T. Renno

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Primary Form of the Signaling Receptor Cleaved/Associated TLR3 Represents the

J. Casanova, Shen-Ying Zhang, Michael J. Ciancanelli, 2013 .

Cleaved/Associated TLR3 Represents the Primary Form of the Signaling Receptor

J. Casanova, Shen-Ying Zhang, S. Lebecque, 2013, The Journal of Immunology.

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8

S. Lebecque, G. Jacquemin, T. Renno, 2012, Cell Death and Differentiation.

in Human Cancer Cells TLR3 Can Directly Trigger Apoptosis

S. Lebecque, T. Renno, B. Salaun, 2010 .

TLR3 Is a Death Receptor Target in Cancer Therapy

S. Lebecque, T. Renno, Y. Estornes, 2017 .

ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2

E. Gilson, G. Pagès, T. Renno, 2016, Oncotarget.

Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo

M. Hahne, H. Macdonald, T. Renno, 1995, The Journal of experimental medicine.

Expression of B220 on activated T cell blasts precedes apoptosis.

J. Tschopp, M. Hahne, H. Macdonald, 1997, European journal of immunology.

LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation

I. Mikaélian, T. Renno, V. Petrilli, 2012, Cell Death and Disease.

Cutting edge: apoptosis of superantigen-activated T cells occurs preferentially after a discrete number of cell divisions in vivo.

H. Macdonald, T. Renno, A. Attinger, 1999, Journal of immunology.

The hexosamine pathway and coat complex II promote malignant adaptation to nutrient scarcity

Y. Couté, S. Lebecque, J. Guitton, 2022, Life Science Alliance.

Dual function of MyD88 in inflammation and oncogenesis: implications for therapeutic intervention

T. Renno, F. Virard, I. Coste, 2014, Current opinion in oncology.

Unavailability of CD147 leads to selective erythrocyte trapping in the spleen.

H. Macdonald, J. Bonnefoy, T. Renno, 2001, Blood.

Precancerous lesions upon sporadic activation of β-catenin in mice

T. Brabletz, J. Freund, T. Renno, 2007 .

Inflammatory cytokines in the brain: does the CNS shape immune responses?

T. Owens, T. Renno, M. Krakowski, 1994, Immunology today.

Mycobacterium tuberculosis Intracellular Reduces the Viability of Fas Ligand-Induced Apoptosis of Infected Human

P. Meylan, M. Oddo, T. Renno, 2017 .

Superantigens in Autoimmune Diseases: Still More Shades of Gray

H. Acha‐Orbea, T. Renno, H. Acha-Orbea, 1996, Immunological reviews.

Viral Superantigen-Induced Negative Selection of TCR Transgenic CD4 + CD8 + Thymocytes Depends on Activation, but not Proliferation

H. Macdonald, Í. Azcoitia, F. Anjuère, 1998 .

in Human Cancer Cells TLR3 Can Directly Trigger Apoptosis

S. Lebecque, T. Renno, B. Salaun, 2010 .

Impaired fetal thymocyte development after efficient adenovirus-mediated inhibition of NF-kappa B activation.

C. Jongeneel, T. Renno, T. Bakker, 1999, Journal of immunology.

Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand

J. Tschopp, M. Hahne, H. Macdonald, 1996, The Journal of experimental medicine.

Disruption of the langerin/CD207 Gene Abolishes Birbeck Granules without a Marked Loss of Langerhans Cell Function

B. Malissen, S. Lebecque, A. Kissenpfennig, 2005, Molecular and Cellular Biology.

The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated

S. Ansieau, T. Renno, N. Aznar, 2022, Cancers.

Soluble CD86 is a costimulatory molecule for human T lymphocytes.

J. Bonnefoy, G. Caron, T. Renno, 2000, Immunity.

Macrophages(OmpA) Binds to and Activates Human Cutting Edge: Outer Membrane Protein A

T. Baussant, J. Bonnefoy, G. Caron, 2000 .

A Role for CD147 in Thymic Development

H. Macdonald, J. Bonnefoy, T. Renno, 2002, The Journal of Immunology.

Cisplatin unleashes Toll-like receptor 3-mediated apoptosis through the downregulation of c-FLIP in malignant mesothelioma.

S. Lantuejoul, S. Lebecque, C. Blanquart, 2019, Cancer letters.

Primary Form of the Signaling Receptor Cleaved/Associated TLR3 Represents the

J. Casanova, Shen-Ying Zhang, Michael J. Ciancanelli, 2013 .

Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis.

T. Owens, T. Renno, R. Zeine, 1994, International immunology.

A Gender-Dependent Molecular Switch of Inflammation via MyD88/Estrogen Receptor-Alpha Interaction

I. Treilleux, S. Lebecque, B. Badran, 2018, bioRxiv.

Cell Divisions In Vivo Preferentially After a Discrete Number of Superantigen-Activated T Cells Occurs Cutting Edge : Apoptosis of

H. Macdonald, Bakker, T. Renno, 1999 .

Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice

J. Antel, C. Piccirillo, T. Owens, 1994, Journal of Neuroimmunology.

Brief report Dual function of MyD 88 in RAS signaling and inflammation , leading to mouse and human cell transformation

P. Hainaut, A. Eychène, S. Lebecque, 2018 .

ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress

A. Barthelaix, Cédric Duret, T. Renno, 2020, Cancers.

A highly sensitive in vitro infection assay to explore early stages of mouse mammary tumor virus infection

T. Renno, S. Vacheron, H. Acha-Orbea, 1997, Journal of virology.

Precancerous lesions upon sporadic activation of beta-catenin in mice.

T. Brabletz, J. Freund, T. Renno, 2007, Gastroenterology.

The involvement of an ATP-gated ion channel, P(2X1), in thymocyte apoptosis.

J. Bonnefoy, S. Valera, G. Buell, 1996, Immunity.

NFAT-1, Sp-1, Sp-3, and miR-21: New regulators of chemokine C receptor 7 expression in mature human dendritic cells.

A. Burny, M. Fayyad-kazan, B. Badran, 2015, Human immunology.

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor‐α in the central nervous system

Moses Rodriguez, T. Owens, A. Peterson, 1997, European journal of immunology.

Activated B cells express functional Fas ligand

J. Tschopp, L. French, M. Hahne, 1996, European journal of immunology.

What's new in the field of cancer vaccines?

A. Vicari, T. Renno, S. Saeland, 2003, Cellular and Molecular Life Sciences CMLS.

Characterization of the non-functional Fas ligand of gld mice.

M C Peitsch, M. Peitsch, J. Tschopp, 1995, International immunology.

Targeting the cell and non-cell autonomous regulation of 47S synthesis by GCN2 in colon cancer

G. Ichim, Laura Cussonneau, J. Guitton, 2023, bioRxiv.

Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway

S. Lebecque, A. Barthelaix, T. Renno, 2016, Scientific Reports.

OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway

P. Romero, I. Miconnet, T. Baussant, 2000, Nature Immunology.

Cutting Edge: Outer Membrane Protein A (OmpA) Binds to and Activates Human Macrophages

T. Baussant, J. Bonnefoy, G. Caron, 2000, The Journal of Immunology.

TLR3 Can Directly Trigger Apoptosis in Human Cancer Cells1

S. Lebecque, T. Renno, B. Salaun, 2006, The Journal of Immunology.

KfouryToll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis.

A. Viari, V. Hervieu, P. Saintigny, 2019, Journal of hepatology.

Dual Role of TLR3 in Inflammation and Cancer Cell Apoptosis

S. Lebecque, T. Renno, Y. Estornes, 2013 .

Dual Role of TLR 3 in Inflammation and Cancer Cell Apoptosis

S. Lebecque, T. Renno, Y. Estornes, 2013 .

p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose.

F. Fauvet, L. Payen, T. Renno, 2013, Molecular cell.

Efficient adenoviral transfer of NF‐κB inhibitor sensitizes melanoma to tumor necrosis factor‐mediated apoptosis

C. Jongeneel, T. Renno, T. Bakker, 1999, International journal of cancer.

Cancer Vaccine Design: A Novel Bacterial Adjuvant for Peptide-Specific CTL Induction

P. Romero, I. Miconnet, J. Bonnefoy, 2001, The Journal of Immunology.

Release of c-FLIP brake selectively sensitizes human cancer cells to TLR3-mediated apoptosis

N. Le Stang, S. Lantuejoul, S. Lebecque, 2018, Cell Death & Disease.

A Pilot Study to Develop Paraneoplastic Cerebellar Degeneration Mouse Model.

R. Liblau, L. Yshii, T. Renno, 2023, Cerebellum.

Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation.

P. Hainaut, A. Eychène, S. Lebecque, 2010, The Journal of clinical investigation.

Expression of B220 on activated T cell blasts precedes apoptosis

J. Tschopp, M. Hahne, H. Macdonald, 1998 .

AB668, a novel highly selective protein kinase CK2 inhibitor with a distinct anti-tumor mechanism as compared to CX-4945 and SGC-CK2-1

J. Delcros, J. Guichou, I. Krimm, 2022, bioRxiv.

Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis.

H. Macdonald, P. Meylan, M. Oddo, 1998, Journal of immunology.

Oral cavity squamous cell carcinomas in patients with no identified risk factors: Feeling like an outsider.

B. Fervers, T. Renno, F. Virard, 2022, European journal of cancer care.

Interferon-γ in Progression to Chronic Demyelination and Neurological Deficit Following Acute EAE

R. Simone, Moses Rodriguez, T. Owens, 1998, Molecular and Cellular Neuroscience.

TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines.

C. Piccirillo, T. Owens, T. Renno, 1995, Journal of immunology.

Release of c-FLIP brake selectively sensitizes human cancer cells to TLR3-mediated apoptosis

N. Le Stang, S. Lantuejoul, S. Lebecque, 2018, Cell Death & Disease.

Characterisation of an experimental mouse model of exposure to nanoparticles. Relevance to human sarcoidosis

J. Bernaudin, S. Lebecque, A. Calender, 2015 .

Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand

M. Hahne, H. Macdonald, T. Renno, 1996, The Journal of experimental medicine.

2D cell culture on soft hydrogel drives an endoplasmic reticulum stress-dependent S quiescence underlying molecular traits of pulmonary basal cells

S. Ansieau, Cédric Duret, T. Renno, 2023, bioRxiv.

Pemetrexed Hinders Translation Inhibition upon Low Glucose in Non-Small Cell Lung Cancer Cells

Laura Cussonneau, Cédric Duret, T. Renno, 2021, Metabolites.

MyD88 in DNA repair and cancer cell resistance to genotoxic drugs.

S. Lebecque, B. Badran, N. Hussein, 2013, Journal of the National Cancer Institute.

Viral superantigen-induced negative selection of TCR transgenic CD4+ CD8+ thymocytes depends on activation, but not proliferation.

H. Macdonald, Í. Azcoitia, T. Renno, 1998, Blood.

Soft extracellular matrix drives endoplasmic reticulum stress-dependent S quiescence underlying molecular traits of pulmonary basal cells.

T. Renno, M. Ilie, Joelle Fauvre, 2024, Acta biomaterialia.