, 1998, Experimental parasitology.

CD8+ T Cells Are Required for Primary Immunity in C57BL/6 Mice Following Low-Dose, Intradermal Challenge with Leishmania major

Y. Belkaid, S. Bertholet, E. Caler, 2002, The Journal of Immunology.

This information is current as Leishmania major Low-Dose , Intradermal Challenge with Immunity in C 57 BL / 6 Mice Following T Cells Are Required for Primary + CD 8 and

Y. Belkaid, S. Bertholet, E. Caler, 2002 .

Uptake of Leishmania major Amastigotes Results in Activation and Interleukin 12 Release from Murine Skin–derived Dendritic Cells: Implications for the Initiation of Anti-Leishmania Immunity

Yasmine Belkaid, Y. Belkaid, T. Jakob, 1998, The Journal of experimental medicine.

Host and parasite factors influencing the expression of cutaneous leishmaniasis.

A. Sher, P. Scott, D. Sacks, 1983, Ciba Foundation symposium.

Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum

Alexander T. Wenzel, W. Solbach, T. Laskay, 2006, Proceedings of the National Academy of Sciences.

Vaccination with Heat-killed Leishmania Antigen or Recombinant Leishmanial Protein and CpG Oligodeoxynucleotides Induces Long-Term Memory CD4+and CD8+T Cell Responses and Protection Against Leishmania major Infection

R. Coler, R. Seder, D. Klinman, 2002, The Journal of experimental medicine.

Combined Immune Therapy for the Treatment of Visceral Leishmaniasis

R. Kumar, S. Sundar, A. Haque, 2016, PLoS neglected tropical diseases.

Intrinsic immunosuppressive activity of different trypanosome strains varies with parasite virulence

M. Selkirk, D. Sacks, B. Askonas, 1980, Nature.

Evidence that the vectorial competence of phlebotomine sand flies for different species of Leishmania is controlled by structural polymorphisms in the surface lipophosphoglycan.

L. Garraway, S. Beverley, G. Modi, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Late metastatic Leishmaniasis in the mouse. A model for mucocutaneous disease.

D. Sacks, E. Petersen, F. Neva, 1983, The American journal of tropical medicine and hygiene.

CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages.

B. F. Hall, K. Joiner, D. Sacks, 1989, Journal of immunology.

Xenodiagnosis to evaluate the infectiousness of humans to sandflies in an area endemic for visceral leishmaniasis in Bihar, India: a transmission-dynamics study

M. Fay, O. Singh, S. Sundar, 2021, The Lancet. Microbe.

The role of phosphoglycans in Leishmania-sand fly interactions.

S. Beverley, G. Modi, D. Sacks, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Evaluation of Recombinant Leishmania Polyprotein Plus Glucopyranosyl Lipid A Stable Emulsion Vaccines against Sand Fly-Transmitted Leishmania major in C57BL/6 Mice

S. Bertholet, P. Lawyer, N. Peters, 2012, The Journal of Immunology.

C 57 BL / 6 Mice in Leishmania major Fly-Transmitted Stable Emulsion Vaccines against Sand Polyprotein Plus Glucopyranosyl Lipid A Leishmania Evaluation of Recombinant

S. Bertholet, P. Lawyer, N. Peters, 2012 .

CD4+CD25−Foxp3− Th1 cells are the source of IL-10–mediated immune suppression in chronic cutaneous leishmaniasis

D. Sacks, David Sacks, Vijay Kuchroo, 2007, The Journal of experimental medicine.

Intra-species and stage-specific polymorphisms in lipophosphoglycan structure control Leishmania donovani-sand fly interactions.

G. Modi, D. Sacks, S. Turco, 1999, Biochemistry.

The comparative fine structure and surface glycoconjugate expression of three life stages of Leishmania major.

D. Sacks, P. Pimenta, E. Saraiva, 1991, Experimental parasitology.

Stage-specific binding of Leishmania donovani to the sand fly vector midgut is regulated by conformational changes in the abundant surface lipophosphoglycan

M. McConville, D. Sacks, S. Turco, 1995, The Journal of experimental medicine.

Cell surface nanoanatomy of Leishmania major as revealed by fracture-flip. A surface meshwork of 44 nm fusiform filaments identifies infective developmental stage promastigotes.

D. Sacks, P. Pimenta, R. D. da Silva, 1989, European journal of cell biology.

The generation of infective stage Leishmania major promastigotes is associated with the cell-surface expression and release of a developmentally regulated glycolipid.

D. Sacks, R. D. da Silva, 1987, Journal of immunology.

IL-10 neutralization promotes parasite clearance in splenic aspirate cells from patients with visceral leishmaniasis.

R. Kumar, S. Sundar, D. Sacks, 2011, The Journal of infectious diseases.

Human visceral leishmaniasis is not associated with expansion or accumulation of Foxp3+ CD4 cells in blood or spleen.

Rajiv Kumar, S. Sundar, V. Prajapati, 2010, Parasite immunology.

Intracellular Replication-Deficient Leishmania donovani Induces Long Lasting Protective Immunity against Visceral Leishmaniasis

R. Dey, H. Nakhasi, R. Duncan, 2009, The Journal of Immunology.

Metacyclogenesis is a major determinant of Leishmania promastigote virulence and attenuation

D. Sacks, R. D. da Silva, Rosângela, 1987, Infection and immunity.

Interleukin 2 is an Upstream Regulator of CD4+ T Cells From Visceral Leishmaniasis Patients With Therapeutic Potential.

R. Kumar, O. Singh, S. Sundar, 2019, The Journal of infectious diseases.

Determinants for progression from asymptomatic infection to symptomatic visceral leishmaniasis: A cohort study

J. Blackwell, O. Singh, S. Sundar, 2019, PLoS neglected tropical diseases.

Splenic cytokine responses in Indian kala-azar before and after treatment.

S. Sundar, H. Murray, D. Sacks, 1998, The Journal of infectious diseases.

IL-10 and TGF-β Control the Establishment of Persistent and Transmissible Infections Produced by Leishmania tropica in C57BL/6 Mice

Y. Belkaid, Charles Anderson, T. Wynn, 2008, The Journal of Immunology.

CD8 T cell exhaustion in human visceral leishmaniasis.

R. Kumar, S. Sundar, D. Sacks, 2013, The Journal of infectious diseases.

Cutaneous Infection with Leishmania major Mediates Heterologous Protection against Visceral Infection with Leishmania infantum

N. Peters, D. Sacks, A. Romano, 2015, The Journal of Immunology.

Persistence Without Pathology in Phosphoglycan-Deficient Leishmania major

S. Beverley, D. Sacks, G. Späth, 2003, Science.

The Potency and Durability of DNA- and Protein-Based Vaccines Against Leishmania major Evaluated Using Low-Dose, Intradermal Challenge

Y. Belkaid, S. Gurunathan, R. Seder, 2001, The Journal of Immunology.

Requirements for the Maintenance of Th1 Immunity In Vivo Following DNA Vaccination: A Potential Immunoregulatory Role for CD8+ T Cells

John T. Chang, R. Locksley, N. Glaichenhaus, 2000, The Journal of Immunology.

Molecular mimicry of parasite antigens using anti-idiotypic antibodies.

D. Sacks, 1985, Current topics in microbiology and immunology.

Promastigotes Selectively Inhibit Interleukin 12 Induction in Bone Marrow-derived Macrophages from Susceptible and Resistant Mice

R. Badolato, Werner Müller, R. Gazzinelli, 1996 .

The immune response to infection

S. Kaufmann, B. Rouse, D. Sacks, 2011 .

Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies

M. Fay, J. Egen, S. Kamhawi, 2008, Proceedings of the National Academy of Sciences.

Immune privilege in sites of chronic infection: Leishmania and regulatory T cells

N. Peters, D. Sacks, 2006, Immunological reviews.

Phagosomes are competent organelles for antigen cross-presentation

Etienne Gagnon, Sylvie Bertholet, Pierre Thibault, 2003, Nature.

Establishing, Expanding, and Certifying a Closed Colony of Phlebotomus argentipes (Diptera: Psychodidae) for Xenodiagnostic Studies at the Kala Azar Medical Research Center, Muzaffarpur, Bihar, India

O. Singh, S. Sundar, P. Lawyer, 2017, Journal of Medical Entomology.

Molecular mimicry of a carbohydrate epitope on a major surface glycoprotein of Trypanosoma cruzi by using anti-idiotypic antibodies.

A. Sher, D. Sacks, L. Kirchhoff, 1985, Journal of immunology.

The vectorial competence of Phlebotomus sergenti is specific for Leishmania tropica and is controlled by species-specific, lipophosphoglycan-mediated midgut attachment

S. Kamhawi, G. Modi, D. Sacks, 2000, Parasitology.

The role of the lipophosphoglycan of Leishmania in vector competence

D. Sacks, S. Turco, E. Rowton, 1994, Parasitology.

Xenodiagnosis to address key questions in visceral leishmaniasis control and elimination

O. Singh, S. Sundar, M. Boelaert, 2020, PLoS neglected tropical diseases.

Changes in lipophosphoglycan and gene expression associated with the development of Leishmania major in Phlebotomus papatasi

G. Modi, D. Sacks, E. Rowton, 1995, Parasitology.

Evidence that schistosome MHC antigens are not synthesized by the parasite but are acquired from the host as intact glycoproteins.

A. Sher, T. McCutchan, A. Simpson, 1983, Journal of immunology.

Leishmania major: association of the differentially expressed gene B protein and the surface lipophosphoglycan as revealed by membrane capping.

D. Sacks, D. F. Smith, P. Pimenta, 1994, Experimental parasitology.

Alum-precipitated autoclaved Leishmania major plus bacille Calmette-Guérrin, a candidate vaccine for visceral leishmaniasis: safety, skin-delayed type hypersensitivity response and dose finding in healthy volunteers.

F. Modabber, P. Smith, F. Zicker, 2003, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Induction of immune responses with anti-idiotypic antibodies: Implications for the induction of protective immunity

G. Kelsoe, D. Sachs, D. Sacks, 2005, Springer Seminars in Immunopathology.

Protein methyltransferase 7 deficiency in Leishmania major increases neutrophil associated pathology in murine model

P. Volf, A. Cruz, D. Zamboni, 2021, PLoS neglected tropical diseases.

IL-10 and TGF-beta control the establishment of persistent and transmissible infections produced by Leishmania tropica in C57BL/6 mice.

Y. Belkaid, T. Wynn, S. Kamhawi, 2008, Journal of immunology.

The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge.

N. Glaichenhaus, S. Gurunathan, R. Seder, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites.

Damien Chaussabel, Mary Ann McDowell, D. Chaussabel, 2003, Blood.

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