D. Muruve

发表

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

P. Kubes, B. McDonald, K. Pittman, 2010, Science.

Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice

Subrata Ghosh, S. Hirota, P. Beck, 2016, Mediators of inflammation.

Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo.

T. Libermann, I. Stillman, D. Muruve, 1999, Human gene therapy.

The p53 Tumor Suppressor Is Stabilized by Inhibitor of Growth 1 (ING1) by Blocking Polyubiquitination

S. Richard, A. von Deimling, K. Riabowol, 2011, PloS one.

Serum Protein Signatures Using Aptamer-Based Proteomics for Minimal Change Disease and Membranous Nephropathy

H. Otu, T. Libermann, Handan Can, 2022, Kidney international reports.

A survey of patient perspectives on the research use of health information and biospecimens

Kiran Pohar Manhas, D. Muruve, S. Page, 2016, BMC medical ethics.

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

J. Tschopp, P. Ross, R. Parks, 2008, Nature.

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.

A. Lau, G. Armstrong, D. Philpott, 2018, Cell reports.

TLR9-dependent innate immune responses in the liver The genome of self-complementary AAV vectors increases

Brendan H. Lee, R. Herzog, I. Zolotukhin, 2012 .

The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver.

H. Ertl, Brendan H. Lee, R. Herzog, 2011, Blood.

The innate immune response to DNA.

D. Muruve, A. Vilaysane, Akosua Vilaysane, 2009, Seminars in immunology.

Antiviral Antibodies Target Adenovirus to Phagolysosomes and Amplify the Innate Immune Response1

J. Tschopp, P. Colarusso, D. Muruve, 2009, The Journal of Immunology.

Helper-Dependent Adenovirus Vectors Elicit Intact Innate but Attenuated Adaptive Host Immune Responses In Vivo

G. Maelandsmo, P. Ross, R. Parks, 2004, Journal of Virology.

Neutrophils Interact with Adenovirus Vectors via Fc Receptors and Complement Receptor 1

D. Muruve, M. J. Cotter, Anne-Kathrin Zaiss, 2005, Journal of Virology.

Differential Activation of Innate Immune Responses by Adenovirus and Adeno-Associated Virus Vectors

N. Wong, J. Bartlett, Qiang Liu, 2002, Journal of Virology.

The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. a ΔmucA mutant in anaerobic acidified nitrite sensitivity of planktonic and biofilm bacteria in vitro and during chronic murine lung infection

Boo Shan Tseng, L. Lu, Shengchang Su, 2019, PloS one.

Renal Effects of Peptic Ulcer Therapy

E. Burgess, D. Muruve, 1992, Drug safety.

PERITUBULAR CAPILLARY BASEMENT MEMBRANE REDUPLICATION IN ALLOGRAFTS AND NATIVE KIDNEY DISEASE: A Clinicopathologic Study of 278 Consecutive Renal Specimens

D. Miskulin, D. Muruve, I. Gedeon, 2001, Transplantation.

Isolation of neutrophils from mouse liver: A novel method to study effector leukocytes during inflammation.

D. Muruve, M. J. Cotter, 2006, Journal of immunological methods.

Increased urinary protein excretion in the "normal" range is associated with increased renin-angiotensin system activity.

B. Hemmelgarn, Sofia B. Ahmed, J. MacRae, 2012, American journal of physiology. Renal physiology.

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion.

H. Anders, O. Kulkarni, H. Liapis, 2013, The Journal of clinical investigation.

How Semantics Connotations May Influence Concerns About Donation of Biospecimens

L. Metz, D. Muruve, S. Page, 2020, Biopreservation and biobanking.

NLRP3 Localizes to the Tubular Epithelium in Human Kidney and Correlates With Outcome in IgA Nephropathy

M. James, B. Hemmelgarn, K. Trpkov, 2016, Scientific Reports.

Soluble fibronectin induces chemokine gene expression in renal tubular epithelial cells.

D. Muruve, S. Clark, L. Ren, 2005, Kidney international.

Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal injury.

G. Armstrong, T. Louie, D. Chung, 2010, Gastroenterology.

Cyclooxygenase-2 Inhibition Limits Angiotensin II-Induced DNA Oxidation and Protein Nitration in Humans

M. Poulin, B. Hemmelgarn, V. Pialoux, 2017, Front. Physiol..

Inflammasome-Independent NLRP3 Augments TGF-β Signaling in Kidney Epithelium

H. Duff, K. Trpkov, J. Chun, 2013, The Journal of Immunology.

The biobank for the molecular classification of kidney disease: research translation and precision medicine in nephrology

P. Ravani, D. Muruve, S. Page, 2017, BMC Nephrology.

Immune responses to adeno-associated virus vectors.

D. Muruve, A. Zaiss, 2005, Current gene therapy.

Ex vivo adenovirus-mediated gene delivery leads to long-term expression in pancreatic islet transplants.

T. Libermann, T. Strom, R. Manfro, 1997, Transplantation.

Adenovirus-mediated expression of Fas ligand induces hepatic apoptosis after Systemic administration and apoptosis of ex vivo-infected pancreatic islet allografts and isografts.

T. Libermann, V. Sukhatme, T. Strom, 1997, Human gene therapy.

Activation of neuronal P2X7 receptor-Pannexin-1 mediates death of enteric neurons during colitis

Roger J. Thompson, D. McKay, K. Sharkey, 2012, Nature Medicine.

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD.

A. Lau, H. Duff, C. Jenne, 2018, Journal of the American Society of Nephrology : JASN.

Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo.

G. Maelandsmo, P. Ross, R. Parks, 2004, Journal of virology.

The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

A. Lau, C. Perreault, P. Thibault, 2015, Science Translational Medicine.

Contrast-induced encephalopathy and seizures in a patient with chronic renal insufficiency.

T. Steinman, D. Muruve, 1996, Clinical nephrology.

Divergent roles of Toll‐like receptor 2 in response to lipoteichoic acid and Staphylococcus aureus in vivo

P. Kubes, Erin F. McAvoy, M. Ho, 2010, European journal of immunology.

Trends in Biopsy-Based Diagnosis of Kidney Disease: A Population Study

P. Ravani, A. Hildebrand, D. Muruve, 2018, Canadian journal of kidney health and disease.

Neutrophil Elastase Acts as a Biased Agonist for Proteinase-activated Receptor-2 (PAR2)*

M. Hollenberg, K. Mihara, C. Lau, 2011, The Journal of Biological Chemistry.

This information is current as Immune Response Phagolysosomes and Amplify the Innate Antiviral Antibodies Target Adenovirus to

J. Tschopp, P. Colarusso, D. Muruve, 2009 .

Anticoagulant Related Nephropathy Induced by Dabigatran

A. Box, D. Muruve, H. Benediktsson, 2018, Case reports in nephrology.

The characterization of alpha5-integrin expression on tubular epithelium during renal injury.

K. Trpkov, D. Muruve, L. Ren, 2007, American journal of physiology. Renal physiology.

Adenovirus Vector-Induced Expression of the C-X-C Chemokine IP-10 Is Mediated through Capsid-Dependent Activation of NF-κB

T. Libermann, N. Wong, D. Muruve, 2000, Journal of Virology.

AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria

Erin E. Gill, B. Aronow, D. Hassett, 2020, Proceedings of the National Academy of Sciences.

Akt/Protein Kinase B Activation by Adenovirus Vectors Contributes to NFκB-Dependent CXCL10 Expression

Qiang Liu, B. Winston, D. Muruve, 2005, Journal of Virology.

The induction of inflammation by adenovirus vectors used for gene therapy.

D. Muruve, M. J. Cotter, 2005, Frontiers in bioscience : a journal and virtual library.

Vitamin D3 Metabolites Enhance the NLRP3‐Dependent Secretion of IL‐1β From Human THP‐1 Monocytic Cells

P. Beck, D. Muruve, S. E. Tulk, 2015, Journal of cellular biochemistry.

Renal immune surveillance and dipeptidase‐1 contribute to contrast‐induced acute kidney injury

A. Lau, M. James, P. Kubes, 2018, The Journal of clinical investigation.

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

Yan Li, Subrata Ghosh, Ramnik J. Xavier, 2011, Inflammatory bowel diseases.

Pregnane X Receptor Activation Triggers Rapid ATP Release in Primed Macrophages That Mediates NLRP3 Inflammasome Activation

S. Mani, S. Hirota, D. Muruve, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Helper-Dependent Adenovirus Vectors Elicit Intact Innate but Attenuated Adaptive Host Immune Responses In Vivo

G. Maelandsmo, P. Ross, R. Parks, 2004, Journal of Virology.

Post-mortem molecular investigations of SARS-CoV-2 in an unexpected death of a recent kidney transplant recipient

B. McDonald, D. Pillai, J. Chun, 2021, American Journal of Transplantation.

Rituximab is a safe and effective long-term treatment for children with steroid and calcineurin inhibitor-dependent idiopathic nephrotic syndrome.

A. Edefonti, F. Scolari, P. Ravani, 2013, Kidney international.

Diabetes mellitus increases endothelin-1 gene transcription in rat kidney.

N. Wong, C. Whiteside, J. Dufresne, 2000, Kidney international.

MAP kinase activation increases BK polyomavirus replication and facilitates viral propagation in vitro.

P. Acott, P. Beck, D. Muruve, 2010, Journal of virological methods.

The Risk of Microscopic Colitis in Solid-Organ Transplantation Patients: A Population-Based Study

G. Kaplan, P. Beck, D. Muruve, 2008, Transplantation.

SARS-CoV-2 Shedding in Dialysis Patients With COVID-19

B. Berenger, J. Conly, J. MacRae, 2021, Kidney International Reports.

Morphometric and biological characterization of biofilm in tunneled hemodialysis catheters.

B. Hemmelgarn, S. M. Jones, P. Ravani, 2011, American journal of kidney diseases : the official journal of the National Kidney Foundation.

A case of aggressive atypical anti-GBM disease complicated by CMV pneumonitis

S. Nasr, M. Fritzler, D. Muruve, 2019, BMC Nephrology.

New Answers to Old Conundrums: What Antibodies, Exosomes and Inflammasomes Bring to the Conversation. Canadian National Transplant Research Program International Summit Report

T. Mohanakumar, R. Fairchild, C. Cairo, 2017, Transplantation.

Complement factor B gene regulation: synergistic effects of TNF-alpha and IFN-gamma in macrophages.

B. Winston, D. Muruve, P. M. Krein, 2002, Journal of immunology.

Peptide-Mediated PEGylation of Polysulfone Reduces Protein Adsorption and Leukocyte Activation

R. Irvin, D. Muruve, Elisabeth M. Davis, 2015, ASAIO journal.

Quantification of Inflammasome Adaptor Protein ASC in Biological Samples by Multiple-Reaction Monitoring Mass Spectrometry

A. Lau, D. Muruve, J. MacDonald, 2018, Inflammation.

A B1a–natural IgG–neutrophil axis is impaired in viral- and steroid-associated aspergillosis

B. McDonald, J. Biernaskie, D. Mahoney, 2022, Science Translational Medicine.

Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor–induced dipeptidase-1 expression and glutathione depletion

A. Lau, S. Bornstein, M. Hannani, 2022, Science advances.

Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver

A. Lau, P. Kubes, Erin F. McAvoy, 2019, Cell.

Aluminum absorption and excretion following sucralfate therapy in chronic renal insufficiency.

E. Burgess, D. Muruve, R. Audette, 1992, The American journal of medicine.

Interleukin-8 in gastrointestinal inflammation and malignancy: induction and clinical consequences

J. Cotton, A. Buret, P. Beck, 2016 .

NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways.

D. Muruve, J. Platnich, Jaye M. Platnich, 2019, Archives of biochemistry and biophysics.

Inflammasomes in the CNS

C. Power, D. Muruve, J. Walsh, 2014, Nature Reviews Neuroscience.

A peptide-based biological coating for enhanced corrosion resistance of titanium alloy biomaterials in chloride-containing fluids

D. Hassett, R. Irvin, D. Muruve, 2017, Journal of biomaterials applications.

Molecular basis of the inflammatory response to adenovirus vectors

Qiang Liu, D. Muruve, D A Muruve, 2003, Gene Therapy.

The inflammasome: a danger sensing complex triggering innate immunity.

J. Tschopp, C. Dostert, D. Muruve, 2007, Current opinion in immunology.

A Putative ABC Transporter Permease Is Necessary for Resistance to Acidified Nitrite and EDTA in Pseudomonas aeruginosa under Aerobic and Anaerobic Planktonic and Biofilm Conditions

Shengchang Su, D. Hassett, J. Lam, 2016, Front. Microbiol..

Use of a murine secreted alkaline phosphatase as a non‐immunogenic reporter gene in mice

M. Pavliv, F. Graham, G. Mælandsmo, 2005, The journal of gene medicine.

The innate immune response to adenovirus vectors.

D. Muruve, Daniel A Muruve, 2004, Human gene therapy.

Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity

Ping Zhang, Yan Shi, J. Tschopp, 2011, Nature Medicine.

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition.

C. Streutker, D. Philpott, S. Girardin, 2017, Cell reports.

Gasdermins and pyroptosis in the kidney

D. Muruve, E. Elías, Brayden Lyons, 2023, Nature Reviews Nephrology.

Anti-GBM Glomerulonephritis Involves IL-1 but Is Independent of NLRP3/ASC Inflammasome-Mediated Activation of Caspase-1

C. Cohen, H. Anders, O. Kulkarni, 2011, PloS one.

The inflammasomes in kidney disease.

H. Anders, D. Muruve, 2011, Journal of the American Society of Nephrology : JASN.

Mitochondrial NLRP3 Protein Induces Reactive Oxygen Species to Promote Smad Protein Signaling and Fibrosis Independent from the Inflammasome*

H. Duff, P. Fedak, J. Chun, 2014, The Journal of Biological Chemistry.

Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response.

T. Libermann, P. Oettgen, H. Perlman, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Proteinase-activated Receptor-2 Transactivation of Epidermal Growth Factor Receptor and Transforming Growth Factor-β Receptor Signaling Pathways Contributes to Renal Fibrosis*

M. Hollenberg, D. Muruve, R. Ramachandran, 2013, The Journal of Biological Chemistry.

Tissue-selective alternate promoters guide NLRP6 expression

Paul M. K. Gordon, A. Lau, S. Girardin, 2020, Life Science Alliance.

The role of inflammasomes in kidney disease

D. Muruve, Takanori Komada, 2019, Nature Reviews Nephrology.

Biochemical and structural aspects of the ATP‐binding domain in inflammasome‐forming human NLRP proteins

C. Wijekoon, D. Muruve, J. MacDonald, 2013, IUBMB life.

Immunity to adeno-associated virus vectors in animals and humans: a continued challenge

D. Muruve, A K Zaiss, D A Muruve, 2008, Gene Therapy.

Complement Is an Essential Component of the Immune Response to Adeno-Associated Virus Vectors

N. Wong, V. Holers, J. Bartlett, 2008, Journal of Virology.

Anti-BK Virus Mechanisms of Sirolimus and Leflunomide Alone and in Combination: Toward a New Therapy for BK Virus Infection

D. Muruve, Mark E. Seamone, A. Liacini, 2010, Transplantation.

Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis

M. Gale, V. Nerurkar, D. Muruve, 2013, Journal of Virology.

The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.

J. Tschopp, B. Hemmelgarn, K. Trpkov, 2010, Journal of the American Society of Nephrology : JASN.

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome.

Yan Li, Hanping Feng, J. Tschopp, 2010, Gastroenterology.

Nucleotide-Binding Oligomerization Domain-Like Receptors and Inflammasomes in the Pathogenesis of Non-Microbial Inflammation and Diseases

P. Beck, D. Muruve, D. R. Mason, 2011, Journal of Innate Immunity.

Epithelial Cell Extrusion Leads to Breaches in the Intestinal Epithelium

C. Sergi, P. Boulanger, K. Madsen, 2013, Inflammatory bowel diseases.

The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors.

P. Colarusso, T. Wickham, Qiang Liu, 2003, Human Gene Therapy.

Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk.

P. Stemkowski, D. Muruve, G. Zamponi, 2020, Cell reports.

Detecting Proteomic Indicators to Distinguish Diabetic Nephropathy from Hypertensive Nephrosclerosis by Integrating Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging with High-Mass Accuracy Mass Spectrometry

B. Heijs, F. Magni, P. V. van Veelen, 2020, Kidney and Blood Pressure Research.

Application of immobilized ATP to the study of NLRP inflammasomes.

Philip F. Hughes, T. Haystead, D. Muruve, 2019, Archives of biochemistry and biophysics.

Hierarchical regulation of wound healing by NOD-like receptors in cardiovascular disease.

H. Duff, D. Muruve, N. Bracey, 2015, Antioxidants & redox signaling.

The chemokine GRO-α (CXCL1) confers increased tumorigenicity to glioma cells

Yan Zhou, V. Yong, Qiang Liu, 2005 .

The chemokine GRO-alpha (CXCL1) confers increased tumorigenicity to glioma cells.

Yan Zhou, V. Yong, Qiang Liu, 2005, Carcinogenesis.

Oncolytic viruses as experimental treatments for malignant gliomas: using a scourge to treat a devil.

F. Zemp, P. Forsyth, D. Muruve, 2010, Cytokine & growth factor reviews.

Evidence of extensive diversity in bacterial adherence mechanisms that exploit unanticipated stainless steel surface structural complexity for biofilm formation.

R. Irvin, D. Muruve, Dongyang Li, 2013, Acta biomaterialia.

Activation of p38 and ERK Signaling during Adenovirus Vector Cell Entry Lead to Expression of the C-X-C Chemokine IP-10

M. Hollenberg, S. Robbins, T. Wickham, 2002, Journal of Virology.

Adenovirus vector-induced inflammation: capsid-dependent induction of the C-C chemokine RANTES requires NF-kappa B.

T. Libermann, N. Wong, D. Muruve, 2002, Human gene therapy.

The role of selectins and integrins in adenovirus vector‐induced neutrophil recruitment to the liver

P. Kubes, Yang Li, Samuel S. Lee, 2002, European journal of immunology.

Intrarectal Instillation of Clostridium difficile Toxin A Triggers Colonic Inflammation and Tissue Damage: Development of a Novel and Efficient Mouse Model of Clostridium difficile Toxin Exposure

Yan Li, G. Armstrong, T. Dingle, 2012, Infection and Immunity.

The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain

Henry J. Duff, Sergei Yu Noskov, Meruyert Kudaibergenova, 2019, Molecular Pharmacology.

Complement Factor B Gene Regulation: Synergistic Effects of TNF-α and IFN-γ in Macrophages1

B. Winston, D. Muruve, Yong Huang, 2002, The Journal of Immunology.

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin‐1β

H. Duff, J. Lees-Miller, S. Hirota, 2013, Experimental physiology.

Peptide-based biocoatings for corrosion protection of stainless steel biomaterial in a chloride solution.

D. Hassett, Y. F. Cheng, R. Irvin, 2016, Materials Science and Engineering C: Materials for Biological Applications.

Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome

J. Tschopp, K. Schroder, D. Muruve, 2009, Current Biology.

Sociodemographic associations with abnormal estimated glomerular filtration rate (eGFR) in a large Canadian city: a cross-sectional observation study

C. Naugler, D. Muruve, H. Benediktsson, 2018, BMC Nephrology.

Contributes to Renal Fibrosis Receptor Signaling Pathways β Factor-Factor Receptor and Transforming Growth Transactivation of Epidermal Growth Proteinase-activated Receptor-2 Molecular Bases of Disease :

M. Hollenberg, D. Muruve, R. Ramachandran, 2013 .

Reduced T-Dependent Humoral Immunity in CD20-Deficient Mice

D. Muruve, R. Sanyal, J. Deans, 2013, The Journal of Immunology.

Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury

A. Lau, S. Robbins, C. Jenne, 2022, Science advances.

Results C difficile TcdA and TcdB Trigger IL-1 Secretion and Caspase-1 Activation

G. Armstrong, H. Feng, O. Gross, 2022 .

A survey of patient perspectives on the research use of health information and biospecimens

D. Muruve, S. Page, K. P. Manhas, 2016, BMC medical ethics.

Quantification of Inflammasome Adaptor Protein ASC in Biological Samples by Multiple-Reaction Monitoring Mass Spectrometry

A. Lau, M. James, D. Muruve, 2018, Inflammation.

NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis

A. Lau, M. Stahl, M. Stahl, 2016, Cell Death and Differentiation.

Glucose regulates secretion of exogenously expressed insulin from HepG2 cells in vitro and in a mouse model of diabetes mellitus in vivo.

N. Wong, D. Muruve, I. Wanke, 2013, Journal of molecular endocrinology.

AIM2 Suppresses Inflammation and Epithelial Cell Proliferation during Glomerulonephritis.

A. Lau, J. Chun, D. Muruve, 2021, Journal of immunology.

Detection and Typing of Renal Amyloidosis by Fluorescence Spectroscopy Using the Environmentally Sensitive Fluorophore K114

P. Stys, D. Muruve, H. Benediktsson, 2022, Molecular Imaging and Biology.