Xiaolei Zhang

发表

Hematogenous Macrophages: A New Therapeutic Target for Spinal Cord Injury

Yuanzhe Ding, Di Zhang, Sheng Wang, 2021, Frontiers in Cell and Developmental Biology.

Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.

Xiaolei Zhang, Xiangyang Wang, Sunli Hu, 2022, Biochemical pharmacology.

The endocrine role of bone: Novel functions of bone-derived cytokines.

Xuan-Qi Zheng, Tao Chen, D. Xing, 2020, Biochemical pharmacology.

The Sirt1/P53 Axis in Diabetic Intervertebral Disc Degeneration Pathogenesis and Therapeutics

Zengjie Zhang, Chenggui Wang, Xiaolei Zhang, 2019, Oxidative medicine and cellular longevity.

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Zengjie Zhang, Xiaolei Zhang, Xiangyang Wang, 2018, Experimental & Molecular Medicine.

Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development

Huazi Xu, Chenggui Wang, Xiaolei Zhang, 2017, Cell Death and Disease.

The therapeutic effect of TBK1 in intervertebral disc degeneration via coordinating selective autophagy and autophagic functions

A. Al Mamun, Xiaolei Zhang, Xiangyang Wang, 2020, Journal of advanced research.

Stabilization of HIF-1α by FG-4592 promotes functional recovery and neural protection in experimental spinal cord injury

Kailiang Zhou, Huazi Xu, Di Zhang, 2016, Brain Research.

Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis

Wei Hu, Xiaolei Zhang, Qi Chen, 2021, Frontiers in Pharmacology.

Echinacoside Upregulates Sirt1 to Suppress Endoplasmic Reticulum Stress and Inhibit Extracellular Matrix Degradation In Vitro and Ameliorates Osteoarthritis In Vivo

Xiaolei Zhang, Junsheng Lou, Yuxin Wang, 2021, Oxidative medicine and cellular longevity.

Xanthohumol suppresses inflammation in chondrocytes and ameliorates osteoarthritis in mice.

Zheng Li, Xiaolei Zhang, Hongyuan Zhang, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Senolytics: Eliminating Senescent Cells and Alleviating Intervertebral Disc Degeneration

Xiaolei Zhang, Yifei Zhou, Yifeng Shi, 2022, Frontiers in Bioengineering and Biotechnology.

Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.

Xiaolei Zhang, Xiangyang Wang, Weiyang Gao, 2020, Food & function.

RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration

Xiaolei Zhang, Xiangyang Wang, Sunli Hu, 2020, Cell proliferation.

Puerarin suppresses inflammation and ECM degradation through Nrf2/HO-1 axis in chondrocytes and alleviates pain symptom in osteoarthritic mice.

Xiaolei Zhang, Chongan Huang, Chaoyong Bei, 2021, Food & function.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

The Potential Role of Cytokines in Diabetic Intervertebral Disc Degeneration

Zengjie Zhang, Xiaolei Zhang, Xiangyang Wang, 2022, Aging and disease.

Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2

Xiaolei Zhang, Xiangyang Wang, Hongyu Chen, 2021, Oxidative medicine and cellular longevity.

Endoplasmic Reticulum Stress and NF-[Formula: see text]B Pathway in Salidroside Mediated Neuroprotection: Potential of Salidroside in Neurodegenerative Diseases.

Huazi Xu, Jianxiang Xu, Chenggui Wang, 2017, The American journal of Chinese medicine.

Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation

Huazi Xu, Sheng Wang, Xiaolei Zhang, 2019, EBioMedicine.

Enhancement of Motor Functional Recovery Using Immunomodulatory Extracellular Vesicles-loaded Injectable Thermosensitive Hydrogel Post Spinal Cord Injury

Hongyuan Xing, Zengjie Zhang, Chenggui Wang, 2022, Chemical Engineering Journal.

New nomograms based on treatment outcome and prognostic factors for patients with spinal diffuse large B-cell lymphoma: A population‐based study

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2020 .

Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP‐9 expression but not direct TJ proteins expression regulation

Huazi Xu, Chenggui Wang, Di Zhang, 2017, Journal of cellular and molecular medicine.

Wogonoside inhibits IL-1β induced catabolism and hypertrophy in mouse chondrocyte and ameliorates murine osteoarthritis

Huazi Xu, Jianxiang Xu, Chenggui Wang, 2017, Oncotarget.

Monascin inhibits IL-1β induced catabolism in mouse chondrocytes and ameliorates murine osteoarthritis.

Huazi Xu, Xiaolei Zhang, Y. Zhan, 2018, Food & function.

Dual regulation of microglia and neurons by Astragaloside IV‐mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury

Xuan-Qi Zheng, Xiaolei Zhang, Xiangyang Wang, 2019, Journal of cellular and molecular medicine.

STING Attenuates ROS Induced intervertebral disc degeneration.

Shanshan Zeng, Xiaolei Zhang, Jinwu Wang, 2021, Osteoarthritis and cartilage.

Exercise-induced FNDC5/irisin protects nucleus pulposus cells against senescence and apoptosis by activating autophagy

Xiaolei Zhang, Lei Yang, Yifeng Shi, 2022, Experimental & Molecular Medicine.

Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway

Xiaolei Zhang, Xiangyang Wang, Yifeng Shi, 2022, Oxidative medicine and cellular longevity.

The effects of lactate and acid on articular chondrocytes function: Implications for polymeric cartilage scaffold design.

Shouan Zhu, Huazi Xu, H. Ouyang, 2016, Acta biomaterialia.

SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis

Xiaolei Zhang, Pei Fan, Xiangyang Wang, 2018, International journal of biological sciences.

BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats

Xiaolei Zhang, Xiangyang Wang, Sunli Hu, 2019, Journal of cellular and molecular medicine.

Sodium lactate promotes stemness of human mesenchymal stem cells through KDM6B mediated glycolytic metabolism.

Shouan Zhu, H. Ouyang, Yishan Chen, 2020, Biochemical and biophysical research communications.

Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration

Zengjie Zhang, Xiaolei Zhang, Xiangyang Wang, 2018, Cell Death & Disease.

4 D-Printed Dynamic Materials in Biomedical Applications: Chemistry, Challenges, and Their Future Perspectives in the Clinical Sector.

P. Makvandi, Xuan-Qi Zheng, Xiaolei Zhang, 2020, Journal of medicinal chemistry.

Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2020, Food & function.

S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2020, Aging.

Salidroside attenuates neuroinflammation and improves functional recovery after spinal cord injury through microglia polarization regulation

Huazi Xu, Jianxiang Xu, Zengjie Zhang, 2017, Journal of cellular and molecular medicine.

Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis.

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2020, Osteoarthritis and cartilage.

Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration

Zengjie Zhang, Yuanzhe Ding, Xiaolei Zhang, 2019, Front. Pharmacol..

Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration

Zengjie Zhang, Xiaolei Zhang, Xiangyang Wang, 2018, Cell Death & Disease.

Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo

Kailiang Zhou, Huazi Xu, Chenggui Wang, 2016, Cell Death and Disease.

TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux.

Huazi Xu, Xiaolei Zhang, Xiangyang Wang, 2019, Osteoarthritis and cartilage.

TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation

Huazi Xu, Zengjie Zhang, Xiaolei Zhang, 2018, Cell Death & Disease.

Urolithin A-induced mitophagy suppresses apoptosis and attenuates intervertebral disc degeneration via the AMPK signaling pathway.

Zengjie Zhang, Xuan-Qi Zheng, Xiaolei Zhang, 2020, Free radical biology & medicine.

20-Deoxyingenol alleviates osteoarthritis by activating TFEB in chondrocytes.

Xiaolei Zhang, Weiyang Gao, Zongyou Pan, 2021, Pharmacological research.

STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway

Xiaolei Zhang, Xiangyang Wang, Jiaoxiang Chen, 2021, Cell death & disease.

The homogeneous and heterogeneous risk factors for occurrence and prognosis in lung cancer patients with bone metastasis

Xiaolei Zhang, Xiangyang Wang, Sunli Hu, 2019, Journal of bone oncology.

Delivery of epidermal growth factor receptor inhibitor via a customized collagen scaffold promotes meniscal defect regeneration in a rabbit model.

Yuehua Wu, H. Ouyang, B. Heng, 2017, Acta biomaterialia.

Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose-induced senescence and apoptosis

Jian Xiao, Xiaolei Zhang, Xiangyang Wang, 2021, Experimental and therapeutic medicine.

CO-Releasing Molecule (CORM)-3 Ameliorates Spinal Cord-Blood Barrier Disruption Following Injury to the Spinal Cord

Huazi Xu, Sheng Wang, Xiaolei Zhang, 2020, Frontiers in Pharmacology.

The Emerging Roles of the Gaseous Signaling Molecules NO, H2S, and CO in the Regulation of Stem Cells.

Xiaolei Zhang, Xiangyang Wang, Gang Zheng, 2020, ACS biomaterials science & engineering.

Lactate down‐regulates matrix systhesis and promotes apoptosis and autophagy in rat nucleus pulposus cells

Xiangyang Wang, Huazi Xu, Huazi Xu, 2014, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: Implications for diabetic intervertebral disc degeneration

Xiangyang Wang, Huazi Xu, Huazi Xu, 2013, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas

C. Yuan, H. Ouyang, Yuzi Xu, 2020, Bone Research.

Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy.

Ruijie Chen, Xiaolei Zhang, Daosen Chen, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Kdm6b regulates cartilage development and homeostasis through anabolic metabolism

Shouan Zhu, H. Ouyang, B. Heng, 2017, Annals of the rheumatic diseases.

Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells.

Xiaolei Zhang, Yifei Zhou, Yaosen Wu, 2022, Journal of cell science.

Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells

Xiaolei Zhang, Xiangyang Wang, Yan Lin, 2022, Frontiers in Cell and Developmental Biology.

Melatonin protects vertebral endplate chondrocytes against apoptosis and calcification via the Sirt1‐autophagy pathway

Zengjie Zhang, Chenggui Wang, Xiaolei Zhang, 2018, Journal of cellular and molecular medicine.

Therapeutic Potential of Naringin for Intervertebral Disc Degeneration: Involvement of Autophagy Against Oxidative Stress-Induced Apoptosis in Nucleus Pulposus Cells.

Zengjie Zhang, Chenggui Wang, Xiaolei Zhang, 2018, The American journal of Chinese medicine.

HECTD1‐Mediated Ubiquitination and Degradation of Rubicon Regulates Autophagy and Osteoarthritis Pathogenesis

Yuzi Xu, Haotian Shen, H. Ouyang, 2022, Arthritis & rheumatology.

β-Hydroxyisovalerylshikonin inhibits IL-1β-induced chondrocyte inflammation via Nrf2 and retards osteoarthritis in mice.

Xiaolei Zhang, Xiangyang Wang, Weiyang Gao, 2020, Food & function.

Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration

Xiaolei Zhang, Xiangyang Wang, Gang Zheng, 2018, Experimental & Molecular Medicine.

Proliferation of rabbit chondrocyte and inhibition of IL-1β-induced apoptosis through MEK/ERK signaling by statins

Bin Zhou, Huazi Xu, Xiaolei Zhang, 2017, In Vitro Cellular & Developmental Biology - Animal.

RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2020, Frontiers in Cell and Developmental Biology.

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Zengjie Zhang, Xiaolei Zhang, Xiangyang Wang, 2018, Experimental & Molecular Medicine.

Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice

Di Zhang, Sheng Wang, Xiaolei Zhang, 2022, Cell Death & Disease.

Targeting mitochondrial dysfunction with small molecules in intervertebral disc aging and degeneration

A. Mobasheri, Xiaolei Zhang, M. Saberi, 2021, GeroScience.

The amelioration of cartilage degeneration by ADAMTS-5 inhibitor delivered in a hyaluronic acid hydrogel.

Shouan Zhu, H. Ouyang, Xiaolei Zhang, 2014, Biomaterials.

Monotropein promotes angiogenesis and inhibits oxidative stress‐induced autophagy in endothelial progenitor cells to accelerate wound healing

Huazi Xu, Jianxiang Xu, Zengjie Zhang, 2017, Journal of cellular and molecular medicine.

Effects of hypoxia on differentiation of menstrual blood stromal stem cells towards tenogenic cells in a co-culture system with Achilles tendon cells

Xiaolei Zhang, Jianjun Hong, Xuqi Hu, 2017, Experimental and therapeutic medicine.

Differentiation of Menstrual Blood–Derived Stem Cells Toward Nucleus Pulposus-Like Cells in a Coculture System With Nucleus Pulposus Cells

Huazi Xu, Xiaolei Zhang, Xuqi Hu, 2014, Spine.

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration

Xiaolei Zhang, Xiangyang Wang, Jiaoxiang Chen, 2017, Pharmacological research.

High glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes

Xiaolei Zhang, Zhenxuan Shao, Jiaoxiang Chen, 2021, Cell Death & Disease.

Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2021, Food & function.

Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats

Zengjie Zhang, Xiaolei Zhang, Xiangyang Wang, 2018, Journal of cellular and molecular medicine.

Effect of Hypoxia on Self-Renewal Capacity and Differentiation in Human Tendon-Derived Stem Cells

Yang Yu, Chuanlu Lin, Yifei Zhou, 2017, Medical science monitor : international medical journal of experimental and clinical research.

Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo

Shouan Zhu, H. Ouyang, B. Heng, 2013, Annals of the rheumatic diseases.

BRD4 inhibition regulates MAPK, NF‐κB signals, and autophagy to suppress MMP‐13 expression in diabetic intervertebral disc degeneration

Xiaolei Zhang, Xiangyang Wang, Zhenxuan Shao, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF‐κB and SIRT6/NF‐κB pathway

Xiaolei Zhang, Xiangyang Wang, Libin Ni, 2023, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Wogonoside inhibits IL-1β induced catabolism and hypertrophy in mouse chondrocyte and ameliorates murine osteoarthritis

Huazi Xu, Jianxiang Xu, Chenggui Wang, 2017, Oncotarget.

IL-37 alleviates intervertebral disc degeneration via the IL-1R8/NF-κB pathway.

Xiaolei Zhang, Xiangyang Wang, Jiaoxiang Chen, 2023, Osteoarthritis and cartilage.

Inhibition of LRRK2 restores Parkin-mediated mitophagy and attenuates intervertebral disc degeneration.

Zengjie Zhang, Xuan-Qi Zheng, Xiaolei Zhang, 2021, Osteoarthritis and cartilage.

ERRATUM: Therapeutic Potential of Naringin for Intervertebral Disc Degeneration: Involvement of Autophagy Against Oxidative Stress-Induced Apoptosis in Nucleus Pulposus Cells.

Zengjie Zhang, Chenggui Wang, Xiaolei Zhang, 2021, The American journal of Chinese medicine.

Dual roles of Misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFβ signaling.

H. Ouyang, Linrong Lu, Yishan Chen, 2019, Osteoarthritis and cartilage.

Effects of calcitriol on experimental spinal cord injury in rats

Kailiang Zhou, Xiaolei Zhang, Haiming Jin, 2016, Spinal Cord.

TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation

Huazi Xu, Zengjie Zhang, Xiaolei Zhang, 2018, Cell Death & Disease.

A novel adhesive dual-sensitive hydrogel for sustained release of exosomes derived from M2 macrophages promotes repair of bone defects

Xiaolei Zhang, Ximiao Chen, Chenchao Li, 2023, Materials today. Bio.

Nrf2 mediated ER-phagy protects against oxidative damage in intervertebral disc degeneration

Xiaolei Zhang, Xiangyang Wang, Zongyou Pan, 2021, bioRxiv.