B. Cross

发表

The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling.

P. Walter, L. Glimcher, E. Fiebiger, 2013, Cell host & microbe.

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

R. Silverman, J. Goodman, B. Jha, 2012, Proceedings of the National Academy of Sciences.

CRISPR: A Screener’s Guide

S. Lawo, C. le Sage, B. Cross, 2019, SLAS discovery : advancing life sciences R & D.

Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum

S. High, Cornelia M. Wilson, M. Pool, 2009, Journal of Cell Science.

The oligomeric state of Derlin-1 is modulated by endoplasmic reticulum stress

S. High, Cornelia M. Wilson, B. Cross, 2007, Molecular membrane biology.

New twists in the unfolded protein response

D. Ron, B. Cross, 2012, eLife.

New twists in the unfolded protein response The response of S. pombe, also known as fission yeast, to misfolded proteins involves mechanisms that have not been observed in other species.

D. Ron, B. Cross, J. Zheng, 2012 .

Establishing a flow process to coumarin-8-carbaldehydes as important synthetic scaffolds.

Ian R Baxendale, I. Baxendale, D. Ron, 2012, Chemistry.

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

S. Lawo, C. le Sage, N. McCarthy, 2017, Scientific Reports.

Increasing the performance of pooled CRISPR–Cas9 drop-out screening

Jonathan D. Moore, Benedict C. S. Cross, Steffen Lawo, 2016, Scientific Reports.

Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification.

P. Bond, D. Ron, H. Harding, 2013, Molecular bioSystems.

Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox

C. Kaminski, D. Ron, E. Avezov, 2013, The Journal of cell biology.

Delivering proteins for export from the cytosol

S. High, I. Sinning, J. Luirink, 2009, Nature Reviews Molecular Cell Biology.

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

Syed Asad Rahman, Annette S. Little, S. Lawo, 2017, Scientific Reports.

A Flexible, Pooled CRISPR Library for Drug Development Screens

S. Lawo, C. le Sage, D. Sorrell, 2020, The CRISPR journal.

Dissecting the physiological role of selective transmembrane-segment retention at the ER translocon

S. High, B. Cross, 2009, Journal of Cell Science.

Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors

A. Mosley, A. Shekhar, C. le Sage, 2021, Science Translational Medicine.

Specific transmembrane segments are selectively delayed at the ER translocon during opsin biogenesis.

S. High, B. Cross, N. Ismail, 2008, The Biochemical journal.

Positional editing of transmembrane domains during ion channel assembly

G. von Heijne, J. Warwicker, S. High, 2013, Journal of Cell Science.

Multimodal Screening—The Future of Drug Discovery and Development

Benedict C. S. Cross, B. Cross, 2020 .

Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein

S. High, E. Wiertz, Aleksandr Mironov, 2009, Molecular membrane biology.