M. Fanger

P. Kang, H. Uehara, Dongwon Lee, 2020, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Use of bispecific antibodies in the therapy of tumors.

M. Fanger, P. Guyre, P. Morganelli, 1993, Cancer treatment and research.

Bispecific antibodies for targeted cellular cytotoxicity.

M. Fanger, P. Guyre, 1991, Trends in biotechnology.

Monoclonal antibodies to Fc receptors for IgG on human mononuclear phagocytes. Antibody characterization and induction of superoxide production in a monocyte cell line.

C. Anderson, R. Looney, M. Fanger, 1986, The Journal of biological chemistry.

Isolation and characterization of My23, a myeloid cell-derived antigen reactive with the monoclonal antibody AML-2-23.

C. Maliszewski, R. Graziano, M. Fanger, 1985, Journal of immunology.

Monoclonal antibodies to myeloid differentiation antigens: in vivo studies of three patients with acute myelogenous leukemia.

M. Fanger, E. Ball, G. Bernier, 1983, Blood.

Fc gamma R-mediated killing by eosinophils.

R. Graziano, R. Looney, M. Fanger, 1989, Journal of immunology.

The oligosaccharide units of rabbit immunoglobulin G. Multiple carbohydrate attachment sites.

D. Smyth, M. Fanger, 1972, The Biochemical journal.

(calcitriol): a morphologic, phenotypic, and functional analysis Differentiation of a human monocytic cell line by 1,25-dihydroxyvitamin D3

M. Fanger, E. Ball, P. Guyre, 2011 .

Differentiation of a human monocytic cell line by 1,25-dihydroxyvitamin D3 (calcitriol): a morphologic, phenotypic, and functional analysis

M. Fanger, E. Ball, P. Guyre, 1984 .

Differentiation of a human monocytic cell line by 1,25-dihydroxyvitamin D3 (calcitriol): a morphologic, phenotypic, and functional analysis.

M. Fanger, E. Ball, P. Guyre, 1984, Blood.

Glucocorticoid enhances gamma interferon effects on human monocyte antigen expression and ADCC.

M. Fanger, E. Ball, P. Guyre, 1986, Clinical and Experimental Immunology.

Direct stimulation of ADCC by cloned gamma interferon is not ablated by glucocorticoids: studies using a human monocyte-like cell line (U-937).

M. Fanger, P. Guyre, L. Shen, 1984, Molecular immunology.

Monoclonal antibodies reactive with small cell carcinoma of the lung.

R. Graziano, G. Sorenson, M. Fanger, 1984, Journal of the National Cancer Institute.

The expression of receptors for IgA on human monocytes and calcitriol-treated HL-60 cells.

C. Maliszewski, M. Fanger, L. Shen, 1985, Journal of immunology.

Comparison of the effects of 1,25‐dihydroxyvitamin D3 on T lymphocyte subpopulations

M. Fanger, B. Yirinec, W. Rigby, 1987, European journal of immunology.

Subpopulations of human peripheral granulocyes and monocytes express receptors for IgA.

M. Fanger, G. Bernier, L. Shen, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Studies on the human T-lymphocyte population - IV. The isolation of T-lymphocyte antigens from peripheral lymphocytes.

M. Fanger, F. L. Owen, 1976, Immunochemistry.

Studies on the human T lymphocyte population. III. Synthesis and release of the lymphocyte receptor for sheep red blood cells by stimulated human T lymphoblasts.

M. Fanger, F. L. Owen, 1975, Journal of immunology.

Studies on the human T-lymphocyte population. I. The development and characterization of a specific anti-human T-cell antibody.

M. Fanger, F. L. Owen, 1974, Journal of immunology.

Role of oxygen intermediates in cytotoxicity: Studies in chronic granulomatous disease

M. Fanger, E. R. Stiehm, R. Roberts, 1993, Inflammation.

Comparison of cytotoxic properties of neonatal and adult neutrophils and monocytes and enhancement by cytokines.

M. Fanger, E. R. Stiehm, N. Salman, 1994, Clinical and diagnostic laboratory immunology.

Bispecific antibodies and targeted cellular cytotoxicity.

D. Segal, M. Fanger, J. Romet-Lemonne, 1991, Immunology today.

The prevalence and distribution of macrophages bearing Fc gamma R I, Fc gamma R II, and Fc gamma R III in synovium.

P. Lydyard, B. Bröker, M. Fanger, 1990, Scandinavian journal of rheumatology.

1,25-Dihydroxyvitamin D3 induces a myelomonocytic phenotype with enhanced effector cell function in the HL-60 promyelocytic leukemia cell line.

M. Fanger, E. Ball, L. Shen, 1985, Molecular immunology.

Gamma interferon induces monocytoid differentiation in the HL-60 cell line.

C. Maliszewski, M. Fanger, E. Ball, 1984, The Journal of clinical investigation.

The expression and modulation of human myeloid-specific antigens during differentiation of the HL-60 cell line.

R. Graziano, M. Fanger, E. Ball, 1983, Blood.

Polymorphonuclear leukocyte function triggered through the high affinity Fc receptor for monomeric IgG.

M. Fanger, P. Guyre, L. Shen, 1987, Journal of immunology.

Cytofluorographic analysis of receptors for IgA on human polymorphonuclear cells and monocytes and the correlation of receptor expression with phagocytosis.

M. Fanger, L. Shen, S. N. Goldstine, 1983, Molecular immunology.

myeloid progenitor cells The effects of recombinant-DNA-derived interferons on the growth of

M. Fanger, E. Ball, P. Guyre, 2011 .

The effects of recombinant-DNA-derived interferons on the growth of myeloid progenitor cells.

M. Fanger, E. Ball, P. Guyre, 1985, Blood.

Synergy between IL-8 and GM-CSF in reproductive tract epithelial cell secretions promotes enhanced neutrophil chemotaxis.

S. Hussey, M. Fanger, S. Asin, 2004, Cellular immunology.

Secretory IgA antibodies synergize with IgG in promoting ADCC by human polymorphonuclear cells, monocytes, and lymphocytes.

M. Fanger, L. Shen, Lilian Shen, 1981, Cellular immunology.

Monoclonal antibodies identify three IgG Fc receptors in normal human central nervous system.

M. Fanger, N. Peress, H. Fleit, 1989, Clinical immunology and immunopathology.

phagocytosis of malignant non-Hodgkin's lymphoma Bispecific-armed, interferon gamma-primed macrophage-mediated

P. Wallace, R. Graziano, M. Fanger, 2011 .

A bispecific antibody, MDX-H210, was developed to target cytotoxic effector cells expressing Fcy receptor type I (Fc'yRI, CD64) to HER2lneu

P. Wallace, J. Fisher, T. Keler, 2006 .

Monoclonal antibodies to novel myeloid antigens reveal human neutrophil heterogeneity.

R. Graziano, M. Fanger, E. Ball, 1982, Proceedings of the National Academy of Sciences of the United States of America.

IgA-mediated effector function of HL-60 cells following treatment with calcitriol.

C. Maliszewski, M. Fanger, L. Shen, 1986, Molecular immunology.

Monoclonal antibodies that bind to distinct epitopes on Fc gamma RI are able to trigger receptor function.

R. Graziano, M. Fanger, B. A. Vance, 1989, Journal of immunology.

Monocytes and polymorphonuclear neutrophils of patients with streptococcal pharyngitis express increased numbers of type I IgG Fc receptors.

M. Fanger, P. Guyre, A. S. Campbell, 1990, The Journal of clinical investigation.

Monoclonal antibodies that bind to the My23 human myeloid cell surface molecule: epitope analysis and antigen modulation studies.

C. Maliszewski, J. Fisher, J. Currier, 1987, Molecular immunology.

The specificity of receptors for IgA on human peripheral polymorphonuclear cells and monocytes.

M. Fanger, G. Bernier, J. Pugh, 1981, Cellular immunology.

Functional comparison of the inductions of NADPH oxidase activity and Fcγ RI in IFNγ-treated U937 cells☆

M. Fanger, P. Guyre, L. C. Pfefferkorn, 1990 .

The expression of myeloid-specific antigens on myeloid leukemia cells: correlations with leukemia subclasses and implications for normal myeloid differentiation.

M. Fanger, E. Ball, 1983, Blood.

Biologicals & Immunologicals Bispecific antibodies for the treatment of tumours and infectious diseases

P. Wallace, M. Fanger, D. Drakeman, 1997 .

The functional properties of Fc gamma RI, II and III on myeloid cells: a comparative study of killing of erythrocytes and tumor cells mediated through the different Fc receptors.

R. Graziano, M. Fanger, L. Shen, 1989, Molecular immunology.

Monoclonal antibodies PMN 6, PMN 29, and PM-81 bind differently to glycolipids containing a sugar sequence occurring in lacto-N-fucopentaose III.

S. Hakomori, M. Fanger, E. Ball, 1984, Archives of biochemistry and biophysics.

Bispecific reagents for aids therapy

M. Fanger, P. Guyre, N. Dinces, 1997 .

Targeting HIV‐1 to FcγR on human phagocytes via bispecific antibodies reduces infectivity of HIV‐1 to T cells

M. Fanger, A. Howell, P. Guyre, 1994, Journal of leukocyte biology.

Studies on the human T-lymphocyte population - V. Isolation of T-lymphocyte antigens from human renal failure serum.

M. Fanger, G. Bernier, F. L. Owen, 1976, Immunochemistry.

The effect of cytokines on the expression and function of Fc receptors for IgG on human myeloid cells.

J. Collins, R. Graziano, M. Fanger, 1990, Molecular immunology.

Human monocyte-mediated cytotoxicity: the use of Ig-bearing hybridomas as target cells to detect trigger molecules on the monocyte cell surface.

R. Graziano, M. Fanger, 1987, Journal of immunology.

Characteristics and function of Fc receptors on human lymphocytes.

P. Lydyard, M. Fanger, 1982, Immunology.

Human B cells cannot be triggered to kill target cells through their FCγRII or FcϵRII receptors

P. Lydyard, K. Pulford, L. Mackenzie, 1991 .

Bispecific antibodies for the treatment of tumours and infectious diseases.

P. Wallace, M. Fanger, D. Drakeman, 1997, Expert opinion on investigational drugs.

Trifluoroacetylated Cytochrome c

M. Fanger, H. A. Harbury, 1965 .

Humanized mAb H22 binds the human high affinity Fc receptor for IgG (FcγRI), blocks phagocytosis, and modulates receptor expression

P. Wallace, J. Fisher, L. Vitale, 1997, Journal of leukocyte biology.

Pseudomonas cytochrome c. II. Effect of modification of the methionine residues.

T. P. Hettinger, M. Fanger, H. A. Harbury, 1967, Biochemistry.

The determination of glucosamine and galactosamine.

D. Smyth, M. Fanger, D. G. Smyth, 1970, Analytical biochemistry.

IFN-gamma is produced by polymorphonuclear neutrophils in human uterine endometrium and by cultured peripheral blood polymorphonuclear neutrophils.

J. Collins, M. Fanger, P. Guyre, 1998, Journal of immunology.

Evidence for T lymphocyte subpopulations in the rabbit.

M. Fanger, A. Stavitsky, A. Reese, 1974, Journal of immunology.

Human immunodeficiency virus type 1 infection of cells and tissues from the upper and lower human female reproductive tract

M. Fanger, A. Howell, J. Stern, 1997, Journal of virology.

The oligosaccharide units of rabbit immunoglobulin G. Asymmetric attachment of C2-oligosaccharide.

D. Smyth, M. Fanger, 1972, The Biochemical journal.

Subpopulations of human lymphocytes defined by 2 -microglobulin.

M. Fanger, G. Bernier, 1973, Journal of Immunology.

Synergy between IgG and monoclonal IgM antibodies in antibody-dependent cell cytotoxicity.

P. Lydyard, I. Roitt, M. Fanger, 1981, Journal of Immunology.

Synthesis of 2 -microglobulin by stimulated lymphocytes.

M. Fanger, G. Bernier, Michael W. Fanger, 1972, Journal of immunology.

Heteroantibody-mediated cytotoxicity: antibody to the high affinity Fc receptor for IgG mediates cytotoxicity by human monocytes that is enhanced by interferon-gamma and is not blocked by human IgG.

C. Anderson, M. Fanger, P. Guyre, 1986, Journal of immunology.

A unique antigen expressed on myeloid cells and acute leukemia blast cells defined by a monoclonal antibody.

R. Graziano, M. Fanger, E. Ball, 1983, Journal of immunology.

FcγRI blockade and modulation for immunotherapy

P. Wallace, T. Keler, M. Fanger, 1997, Cancer Immunology, Immunotherapy.

Role of Fc gamma receptors in cancer and infectious disease.

P. Wallace, M. Fanger, A. Howell, 1994, Journal of leukocyte biology.

Macrophage-targeted killing and vaccines.

M. Fanger, C. Guyre, 1998, Research in immunology.

FcγR-directed immunotherapies

P. Wallace, M. Fanger, C. Guyre, 1998 .

Effects of Menstrual Cycle Status and Gender on Human Neutrophil Phenotype

M. Fanger, C. Wira, Zheng Shen, 2007, American journal of reproductive immunology.

Initial trial of bispecific antibody-mediated immunotherapy of CD15-bearing tumors: cytotoxicity of human tumor cells using a bispecific antibody comprised of anti-CD15 (MoAb PM81) and anti-CD64/Fc gamma RI (MoAb 32).

J. Fisher, M. Fanger, E. Ball, 1992, Journal of hematotherapy.

Phase I Pilot Trial of the Bispecific Antibody MDXH210 (anti-Fc&ggr;RI X anti–HER-2/neu) in Patients Whose Prostate Cancer Overexpresses HER-2/neu

A. Schned, M. Ernstoff, P. Kaufman, 2001, Journal of immunotherapy.

Role of Fcγ receptors in cancer and infectious disease

P. Wallace, M. Fanger, A. Howell, 1994 .

Human immunodeficiency virus type 1 infection of human uterine epithelial cells: viral shedding and cell contact-mediated infectivity.

S. Mason, M. Fanger, S. Asin, 2003, The Journal of infectious diseases.

Bispecific-armed, interferon gamma-primed macrophage-mediated phagocytosis of malignant non-Hodgkin's lymphoma.

P. Wallace, A. Givan, R. Graziano, 1996, Blood.

Bispecific antibody-dependent cellular cytotoxicity of HER2/neu-overexpressing tumor cells by Fc gamma receptor type I-expressing effector cells.

P. Wallace, J. Fisher, T. Keler, 1997, Cancer research.

Cytotoxicity mediated by human Fc receptors for IgG.

R. Graziano, M. Fanger, P. Guyre, 1989, Immunology today.

Rabbit lymphocytes with receptors for IgM. I. The development of receptors on lymphocytes following intravenous injection of antigen.

M. Fanger, G. Bernier, R. E. Birch, 1979, Cellular immunology.

Receptors for IgA on human lymphocytes--I. detection and specificity.

P. Lydyard, M. Fanger, 1981, Molecular immunology.

Lymphocytes in the rabbit expressing receptors for the Fc portion of rabbit immunoglobulin.

M. Fanger, G. Bernier, R. E. Birch, 1978, Journal of immunology.

Complement receptor lymphocytes in the rabbit I. an SIg-negative subpopulation in the appendix.

M. Fanger, W. Green, 1976, Journal of immunology.

Fcγ receptors in cancer and infectious disease

M. Fanger, D. Erbe, 1992 .

Mechanisms of Acute Toxicity in NKG2D Chimeric Antigen Receptor T Cell–Treated Mice

Ming-Ru Wu, G. Dranoff, W. Cook, 2016, The Journal of Immunology.

In vitro demonstration of two antigenically-distinct rabbit lymphocyte populations.

M. Fanger, A. Reese, R. Pelley, 1972, Journal of immunology.

Neuraminidase augments Fc gamma receptor II-mediated antibody-dependent enhancement of dengue virus infection.

F. Ennis, I. Kurane, M. Fanger, 1993, The Journal of general virology.

Bispecific antibody-targeted phagocytosis of HER-2/neu expressing tumor cells by myeloid cells activated in vivo.

P. Wallace, A. Givan, M. Waugh, 2001, Journal of immunological methods.

Fc gamma RI and Fc gamma RII on monocytes and granulocytes are cytotoxic trigger molecules for tumor cells.

R. Graziano, M. Fanger, 1987, Journal of immunology.

Lysis of small cell carcinoma of the lung (SCCL) cells by cytokine-activated monocytes and natural killer cells in the presence of bispecific immunoconjugates containing a gastrin-releasing peptide (GRP) analog or a GRP antagonist.

M. Fanger, E. Ball, M. Mokotoff, 1995, Journal of hematotherapy.

Expression of Receptors for IgA in Hairy‐Cell and Other B‐Cell Leukaemias

P. Lydyard, M. Fanger, C. Worman, 1981, British journal of haematology.

Colocalization of FcγRI-Targeted Antigen With Class I MHC: Implications for Antigen Processing1

M. Fanger, S. Swink, C. Guyre, 2001, The Journal of Immunology.

Processing With Class I MHC : Implications for Antigen RI-Targeted Antigen γ Colocalization of Fc

M. Fanger, S. Swink, C. Guyre, 2001 .

Receptors for IgA on rabbit lymphocytes. I. Distribution, specificity, and modulation.

M. Fanger, H. A. Stafford, 1980, Journal of Immunology.

Construction and characterization of a humanized anti-gamma-Ig receptor type I (Fc gamma RI) monoclonal antibody.

T. Keler, R. Graziano, M. Fanger, 1995, Journal of immunology.

HIV-1-infected monocytes and monocyte-derived macrophages are impaired in their ability to produce Superoxide radicals

P. Wallace, M. Fanger, A. Howell, 1997, International journal of clinical & laboratory research.

Inhibition of biological activity of mouse beta-nerve growth factor by monoclonal antibody.

K. Neet, M. Fanger, S. L. Warren, 1980, Science.

Differential regulation of neutrophil chemotaxis to IL‐8 and fMLP by GM‐CSF: lack of direct effect of oestradiol

S. Hussey, M. Fanger, C. Wira, 2006, Immunology.

Receptors for IgM on human lymphocytes. I. Detection of receptors on freshly drawn lymphocytes and at physiological temperature.

P. Lydyard, M. Fanger, 1979, Journal of immunological methods.

BIOS Instant Notes in Immunology

Michael W. Fanger, Peter M. Lydyard, Alex Whelan, 2004 .

Pharmacokinetic-pharmacodynamic relationships of the bispecific antibody MDX-H210 when administered in combination with interferon gamma: a multiple-dose phase-I study in patients with advanced cancer which overexpresses HER-2/neu.

P. Wallace, M. Waugh, J. Fisher, 2001, Journal of immunological methods.

Receptor Modulation by FcγRI-Specific Fusion Proteins Is Dependent on Receptor Number and Modified by IgG1

L. Vitale, T. Keler, R. Graziano, 2001, The Journal of Immunology.

Cross-linkage in lymphocyte transformation.

M. Fanger, 1972, Immunological Communications.

My 43, a monoclonal antibody that reacts with human myeloid cells inhibits monocyte IgA binding and triggers function.

M. Fanger, L. Shen, R. Lasser, 1989, Journal of immunology.

Studies on the human T-lymphocyte population. II. The use of a T-cell specific antibody in the partial isolation and characterization of the human lymphocyte receptor for sheep red blood cells.

M. Fanger, F. L. Owen, 1974, Journal of immunology.

Structural and biosynthetic studies of a human IgA half molecule.

C. Johnson, M. Fanger, G. Bernier, 1977, Journal of immunology.

Plasma Cell Leukemia with Excretion of Half-Molecules of Immunoglobulin A (α1 λ1)

M. Fanger, G. Bernier, J. H. Berman, 1977 .

Plasma cell leukemia with excretion of half-molecules of immunoglobulin A (alpha1 lambda1).

M. Fanger, G. Bernier, J. H. Berman, 1977, Annals of internal medicine.

FcγR in Cytotoxicity Exerted by Mononuclear Cells (Part 1 of 2)

R. Graziano, M. Fanger, P. Guyre, 1989 .

FcγR in Cytotoxicity Exerted by Mononuclear Cells (Part 2 of 2)

R. Graziano, M. Fanger, P. Guyre, 1989 .

[16] Derivation of monoclonal antibody to nerve growth factor

K. Neet, M. Fanger, T. J. Baribault, 1987 .

Anti-body-dependent cellular cytotoxicity (ADCC) function of peripheral blood polymorphonuclear neutrophils (PMN) after autologous bone marrow transplantation (ABMT).

M. Fanger, S. Ericson, L. Mills, 1995, Bone Marrow Transplantation.

Fc gamma R in cytotoxicity exerted by mononuclear cells.

R. Graziano, M. Fanger, P. Guyre, 1989, Chemical Immunology.

Beta 2-microglobulin enhances human lymphocyte surface receptor expression for IgG.

M. Fanger, G. Bernier, R. Birch, 1979, Journal of immunology.

Monocyte- and neutrophil-mediated lysis of SCCL by a bispecific molecule comprised of Lys3-BN and mAb22

M. Fanger, E. Ball, M. Mokotoff, 1995 .

Monoclonal antibody 197 (anti-Fc gamma RI) infusion in a patient with immune thrombocytopenia purpura (ITP) results in down-modulation of Fc gamma RI on circulating monocytes.

M. Fanger, P. Guyre, K. Wardwell, 1996, British Journal of Haematology.

Receptors for IgM on human lymphocytes. II. Mitogen-induced modulation of receptor expression.

P. Lydyard, M. Fanger, 1979, Clinical and experimental immunology.

Instant Notes Immunology

P. Lydyard, M. Fanger, A. Whelan, 1999 .

Going both ways: bispecific antibodies and targeted cellular cytotoxicity

D. Segal, J. Wunderlich, M. Fanger, 1990, The FASEB Journal.

Production of macrophage-activated killer cells for targeting of glioblastoma cells with bispecific antibody to FcγRI and the epidermal growth factor receptor

P. Wallace, C. Fadul, M. Fanger, 2000, Cancer Immunology, Immunotherapy.