B. Zegers

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Serum immunoglobulin levels in healthy children and adults.

J. W. Stoop, B. Zegers, P. Sander, 1969, Clinical and experimental immunology.

Structural basis for pleckstrin homology domain mutations in X-linked agammaglobulinemia.

M. Zvelebil, M. Vihinen, H. Ochs, 1995, Biochemistry.

Infant B cell responses to polysaccharide determinants.

B. Zegers, G. Rijkers, E. Sanders, 1998, Vaccine.

Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccines

J. Poolman, B. Zegers, G. Rijkers, 1991, Infection and immunity.

T and B cell development in pituitary deficient insulin-like growth factor-II transgenic dwarf mice.

B. Zegers, R. Kooijman, S. van Buul-Offers, 1997, The Journal of endocrinology.

Autoreactivity to human heat-shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis.

W. Kuis, W. van Eden, R. van der Zee, 1996, Arthritis and rheumatism.

Juvenile chronic arthritis: T cell reactivity to human HSP60 in patients with a favorable course of arthritis.

P. Helders, W. Kuis, W. van Eden, 1995, The Journal of clinical investigation.

Antibodies to Human HSP60 in Patients with Juvenile Chronic Arthritis, Diabetes Mellitus, and Cystic Fibrosis

W. Kuis, W. Eden, B. Zegers, 1993, Pediatric Research.

Mechanisms of host defense against infection with Streptococcus pneumoniae.

R. van Furth, G. Bruyn, B. Zegers, 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Expression of type I insulin-like growth factor receptors on human peripheral blood mononuclear cells.

C. Heijnen, B. Zegers, A. Schuurmans, 1992, Endocrinology.

Disorders of cells of the myelo-monocyte cell lineage and of the complement system: molecular basis and clinical aspects.

W. Kuis, B. Zegers, G. Rijkers, 1989, Current opinion in immunology.

Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis

J. Bijlsma, W. Kuis, H. Schuurman, 1991, The Lancet.

Human B Lymphocyte In Vitro Response to the Group B Streptococcal Type III Capsular Carbohydrate

B. Zegers, G. Rijkers, R. Feldman, 1993, Scandinavian journal of immunology.

A comparative study of the immunogenicity of pneumococcal type 4 polysaccharide and oligosaccharide tetanus toxoid conjugates in adult mice.

J. Poolman, B. Zegers, G. Rijkers, 1991, Journal of immunology.

The group B streptococcal capsular carbohydrate: immune response and molecular mimicry.

B. Zegers, G. Rijkers, S. David, 1998, Advances in experimental medicine and biology.

The amplifier role of T cells in the human in vitro B cell response to type 4 pneumococcal polysaccharide.

F. Claas, A. Griffioen, B. Zegers, 1992, Immunology letters.

Two distinct genetic loci regulating class II gene expression are defective in human mutant and patient cell lines.

J. Strominger, B. Zegers, Z. Yang, 1988, The EMBO journal.

Serum immunoglobulins in healthy children and adults. Levels of the five classes, expressed in international units per millilitre.

J. W. Stoop, B. Zegers, P. Sander, 1975, Clinica chimica acta; international journal of clinical chemistry.

Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections.

J. V. D. van de Winkel, B. Zegers, P. Capel, 1994, The Journal of infectious diseases.

Antibodies to the mycobacterial 65-kd heat-shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis.

W. Kuis, W. van Eden, R. Maini, 1990, The American journal of pathology.

Immunological findings in growth hormone-treated patients.

J. Wit, B. Zegers, G. Rijkers, 1993, Hormone research.

Pneumococcal conjugate vaccine primes for polysaccharide-inducible IgG2 antibody response in children with recurrent otitis media acuta.

B. Zegers, G. Rijkers, M. Breukels, 1999, The Journal of infectious diseases.

Purine nucleoside phosphorylase deficiency associated with selective cellular immunodeficiency.

S. K. Wadman, J. W. Stoop, B. Zegers, 1977, The New England journal of medicine.

Defective antipneumococcal polysaccharide antibody response in children with recurrent respiratory tract infections.

W. Kuis, B. Zegers, G. Rijkers, 1993, The Journal of allergy and clinical immunology.

Anti-capsular polysaccharide antibody deficiency states.

B. Zegers, G. Rijkers, L. Sanders, 1993, Immunodeficiency.

Purine nucleoside phosphorylase deficiency associated with cellular immunodeficiency: immunological studies during treatment

S. K. Wadman, J. W. Stoop, B. Zegers, 1979 .

Alpha-chain disease with involvement of the respiratory tract in a Dutch child.

J. W. Stoop, B. Zegers, R. Ballieux, 1971, Clinical and experimental immunology.

Human immunoglobulin G (IgG) Fc receptor IIA (CD32) polymorphism and IgG2-mediated bacterial phagocytosis by neutrophils

R. Feldman, J. V. D. van de Winkel, B. Zegers, 1995, Infection and immunity.

Clinical and immunological studies in patients with an increased serum IgD level

J. Meer, T. Out, B. Zegers, 1989, Journal of Clinical Immunology.

T cell development in a major histocompatibility complex class II‐deficient patient

W. Kuis, P. J. van den Elsen, B. Zegers, 1993, European journal of immunology.

Rapid Communication Antibodies to the Mycobacterial 65-kd Heat-shock Protein Are Reactive with Synovial Tissue of Adjuvant Arthritic Rats and Patients with Rheumatoid Arthritis and Osteoarthritis

W. Kuis, W. Eden, B. Zegers, 2007 .

GENE DELETION AND GENE DUPLICATION WITHIN THE CLUSTER OF HUMAN HEAVY‐CHAIN GENES: SELECTIVE ABSENCE OF IgG SUB‐CLASSES

R. Sukernik, L. Osipova, B. Zegers, 1980, Journal of immunogenetics.

Altered antigen-presentation in the induction of the in-vitro antigen-specific T helper cell function in patients with chronic granulomatous disease.

J. V. D. van der Meer, C. Heijnen, B. Zegers, 1986, Clinical and experimental immunology.

ACRODERMATITIS ENTEROPATHICA AND CELLULAR IMMUNE DEFICIENCY

J. V. Gool, B. Zegers, B. Zegers, 1976, The Lancet.

Expression and modulation of cell surface determinants on human adult and neonatal monocytes.

B. Zegers, G. Rijkers, P. Marwitz, 1988, Clinical and experimental immunology.

The in Vitro B‐Cell Response to Pneumococcal Polysaccharides in Adults and Neonates

B. Zegers, E. Dollekamp, G. Rukers, 1987, Scandinavian journal of immunology.

Metabolic Causes of Immune Deficiency: Mechanisms and Treatment

J. W. Stoop, B. Zegers, 1988 .

Placental diagnosis of the "bare lymphocyte" syndrome.

H. Schuurman, B. Zegers, J. Roord, 1985, The New England journal of medicine.

Erythrocyte metabolism in purine nucleoside phosphorylase deficiency after enzyme replacement therapy by infusion of erythrocytes.

D. Martin, S. K. Wadman, J. W. Stoop, 1980, The Journal of clinical investigation.

Analysis of purine nucleoside phosphorylase from human T and non-T lymphocytes of different maturation stages.

B. Zegers, G. Staal, G. Rijksen, 1983, Clinical biochemistry.

Therapy in adenosine deaminase and purine nucleoside phosphorylase deficient patients.

J. W. Stoop, B. Zegers, 1983, Clinical biochemistry.

Measurement of cytoplasmic calcium in lymphocytes using flow cytometry. Kinetic studies and single cell analysis.

A. Griffioen, B. Zegers, G. Rijkers, 1989, Journal of immunological methods.

A patient with purine nucleoside phosphorylase deficiency: enzymological and metabolic aspects.

S. K. Wadman, J. Akkerman, J. W. Stoop, 1977, Clinica chimica acta; international journal of clinical chemistry.

Selective severe cellular immunodeficiency. Effect of thymus transplantation and transfer factor administration.

J. W. Stoop, B. Zegers, R. Ballieux, 1976, Clinical immunology and immunopathology.

Quantitation of human IgG subclass antibodies to Haemophilus influenzae type b capsular polysaccharide. Results of an international collaborative study using enzyme immunoassay methodology.

O. Mäkelä, C. Frasch, J. Nagel, 1992, Journal of immunological methods.

CD40lbase: a database of CD40L gene mutations causing X-linked hyper-IgM syndrome.

A. Villa, M. Vihinen, S. Giliani, 1996, Immunology today.

Immunologic studies in Turner syndrome before and during treatment with growth hormone. The Dutch Growth Hormone Working Group.

J. Wit, J. van den Brande, B. Zegers, 1991, The Journal of pediatrics.

Ligation of membrane immunoglobulin leads to inactivation of the signal-transducing ability of membrane immunoglobulin, CD19, CD21, and B-cell gp95.

A. Griffioen, J. Cambier, B. Zegers, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Human T cell repertoire generation in the absence of MHC class II expression results in a circulating CD4+CD8- population with altered physicochemical properties of complementarity-determining region 3.

O. Sanal, F. Ersoy, P. J. van den Elsen, 1996, Journal of immunology.

Heterogeneity of immune defects in three children with a chronic active Epstein-Barr virus infection

W. Kuis, A. Rickinson, J. Kapsenberg, 1985, Journal of Clinical Immunology.

Monoclonal gammopathy in a child with leukemia.

J. W. Stoop, B. Zegers, R. Ballieux, 1968, Blood.

A New Case of Purine Nucleoside Phosphorylase Deficiency: Enzymologic, Clinical, and Immunologic Characteristics

W. Kuis, M. Durán, S. K. Wadman, 1987, Pediatric Research.

Subclass restriction pattern of antigen-specific antibodies in donors with defective expression of IgG or IgA subclass heavy chain constant region genes.

L. Hammarström, C. I. Smith, B. Zegers, 1987, Clinical immunology and immunopathology.

MOLECULAR ANALYSIS OF A CASE OF IgA2 DEFICIENCY

B. Bast, O. Carbonara, S. Oliviero, 1986, Journal of immunogenetics.

Selective deficiency of immunoglobulin A2.

B. Zegers, L. Kater, E. Bast, 1983, The Journal of clinical investigation.

HL‐A Typing in Families of Potential Kidney Recipients

M. Overbeeke, B. Zegers, B. Planque, 1973, Vox sanguinis.

Defective T suppressor-inducer cell function in human immune deficiency virus-seropositive hemophilia patients.

C. Heijnen, J. W. Stoop, B. Zegers, 1988, Blood.

Functional and mechanistic studies on the toxicity of deoxyguanosine for the in vitro proliferation and differentiation of human peripheral blood B lymphocytes

M. Durán, B. Zegers, G. Staal, 1986, European journal of immunology.

Different pathways for deoxyguanosine toxicity in T-lymphocytes of various developmental stages.

M. Durán, B. Zegers, G. Staal, 1988, International journal of immunopharmacology.

Mechanisms of deoxyguanosine toxicity for human T and B lymphocytes.

S. K. Wadman, B. Zegers, G. Staal, 1986, Advances in experimental medicine and biology.

The effect of deoxyguanosine on human lymphocyte function. I. Analysis of the interference with lymphocyte proliferation in vitro.

S. K. Wadman, J. W. Stoop, B. Zegers, 1984, Journal of immunology.

Lymphocyte Dysfunctions Associated with Enzyme Defects

W. Kuis, J. W. Stoop, B. Zegers, 1984 .

Monoclonal gammopathy (IgG) and chronic ulcerative dermatitis (phagedenic pyoderma).

B. Zegers, H. Hart, J. Imhof, 2009 .

CONGENITAL ICHTHYOSIS: CONCURRENT IMMUNODEEICIENCY AND ATYPICAL T CELLS

J. W. Stoop, B. Zegers, G. Hendrickx, 1979, International journal of dermatology.

Pathology of congenital immunodeficiencies.

H. Schuurman, B. Zegers, J. Huber, 1992, Seminars in diagnostic pathology.

Quantification of IgG subclasses in sera of normal adults and healthy children between 4 and 12 years of age.

M. van der Giessen, T. van Veen, B. Zegers, 1975, Clinical and experimental immunology.

Letter: Acrodermatitis enteropathica and cellular immune deficiency.

B. Zegers, J. V. van Gool, K. Went, 1976, Lancet.

Home treatment in patients with antibody deficiency by slow subcutaneous infusion of gammaglobulin.

W. Kuis, R. van Furth, J. W. Stoop, 1982, Lancet.

Acute phase reactants and complement components as indicators of recurrence in human cervical cancer.

B. Zegers, R. Ballieux, B. Zegers, 1979, European journal of cancer.

A study on phospholipid exchange proteins present in the soluble fractions of beef liver and brain.

K. Wirtz, L. van Deenen, B. Zegers, 1973, Biochimica et biophysica acta.

Cord serum levels of IgM, IgA, and alpha-fetoprotein and their interrelationships.

H. Schuurman, B. Zegers, A. Hagenaars, 1977, Clinica chimica acta; international journal of clinical chemistry.

Application of specialized techniques for specific staining of peptide maps on various media.

B. Zegers, C. W. Easley, M. De Vijlder, 1969, Biochimica et biophysica acta.

Studies on Fd-fragments of human immunoglobulins. II. The preparation and characterization of peptic (Fab')2-fragments and an Fd'-fragment of IgA-myeloma proteins.

B. Zegers, R. Ballieux, J. J. van der Sluis, 1974, Biochimica et biophysica acta.

The effect of deoxycytidine and tetrahydrouridine in purine nucleoside phosphorylase deficiency.

W. Kuis, M. Durán, S. K. Wadman, 1984, Advances in experimental medicine and biology.

Defect in B cell function in HTLV III/LAV positive hemophilia patients

C. Heijnen, J. W. Stoop, B. Zegers, 1987 .

Defect in B cell function in HTLV III/LAV positive hemophilia patients.

C. Heijnen, J. W. Stoop, B. Zegers, 1987, Blood.

Comparative studies on polymer-type serum and exocrine IgA.

J. W. Stoop, B. Zegers, R. Ballieux, 2009, Scandinavian journal of haematology.

Pathology of immunoglobulins. Some aspects of monoclonal gammopathy.

J. W. Stoop, B. Zegers, R. Ballieux, 1968, Clinica chimica acta; international journal of clinical chemistry.

T cell development in insulin-like growth factor-II transgenic mice.

H. Schuurman, B. Zegers, R. Kooijman, 1995, Journal of immunology.

Pneumococcal conjugate vaccines.

B. Haagmans, J. Poolman, B. Zegers, 1991, Immunology letters.

Identification of novel Bruton's tyrosine kinase mutations in 10 unrelated subjects with X linked agammaglobulinaemia.

M. Tilanus, J. K. V. van Amstel, R. Brooimans, 1997, Journal of medical genetics.

Cardiopulmonary bypass and host defense functions in human beings: II. Lymphocyte function.

C. Heijnen, B. Zegers, R. Ballieux, 1985, The Annals of thoracic surgery.

Pneumococcal polysaccharides complexed with C3d bind to human B lymphocytes via complement receptor type 2

A. Griffioen, B. Zegers, G. Rijkers, 1991, Infection and immunity.

Revised exon–intron structure of human JAK3 locus

R. Brooimans, B. Zegers, A. V. D. Slot, 1999, European Journal of Human Genetics.

An approach to the restoration of T cell function in a purine nucleoside phosphorylase deficient patient.

S. K. Wadman, J. W. Stoop, B. Zegers, 1978, Ciba Foundation symposium.

Mononuclear cells in S-phase in a patient with purine nucleoside phosphorylase deficiency.

W. Kuis, J. W. Stoop, B. Zegers, 1984, Advances in experimental medicine and biology.

The thymus in "bare lymphocyte" syndrome.

H. Schuurman, B. Zegers, L. Kater, 1985, Advances in experimental medicine and biology.

Urinary excretion of orotic acid, orotidine and other pyrimidines in a patient with purine nucleoside phosphorylase deficiency.

S. K. Wadman, J. W. Stoop, B. Zegers, 1979, Clinica chimica acta; international journal of clinical chemistry.

Purine nucleoside phosphorylase deficiency associated with cellular immunodeficiency: metabolic studies during treatment

S. K. Wadman, J. W. Stoop, B. Zegers, 1979 .

Red cell metabolism in purine nucleoside phosphorylase deficiency after enzyme replacement therapy.

S. K. Wadman, J. W. Stoop, B. Zegers, 1978, Monographs in human genetics.

Urinary purines in a patient with a severely defective T cell immunity and a purine nucleoside phosphorylase deficiency.

S. K. Wadman, J. W. Stoop, B. Zegers, 1977, Advances in experimental medicine and biology.

An abnormal form of purine nucleoside phosphorylase in a family with a child with severe defective T-cell-and normal B-cell immunity.

J. W. Stoop, B. Zegers, G. Staal, 1976, Clinica chimica acta; international journal of clinical chemistry.

Inherited deficiency of the third component of complement associated with recurrent pyogenic infections, circulating immune complexes, and vasculitis in a Dutch family.

W. Kuis, M. Daha, H. Verbrugh, 1983, Pediatrics.

The Wiskott‐Aldrich syndrome: studies on a possible defect in mitochondrial ATP resynthesis in platelets

W. Kuis, B. Zegers, J. Akkerman, 1982, British journal of haematology.

Aberrant recombination events in B cell lines derived from a kappa-deficient human.

J. Grenier, J. Stavnezer, D. Batter, 1985, Nucleic acids research.

Cardiopulmonary bypass and host defense functions in human beings: I. Serum levels and role of immunoglobulins and complement in phagocytosis.

H. Verbrugh, J. Verhoef, B. Zegers, 1985, The Annals of thoracic surgery.

Molecular defects in a human immunoglobulin kappa chain deficiency.

B. Zegers, J Stavnezer-Nordgren, O Kekish, 1985, Science.

Antibody Response in Hodgkin's Disease and Other Lymphomas Related to HL‐A Antigens, Immunoglobulin Levels and Therapy

B. Zegers, E. Borst‐Eilers, J. Sybesma, 1973, Vox sanguinis.

AGAMMAGLOBULINEMIA ASSOCIATED WITH THE OCCURRENCE OF A MONOCLONAL IMMUNOGLOBULIN

B. Zegers, J. Stoop, G. Hendrickx, 1979, Acta paediatrica Scandinavica.

Role of CR2 in the human adult and neonatal in vitro antibody response to type 4 pneumococcal polysaccharide.

A. Griffioen, B. Zegers, G. Rijkers, 1992, Cellular immunology.

Antigen-induced plaque-forming cell responses in cultures of peripheral blood mononuclear cells of human neonates and infants.

B. Zegers, R. Ballieux, M. V. van Tol, 1984, The Journal of pediatrics.

Defective expression of mononuclear cell membrane HLA antigens associated with combined immunodeficiency: impaired cellular interactions.

W. Kuis, C. Heijnen, J. W. Stoop, 1983, Birth defects original article series.

Lysogenic Conversion of Staphylococci to Loss of β-Toxin.

B. Zegers, K. Winkler, J. D. Waart, 1965 .

Studies on Fd-fragments of human immunoglobulins. I. A Comparative peptide mapping study on L-chains, Fab- and Fd-fragments of G-myeloma proteins.

B. Zegers, R. Ballieux, C. W. Easley, 1970, Biochimica et biophysica acta.

Interference of deoxyadenosine with transmembrane signaling events in human T lymphocytes.

J. Akkerman, B. Zegers, G. Staal, 1990, International journal of immunopharmacology.

Immunoglobulin determination. Evaluation of the results of immunoelectrophoretic analysis and the radial diffusion method.

J. W. Stoop, B. Zegers, R. Ballieux, 1968, Clinica chimica acta; international journal of clinical chemistry.

IGF-I potentiates interleukin-2 production in human peripheral T cells.

B. Zegers, G. Rijkers, R. Kooijman, 1996, The Journal of endocrinology.

Type I insulin-like growth factor receptor expression in different developmental stages of human thymocytes.

B. Zegers, G. Rijkers, R. Kooijman, 1995, The Journal of endocrinology.

8-Mercaptoguanosine overcomes unresponsiveness of human neonatal B cells to polysaccharide antigens.

B. Zegers, G. Rijkers, I. Dollekamp, 1988, Journal of immunology.

Antigen receptor-mediated transmembrane signaling in Wiskott-Aldrich syndrome.

B. Zegers, G. Rijkers, N. Henriquez, 1994, Journal of immunology.

Cell biology of B lymphocyte activation by polysaccharides.

A. Griffioen, B. Zegers, G. Rijkers, 1992, Journal of Infectious Diseases.

The serum IgG subclass levels in healthy infants of 13--62 weeks of age.

M. van der Giessen, J. W. Stoop, B. Zegers, 1980, Clinica chimica acta; international journal of clinical chemistry.

Inhibition of in vitro lymphocyte proliferation and B cell differentiation by deoxyguanosine: evidence for separate mechanisms.

W. Kuis, M. Durán, B. Zegers, 1984, Advances in Experimental Medicine and Biology.

Human lymphocytic ecto-5'-NT: its determination and partial characterization.

B. Zegers, G. Staal, G. Rijksen, 1984, Advances in Experimental Medicine and Biology.

Heat-shock proteins and juvenile chronic arthritis.

W. Kuis, W. van Eden, B. Zegers, 1993, Clinical and experimental rheumatology.

Immunogenicity of a Streptococcus pneumoniae type 4 polysaccharide--protein conjugate vaccine is decreased by admixture of high doses of free saccharide.

J. Poolman, B. Zegers, G. Rijkers, 1992, Vaccine.

In vitro induction of a Haemophilus influenzae type b polysaccharide-specific antibody response in human peripheral blood lymphocytes of individuals recently vaccinated with an oligosaccharide-protein conjugate.

J. Poolman, C. Heijnen, B. Zegers, 1991, Journal of immunology.

Familial presence of primary cryofibrinogenaemia, a report of three cases.

W. Kuis, B. Zegers, N. Wulffraat, 1996, British journal of rheumatology.

Kappa-chain deficiency. An immunoglobulin disorder.

J. W. Stoop, B. Zegers, R. Ballieux, 1976, The New England journal of medicine.

Distinct role of neonatal and adult monocytes in the regulation of the in vitro antigen-induced plaque-forming cell response in man.

B. Zegers, R. Ballieux, M. V. van Tol, 1984, Journal of immunology.

Deficiency of the beta subunit of the eighth component of complement presenting as arthritis and exanthem.

W. Kuis, B. Zegers, N. Wulffraat, 1994, Arthritis and rheumatism.

Membranoproliferative glomerulonephritis in a patient with congenital deficiency of the third component of complement: effect of treatment with plasma.

H. Schuurman, J. W. Stoop, B. Zegers, 1989, American journal of kidney diseases : the official journal of the National Kidney Foundation.

The thymus in "bare lymphocyte" syndrome: significance of expression of major histocompatibility complex antigens on thymic epithelial cells in intrathymic T-cell maturation.

H. Schuurman, B. Zegers, L. Kater, 1985, Human immunology.

Fc gamma IIA receptor phenotype and opsonophagocytosis in two patients with recurrent bacterial infections.

R. Feldman, J. V. D. van de Winkel, B. Zegers, 1993, Immunodeficiency.

Studies on the antigenic properties of the Fd-fragment of a human G-myeloma protein (DAW).

B. Zegers, R. Ballieux, 1967, Immunochemistry.

Studies on Fd Fragments of Human Immunoglobulins

B. Zegers, R. Ballieux, E. Loghem, 1975 .

Increased Serum IgA in Intestinal Disease

J. W. Stoop, B. Zegers, R. Ballieux, 1969 .

Serum Immunoglobulin Levels in Trio and Wajana Indians of Surinam

B. Zegers, P. Sander, R. Geerdink, 1973, Vox sanguinis.