A. G. de Boer

发表

Pharmacological investigations on lipopolysaccharide-induced permeability changes in the blood-brain barrier in vitro.

D. Breimer, P. Gaillard, A. G. de Boer, 2003, Microvascular research.

Mucoadhesive Polymers in Peroral Peptide Drug Delivery. II. Carbomer and Polycarbophil Are Potent Inhibitors of the Intestinal Proteolytic Enzyme Trypsin

Gerrit Borchard, Hans E. Junginger, H. Junginger, 1995, Pharmaceutical Research.

Bioadhesion by Means of Specific Binding of Tomato Lectin

Claus-Michael Lehr, Hans E. Junginger, H. Junginger, 1992, Pharmaceutical Research.

Mucoadhesive Polymers in Peroral Peptide Drug Delivery. VI. Carbomer and Chitosan Improve the Intestinal Absorption of the Peptide Drug Buserelin In Vivo

Hans E. Junginger, H. Junginger, A. G. de Boer, 1996, Pharmaceutical Research.

The transference of results between blood-brain barrier cell culture systems.

D. Breimer, P. Gaillard, A. G. de Boer, 1999, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug.

P. Gaillard, A. G. de Boer, A. Boer, 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Apoptin: therapeutic potential of an early sensor of carcinogenic transformation.

M. Noteborn, Ying-hui Zhang, P. Voskamp, 2008, Annual review of pharmacology and toxicology.

Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal caco-2 cell monolayers.

H. Junginger, M. Thanou, A. G. de Boer, 2000, Journal of controlled release : official journal of the Controlled Release Society.

In Vitro and in Vivo Transport of Zidovudine (AZT) Across the Blood–Brain Barrier and the Effect of Transport Inhibitors

U. Jaehde, D. Breimer, R. Masereeuw, 1994, Pharmaceutical Research.

Transport of Desglycinamide-Arginine Vasopressin Across the Blood–Brain Barrier in Rats as Evaluated by the Unit Impulse Response Methodology

D. Breimer, A. G. de Boer, J. Verhoef, 1990, Pharmaceutical Research.

Characterization and Modulation of the Transferrin Receptor on Brain Capillary Endothelial Cells

M. Danhof, D. Crommelin, A. G. de Boer, 2004, Pharmaceutical Research.

Targeting liposomes with protein drugs to the blood-brain barrier in vitro.

Meindert Danhof, Sanja Stevanović, M. Danhof, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Coupling of Metal Containing Homing Devices to Liposomes via a Maleimide Linker: Use of TCEP to Stabilize Thiol-groups without Scavenging Metals

M. Danhof, D. Crommelin, A. G. de Boer, 2004, Journal of drug targeting.

Validation of the Transferrin Receptor for Drug Targeting to Brain Capillary Endothelial Cells In Vitro

M. Danhof, D. Crommelin, P. Gaillard, 2004, Journal of drug targeting.

BBB Transport and P-glycoprotein Functionality Using MDR1A (-/-) and Wild-Type Mice. Total Brain Versus Microdialysis Concentration Profiles of Rhodamine-123

A. Schinkel, D. Breimer, A. G. de Boer, 1998, Pharmaceutical Research.

The Use of Intracerebral Microdialysis to Determine Changes in Blood-Brain Barrier Transport Characteristics

M. Danhof, D. Breimer, A. G. de Boer, 2004, Pharmaceutical Research.

The Use of Intracerebral Microdialysis for the Determination of Pharmacokinetic Profiles of Anticancer Drugs in Tumor-Bearing Rat Brain

M. Danhof, D. Breimer, A. G. de Boer, 1995, Pharmaceutical Research.

Drug targeting to the brain

G. Schenk, A. G. de Boer, J. Rip, 2008, Annual review of pharmacology and toxicology.

Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2).

H. Junginger, M. Thanou, A. G. de Boer, 1999, Journal of pharmaceutical sciences.

2B-Trans technology: targeted drug delivery across the blood-brain barrier.

P. Gaillard, A. G. de Boer, 2008, Methods in molecular biology.

Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood–brain barrier

D. Breimer, A. G. de Boer, I. C. J. van der Sandt, 2001, AIDS.

The role of drug transporters at the blood-brain barrier.

P. Gaillard, A. G. de Boer, I. C. J. van der Sandt, 2003, Annual review of pharmacology and toxicology.

Absorption Enhancement of Rectally Infused Cefoxitin Sodium by Medium-Chain Fatty Acids in Conscious Rats: Concentration–Effect Relationship

D. Breimer, A. G. de Boer, E. V. van Hoogdalem, 1988, Pharmaceutical Research.

Transport of a Hydrophilic Compound into the Cerebrospinal Fluid During Experimental Allergic Encephalomyelitis and After Lipopolysaccharide Administration

H. D. de Vries, T. V. van Berkel, J. Kuiper, 1995, Pharmaceutical Research.

Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).

H. Junginger, B. Boer, A. G. de Boer, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments.

H. Junginger, A. G. de Boer, A. F. Kotzé, 1999, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The role of P‐glycoprotein in blood‐brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (−/−) and mdr1a (+/+) mice

A. G. de Boer, M. Hammarlund-Udenaes, R. Xie, 1999, British journal of pharmacology.

Rectal Absorption Enhancement of Des-Enkephalin-γ-Endorphin (DEγE) by Medium-Chain Glycerides and EDTA in Conscious Rats

D. Breimer, A. G. de Boer, J. Verhoef, 2004, Pharmaceutical Research.

Evidence of P‐glycoprotein mediated apical to basolateral transport of flunisolide in human broncho‐tracheal epithelial cells (Calu‐3)

H. Junginger, G. Borchard, B. Florea, 2001, British journal of pharmacology.

P-Glycoprotein Inhibition Leads to Enhanced Disruptive Effects by Anti-Microtubule Cytostatics at the In Vitro Blood-Brain Barrier

D. Breimer, P. Gaillard, A. G. de Boer, 2001, Pharmaceutical Research.

Site Specific Rectal Drug Administration in Man with an Osmotic System: Influence on “First-Pass” Elimination of Lidocaine

D. Breimer, A. G. de Boer, L. D. de Leede, 1984, Pharmaceutical Research.

Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain.

J. DeJongh, M. Danhof, A. IJzerman, 2005, European journal of pharmacology.

Population pharmacokinetic-pharmacodynamic modelling of the anti-hyperalgesic effect of 5'deoxy-N6-cylopentyladenosine in the mononeuropathic rat.

J. DeJongh, M. Danhof, A. IJzerman, 2004, European journal of pharmacology.

Avoidance of “First-Pass” Elimination of Rectally Administered Propranolol in Relation to the Site of Absorption in Rats

D. Breimer, A. G. de Boer, L. D. de Leede, 1983, Pharmaceutical Research.

Targeted delivery across the blood–brain barrier

P. Gaillard, A. G. de Boer, C. Visser, 2005, Expert opinion on drug delivery.

Brain penetration of synthetic adenosine A1 receptor agonists in situ: role of the rENT1 nucleoside transporter and binding to blood constituents.

K. Read, M. Danhof, A. IJzerman, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Absorption Enhancement of Rectally Infused Insulin by Sodium Tauro-24,25-Dihydrofusidate (STDHF) in Rats

D. Breimer, A. G. de Boer, J. Verhoef, 1990, Pharmaceutical Research.

Stereoselective Transport of Baclofen Across the Blood–Brain Barrier in Rats as Determined by the Unit Impulse Response Methodology

M. Danhof, D. Breimer, A. G. de Boer, 1991, Pharmaceutical Research.

Blood-brain barrier transport of synthetic adenosine A1 receptor agonists in vitro: structure transport relationships.

A. Hersey, M. Danhof, A. IJzerman, 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Population Pharmacokinetic Modeling of Blood-Brain Barrier Transport of Synthetic Adenosine A1 Receptor Agonists

J. DeJongh, M. Danhof, A. IJzerman, 2004, Journal of Pharmacology and Experimental Therapeutics.

Blood–brain barrier dysfunction and recovery

P. Gaillard, A. G. de Boer, A. Boer, 2006, Journal of Neural Transmission.

Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: assessment of molecular weight dependence and demonstration of transport routes.

P. Artursson, L. Lazorova, A. G. de Boer, 1998, Journal of drug targeting.

Efficient CRM197-mediated drug targeting to monocytes.

B. Berkhout, P. C. Haasnoot, G. Schenk, 2012, Journal of controlled release : official journal of the Controlled Release Society.

A novel opportunity for targeted drug delivery to the brain.

P. Gaillard, A. G. de Boer, A. Boer, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Quantification and Visualization of the Transport of Octreotide, a Somatostatin Analogue, Across Monolayers of Cerebrovascular Endothelial Cells

U. Jaehde, D. Breimer, R. Masereeuw, 1994, Pharmaceutical Research.

Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: possible implications for the design of synthetic adenosine derivatives.

M. Danhof, A. IJzerman, A. G. de Boer, 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro

Gerrit Borchard, Hans E. Junginger, H. Junginger, 1996 .

Intestinal drug absorption enhancement: an overview.

D. Breimer, A. G. de Boer, A. D. De Boer, 1989, Pharmacology & therapeutics.