A. Shiau

Chih-Hsin Hsu, A. Shiau, Chao-Liang Wu, 2020, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Amelioration of experimental arthritis by a telomerase-dependent conditionally replicating adenovirus that targets synovial fibroblasts.

A. Shiau, Chao-Liang Wu, Chrong-Reen Wang, 2009, Arthritis and rheumatism.

Gene therapy for bladder cancer using E1B-55 kD-deleted adenovirus in combination with adenoviral vector encoding plasminogen kringles 1–5

M. Lai, C. Lee, A. Shiau, 2003, British Journal of Cancer.

Zhankuic acid A as a novel JAK2 inhibitor for the treatment of concanavalin A-induced hepatitis.

L. Her, A. Shiau, Chao-Liang Wu, 2014, Biochemical pharmacology.

Interleukin-23 Mediates Osteoclastogenesis in Collagen-Induced Arthritis by Modulating MicroRNA-223

A. Shiau, J. Hsieh, Po-Ting Wu, 2022, International journal of molecular sciences.

Amelioration of rat collagen-induced arthritis through CD4+ T cells apoptosis and synovial interleukin-17 reduction by indoleamine 2,3-dioxygenase gene therapy.

M. Lai, Chi-Chen Lin, I. Jou, 2011, Human gene therapy.

Nitric Oxide Nonstructural Protein 1 Via Production of Antibodies Against Dengue Virus Endothelial Cell Apoptosis Induced by

Yee‐Shin Lin, H-S Liu, H. Lei, 2002 .

Heterologous protection in pigs induced by a plasmid-cured and crp gene-deleted Salmonella choleraesuis live vaccine.

C. Chu, A. Shiau, Chao-Liang Wu, 2007, Vaccine.

Upregulation of Fibrinogen-Like 1 Expression Contributes to Reducing the Progression of Preeclampsia

Chung-Hwan Chen, A. Shiau, Chao-Liang Wu, 2021, Frontiers in Cell and Developmental Biology.

Endothelial Cell Apoptosis Induced by Antibodies Against Dengue Virus Nonstructural Protein 1 Via Production of Nitric Oxide

Yee‐Shin Lin, H-S Liu, H. Lei, 2002, The Journal of Immunology.

Amelioration of collagen-induced arthritis in rats by adenovirus-mediated PTEN gene transfer.

I. Jou, M. Tai, A. Shiau, 2008, Arthritis and rheumatism.

Suppression of collagen-induced arthritis by intra-articular lentiviral vector-mediated delivery of Toll-like receptor 7 short hairpin RNA gene

C. Lee, A. Shiau, Y-S Lin, 2011, Gene Therapy.

Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities

M. Lai, A. Shiau, Chao-Liang Wu, 2009, FEBS letters.

Implantable Microneedles with an Immune-Boosting Function for Effective Intradermal Influenza Vaccination.

Mei-Chin Chen, A. Shiau, Yu-Hung Chen, 2019, Acta biomaterialia.

Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis.

I. Jou, D. Shieh, Ching-Shan Tsai, 2005, Arthritis and rheumatism.

Retrovirus-mediated transfer of prothymosin gene inhibits tumor growth and prolongs survival in murine bladder cancer

M-Y Chang, A. Shiau, Pey-Ru Lin, 2001, Gene Therapy.

Enhancement of humoral and cellular immune responses by an oral Salmonella choleraesuis vaccine expressing porcine prothymosin alpha.

C. Chu, A. Shiau, Chao-Liang Wu, 2005, Vaccine.

Anti-Inflammatory Properties TLR4/MD-2 Antagonist with Is a Novel Selective camphoratus Taiwanofungus Zhankuic Acid Isolated from

Jai-Sing Yang, A. Shiau, Yu-Fon Chen, 2014 .

Inhibition of cartilage damage by pro-opiomelanocortin prohormone overexpression in a rat model of osteoarthritis

I. Jou, Guei-Sheung Liu, M. Tai, 2011, Experimental biology and medicine.

Interruption of the long non-coding RNA HOTAIR signaling axis ameliorates chemotherapy-induced cachexia in bladder cancer

Feng-Chih Kuo, Y. Tsai, A. Shiau, 2022, Journal of Biomedical Science.

Characterization in Effective Stimulation on the Magnitude, Gating, Frequency Dependence, and Hysteresis of INa Exerted by Picaridin (or Icaridin), a Known Insect Repellent

Sheng-Nan Wu, A. Shiau, Hsin-Yen Cho, 2022, International journal of molecular sciences.

This information is current as Dengue Virus Nonstructural Protein 1 Activation Induced by Antibodies against Adhesion Molecules during Endothelial Cell Expression of Cytokine , Chemokine , and

Yee‐Shin Lin, H-S Liu, H. Lei, 2004 .

One-dimensional poly(L-lysine)-block-poly(L-threonine) assemblies exhibit potent anticancer activity by enhancing membranolysis.

A. Shiau, Chao-Liang Wu, Jeng-Shiung Jan, 2017, Acta biomaterialia.

The Inhibitory Effect of Staphylococcus epidermidis Slime on the Phagocytosis of Murine Peritoneal Macrophages Is Interferon‐Independent

A. Shiau, Chao-Liang Wu, 1998, Microbiology and immunology.

Efficient Reactivation of Latent Herpes Simplex Virus from Mouse Central Nervous System Tissues

K. Hsu, H. Lei, Shun-Hua Chen, 2006, Journal of Virology.

Hepatitis C virus core protein fused to hepatitis B virus core antigen for serological diagnosis of both hepatitis C and hepatitis B infections by ELISA

Ting Chang, A. Shiau, Chao-Liang Wu, 1999, Journal of medical virology.

In vivo expression of thrombospondin-1 suppresses the formation of peritoneal adhesion in rats

I. Jou, A. Shiau, Yun-Chih Jung, 2019, World journal of gastrointestinal surgery.

Immunological aspects of hepatitis B virus core antigen and its derivatives

A. Shiau, 1993 .

Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene

A. Shiau, C. Wu, H. Yang, 1998, Gene Therapy.

Enhancement of antitumor immune response by targeted interleukin-12 electrogene transfer through antiHER2 single-chain antibody in a murine bladder tumor model.

T. Tzai, Y. Tsai, A. Shiau, 2009, Vaccine.

A simple selection system for construction of recombinant gD-negative pseudorabies virus as a vaccine vector.

A. Shiau, Chao-Liang Wu, Chiau-Yuang Tsai, 2002, Vaccine.

Vaccination with the glycoprotein D gene of pseudorabies virus delivered by nonpathogenic Escherichia coli elicits protective immune responses.

C. Chu, A. Shiau, W. Su, 2001, Vaccine.

Prothymosin α promotes cell proliferation in NIH3T3 cells

A. Shiau, Chao-Liang Wu, C. Lin, 1997 .

Novel Autoregulatory Function of Hepatitis B Virus M Protein on Surface Gene Expression*

M. Lai, H-S Liu, Cheng‐Chan Lu, 2005, Journal of Biological Chemistry.

Prothymosin α overexpression contributes to the development of pulmonary emphysema

A. Shiau, Y. Tseng, Chao-Liang Wu, 2013, Nature Communications.

Tumor-Selective Replication of an Oncolytic Adenovirus Carrying Oct-3/4 Response Elements in Murine Metastatic Bladder Cancer Models

A. Shiau, Chao-Liang Wu, Yi-Te Yo, 2008, Clinical Cancer Research.

Mitochondrial ribosomal protein S36 delays cell cycle progression in association with p53 modification and p21WAF1/CIP1 expression

A. Shiau, Chao-Liang Wu, Yi-Te Yo, 2007, Journal of cellular biochemistry.

Novel Strategy for Generation and Titration of Recombinant Adeno-Associated Virus Vectors

A. Shiau, Chao-Liang Wu, Pu-Ste Liu, 2005, Journal of Virology.

Hepatitis B Virus X Protein Sensitizes Hepatocellular Carcinoma Cells to Cytolysis Induced by E 1 B-deleted Adenovirus through the Disruption of p 53 Function 1

A. Shiau, J. Hsieh, Chao-Liang Wu, 2003 .

Prothymosin alpha enhances protective immune responses induced by oral DNA vaccination against pseudorabies delivered by Salmonella choleraesuis.

A. Shiau, C. Liao, Y. Chen, 2001, Vaccine.

MicroRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells.

Wen-Tsung Huang, Jan-Gowth Chang, Pei-Jung Lu, 2012, International journal of molecular medicine.

Brief report: amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223.

Chi-Chen Lin, I. Jou, A. Shiau, 2012, Arthritis and rheumatism.

Endothelial Cell Apoptosis Induced by Antibodies Against Dengue Virus Nonstructural Protein 1 Via Production of Nitric Oxide1

Yee‐Shin Lin, H-S Liu, H. Lei, 2002, The Journal of Immunology.

Systemic administration of attenuated Salmonella choleraesuis carrying thrombospondin-1 gene leads to tumor-specific transgene expression, delayed tumor growth and prolonged survival in the murine melanoma model

A. Shiau, Chao-Liang Wu, Che-Hsin Lee, 2005, Cancer Gene Therapy.

Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy

A. Shiau, J. Hsieh, C. Chou, 2008, Cancer Gene Therapy.

Low-dose etoposide enhances telomerase-dependent adenovirus-mediated cytosine deaminase gene therapy through augmentation of adenoviral infection and transgene expression in a syngeneic bladder tumor model.

T. Tzai, A. Shiau, Chao-Liang Wu, 2006, Cancer research.

Transgene Expression in a Syngeneic Bladder Tumor Model through Augmentation of Adenoviral Infection and Adenovirus-Mediated Cytosine Deaminase Gene Therapy Low-Dose Etoposide Enhances Telomerase-Dependent

T. Tzai, A. Shiau, Chao-Liang Wu, 2006 .

Elovl6 is a negative clinical predictor for liver cancer and knockdown of Elovl6 reduces murine liver cancer progression

A. Shiau, Chao-Liang Wu, Pensée Wu, 2018, Scientific Reports.

Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells

Jan-Gowth Chang, P. Lu, K. Yeh, 2010, Cancer science.

Enhancement of antitumor activity of gammaretrovirus carrying IL-12 gene through genetic modification of envelope targeting HER2 receptor: a promising strategy for bladder cancer therapy

T. Tzai, Y. Tsai, A. Shiau, 2010, Cancer Gene Therapy.

Galectin-1-Mediated Tumor Invasion and Metastasis, Up-Regulated Matrix Metalloproteinase Expression, and Reorganized Actin Cytoskeletons

Hsiao-Chin Hong, T. Hong, D. Shieh, 2009, Molecular Cancer Research.

Prothymosin‐α enhances phosphatase and tensin homolog expression and binds with tripartite motif‐containing protein 21 to regulate Kelch‐like ECH‐associated protein 1/nuclear factor erythroid 2‐related factor 2 signaling in human bladder cancer

T. Tzai, Y. Tsai, A. Shiau, 2019, Cancer science.

Upregulation of galectin-3 in influenza A virus infection promotes viral RNA synthesis through its association with viral PA protein

A. Shiau, Chao-Liang Wu, Hao-Earn Chong, 2023, Journal of Biomedical Science.

Galectin-1 Binds to Influenza Virus and Ameliorates Influenza Virus Pathogenesis

Jen-Ren Wang, Ching-Ho Wang, C. Chu, 2011, Journal of Virology.

Antisense oligonucleotide specific for transforming growth factor-beta 1 inhibit both in vitro and in vivo growth of MBT-2 murine bladder cancer.

T. Tzai, A. Shiau, C. Lin, 1998, Anticancer research.

Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer

Wen‐Horng Yang, A. Shiau, W. Su, 2016, Oncotarget.

Acquisition of an enhanced aggressive phenotype in human lung cancer cells selected by suboptimal doses of cisplatin following cell deattachment and reattachment.

A. Shiau, J. Hsieh, Chao-Liang Wu, 2012, Cancer letters.

Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140‐3p and 140‐5p

A. Shiau, Chao-Liang Wu, Chrong-Reen Wang, 2016, Arthritis & rheumatology.

Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis

A. Shiau, J. Hsiao, S. Tsai, 2003, British Journal of Cancer.

Elovl6 is a poor prognostic predictor in breast cancer.

A. Shiau, C. Tsao, Chao-Liang Wu, 2016, Oncology letters.

The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients

A. Shiau, Y. Tseng, Chao-Liang Wu, 2021, Cells.

TGF-β1 conjugated to gold nanoparticles results in protein conformational changes and attenuates the biological function.

T. Tzai, Y. Tsai, A. Shiau, 2013, Small.

Influenza a virus NS1 resembles a TRAF3-interacting motif to target the RNA sensing-TRAF3-type I IFN axis and impair antiviral innate immunity

Jen-Ren Wang, Sheng-Wen Huang, Kuan-Ru Chen, 2021, Journal of biomedical science.

TBK1-associated Protein in Endolysosomes (TAPE) Is an Innate Immune Regulator Modulating the TLR3 and TLR4 Signaling Pathways*

J. Qin, H. Lei, Lihua Lai, 2010, The Journal of Biological Chemistry.

A biological strategy for fabrication of Au/EGFP nanoparticle conjugates retaining bioactivity

Dar-Bin Shieh, Chen-Sheng Yeh, Chao-Liang Wu, 2004 .

Methotrexate conjugated to gold nanoparticles inhibits tumor growth in a syngeneic lung tumor model.

Chao-Liang Wu, Dong-Hwang Chen, A. Shiau, 2007, Molecular pharmaceutics.

Potent antitumor activity of Oct4 and hypoxia dual-regulated oncolytic adenovirus against bladder cancer

M-Y Chang, C. Lee, A. Shiau, 2015, Gene Therapy.

Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection.

L. Chao, J. Chao, I. Jou, 2008, Human gene therapy.

Therapeutic HER2/Neu DNA vaccine inhibits mouse tumor naturally overexpressing endogenous neu.

M. Lai, Chi-Chen Lin, M. Tao, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

Antibodies from dengue patient sera cross‐react with endothelial cells and induce damage

Yee‐Shin Lin, H-S Liu, H. Lei, 2003, Journal of medical virology.

Prognostic relevance of prothymosin-alpha expression in human upper urinary tract transitional cell carcinoma.

T. Tzai, Y. Tsai, C. Tung, 2009, Urology.

B cells are required for tumor-targeting Salmonella in host

A. Shiau, J. Hsieh, Chao-Liang Wu, 2011, Applied Microbiology and Biotechnology.

Intraarticular overexpression of Smad7 ameliorates experimental arthritis

A. Shiau, Chao-Liang Wu, Chrong-Reen Wang, 2016, Scientific Reports.

Over‐expression of prothymosin‐α antagonizes TGFβ signalling to promote the development of emphysema

A. Shiau, Y. Tseng, Chao-Liang Wu, 2016, The Journal of pathology.

Amelioration of collagen-induced arthritis in rats by adenovirus-mediated PTEN gene transfer

M. Tai, A. Shiau, Chao-Liang Wu, 2007 .

Aberrant prothymosin-alpha expression in human bladder cancer.

T. Tzai, Y. Tsai, A. Shiau, 2009, Urology.

Increased apoptotic potential and dose‐enhancing effect of gold nanoparticles in combination with single‐dose clinical electron beams on tumor‐bearing mice

A. Shiau, Chao-Liang Wu, Chih-Jui Chang, 2008, Cancer science.

Targeting Intra-Pulmonary P53-Dependent Long Non-Coding RNA Expression as a Therapeutic Intervention for Systemic Lupus Erythematosus-Associated Diffuse Alveolar Hemorrhage

Y. Chou, A. Shiau, Chao-Liang Wu, 2021, International journal of molecular sciences.

P53-derived hybrid peptides induce apoptosis of synovial fibroblasts in the rheumatoid joint

A. Shiau, Chao-Liang Wu, Chrong-Reen Wang, 2017, Oncotarget.

Focused ion beam-fabricated Au micro/nanostructures used as a surface enhanced Raman scattering-active substrate for trace detection of molecules and influenza virus

J. Liao, Chia-Wei Chang, A. Shiau, 2011, Nanotechnology.

Prothymosin alpha interacts with C-terminal domain of histone H1 and dissociates p53-histone H1 complex

A. Evstafieva, A. Shiau, Chao-Liang Wu, 2011, Molecular Biology.

Oral DNA vaccine adjuvanted with cyclic peptide nanotubes induced a virus-specific antibody response in ducklings against goose parvovirus

J. Liaw, C. Chu, A. Shiau, 2023, The veterinary quarterly.

Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes.

A. Shiau, H. Ou, Chao-Liang Wu, 2020, Clinical science.

Prothymosin-α Overexpression Contributes to the Development of Insulin Resistance.

A. Shiau, H. Ou, Chao-Liang Wu, 2015, The Journal of clinical endocrinology and metabolism.

CD8+ T Cell-Induced Expression of Tissue Inhibitor of Metalloproteinses-1 Exacerbated Osteoarthritis

I. Jou, Bih-O Lee, Shun-Hua Chen, 2013, International journal of molecular sciences.

Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage

A. Shiau, Chao-Liang Wu, Chrong-Reen Wang, 2023, International journal of molecular sciences.

Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer

Chien-Feng Li, A. Shiau, Chao-Liang Wu, 2019, BMC Cancer.

Amelioration of experimental arthritis by intra-articular injection of an epidermal growth factor receptor tyrosine kinase inhibitor.

A. Shiau, C. Wu, S. Chen, 2015, Clinical and Experimental Rheumatology.

Mutated epitopes of hepatitis B surface antigen fused to the core antigen of the virus induce antibodies that react with the native surface antigen

A. Shiau, K. Murray, 1997, Journal of medical virology.

FRI0053 Amelioration of Experimental Arthritis by Dissociating The Binding of P53 Family Members with Inhibitory Apoptosis Stimulating Protein of P53 To Induce Apoptosis in Synovial Fibroblast

I. Jou, A. Shiau, C-R Wang, 2016 .

Immunization with TGF-beta antisense oligonucleotide-modified autologous tumor vaccine enhances the antitumor immunity of MBT-2 tumor-bearing mice through upregulation of MHC class I and Fas expressions.

Li Liu, T. Tzai, A. Shiau, 2000, Anticancer research.

Multivalent dipeptidyl peptidase IV fragment-nanogold complex inhibits cancer metastasis by blocking pericellular fibronectin.

Yu Lin, A. Shiau, Chao-Liang Wu, 2023, Biomaterials advances.

Up-Regulated Expression of Pro-Apoptotic Long Noncoding RNA lincRNA-p21 with Enhanced Cell Apoptosis in Lupus Nephritis

Y. Chou, A. Shiau, Chao-Liang Wu, 2020, International journal of molecular sciences.

Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer

Chien-Feng Li, A. Shiau, Chao-Liang Wu, 2019, BMC Cancer.

Expression of prothymosin α in lung cancer is associated with squamous cell carcinoma and smoking.

Chien-Feng Li, A. Shiau, C. Tsao, 2019, Oncology letters.

Amelioration of Murine Colitis by Attenuated Salmonella choleraesuis Encoding Interleukin-19

A. Shiau, Chao-Liang Wu, Che-Hsin Lee, 2023, Microorganisms.

Scutellaria barbata inhibits angiogenesis through downregulation of HIF‐1 α in lung tumor

A. Shiau, J. Hsieh, Chao-Liang Wu, 2014, Environmental toxicology.

Amelioration of rat collagen-induced arthritis through CD4+ T cells apoptosis and synovial interleukin-17 reduction by indoleamine 2,3-dioxygenase gene therapy.

M. Lai, Chi-Chen Lin, I. Jou, 2011, Human gene therapy.

Toll-like Receptor 4 Mediates an Antitumor Host Response Induced by Salmonella choleraesuis

A. Shiau, Chao-Liang Wu, Che-Hsin Lee, 2008, Clinical Cancer Research.

Oct4 and Hypoxia Dual-Regulated Oncolytic Adenovirus Armed with shRNA-Targeting Dendritic Cell Immunoreceptor Exerts Potent Antitumor Activity against Bladder Cancer

A. Shiau, Chao-Liang Wu, G. Shieh, 2023, Biomedicines.

The effect of thymosin on experimental herpes simplex virus infections.

A. Shiau, C. L. Wu, K. Y. Huang, 1988, Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association.

Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection.

L. Chao, J. Chao, I. Jou, 2008, Human gene therapy.

Intra-articular lentivirus-mediated delivery of galectin-3 shRNA and galectin-1 gene ameliorates collagen-induced arthritis

C. Lee, A. Shiau, Yi-Te Yo, 2010, Gene Therapy.

Transcription Factor Snail Regulates Tumor Necrosis Factor α–Mediated Synovial Fibroblast Activation in the Rheumatoid Joint

Chi-Chen Lin, I. Jou, A. Shiau, 2015, Arthritis & rheumatology.

Molnupiravir, a ribonucleoside antiviral prodrug against SARS-CoV-2, alters the voltage-gated sodium current and causes adverse events.

Sheng-Nan Wu, A. Shiau, Chao-Liang Wu, 2023, Virology.

Syngeneic mesenchymal stem cells loaded with telomerase-dependent oncolytic adenoviruses enhance anti-metastatic efficacy

A. Shiau, G. Shieh, B. Su, 2024, Stem cells translational medicine.

Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities

M. Lai, A. Shiau, Chao-Liang Wu, 2009, FEBS letters.