A. Miyazaki

发表

Icing after eccentric contraction-induced muscle damage perturbs the disappearance of necrotic muscle fibers and phenotypic dynamics of macrophages in mice.

Katsuhiko Suzuki, T. Sonomura, Takamitsu Arakawa, 2021, Journal of applied physiology.

Synthesis and preliminary characterization of radioiodinated benzofuran-3-yl-(indol-3-yl)maleimide derivatives as potential SPECT imaging probes for the detection of glycogen synthase kinase-3β (GSK-3β) in the brain.

H. Saji, H. Kimura, M. Ono, 2016, Journal of labelled compounds & radiopharmaceuticals.

Transformation of mu-opioid receptor agonists into biologically potent mu-opioid receptor antagonists.

Qiang Li, Y. Tsuda, Y. Okada, 2007, Bioorganic & medicinal chemistry.

Design and synthesis of opioidmimetics containing 2',6'-dimethyl-L-tyrosine and a pyrazinone-ring platform.

Y. Tsuda, Y. Okada, A. Miyazaki, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of 3,6-bis[H-Tyr/H-Dmt-NH(CH2)m,n]-2(1H)pyrazinone derivatives: function of alkyl chain length on opioid activity.

Y. Tsuda, Y. Okada, A. Miyazaki, 2006, Bioorganic & medicinal chemistry letters.

Studies on the structure-activity relationship of 2',6'-dimethyl-l-tyrosine (Dmt) derivatives: bioactivity profile of H-Dmt-NH-CH(3).

Y. Fujita, Y. Tsuda, Y. Okada, 2005, Bioorganic & medicinal chemistry letters.

Icing after skeletal muscle injury decreases M1 macrophage accumulation and TNF-α expression during the early phase of muscle regeneration in rats

T. Sonomura, Takamitsu Arakawa, Masato Kawashima, 2022, Histochemistry and Cell Biology.

Potent in vivo antinociception and opioid receptor preference of the novel analogue [Dmt1]endomorphin-1

Y. Fujita, Y. Tsuda, Y. Okada, 2006, Pharmacology Biochemistry and Behavior.

New cyclic somatostatin analogues containing a pyrazinone ring: importance of Tyr for antiproliferative activity.

G. Kéri, S. Fukushima, Y. Tsuda, 2008, Bioorganic & medicinal chemistry letters.

A solvent-dependent chirality-switchable thia-Michael addition to α,β-unsaturated carboxylic acids using a chiral multifunctional thiourea catalyst† †Electronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, copies of 1H and 13C NMR spectra, and HPLC chromato

T. Kimachi, Yusuke Kobayashi, A. Miyazaki, 2020, Chemical science.

Studies on the mechanism of 1,2-dihydropyrazin-2-one ring formation from dipeptidyl chloromethyl ketone and its chemical properties: immediate deamination during catalytic hydrogenation.

Y. Fujita, Y. Tsuda, Y. Okada, 2005, Chemical & pharmaceutical bulletin.

Immediate deamination from the aminomethyl group attached to 1,2-dihydropyrazin-2-one derivative during catalytic hydrogenation

Y. Fujita, Y. Tsuda, Y. Okada, 2002 .

Differentiation of opioid receptor preference by [Dmt1]endomorphin-2-mediated antinociception in the mouse.

Y. Fujita, Y. Tsuda, Y. Okada, 2005, European journal of pharmacology.

Inhibitory effect of somatostatin Peptide analogues on DNA polymerase activity and human cancer cell proliferation.

F. Sugawara, H. Yoshida, Y. Mizushina, 2010, Anticancer research.

18F-Labeled Pyrido[3,4-d]pyrimidine as an Effective Probe for Imaging of L858R Mutant Epidermal Growth Factor Receptor.

H. Saji, R. Nishii, I. Kawasaki, 2017, ACS medicinal chemistry letters.

18 F ‑ Labeled Pyrido[3,4 ‑ d ]pyrimidine as an E ﬀ ective Probe for Imaging of L858R Mutant Epidermal Growth Factor Receptor

H. Saji, R. Nishii, I. Kawasaki, 2017 .

The Structure-Activity Relationship of Dmt-NH-X

Y. Fujita, Y. Tsuda, Y. Okada, 2004 .

Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β.

H. Yoshida, Y. Mizushina, Y. Tsuda, 2013, Bioorganic & medicinal chemistry.

Design and synthesis of novel type somatostatin analogs with antiproliferative activities on A431 tumor cells

G. Kéri, Y. Tsuda, Y. Okada, 2004 .

New series of potent δ-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif

Y. Fujita, Y. Tsuda, Y. Okada, 2005 .

Systematic Study on the Structure-Activity Relationship of Pyrazinone Ring-Containing Bioactive Opioid Ligands

Y. Tsuda, Y. Okada, A. Miyazaki, 2006 .

Application of liquid chromatography-tandem mass spectrometry for the determination of opioidmimetics in the brain dialysates from rats treated with opioidmimetics intraperitoneally.

S. Fukushima, Y. Tsuda, Y. Okada, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bifunctional [2‘,6‘-Dimethyl-l-tyrosine1]endomorphin-2 Analogues Substituted at Position 3 with Alkylated Phenylalanine Derivatives Yield Potent Mixed μ-Agonist/δ-Antagonist and Dual μ-Agonist/δ-Agonist Opioid Ligands

Y. Tsuda, Y. Okada, A. Miyazaki, 2007 .

Development of potent mu-opioid receptor ligands using unique tyrosine analogues of endomorphin-2.

Y. Fujita, Y. Tsuda, Y. Okada, 2005, Journal of medicinal chemistry.

PET probe detecting non-small cell lung cancer susceptible to epidermal growth factor receptor tyrosine kinase inhibitor therapy.

H. Okazawa, H. Saji, R. Nishii, 2018, Bioorganic & medicinal chemistry.

Synthesis of somatostatin analogues containing C-terminal adamantane and their antiproliferative properties.

G. Kéri, S. Fukushima, Y. Tsuda, 2008, Journal of medicinal chemistry.

Oral bioavailability of a new class of micro-opioid receptor agonists containing 3,6-bis[Dmt-NH(CH(2))(n)]-2(1H)-pyrazinone with central-mediated analgesia.

Y. Fujita, Y. Tsuda, Y. Okada, 2004, Journal of medicinal chemistry.

Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.

Y. Tsuda, Y. Okada, A. Miyazaki, 2007, Journal of Medicinal Chemistry.

Synthesis of somatostatin analogues containing C-terminal adamantane and their antiproliferative properties.

G. Kéri, S. Fukushima, Y. Tsuda, 2008, Journal of medicinal chemistry.