B. Murphy

发表

Islet‐expressed TLR2 and TLR4 sense injury and mediate early graft failure after transplantation

W. Coward, G. Lal, J. Bromberg, 2010, European journal of immunology.

Analysis of Biomarkers Within the Initial 2 Years Posttransplant and 5-Year Kidney Transplant Outcomes: Results From Clinical Trials in Organ Transplantation-17

P. Nickerson, D. Rush, G. Nadkarni, 2017, Transplantation.

Role of donor-derived monocyte chemoattractant protein-1 in murine islet transplantation.

J. Bromberg, B. Schröppel, N. Zhang, 2005, Journal of the American Society of Nephrology : JASN.

Glomerular Infiltration by CXCR3+ ICOS+ Activated T Cells in Chronic Allograft Nephropathy with Transplant Glomerulopathy

S. Dikman, W. Hancock, J. Bromberg, 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Indirect allorecognition of donor class I and II major histocompatibility complex peptides promotes the development of transplant vasculopathy.

M. Sayegh, J. Stone, A. Chandraker, 2001, Journal of the American Society of Nephrology : JASN.

Major histocompatibility complex–derived peptides as novel forms of immunosuppression

M. Sayegh, A. Waaga, B. Murphy, 1999 .

SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts.

J. Wong, J. He, P. Cravedi, 2018, Journal of the American Society of Nephrology : JASN.

Design and Implementation of the International Genetics and Translational Research in Transplantation Network

Graham M Lord, Jason H. Moore, W. Guan, 2015, Transplantation.

APOL1 high‐risk genotypes and renal transplantation

R. Shapiro, B. Murphy, Sapna Shah, 2019, Clinical transplantation.

Monocytic Myeloid‐Derived Suppressor Cells Accumulate in Renal Transplant Patients and Mediate CD4+Foxp3+ Treg Expansion

J. Ochando, B. Murphy, D. Wilson, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Acquired systemic tolerance to rat cardiac allografts induced by intrathymic inoculation of synthetic polymorphic MHC class I allopeptides.

M. Sayegh, B. Murphy, M. Hardy, 1996, Transplantation.

Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach

Li Li, Brian A. Kidd, Joel T. Dudley, 2017, Scientific Reports.

HLA-derived peptides as novel immunomodulatory therapeutics.

A. Krensky, B. Murphy, 1999, Journal of the American Society of Nephrology : JASN.

The Association of IL28B Polymorphism and Graft Survival in Patients with Hepatitis C Undergoing Liver Transplantation

T. Schiano, A. Mehrotra, B. Schröppel, 2013, PloS one.

A novel mechanism for the immunomodulatory functions of class II MHC-derived peptides.

T. Chitnis, M. Sayegh, M. Lin, 2003, Journal of the American Society of Nephrology : JASN.

Cardiac Surveillance Whilst Listed for Renal Transplantation

B. Murphy, M. Menon, K. Keung, 2017 .

Complement component C3 allotypes and outcomes in liver transplantation

T. Schiano, J. Godbold, A. Mehrotra, 2010, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Immune Reconstitution Following Rabbit Antithymocyte Globulin

J. Bromberg, P. Heeger, R. Dinavahi, 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

The Role of Macrophages in the Development of Human Renal Allograft Fibrosis in the First Year After Transplantation

J. Chapman, S. Alexander, P. O’Connell, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

The Impact of Polymorphisms in Chemokine and Chemokine Receptors on Outcomes in Liver Transplantation

T. Schiano, B. Krämer, M. Fischereder, 2002, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Inhibition of the Alloimmune Response through the Generation of Regulatory T Cells by a MHC Class II-Derived Peptide1

M. Grimm, W. Hancock, M. Lin, 2008, Journal of Immunology.

Class II-Derived Peptide Cellsthrough the Generation of Regulatory T Inhibition of the Alloimmune Response

M. Grimm, W. Hancock, M. Lin, 2008 .

A Monocyte chemoattractant protein-1 (MCP-1) polymorphism and outcome after renal transplantation.

B. Krämer, M. Fischereder, B. Schröppel, 2002, Journal of the American Society of Nephrology : JASN.

Analysis of Gene Polymorphisms in the Regulatory Region of MCP-1, RANTES, and CCR5 in Liver Transplant Recipients

T. Schiano, B. Krämer, M. Fischereder, 2002, Journal of Clinical Immunology.

Costimulatory Blockade‐Induced Allograft Survival Requires Beclin1

P. Heeger, B. Schröppel, A. Yadav, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Kidney Failure Associates With T Cell Exhaustion and Imbalanced Follicular Helper T Cells

P. Cravedi, L. Gallon, Weijia Zhang, 2020, Frontiers in Immunology.

The Impact of Costimulatory Molecule Gene Polymorphisms on Clinical Outcomes in Liver Transplantation

T. Schiano, Y. Tomer, R. Parekh, 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Adenovirus Transduction Induces Expression of Multiple Chemokines and Chemokine Receptors in Murine β Cells and Pancreatic Islets

N. Zhang, S. Fu, K. Hudkins, 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

The indirect pathway of allorecognition. The occurrence of self-restricted T cell recognition of allo-MHC peptides early in acute renal allograft rejection and its inhibition by conventional immunosuppression.

M. Sayegh, E. Akalin, C. Carpenter, 1995, Transplantation.

Maintenance immunosuppression in renal transplantation.

B. Murphy, M. Menon, 2013, Current opinion in pharmacology.

MHC Class II-mediated apoptosis by a nonpolymorphic MHC Class II peptide proceeds by activation of protein kinase C.

M. Lin, W. Zang, B. Murphy, 2005, Journal of the American Society of Nephrology : JASN.

MHC Class II – Mediated Apoptosis by a Nonpolymorphic MHC Class II Peptide Proceeds by Activation of Protein Kinase

M. Lin, W. Zang, B. Murphy, 2005 .

Mechanisms of indirect allorecognition in graft rejection: class II MHC allopeptide-specific T cell clones transfer delayed-type hypersensitivity responses in vivo.

S. Khoury, M. Sayegh, M. Russell, 1996, Transplantation.

Immunomodulatory functions of low-molecular weight hyaluronate in an acute rat renal allograft rejection model.

M. Sayegh, M. Denton, C. Magee, 1999, Journal of the American Society of Nephrology : JASN.

Induction of transplant tolerance by intrathymic inoculation of synthetic MHC class I allopeptides.

M. Sayegh, B. Murphy, M. Hardy, 1997, Transplantation proceedings.

AMPK mediates regulation of glomerular volume and podocyte survival

L. Cantley, S. Ishibe, J. He, 2021, JCI insight.

AMP-Kinase mediates regulation of glomerular volume and podocyte survival

L. Cantley, S. Ishibe, J. He, 2021, bioRxiv.

Moving Biomarkers toward Clinical Implementation in Kidney Transplantation.

P. Heeger, B. Murphy, M. Menon, 2017, Journal of the American Society of Nephrology : JASN.

A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection.

Zeguo Sun, R. Colvin, E. Lerut, 2019, Journal of the American Society of Nephrology : JASN.

Class II MHC allopeptide-specific T-cell clones transfer delayed type hypersensitivity responses in vivo.

S. Khoury, M. Sayegh, A. Waaga, 1997, Transplantation proceedings.

Why do we reject a graft? Mechanisms of recognition of transplantation antigens

M. Sayegh, B. Murphy, 1996 .

Inhibition of TLR4 signaling prolongs Treg-dependent murine islet allograft survival.

M. Grimm, G. Lal, J. Bromberg, 2010, Immunology letters.

Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study

Yi Luan, Yongchao Ge, R. Colvin, 2016, The Lancet.

Key driver genes as potential therapeutic targets in renal allograft rejection.

S. Alexander, Chengguo Wei, P. O’Connell, 2020, JCI insight.

Biomarkers of Kidney Injury and Rejection

P. O’Connell, B. Murphy, M. Menon, 2019, Kidney Transplantation - Principles and Practice.

Immune Cell–Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin

S. Segerer, M. Lin, P. Heeger, 2010, Diabetes.

Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

Marylyn D. Ritchie, Shefali S. Verma, Kelly A. Birdwell, 2015, Genome Medicine.

Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis.

R. Colvin, Li Li, Rong Chen, 2015, The Journal of clinical investigation.

Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways.

W. Kuziel, K. Hudkins, J. Bromberg, 2004, Journal of the American Society of Nephrology : JASN.

DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity.

K. Zen, V. D’Agati, Zhihong Liu, 2021, The Journal of clinical investigation.

Analysis of the CTLA-4, CD28, and inducible costimulator (ICOS) genes in autoimmune thyroid disease

B Murphy, T F Davies, G. Barbesino, 2003, Genes and Immunity.

Immunology of Organ Transplantation

B. Schröppel, B. Murphy, Sevgi Gurkan, 2009 .

Peptide-mediated immunosuppression.

W. Zang, B. Murphy, 2005, American journal of therapeutics.

Inhibition of allorecognition by a human class II MHC-derived peptide through the induction of apoptosis.

H. Snoeck, S. Alexander, M. Sayegh, 1999, The Journal of clinical investigation.

Indirect allorecognition of major histocompatibility complex allopeptides in human renal transplant recipients with chronic graft dysfunction.

B Murphy, S. Alexander, M. Sayegh, 1997, Transplantation.

Cytokine analysis of human renal allograft aspiration biopsy cultures supernatants predicts acute rejection.

M. Sayegh, B. Murphy, P. Xavier, 1998, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

T cell recognition of xeno-MHC peptides during concordant xenograft rejection.

H. Auchincloss, M. Sayegh, C. Carpenter, 1996, Transplantation.

Genomic Analysis of Kidney Allograft Injury Identifies Hematopoietic Cell Kinase as a Key Driver of Renal Fibrosis.

J. Dudley, B. Kidd, J. He, 2017, Journal of the American Society of Nephrology : JASN.

Gene variants affecting bioavailability of drugs: towards individualized immunosuppressive therapy?

B. Schröppel, B. Murphy, 2003, Journal of the American Society of Nephrology : JASN.

Immunomodulatory Function of MHC Peptides

A. Krensky, B. Murphy, 2001 .

Synthetic MHC class I peptide prolongs cardiac survival and attenuates transplant arteriosclerosis in the Lewis-->Fischer 344 model of chronic allograft rejection.

B Murphy, M. Sayegh, W. Hancock, 1997, Transplantation.

Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity

J G Coen van Hasselt, Jia-Jye Lee, Evren U Azeloglu, 2019, Nature Communications.

Genome-wide non-HLA donor-recipient genetic differences influence renal allograft survival via early allograft fibrosis.

A. Israni, Zeguo Sun, E. Stahl, 2020, Kidney international.

Recipient APOL1 risk alleles associate with death-censored renal allograft survival and rejection episodes

R. Colvin, S. Ishibe, P. O’Connell, 2021, medRxiv.

Routes to allograft survival.

J. Bromberg, B. Murphy, Jonathan S. Bromberg, 2001, The Journal of clinical investigation.

NPHP1 (Nephrocystin-1) Gene Deletions Cause Adult-Onset ESRD.

A. Israni, H. Snieder, B. van der Zwaag, 2018, Journal of the American Society of Nephrology : JASN.

Pretransplant transcriptomic signature in peripheral blood predicts early acute rejection.

Zeguo Sun, R. Colvin, S. Alexander, 2019, JCI insight.

Cytotoxic T-lymphocyte antigen 4 gene polymorphisms and susceptibility to acute allograft rejection.

C. Bodian, T. Schiano, Y. Tomer, 2001, Transplantation.

Genetic variability and transplantation

B. Schröppel, B. Murphy, B. Marder, 2003, Current opinion in urology.

The Use of Genomics and Pathway Analysis in Our Understanding and Prediction of Clinical Renal Transplant Injury.

B. Murphy, M. Menon, K. Keung, 2016, Transplantation.

Inhibition of the alloimmune response with synthetic nonpolymorphic class II MHC peptides.

M. Sayegh, E. Akalin, C. Carpenter, 1995, Transplantation proceedings.

Immunomodulatory function of major histocompatibility complex-derived peptides.

M. Sayegh, B. Murphy, 1996, Current opinion in nephrology and hypertension.