P. Kanellakis

发表

Toll‐Like Receptor (TLR)4 and MyD88 are Essential for Atheroprotection by Peritoneal B1a B Cells

K. Peter, P. Tipping, H. Hosseini, 2016, Journal of the American Heart Association.

B1a B Lymphocytes Are Atheroprotective by Secreting Natural IgM That Increases IgM Deposits and Reduces Necrotic Cores in Atherosclerotic Lesions

P. Tipping, A. Agrotis, B. Toh, 2011, Circulation research.

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

P. Tipping, H. Hosseini, B. Toh, 2012, PloS one.

Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets

K. Peter, C. Hagemeyer, P. Kanellakis, 2016, Scientific Reports.

Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice

M. Febbraio, G. Lancaster, C. Bruce, 2011, Diabetologia.

Cytotoxic and Proinflammatory CD 8 + T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in ApoE-/-Mice Running title :

P. Tipping, H. Hosseini, B. Toh, 2013 .

Cytotoxic and Proinflammatory CD8+ T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in ApoE-Deficient Mice

P. Tipping, H. Hosseini, B. Toh, 2013, Circulation.

Role of bone-marrow- and non-bone-marrow-derived receptor for advanced glycation end-products (RAGE) in a mouse model of diabetes-associated atherosclerosis.

Merlin C. Thomas, A. Murphy, Merlin C Thomas, 2014, Clinical science.

Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms.

K. Peter, A. Kallies, B. Toh, 2020, European heart journal.

Acute myeloid leukemia maturation lineage influences residual disease and relapse following differentiation therapy

A. Perkins, R. Dickins, M. Hickey, 2021, Nature Communications.

Inhibition of protein tyrosine kinases attenuates increases in expression of transforming growth factor-beta isoforms and their receptors following arterial injury.

M. Ward, G. Jennings, R. Dilley, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: role of activated macrophages and cytokines.

N. Kalinina, A. Agrotis, P. Kanellakis, 2004, Arteriosclerosis, thrombosis, and vascular biology.

A CD1d-dependent lipid antagonist to NKT cells ameliorates atherosclerosis in ApoE-/- mice by reducing lesion necrosis and inflammation.

P. Tipping, H. Hosseini, B. Toh, 2016, Cardiovascular research.

Lesions : Role of Activated Macrophages and Cytokines Increased Expression of the DNA-Binding Cytokine HMGB 1 in Human Atherosclerotic

N. Kalinina, A. Agrotis, P. Kanellakis, 2004 .

Increased Expression of the DNA-Binding Cytokine HMGB1 in Human Atherosclerotic Lesions: Role of Activated Macrophages and Cytokines

N. Kalinina, A. Agrotis, P. Kanellakis, 2004 .

Follicular B Cells Promote Atherosclerosis via T Cell–Mediated Differentiation Into Plasma Cells and Secreting Pathogenic Immunoglobulin G

P. Tipping, A. Kallies, H. Hosseini, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Response to balloon injury is vascular bed specific: a consequence of de novo vessel structure?

M. Ward, G. Jennings, P. Kanellakis, 2000, Atherosclerosis.

Blood flow regulates the development of vascular hypertrophy, smooth muscle cell proliferation, and endothelial cell nitric oxide synthase in hypertension.

A. Agrotis, P. Kanellakis, A. Bobik, 2000, Hypertension.

Granulocyte colony-stimulating factor and stem cell factor improve endogenous repair after myocardial infarction.

Xiaojun Du, P. Kanellakis, A. Bobik, 2006, Cardiovascular research.

Hematopoietic Cell–Restricted Deletion of CD36 Reduces High-Fat Diet–Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue

M. Febbraio, A. Bonen, M. Watt, 2011, Diabetes.

Darbepoetin‐mediated cardioprotection after myocardial infarction involves multiple mechanisms independent of erythropoietin receptor–common β‐chain heteroreceptor

Xiao-Ming Gao, Xiaojun Du, A. Agrotis, 2010, British journal of pharmacology.

Activation Transcription Factor-4 Induced by Fibroblast Growth Factor-2 Regulates Vascular Endothelial Growth Factor-A Transcription in Vascular Smooth Muscle Cells and Mediates Intimal Thickening in Rat Arteries Following Balloon Injury

L. Khachigian, P. Kanellakis, A. Bobik, 2008, Circulation research.

CD4+ Natural Killer T Cells Potently Augment Aortic Root Atherosclerosis by Perforin- and Granzyme B-Dependent Cytotoxicity

P. Tipping, M. Smyth, H. Hosseini, 2015, Circulation research.

And Inhibit Allergic Airway Inflammation Modify Pulmonary Dendritic Cell Function Inert 50-nm Polystyrene Nanoparticles That

R. O’Hehir, M. Plebanski, Jun Yao, 2022 .

Anti‐TIM‐1 Monoclonal Antibody (RMT1‐10) Attenuates Atherosclerosis By Expanding IgM‐producing B1a Cells

K. Peter, H. Hosseini, B. Toh, 2018, Journal of the American Heart Association.

B-cell-specific depletion of tumour necrosis factor alpha inhibits atherosclerosis development and plaque vulnerability to rupture by reducing cell death and inflammation.

K. Peter, P. Tipping, H. Hosseini, 2016, Cardiovascular research.

Cytokine Therapy With Interleukin-2/Anti–Interleukin-2 Monoclonal Antibody Complexes Expands CD4+CD25+Foxp3+ Regulatory T Cells and Attenuates Development and Progression of Atherosclerosis

P. Tipping, A. Agrotis, B. Toh, 2012, Circulation.

Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats

M. Black, P. Kanellakis, A. Bobik, 1997, Journal of hypertension.

Cytokine Therapy with IL-2/anti-IL-2mAb Complexes Expands CD4+CD25+Foxp3+ Regulatory T Cells and Attenuates Development and of Developed Atherosclerosis

P. Tipping, A. Agrotis, B. Toh, 2012 .

Yin Yang‐1 Inhibits Intimal Thickening by Repressing p21WAF1/Cip1 Transcription and p21WAF1/Cip1‐Cdk4‐Cyclin D1 Assembly

L. Khachigian, P. Kanellakis, A. Bobik, 2007 .

Crosstalk between cytotoxic CD8+ T cells and stressed cardiomyocytes triggers development of interstitial cardiac fibrosis in hypertensive mouse hearts

K. Peter, B. Toh, P. Kanellakis, 2022, Frontiers in Immunology.

Natural killer (NK) cells augment atherosclerosis by cytotoxic-dependent mechanisms.

P. Tipping, B. Toh, P. Kanellakis, 2014, Cardiovascular research.

BAFF Receptor mAb Treatment Ameliorates Development and Progression of Atherosclerosis in Hyperlipidemic ApoE−/− Mice

P. Tipping, A. Rolink, H. Hosseini, 2013, PloS one.

Infusion of Reconstituted High-Density Lipoprotein Leads to Acute Changes in Human Atherosclerotic Plaque

D. Sviridov, A. Murphy, A. Dart, 2008, Circulation research.

Inert 50-nm Polystyrene Nanoparticles That Modify Pulmonary Dendritic Cell Function and Inhibit Allergic Airway Inflammation

Gabrielle T. Belz, Magdalena Plebanski, G. Belz, 2012, The Journal of Immunology.

Yin Yang-1 Inhibits Vascular Smooth Muscle Cell Growth and Intimal Thickening by Repressing p21WAF1/Cip1 Transcription and p21WAF1/Cip1-Cdk4-Cyclin D1 Assembly

L. Khachigian, P. Kanellakis, A. Bobik, 2007, Circulation research.

A pro-fibrotic role for interleukin-4 in cardiac pressure overload.

P. Kanellakis, A. Bobik, G. Kostolias, 2012, Cardiovascular research.

High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice

K. Peter, M. Nishibori, I. Ahrens, 2011, Arteriosclerosis, thrombosis, and vascular biology.

B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis

H. Hosseini, B. Toh, P. Kanellakis, 2020, Frontiers in Immunology.

CD4+CD25+Foxp3+ regulatory T cells suppress cardiac fibrosis in the hypertensive heart

A. Agrotis, P. Kanellakis, A. Bobik, 2011, Journal of hypertension.

Tranilast Prevents Activation of Transforming Growth Factor-&bgr; System, Leukocyte Accumulation, and Neointimal Growth in Porcine Coronary Arteries After Stenting

M. Ward, G. Jennings, A. Agrotis, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Distinct patterns of transforming growth factor-beta isoform and receptor expression in human atherosclerotic lesions. Colocalization implicates TGF-beta in fibrofatty lesion development.

M. Condron, R. Dilley, A. Agrotis, 1999, Circulation.

Differential roles of cardiac and leukocyte derived macrophage migration inhibitory factor in inflammatory responses and cardiac remodelling post myocardial infarction.

R. Bucala, A. Dart, E. Morand, 2014, Journal of molecular and cellular cardiology.

inhibitoryfactorininflammatoryresponsesandcardiacremodellingpost myocardial infarction

R. Bucala, A. Dart, Xiao-Ming Gao, 2014 .

Phosphatidylserine liposomes mimic apoptotic cells to attenuate atherosclerosis by expanding polyreactive IgM producing B1a lymphocytes.

P. Tipping, H. Hosseini, B. Toh, 2015, Cardiovascular research.

Angioplasty-induced superoxide anions and neointimal hyperplasia in the rabbit carotid artery: suppression by the isoflavone trans-tetrahydrodaidzein.

P. Nestel, P. Kanellakis, A. Bobik, 2004, Atherosclerosis.

Cytochrome b558—Dependent NAD(P)H Oxidase—Phox Units in Smooth Muscle and Macrophages of Atherosclerotic Lesions

N. Kalinina, A. Agrotis, P. Kanellakis, 2002, Arteriosclerosis, thrombosis, and vascular biology.

DEVELOPMENTALLY REGULATED TRANSFORMING GROWTH FACTOR‐β1 ACTION ON VASCULAR SMOOTH MUSCLE GROWTH IN THE SHR

A. Agrotis, P. Kanellakis, A. Bobik, 1994, Clinical and experimental pharmacology & physiology.

Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques

K. Peter, J. Mcfadyen, H. Hosseini, 2021, Thrombosis and Haemostasis.

Quantitative proteomic landscape of unstable atherosclerosis identifies molecular signatures and therapeutic targets for plaque stabilization

A. Vlahou, K. Peter, M. Makridakis, 2023, Communications Biology.

Eplerenone Suppresses Constrictive Remodeling and Collagen Accumulation After Angioplasty in Porcine Coronary Arteries

M. Ward, J. Funder, P. Kanellakis, 2001, Circulation.

Inhibition of Fibroblast Growth Factor Receptor Signaling Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice

G. Jennings, A. Agrotis, P. Kanellakis, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Chronic angiotensin II type 1 receptor antagonism in genetic hypertension: effects on vascular structure and reactivity

R. Dilley, P. Kanellakis, A. Bobik, 1993, Journal of hypertension.

Human Atherosclerotic Lesions : Colocalization Implicates TGF-Isoform and Receptor Expression in β Distinct Patterns of Transforming Growth Factor

M. Condron, R. Dilley, A. Agrotis, 1999 .

Colchicine exerts anti‐atherosclerotic and ‑plaque‐stabilizing effects targeting foam cell formation

M. Snel, P. Psaltis, P. Kanellakis, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Sympatho-adrenal mechanisms regulating cardiovascular hypertrophy in primary hypertension: a role for rilmenidine?

R. Dilley, P. Kanellakis, A. Bobik, 1998, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

Raised Soluble P-Selectin Moderately Accelerates Atherosclerotic Plaque Progression

K. Andrews, L. Fang, J. Chin-Dusting, 2014, PloS one.

A novel antioxidant 3,7-dihydroxy-isoflav-3-ene (DHIF) inhibits neointimal hyperplasia after vessel injury attenuating reactive oxygen species and nuclear factor-kappaB signaling.

A. Husband, P. Nestel, A. Agrotis, 2009, Atherosclerosis.

Vascular hypertrophy in renal hypertensive spontaneously hypertensive rats.

R. Dilley, P. Kanellakis, A. Bobik, 1994, Hypertension.

Scientific Contributions Vascular Hypertrophy in Renal Hypertensive Spontaneously Hypertensive Rats

R. Dilley, P. Kanellakis, A. Bobik, 2005 .

Thrombosis and Haemostasis Pharmacological inhibition of Factor XIIa attenuates abdominal aortic an- eurysm, reduces atherosclerosis, and stabilizes atherosclerotic plaques

J. Mcfadyen, P. Kanellakis, A. Bobik, 2021 .

Proliferation of Neointimal Smooth Muscle Cells after Arterial Injury

G. Jennings, R. Hannan, A. Agrotis, 2004, Journal of Biological Chemistry.

CD4+CD25+Foxp3+ regulatory T cells suppress cardiac fibrosis in the hypertensive heart

A. Agrotis, P. Kanellakis, A. Bobik, 2011, Journal of hypertension.

Cytokine Therapy With Interleukin-2/Anti–Interleukin-2 Monoclonal Antibody Complexes Expands CD4+CD25+Foxp3+ Regulatory T Cells and Attenuates Development and Progression of Atherosclerosis

P. Tipping, A. Agrotis, B. Toh, 2012, Circulation.

Cytokine Therapy With Interleukin-2/Anti–Interleukin-2 Monoclonal Antibody Complexes Expands CD4 (cid:1) CD25 (cid:1) Foxp3 (cid:1) Regulatory T Cells and Attenuates Development and Progression of Atherosclerosis

A. Agrotis, P. Kanellakis, T. Kyaw, 2012 .

B1a B Lymphocytes Are Atheroprotective by Secreting Natural IgM That Increases IgM Deposits and Reduces Necrotic Cores in Atherosclerotic Lesions

P. Tipping, A. Agrotis, B. Toh, 2011, Circulation research.

Cytotoxic and Proinflammatory Cd8 + T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in Apoe -/-mice

P. Tipping, H. Hosseini, B. Toh, 2022 .