Michelle Wehling‐Henricks

发表

Differential Effects of Myeloid Cell PPARδ and IL-10 in Regulating Macrophage Recruitment, Phenotype, and Regeneration following Acute Muscle Injury

Steven S. Welc, J. Tidball, Michelle Wehling‐Henricks, 2020, The Journal of Immunology.

Modulation of Klotho expression in injured muscle perturbs Wnt signalling and influences the rate of muscle growth

M. Kuro-o, Steven S. Welc, J. Tidball, 2019, Experimental physiology.

IL-10 Triggers Changes in Macrophage Phenotype That Promote Muscle Growth and Regeneration

J. Tidball, Ying Wang, Michelle Wehling‐Henricks, 2012, The Journal of Immunology.

Evolving Therapeutic Strategies for Duchenne Muscular Dystrophy: Targeting Downstream Events

J. Tidball, Michelle Wehling‐Henricks, 2004, Pediatric Research.

J. Tidball, Michelle Wehling‐Henricks, D. Whittaker, 2012, Aging cell.

Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathway

M. Kuro-o, Steven S. Welc, J. Tidball, 2018, Human molecular genetics.

Regeneration and Phenotype That Promote Muscle Growth IL-10 Triggers Changes in Macrophage

J. Tidball, Michelle Wehling‐Henricks, Bo Deng, 2012 .

Myeloid cell‐derived tumor necrosis factor‐alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers

Steven S. Welc, J. Tidball, Ying Wang, 2018, Aging cell.

Major basic protein-1 promotes fibrosis of dystrophic muscle and attenuates the cellular immune response in muscular dystrophy.

James J. Lee, J. Tidball, Michelle Wehling‐Henricks, 2008, Human molecular genetics.

Myeloid cell-mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of macrophages in muscle

Steven S. Welc, J. Tidball, Michelle Wehling‐Henricks, 2021, Human molecular genetics.

Myeloid cell‐specific mutation of Spi1 selectively reduces M2‐biased macrophage numbers in skeletal muscle, reduces age‐related muscle fibrosis and prevents sarcopenia

Steven S. Welc, J. Tidball, Michelle Wehling‐Henricks, 2022, Aging cell.

Increases of M2a macrophages and fibrosis in aging muscle are influenced by bone marrow aging and negatively regulated by muscle-derived nitric oxide

J. Tidball, Ying Wang, Michelle Wehling‐Henricks, 2015, Aging cell.

Prednisolone decreases cellular adhesion molecules required for inflammatory cell infiltration in dystrophin-deficient skeletal muscle

James J. Lee, J. Tidball, Michelle Wehling‐Henricks, 2004, Neuromuscular Disorders.

IFN-g Promotes Muscle Damage in the mdx Mouse Model of Duchenne Muscular Dystrophy by Suppressing M2 Macrophage Activation and Inhibiting Muscle Cell Proliferation

J. Tidball, C. Rinaldi, Michelle Wehling‐Henricks, 2011 .

Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy

Steven S. Welc, Ying Wang, J. Tidball, 2019, Nature Communications.

Aging of the immune system causes reductions in muscle stem cell populations, promotes their shift to a fibrogenic phenotype, and modulates sarcopenia

Allison L. Fisher, Steven S. Welc, J. Tidball, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Defects in neuromuscular junction structure in dystrophic muscle are corrected by expression of a NOS transgene in dystrophin-deficient muscles, but not in muscles lacking alpha- and beta1-syntrophins.

S. Froehner, J. Tidball, Michelle Wehling‐Henricks, 2004, Human molecular genetics.

Shifts in macrophage cytokine production drive muscle fibrosis

J. Tidball, Michelle Wehling‐Henricks, 2015, Nature Medicine.

muscular dystrophy The role of free radicals in the pathophysiology of

Robert W. Taylor, F. Muntoni, Paul L Huang, 2015 .

Cardiomyopathy in dystrophin-deficient hearts is prevented by expression of a neuronal nitric oxide synthase transgene in the myocardium.

J. Tidball, Michelle Wehling‐Henricks, Bo Deng, 2005, Human molecular genetics.

Loss of positive allosteric interactions between neuronal nitric oxide synthase and phosphofructokinase contributes to defects in glycolysis and increased fatigability in muscular dystrophy.

J. Tidball, C. Rinaldi, Michelle Wehling‐Henricks, 2009, Human molecular genetics.

Expression of a NOS transgene in dystrophin-deficient muscle reduces muscle membrane damage without increasing the expression of membrane-associated cytoskeletal proteins.

J. Tidball, Michelle Wehling‐Henricks, 2004, Molecular genetics and metabolism.

Damage and inflammation in muscular dystrophy: potential implications and relationships with autoimmune myositis

J. Tidball, Michelle Wehling‐Henricks, 2005, Current opinion in rheumatology.

Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo

J. Tidball, Michelle Wehling‐Henricks, James G. Tidball, 2007, The Journal of physiology.

Shared signaling systems in myeloid cell-mediated muscle regeneration

J. Tidball, Michelle Wehling‐Henricks, K. Dorshkind, 2014, Development.

Nitric oxide synthase deficiency and the pathophysiology of muscular dystrophy

J. Tidball, Michelle Wehling‐Henricks, 2014, The Journal of physiology.

Immunobiology of Inherited Muscular Dystrophies.

Steven S. Welc, J. Tidball, Michelle Wehling‐Henricks, 2018, Comprehensive Physiology.

Neuronal Nitric Oxide Synthase-Rescue of Dystrophin/Utrophin Double Knockout Mice does not Require nNOS Localization to the Cell Membrane

J. Tidball, Michelle Wehling‐Henricks, 2011, PloS one.

Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy.

N. Khanlou, M. Kuro-o, Steven S. Welc, 2016, Human molecular genetics.

Arginine Metabolism by Macrophages Promotes Cardiac and Muscle Fibrosis in mdx Muscular Dystrophy

W. Grody, T. Gotoh, J. Tidball, 2010, PloS one.

The role of free radicals in the pathophysiology of muscular dystrophy.

J. Tidball, Michelle Wehling‐Henricks, 2007, Journal of applied physiology.

IFN-γ Promotes Muscle Damage in the mdx Mouse Model of Duchenne Muscular Dystrophy by Suppressing M2 Macrophage Activation and Inhibiting Muscle Cell Proliferation

J. Tidball, C. Rinaldi, Michelle Wehling‐Henricks, 2011, The Journal of Immunology.

Activation and Inhibiting Muscle Cell Dystrophy by Suppressing M 2 Macrophage Mouse Model of Duchenne Muscular mdx Promotes Muscle Damage in the γ IFN-Wehling-Henricks

J. Tidball, C. Rinaldi, Michelle Wehling‐Henricks, 2011 .

Aging of the immune system and impaired muscle regeneration: A failure of immunomodulation of adult myogenesis

Steven S. Welc, J. Tidball, Michelle Wehling‐Henricks, 2020, Experimental Gerontology.

The anti‐aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway

Douglas J. Chapski, T. Vondriska, M. Kuro-o, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy

Steven S. Welc, J. Tidball, Ying Wang, 2019, Nature Communications.

Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging

G. Farrugia, M. Kuro-o, D. R. Linden, 2020, Cellular and molecular gastroenterology and hepatology.

IFN-γ Promotes Muscle Damage in the mdx Mouse Model of Duchenne Muscular Dystrophy by Suppressing M2 Macrophage Activation and Inhibiting Muscle Cell Proliferation

J. Tidball, C. Rinaldi, Michelle Wehling‐Henricks, 2011, The Journal of Immunology.

Klotho regulates the myogenic response of muscle to mechanical loading and exercise

J. Tidball, Michelle Wehling‐Henricks, E. Ochi, 2023, Experimental physiology.